Preliminary program of the FACS SYMPOSIUM Sunday, June 3 rd, 2018 4.00 pm Opening of the registration desk at the Hotel Les Portes de Sologne, Orléans. 5.45 pm Conference opening & welcome remarks Jean Suffert & Nicolas Blanchard David R. Williams & Marc Snapper Session 1 Chairman Dr. SUFFERT 6.00 pm Tomislav ROVIS New tools for catalysis 7.00 pm Jean-François CARPENTIER - ChemPubSoc Europe lecturer Highly Reactive Heavy Alkaline-Earth Complexes for Hydroelementation and Dehydrocoupling Catalysis. 8.15 pm Cocktail mixer & dinner with all participants and sponsors. 1/5
Monday, June 4 th, 2018 Session 2 Chairman Pr. WILLIAMS 8.00 am Scott MILLER Selective Catalytic Reactions in Complex Molecular Environments Inspired by Natural Products 8.55 am Guangbin DONG C-C and C-H Functionalization of Ketones. 9.50 pm Keynote Lecture from Syrris (www.syrris.com) Continuous Electrochemical Synthesis of Metabolites in Flow 10.05 am Coffee Break Session 3 Chairman Dr. BLANCHARD 10.25 am Corinne GOSMINI CoX 2 : an economic alternative catalyst for C-C bond formation 11.20 am Kevin MOELLER From Molecules to Molecular Surfaces: Organic Electrochemistry as Tool for Synthesis 12.15 pm Lunch (Hotel) Session 4 Chairman Pr. SNAPPER 2.00 pm SHORT TALKS 2.00-2.30 pm: Robert KNOWLES - Proton-coupled electron transfer in organic synthesis 2.30-3.00 pm: Antony BIGOT - Scalable synthesis of aza-cryptophycin, a highly active payload for ADC 3.00-3.30 pm: Mary WATSON - Harnessing Alkyl Amines for Nickel-Catalyzed Cross- Coupling Reactions 3.30 pm Frédéric LAMATY Save on solvent: use mechanochemistry 4.25 pm Keynote Lecture from Vapourtec (www.vapourtec.com) New applications using flow chemistry 4.40 pm Coffee Break Session 5 Chairman Pr. GANDON 5.05 pm Martin EASTGATE Innovation in the Synthesis of Complex Pharmaceutical Compounds 6.00 pm Robert DODD Hypervalent Iodine-Promoted Reactions of Olefins and Enamides 6.55 pm Stephen HANESSIAN Art, Craft, Logic and the Unforseen in Organic Synthesis 7.50 pm End of Session 4 8.15 pm Dinner 2/5
Tuesday, June 5 th, 2018 Session 6 Chairman Dr. DONNARD 8.00 am Christophe MEYER From strained rings to macrocycles: Synthetic methods and molecular diversity 8.55 am SHORT TALKS 9.00-9:30 am: Julie BROGGI - Base-free generation of organic electron donors from airstable precursors 9:30-10.00 am: Stephane BOGEN - Design and Optimization of Novel Nucleoside Prodrug Clinical Candidates for the Treatment of HCV Impact on Metabolism and Delivery to Target Tissue 10.00 am Coffee Break Session 7 Chairman Dr. LEBOEUF 10.20 am SHORT TALKS 10:20-10:50 am: Laetitia CHAUSSET-BOISSARIE - Acceleration of Photochemical reaction in flow 10.50-11.20 am: David BERKOWITZ Enzymatic Screening Methods Applied to the Development of Synthetically Useful Catalytic Chemistry 11.20 pm Group Photo 11.30 am Poster Session and buffet 2.00 pm Château de Chambord guided tour 8.15 pm Gala Dinner (Hotel) 3/5
Wednesday, June 6 th, 2018 Session 8 Chairman Pr. CHARETTE 8.00 am Corey STEPHENSON Redox catalysis strategies for complex molecules 8.55 am Isabelle GILLAIZEAU Enamides and nitrogen-containing motifs 9.50 am Coffee Break Session 9 Chairman Pr. RIANT 10.10 am Christopher BODDY Combining Synthesis and Biosynthesis to Access Complex Molecules 11.05 am SHORT TALKS 11.05-11.35 am: Marie-Aude HIEBEL - 3-Vinyl-1,2,4-triazine: a versatile platform to new fused saturated and unsaturated heterocycles 11.35-12.05 am: Jonathan REEVES - New Methodology Development on the Road to a Safe and Scalable Drug Substance Synthesis 12.05-12.35 am: Stefan CHASSAING - Bridging homogeneous and heterogeneous catalysis with zeolites 12.40 pm Lunch (Hotel) Session 10 Chairwoman Pr. ROIZEN 2.00 pm SHORT TALKS 2.00-2.30 pm: Joseph MORAN - Metabolism before Enzymes? 2.30-3.00 pm: Noah BURNS - Synthesis and Study of Noncanonical Membrane Lipids 3.00-3.30 pm: Armen PANOSSIAN - Aryl-aryne coupling An access to atropostereoenriched biphenyls 3.30 pm ChemPubSoc Europe Keynote lecture Haymo ROSS What is ChemPubSoc Europe? 3.45 pm Coffee Break Session 11 Chairman Dr. JOURNOT 4.05 pm Thierry BILLARD Fluoroalkyl groups and heteroatoms: a happy wedding! 5.00 pm James-MORKEN Stereoselective Catalysis with Boron-Based Reagents 5.55 pm Jean-Guy BOITEAU Process development and Kg synthesis of a new pyridine derivative 6.50 pm End of session 10 8.15 pm Dinner (Hotel) 4/5
Thursday, June 7 th, 2018 Session 12 Chairman Dr. DODD 8.00 am André CHARETTE Journey into cyclopropane chemistry and continuous flow synthesis 8.55 am Alain de MESMAEKER Design and Synthesis of Strigolactones derivatives for Crop Enhancement applications using ketene-iminiums as key intermediates 9.50 am Coffee Break 10.10 am SHORT TALKS 10.10-10.40 am: David MARTIN - Vinamidinium salts: old compounds for new challenges 10.40-11.10 am: Corinna SCHINDLER - title 11.10-11.40 am: Christophe AISSA - Cross-coupling of α-carbonyl sulfoxonium ylides with C H bonds 11.40-12.10 am: Marie SCHULER - Glucosinolate-mannoside glycoconjugates as enzymatically triggered masked isothiocyanates : a new tool for bioconjugation? 12.10 am Closing Remarks Jean Suffert & Nicolas Blanchard David R. Williams & Marc Snapper 12.15 am Buffet 2.30 pm Departure 5/5