P wave secs PQ Interval secs QRS Complex secs QT Interval secs
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- Randall Peregrine Hudson
- 5 years ago
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1 c Q Inl c QRS Cplx c QT Inl c lc 5
2 1 Th nd y l p ln Th dny cnl p hh h nn-nnn y Whn h l p ll l, h dny l pn nzy, nn, h c h nn-nnn y nd hlp nc h l p n l y, h hlpn cc h nl ll p Th nn-nnn y c n h lln nn c bld p cnl: A dc n l p l h cn nn h jxll cll h dny n h bld Rnn clyz h cnn nnnn l nnn I Annn I cnd nnn II by h cn cnn nzy pn n h ndhl l hh h bdy, pclly n h ln nd dny Annn II, h py c cpnn h y, pn cnc nd hlp h l p Annn II p n h bld nl pdly ncd by lpl bld nd nzy cllcly clld nnn lc 7 Annn II h pncpl c h cn l h l p: Annn II cnc l nd n hh h bdy Thby ncn l pphl nc nd dcn cl cpcy, hch p ncd n n h h Th c pn pnn xc dcn n bld p dn c ccnc ch hh Annn II dc l nd xcn by h dny Th cn lly nc xclll ld l, hch nc l p pd h nd dy Annn II c l nd nn by h dny n y: Annn c dcly n h dny c l nd nn Annn II cnc h n l, hch dnh bld l hh h pbl cpll, lln pd c bpn h bl In ddn, nnn II dcly l h phll cll h nl bl nc bpn d nd Annn II l h dnl lnd c ldn, nd ldn nc l nd bpn by h phll cll h nl bl
3 Gnl pncpl hnl ln Chy hn S nd cn hn Mchn hnl cn Gnl pncpl hnl ln Th lpl c h cll,, nd n h bdy cdnd by h nply l yp chcl n y: n ld by xn nl nn n h ynpc jncn nd c lclly cnl n cll ncn Endcn hn ld by lnd pclzd cll n h ccln bld nd nlnc h ncn cll nh lcn n h bdy ndcn hn cd by nn n h ccln bld nd nlnc h ncn cll nh lcn n h bdy cn cd by cll n h xclll ld nd c nhbn cll dn yp Acn cd by cll n h xclll ld nd c h ncn h cll h pdcd h by bndn cll c cp Cyn ppd cd by cll n h xclll ld nd cn ncn cn, pcn, ndcn hn lc Th ndcn hn y cll hh h cd by h0ccly bdy, ncldn h n y n c, h hy bnd h cp nd n ny cn S ndcn hn c ny dn yp cll h bdy Oh hn c nly pcc, bc nly h h cp h hn Chy hn S nd cn hn Hn cld ccdn chcl c Chclly, hn nd nhn h yp: n nd ppd Incldd n h p ppd nn ll h n cd (hypn-ln hn) pn l 00 n cd ln (h hn nd plcn) Sd Th d chll nd ncld h dnccl (cl, ldn) nd ndl (n, n, pn) hn D h n cd yn Incldd n h p hn h hyd lnd (hyxn, dhynn) nd dnl dll (pnphn nd npnphn)
4 Th p py lnd nd ln h hyphl hylcl ncn ndc hn nd xycn Th p py lnd nd ln h hyphl Th p py lnd, l clld h nhypphy, cpd nly ll-l cll clld pcyth pcy d n c hn; hy c ply ppn c l nb nl n b nd nl n ndn n c h n n h ppc nd pncl ncl h hyphl Th c p h nhypphy hh h py l Th n ndn blb nb h cnn ny cy nlth ndn l n h c cpll, h hy c p py hn: ndc hn (ADH), l clld pn, nd xycn ADH d ply n h ppc ncl, h xycn d ply n h pncl ncl Whn n pl nd dnd ln h b h ppc pncl ncl, h hn dly ld h cy nl n h n ndn by h l cy chn xcy nd bbd n djcn cpll lc hylcl ncn ADH nd xycn ADH 8 ncn: hylcl Th njcn xly n qn ADH cn c dcd xcn by h dny (nd) In h bnc ADH, h cllcn bl nd dc bc l pbl, hch pn ncn bpn nd h ll x l n h n, l cn x dln h n Cnly, n h pnc ADH, h pbly h cllcn dc nd bl nc ly nd ll h b bbd h bl ld p hh h dc, hby cnn n h bdy nd pdcn y cncnd n Wh ADH, h lnl bn h bl phll cll h cllcn dc l pbl H, dly nd h cll bn l nb pcl cl h h hhly pbl p clld qpn Whn ADH c n h cll, cbn h bn cp h c dnylyl cycl nd c h n cam nd h bl cll cyplth c phphyln ln n h pcl cl, hch hn c h cl n n h pcl cll bn, h pdn
5 ld by hyd-ln hn TSH cn h py lnd ncd by h hypphypc hn hypn-ln hn (TRH) nd nhbd n n dbc hn by ccln T4 nd T Alhh dbc cc h hyphl by nlncn TRH cn, h pdnn dbc cc h ll h py Bc T4 ddnd T n h py lnd, T pp b h nl c h d h n dbc TSH p h ynh nd cn hyd hn Bndn TSH cp n h cll bn h hyd lnd c dnylyl cycl h cyclc AM d h cn TSH An d c TSH p ndcy clld, ply hylbln, nd l T4 nd T n h ccln TSH h chnc c p h h hyd lnd Th chnc c TSH ncld ncd bld l h hyd lnd nd ndcn hypphy nd hyppl h llcl cll Wh plnd TSH ln, h hyd nl, nd cc In h bnc TSH, h d phy h lnd lc 4 4
6 8Th dnl lnd Fncn h nlccd Th dnl lnd Th dnl lnd l h p pl h dny Ech lnd cpd dnc p, h dnl dll nd h dnl cx Th dnl dll ncnlly ld h yphc n y; c h hn pnphn nd npnphn n pn yphc ln In n, h hn c l h c dc ln h yphc n n ll p h bdy Th dnl cx c n nly dn p hn, clld ccdth hn ll ynhzd h d chll Th dnl cx h h dnc ly Th zn ll, hn ly cll h l j ndnh h cpl Th cll c ncn n ldn bc hy cnn h nzy ldn ynh Th cn h cll cnlld nly by h xclll ld cncnn nnn II nd p, bh hch l ldn cn Th zn ccl, h ddl nd d ly, c h lcccd cl nd ccn Th cn h cll cnlld n l p by h hyphlc-py x dnccpc hn (ACTH) Th zn cl, h dp ly h cx, c h dnl ndn dhydpndn (DHEA) nd ndndn ACTH l l cn h cll Th chn cnlln dnl ndn pdcn, h, n ll ndd lc 4 5 Fncn h nlccd- Aldn Mnlccd dcncy c nl d chld n nd hypl Wh nlccd, p n cncnn h xclll ld dly, d nd chld pdly l h bdy, nd h l xclll ld l nd bld l bc ly dcd Th pn n dlp dnhd cdc p, hch p hc l, lld by dh Th n qnc cn b pnd by h dnn ldn h nlccd Aldn nc d bpn nd p cn
7 n ldn, ln n hypnn nd hypl; lly hypnn lly ld bc h nly ll nc n xclll ld l ln d cp Th hypnn nd hypl xcbd by ncd d n Bc xpnn h xclll ld l nd h n l p, pl nn cy ppd Th p dpln n Cnn ynd dc h cncnn bly h dny, ldn ply, nd c cl n nd blc ll Ipd cn dnccl hn cc n Addn d Dcn h dnl cx cn l n d, bcl, cnc Th pc ld p dcn n lcccd nd nlccd ncn A l h dcd cl cn, h cpny nc n ACTH cn, hch pdc hyppnn Syp Addn d ncld h lln lc Mnlccd Dcncy Exc l d, hypl, hypnn, nd ncd pl nn cy Exc p nn nd hypl Mld cd Glcccd Dcncy Abnl cbhyd,, nd pn bl ln n cl n, n hyplyc, nd pd lzn ny L pp nd h l lnc Th nbly c ncd n cl dn ld n Addnn c 1
8 Th 8-dy pd h l xl cycl dnd by h qd h dlpn h llcl nd cp l nn nd h dbc c n h hyphl h hn hy c Mnhly n cycl; ncn h ndpc hn Th nl pdc y h l chczd by nhly hyhcl chn n h cn h l hn nd cpndn phycl chn n h nd h xl n Th hyhcl pn clld h l nhly xl cycl Th dn h cycl 8 dy I y b h 0 dy ln 45 dy n n, lhh bnl cycl lnh qnly cd h dcd ly Th ncn l h l xl cycl F, nly nl nlly ld h ch nh, h nlly nly nl ll bn Scnd, h n nd ppd n dnc plnn h lzd h qd h nh Gndpc hn nd h c n h lc 7 Th n chn h cc dn h xl cycl dpnd cplly n h ndpc hn FSH nd LH, cd by h n py lnd In h bnc h hn, h n nc, hch h c hh chldhd, hn l n py ndpc hn cd A 9 1 y, h py bn c ply FSH nd LH, hch ld n nl nhly xl cycl bnnn bn h 11 nd 15 y Th pd chn clld pby, nd h h nl cycl clld nch Dn ch nh h l xl cycl, h cyclcl nc nd dc bh FSH nd LH; h cyclcl n c cyclcl n chn Bh FSH nd LH l h n cll by cbnn h hhly pcc FSH nd LH cp n h n cll bn In n, h cd cp nc h cll cn nd lly h h nd pln h cll ll Al ll h ly c l cn h cyclc dnn nphph cnd n y n h cll cypl, hch c h n pn n nd lpl phphyln y nzy h l x hn ynh On llcl dlpn Th Fllcl h A h bnnn h nhly cycl, n llcl cp l pn
9 En nd pn cncnn n h bld h l ll A l, h hyphl c n nhby nl blc cn GnRH Th GnRH h cd l FSH nd LH cn h py, nd h FSH l dlpn py n llcl Th llcl ndd by nl cll, hch bn c ld n h cn h c; h n n xpnd ld-lld n h nd h cy A h, h c d n nl llcl Th ld ch n n, hch d n h bld nd l n p n cncnn Th llcl cnn dlp, ld by FSH, LH, nd h n cd by h llcl ln h nl cll pcd, ccpnd by h ndn ly hcl cll dd h h y Wh ccln ddnl ld nd cnnd dlpn, h llcl d cl llcl A ppxly 1 dlpn, n llcl bn h h Th nn llcl, hch dlpd h llcl, nd nd dn Th nn dnn llcl cnn dlp pdly, h pln nl nd hcl cll ld by FSH nd n Th n p dlpn ddnl FSH nd LH cp n h nl nd hcl cll, hch pd p dbc cycl pd dlpn h n llcl Bc h pdly n cncnn n n h bld, h hyphl c n nhby nl dp GnRH cn Th l n ppn FSH nd LH cn h py; h dcn n h cn FSH pn h dlpn ddnl llcl Th dnn llcl cnn dlp bc nnc p dbc cycl, h h h cl llcl nl, nd n ddnl py llcl bn dlp lc 8 Oln Oln n n h h nl 8-dy l xl cycl cc 14 dy h n nn Ab dy b ln, LH cn cc Th LH ncy ln cc
10 n d n h llcl dn h dy dly b ln Fncn En En c h nd pln h cll h l x n nd h cd h pdcn En l h h nd dlpn h nd xnl l x n A pby, h ll n pdly, cn pd h n h, llpn b,, n, nd xnl nl Th lnn h, h nd, bc hcnd nd h c n En l dlpn h b, h n xn dcl y, nd dpn n h b En n h h b nd h l-pdcn pp Thy l pnbl h chcc h nd xnl ppnc h l b H, hy d n cpl h jb cnn h b n l-pdcn n lc En c h h ln by ln blc cy pd pd h n h h bl A pby, h c n c h h ln bn, lhh p l nly y bc h 0 7 c cl h pphy h bn Lndnl n c h cc nly h pphy, nc hy cld ddnl lnhnn h bn cnn plc En h c nc l bdy pn nd blc I p dpn n h bcn, pclly n h b, hp, nd hh Fncn n Th pn ncn pn p cy chn n h n nd dn h l hl h nhly xl cycl Th pp h plnn h zy n h l c n h lnn h llpn b, cn cn h ld h pd nn h lzd dn p h Th hn l dc h xcbly nd ly h n h cl
11 40 Mcn nd lln M ncn h ch Rln Mcn nd lln M h cl chn nnd by h bnch h h cnl n, nd h chn pc cnlld by ncl n h bn Sln pcc cl n h bn cn ll c hyhcl chn n Al, ln n h hyphl, ydl, nd n h cbl cx n h ny nd ll cn n c chn Mch h chn pc cd by chn lx Th pnc bl d n h h n lx nhbn h cl cn, hch ll h l j dp Th dp n n n ch lx h j cl h ld bnd cncnth clly h j c cl h h, b l cp h bl n n h lnn h h, hch nhb h j cl nc n, lln h j dp nd bnd nh ; h pd n nd n lc Al, dnzy c nly n h Chn pn dn ll d c d pcl; h, h dn blly dpndn n h h d 8 l c xpd cn 7 Vlny lln Whn h d dy lln, lnly qzd lld ply n h phynx by p h n pd nd bcd n h pl Th phynl lln Inlny nd cn h p d hh h phynx n h ph Whn h d dy lln, lnly phd n h phynx by h n, hch cn h lny lln Th bl d l lln cp, nd pl h cp p h bn n c phynl cl cncn ll: Th pl plld pd, pnn lx d n h nl c Th plphynl ld n h d h phynx plld dlly, n l l h pd h p l bjc n h p phynx
12 4 Scn h l Cpn nd ncn h l Rln ly cn Sl cnn cn nd c cn Th cn cnn pyln (n α-yl), hch n nzy dn ch Th c cn cnn cn lbcn nd c pcn Sl cnn hh cncnn p nd bcbn n nd l cncnn d nd chld n Sly cn - pn: Th py cn h cn cnn pyln nd/ cn n ln h n nc cpn l h xclll ld Th py cn hn dd n h dc, ll: Sd n cly bbd nd p n cly cd n h dc An xc d bpn c n ch n h ly dc, cn chld n b bbd ply Bcbn n cd n h dc cd n p by xchn bcbn chld n b l by n c cy pc lc 4 8 Sln cnlld nly by pyphc n nl Thly ncl n h bn xcd by nd cl l h n, h, nd phynx Sln cn l b cd by hh cn h bn
13 nl h n nd lcl nc lx c n cll (G-cll) n h nl c c n Gn cd by bld h xync lnd, h nly l pl cll Hn Whn cylchln nd n l h pl cll h, hn cn nhnc cd cn Th hn cc ln cd cn pnn cn ld by cylchln nd c cd Gc cn nhbd by xc cd n h ch Whn h ph c jc ll bl 0, n cn dcd n: h hh cdy l h l n dl cll, hch n n dp n cn by h G-cll h cd c n nhby n lx h nhb c cn Th chn pc h ch lc 8
14 Innl d jc cd by h cyp Lbhn Th cyp Lbühn l bn h nnl ll, nd h nnl c bh cyp nd ll cd by n phl cpd cll yp Gbl cll c c hch pd l ncn lbcn nd pcn h nnl c Ency c l qn nd lcly n h cyp Thy l bb h nd lcly ln h h nd pdc dn h c h ll lc 9 8
15 49 Dn nd bpn cbhyd n h nnl c Dn Th dn cbhyd bn n h h nd ch Sl cnn h nzy pyln, hch hydlyz ch n l nd h ll ply lc ncc cn cnn l qny α-yl Th ncn pncc α-yl l dncl h h αyl n l b l pl; h, n chy p n h ddn nd x h pncc jc, lly ll h ch dd Dcchd nd ll lc ply hydlyzd ncchd by nnl phll nzy Th cll bh bd cnn nzy h pl h dcchd lc, c, nd l ll ll lc ply n h cnn ncchd Lc pl n lcl lc nd lcl lc Sc pl n lcl c nd lcl lc Ml nd h h ll lc ply ll pl n lcl lc lc 9 Abpn Enlly ll cbhyd bbd n h ncchd Th bndn h bbd ncchd lc Glc npd by d c-np chn Ac np d hh h bll bn n h pclll pc dpl h d nd h cll Th dc c d hh h bh bd h ncy n by cndy c c-np Th d cbn h np pn h q nh bnc, ch lc, bnd lnly Whn nnl lc cbn h h np pn, d nd lc npd n h cll h
16 Th pn l pydxn h cnzy n h nnn pc h ynh n cd Acbc cd (Vn C) c h nzy plyl hydxyl, hch p h hydxyln p n h n hydxypln, n nl cpnn clln nl h h nd nh clln b n bcn, cl, bn, nd h Vn D Inc clc bpn h nnl c nd hlp cnl clc dpn n bn Vn E n xdn nd Vn K cy n cln c Mnl bl lc 7 9 Mn qd cly ny nclll nzyc cn Clc pn n h bdy nly n h clc phph n h bn hph h j nn xclll ld hph h h bly cbn bly h ny h cnzy y ncy pn h blc pc In ncn n h bdy c xyn nd n lcn ccp; blly nl bh h np xyn nd h pn xd y n cll Idn pn h n nd ncn hyd hn Znc n pn cpnn cbnc nhyd, h nzy pnbl h pd cbnn cbn dxd nd n h bld, nnl c, nd dny bl Znc l cpnn lcc dhydn, hch pn h ncnn pyc cd nd lcc cd Fln ncn pn h dcy Dy blnc Eny lbl n d Eny n nd p blncd nd dy- cndn
17 55 Bdy p H pdcn nd h l Sn nd ln Rln bdy p l h hyphl Bdy p Bdy p cnlld by h blnc bn h pdcn nd h l H pdcn bypdc bl Ex h cn b nd by cl cncn n h h by n nc n hyxn n h ln Th h l dnd by h h cndcn h n nd h h cndcn h n h ndn Bld l h n h bdy c pd h n Bld l dbd ply dly ndnh h n An nc n bld l h l c h l, nd dc n bld l h l c l h l Th n hhly c h d y nn h h bdy c h n lc Rdn c l h n h nd y 5hnh h ndn, h bdy I hbdy p 0 h h ndn 1 d bdy p l hn h h ndn, Cnly, h H pdcn nd h l h ndn d h h bdy Cndc h l cc by dc cnc h n bjc Cnc h l l n Th nx h n c d by cndcn Whn h d, h n cndc h h n ly nd Cnc h l h chn h cln c nd Epn ncy chn h l y hh p Ep h l y pn hn h nnnl p n bdy p Ep h l bc h nly y cl h bdy hn nnnl p hh A n c h n nc h pn nd l nc h cn p h l Sn nd ln
18 S lnd nnd by yphc chlnc b Whn lnd ld, h pc ln cn ncd Th bpn lcly cc cnn I l l pc ln cd nd h lcly bpn n cnn, lcly l n h Th n chn cn dp nnnl nd Exp h cl c n nc n h x pdcn Th l n nc h p h l nd hlp nn nl bdy p Acd h n nc n h pdcn dc n h d chld cnn h ; h ll b cnn bdy l Th dcln n h d chld cnn h ply h l ncd cn ldn, hch nhnc d bpn h dcl pn h lnd lc Rln bdy p - l h hyphl 0 1 Th bdy nn ccl c p 71 C Whn bdy p nc b h ll, h-ln chn nd Whn bdy p ll bl h ll, h-nn chn nd Th ccl p clld h pn h p cnl y Tp dcn chn Th pn chn d cl h bdy: Vdln h bld l h n cn nc h n h n h n Sn nc h p h l Sn nhbn chn h nc h pdcn plc, ch hn nd chcl hn Tp ncn chn Whn h bdy cld, h p cnl y n chn dc h l nd nc h pdcn:
19 Ac np hh h cll bn - py nd cndy c np Inn by h cll - ndcy Tnp hh clll h Ac np hh h cll bn - py nd cndy c np Ac np n n bnc c h bn n cbnn h c pn b l n n lcchcl dn Th pc q c ny n ddn nc ny Whn h dnc n cncnn h bnc b npd ll, h np ppxly n ppn nc n cncnn A hh cncnn, h np ld by h hch h chcl cn bndn, l, nd c cnnl chn cn cc y c np Th ny dd dcly h bdn AT h hh-ny phph cpnd Th d- p (+-K+) pp np d n cll nd p n n cll Th d n bnd c pn n h nd h cll, nd p n bnd h c pn n h d h cll Th c pn h AT cy, nd h ln bndn d nd p n c h AT ncn h pn bc cd Th hn cl n lcl AT, pln AD nd lbn hh-ny phph bnd ny Th ny hn c cnnl chn n h pn c lcl, xdn h d n h d nd h p n h nd Scndy c np Th ny dd cndly ny h h bn d n h nc cncnn dnc bn h d bn, nlly cd by py c np Th d lcchcl dn d cndy c np pc C-np Th dn ny d cn pll h bnc ln h h d hh h cll bn n pcl c pn Cn-np Th d n nd bnc b cnnpd pp d h bn, h d ly n h cll n A pn c qd lc Inn by h cll - ndcy
20 Rhyhcy cn xcbl Spcl pc nl nn n n n Thhld xcn, c lcl pnl Rhyhcy cn xcbl Rp l-ndcd dch cc nlly n h h, n h cl, nd n ny h nn h cnl n y Th hyhcl dch c h hyhcl b h h, hyhcl pl h nn, nd ch nnl n h hyhcl cnl bhn R-xcn pc ncy pnn hyhcy F pnn hyhcy cc, h bn n nl b pbl nh d n ll c bn dplzn Th n bn pnl n h hyhcl cnl cn h h nly 0 70 lll Th n nh n l p h d nd clc chnnl lly cldth, h lln qnc cc: d nd clc n l nd h nc h bn l n h p dcn, hch h nc bn pbly ll n l nd h pbly nc, nd n, nl n cn pnl nd Thn, h nd h cn pnl, h bn plz A nh dly llcnd, pnn xcbly c dplzn n, nd n cn pnl cc pnnly Th cycl cnn nd nd c l-ndcd hyhcl xcn h xcbl lc 0 1 Spcl pc nl nn n n n L n b ylnd nd h ll n nylnd Th cnl c h b h xn, nd h bn h xn d cndcn h cn pnl Sndn h l xn hc yln hh dpd by Schnn cll Th hh cn lpl ly clll bn cnnn h lpd bnc phnyln, hch n xclln nl A h jnc bn cc Schnn cll, ll nn nld nly μ n lnh n h n cn ll l
21 h bn h xclll ld nd h xn Th h nd Rn Sly cndcn cc n ylnd b En hh n cnn l ncnly hh h hc hh ylnd n, hy cn l h cndbl hh h nd Rn Th h n pl jp nd nd ln h b, hch h n h ly Sly cndcn l n: Incd lcy F, by cn h dplzn pc jp ln nl ln h x h n b, h chn nc h lcy n nn n ylnd b Eny cnn Sly cndcn cn ny h xn bc nly h nd dplz, lln ll l n hn ld h b ncy nd h qn ll ny -blhn h d nd p cncnn dnc c h bn n pl Cndcn lcy I n l, ylnd n b Th lcy nc ppxly h h b d n ylnd n b nd ppxly h h q h b d n nylnd b lc 1 1 Thhld xcn, c pnl A n lccl l y n b bl xc b H, hn h l h l ncd, h c pn hch xcn d plc
22 n nbl h cbnd xcy pynpc pnl (ES) xcd hhld Th pd nlx ply chd d n h n nlz p h ny h n bn pnl Th, h n bn pnl h ncd n h p dcn Th p nc n l b h nl n nnl pnl clld h xcy pynpc pnl ( ES), bc h pnl hh nh n h p dcn, ll lc n cn pnl n h pynpc nn, h xcn Opnn p chnnl ll ll ply chd p n h x, nd h ll l h n bn pnl n hn l Th, bh chld nlx nd p lx nc h d nclll ny, hch clld hypplznth nhb h nn bc h bn pnl n n hn h nl nclll pnl Th, n nc n ny bynd h nl n bn pnl ll clld n nhby pynpc pnl (IS) lc 4 1
23 cd nd h hyphl Snn c n nhb pn phy n h cd, nd n nhb cn n h hh n h n y hlp cnl h d h pn, php n c lp ppd Th nppd n nly dn cl n h ynhzd dnly nd h cn lly l nd n h y q dn h h ll-lcl n Thy ynhzd nl p l-pn lcl by b n h nnl cll bdy Th pn lcl hn n h pc nd h ndplc cl h cll bdy nd bqnly nd h Gl pp, h chn cc: h nppd-n pn nzyclly pl n ll n, hch h h nppd l pc h Gl pp pc h nppd n n n cl h ld n h cypl Thn h n cl npd ll h y h p h n b by xnl n h xn cypl Fnlly, h cl l h n h nnl nl n pn cn pnl Thy n c ch plnd cn S h cn ncld plnd cl clc chnnl, plnd chn n h blc chny cll, plnd chn n cn dcn pcc n n h cll ncl, nd/ plnd ln n nb xcy nhby cp lc 1
24 9 hylc ny ll cl Gnl chn nd lcl chn cl cncn cl jncn Mcl cn pnl M n Excn - cncn cpln hylc ny ll cl Mybl cpd cn nd yn ln Ech cl b cnn hndd hnd ybl, yn ln nd cn ln l d by d Th ln l plyzd pn lcl h pnbl cl cncn Lh nd d bnd Th yn nd cn ln plly nd nd h c h ybl h ln lh nd d bnd Th lh bnd cnn nly cn ln nd clld I bnd Th d bnd clld A bnd cnn yn ln ll h nd h cn ln Th lnh h A bnd h lnh h yn ln C-bd Th ll pjcn h d h yn ln c-bd Thy pd h c h yn ln ln n lnh xcp n h cn Myn cbd nc h cn ln cn cncn Z dc Th nd h cn ln chd Z dc Th Z dc p c h ybl nd n nh, chn nd lnn h ybl c h cl b lc 7 1 Gnl lcl cl chn nd chn cncn Gnl chn
25 Oxyn ld n h ld n h dld lcl xyn h hn nc xyn In bl In pn h n hlbn, ylbn, nd h bnc, ch h cych, cych xd, pxd, nd cl Th l qny n n h bdy b 4 5 In npd nd d Whn n bbd h ll nn dly cbn h βlbln clld pnn, nn, hch npd n h pl Th n lly bnd Exc n n h bld dpd n l hpcy nd n clndhll cll h bn Onc nd h cll' cypl, n cbn h h pn pn n Whn h qny n n h pl dc l hn nl, n d n q ly nd npd by nn n h pl h pn h bdy h ndd A nq chcc h nn lcl bly bnd nly h cp n h cll bn h yhbl nd bn Tnn nd ndcy n h yhbl ln h h bnd n Tnn dl h n dcly h chnd, h h ynhzd Whn d bld cll h chd h nd h l pn nd dyd, h hlbn ld nd by cll h ncy-cph y Th n h lbd cn b d n h n pl d n hlbn lc 0 4 1
26 7 Gnl dn h n y Mj ll cnl n y ncn Gnl dn h n y Th n y ncld bh ny (np) nd (p) y ncnncd by cplx n chn Th ndnl n pn h nn, hch ypclly cn cll bdy (), l dnd, nd nl xn Mch h cy n h n y chn h l ny cp lcd h dl nn ny nn Snl l pphl n ch h pnl cd nd hn nd hh h bn Incn ny pcd nd nd h nn d n pl nn ch h h ln nl cn b d n n ppp pn lc Th dn h n y pnbl cnlln y bdly c ch cncn d nd h cl nd cn by xcn nd ndcn lnd Only lly ll ppn h ny np cd by h bn d n n d pn Mch dcdd ln h ncn hnd Sny np cn b d n h y y ncn 1 Mj ll cnl n 5 1 n y h nhd pcl ncnl cpbl ch Th hn hn lny dlpn Th j ll h cnl n y h pcc ncnl chcc: h pnl cd ll En h pnl cd h bn c n h hh nc n, ny hhly nzd pnl cd ncn ll cc F nnc, nnl cc n h cd cn c ln n, lx h hd pn h bdy pnl bjc, lx h n h l pp h bdy n y, nd lx h cnl lcl bld l, nnl n, ny xcn Th pp ll h n y n p n by ndn nl dcly h pphy h bdy b by ndn nl h cnl cn h cd, ply cndn h cd cn p h ncn h l bn bccl ll
27 74 hylc ny h nn Tnn nd pcn nl n nnl pl nl cc Inbly nd bly nnl cc Cbpnl ld hylc ny h nn lc n nddl Any nn, ch h cbl cx, hl, d nnl pl Ech nnl pl h ncl n h hl, cn b 5 1 l np (n), cp ld, nd n l hch pjc nzd n xn Tnn nd pcn nl n nnl pl An y cn pd h hhld bhhld ln h nnl pl Thhld ln nc h bn pnl b n ll n l cll, nd hy n cn pnl In h, h bn pnl y b lhly dplzd b n q nh ch hhld (bhhld) Th cll d b cld; h, hy xcbl bc ll xcy pynpc pnl (ES) hn nl bn h cll hhld nd cn pnl In nnl pl, dnc ncn nl cn
28 7 Sc nn Gnl nn Th cl nd pn n Sny phy nn c nl n h cnl n y Sc ny cx Sc nn Gnl nn Clcn Mchncpn ncld bh cl nd pn nn Thcpn dc nc dc n p ccpn dc d h l pcc pn-dn lcl Th ny dl cnyd h c ny y ncld dcn (pcly lclzd) ch, cd (ply lclzd) ch, p, bn, nd h n c bdy pn nd bdy n, hch cllcly d ppcpn Excp nn h h n ln bdy c c, ch h n nd bcn, ll dp c ncldn cl, c, nd ndn Sny nl h nnl n (nddl dd c) clld cl nn lc 9 Th cl nd pn n 5 1 n cld p nd dnc nn, Tch, p, nd bn hy ch dcd by h nl cl cl cp: Th chncp A l x yp chncp cld cl cp: F n ndn nd n yn dny n ll h n ll h cn h y Mn' cpcl n ncpld, pdly dpn cp nd n h nn hy n ch h np nd lp, h pclly n n h lh ch ln Ml' dc nd n lb n b l pn n d nb n hy n c Th cp lly lly dpn nd hh nl cnn ch bjc n h n H nd n nnd b h b ch h n h bdy c Thy pdly dpn nd dc n bjc h n c h dplc h h Rn' nd-n ncpld ndn lcd n h n nd dp, ll jn cpl Thy xhb ll dpn nd h nl
29 nd h b h cl, nd h chnnl cpbl cndcn l nb p n Th, p n p n h cll h ndn ndlyphc ld, cn cp bn dplzn Cnly, bndn h pl cl n h pp dcn (bcd h ncl) dc h nn n h chn; h cl h n chnnl, h cn cp hypplzn Whn h cl bn d h ncl, h pl c nc; cnly, bndn h cl y h ncl dc h pl c, n nn cplly Th, h nn h hd n pc chn nd h h h cn bnd h cl, ppp nl nd h bn cnl qlb In ch cl, ch h h cll nd n dn dcn h h h cll ld hn h hd bnd d, ld hn bnd bcd, h ld hn bnd n d, nd h Th, dn pn xcn cc n h cl n b ch nn h hd n h nl ld I h pn h pp h bn h hd nn n pc lc Sccl dc bl pp, nn h 0 7 Th h ccl dc n ch 1 (hznl) ccl dc, nd n, p, nd ll h nl n nh h hy pn ll h pln n pc Ech ccl dc h n nln n nd clld h pll, nd h dc nd pll lld h ld clld ndlyph Fl h ld hh n h dc nd hh pll xc h ny n h pll n h lln nn: In ch pll ll c clld c pll On p h c l ln, h cpl Whn pn hd bn n ny dcn, h n h ld n n h ccl dc c h ld n ny hl h ccl dc h h hd Th c ld l h dc nd hh h pll, bndn h cpl n d Rn h hd n h pp dcn c h cpl bnd h pp d
30 Th blc pn lnn n h pn ly dc lh lcn hh h lb h y Th pnc h pn b lld by bnc n lbn nddl Bc h l n lcn nd h lb h y, lbn ly xhb b hn 0/100 l cy Th pn ly l l qn n A d n h ynh l pn l ncn hcp cn d nd cn n nd nn n n h phcp ly, cll bdy n h ncl ly, nd ynpc nl n h plx ly Hznl cll, bpl cll, nd cn cll c ynpc np n h plx ly, h h n h nn ncl ly, nd pynpc cnc n h nn plx ly Gnln cll c ynpc np n h nn plx ly, h n h nln cll ly, nd xn h c hn h pc n b ly Inplx cll n nl n h pp dcn h nn plx h plx ly lc In h, h phy cll lly dc nd cn cn nln nl cp, bpl cll, nd 1 nln 8 cll Hznl cll cn b nld n h plx ly, h cn cll c n h nn plx ly M pphlly n h n, h d phcp bndn, h np l phcp cn cn n nl bpl nn, hch y h p nly n cn cll h hn pjc nln cll Th pn h p d n phy Hznl nd cn cll cn pd ll cnncy n pn n h n ncld l (d by d nd cn) nd -nbyc cd (GABA), lycn, dpn, cylchln, nd ndln (d by cn cll) Th n d by hznl, bpl, nplx cll ncl Bnnn h h phcp, nn nl p h nln cll ly cc nly by lcnc cndcn (dd pnl) nd n cn pnl Th nln cll h nly nl nn cpbl nn n cn pnl; h n h nl n h n ccly lc llnn nny, nd nl nn lxbly n h pn chcc Vl hy Axn nl nln cll h pc n Axn h n h nl n c h pc ch, nd h h pl n p hh h
31 Cnly, nl phy, V-1 n djcn V-, nd pl cn cx cy h X cll nn ncy nly l dl Th nl d cnz x, l, nd d ln h h cl bjc; hy h dn h h bjc nd nn lc 5 8 1
32 dync, h h dbn ncl chn b c Sln dync nn nhnc nly h dync pn, nd c nn ln nhnc h c pn Mcl pndl xhb cnn bcnd ll cy h cn b dld pd (ncd n) dnd (dcd n) ncy h nn cl cy Spnl lx - yc, lx nd hdl In h pnl dcb nl, l ny yp cn ny l lb lly c h lx cl h lb cnc, hby hdn h lb h ln bjc Th clld h lx lx Th lx lx lcd plly by ln pn ndn, ch by pnpc, h, nd, hch n l clld nccp lx, ply pn lx Sln ch cp cn l lc nd l plnd lx lx I p h bdy h hn n h lb pnlly ld, h p ll lly b hdn h l, b h lx y n b cnnd lx cl, n hh bclly h yp lx Th, h ny pn h lx n h dn h bdy clld hdl lx lc nl chn h lx lx 5 A pnl l ppld 1 h9 hnd; l, h lx cl h pp bc xcd, h hdn h hnd h pnl l Th phy lcn h lx lx d n p dcly h n nn b nd p n h pnl cd nnn pl nn nd nly cndly h nn Th h pbl cc h- -nn phy; h, h nl h lx ny nn nd nl h lln bc yp cc: dn cc pd h lx h ncy cl hdl; cc nhb h nn cl, clld cpcl nhbn cc; nd cc c dch ln ny cn cnd h l Whn llcnd pn n bn b ld, h lx pn pp Thn, n h nx cnd, h lx bn, hch chcc nlly ll cplx n lx h pnl cd Fnlly, h l, h cncn h cl n d h bln, b bc dch, ny llcnd h cc Th dch h cc n h lx lx l cnly l bh yp p dch cc lnd dch cc
33 88Th bl nl nd h ncn D h bl nl Th bl nl cn nh ccy y h ncn lly n by l b n cl cn h h cbl cx nd ccpnl cnl y In c, h bl nl c h np nl h cbl cx l nd l n l ll h p nl bc h cx On ch d h bn, h nl cn h cd ncl, pn, lb plld, bn n, nd bhlc ncl Thy lcd nly ll nd ndn h hl, ccpyn l pn h n n bh cbl hph Al ll nd ny n b cnncn h cbl cx nd pnl cd p hh h pc h l bn h j h bl nl, h cd ncl nd h pn Th pc clld h nnl cpl h bn I pn bc h n cn bn h bl nl nd h ccpnl y cnl Fncn h bl nl n xcn pn cy Th pn cc c Th cc h ncnnc h c cpn hl bl nl nc n ply lnd nd xly cplx In nl, ncn hnl n h p nd h pn h hn h cd ncl Snl nd pplny cx nd nd hn n h lb plld h pn h nnlndxnl 0 bdn h ynpclly lnd Th l c dn lcn Th xnl n cpclly n nh b l pjc lnd h h bhlc ncl, nd h nnl n pjc h hl nd bn n M ncl n h hl h c plldl np pjc bc p nd py n h cx Th cnncn lp h ln cx pn h pn nd lb plld Th cll pjc, n n, ncl h hl h n nl bc h cx Whn ch lp h cc, h -clld dc nd ndc phy Th dc phy ld nhby nn n h pn cll n h nnl plldl n, hch hn pjc hlc ncl Th nn n h nnl n n nhby plldhlc cc nln hlccl nn h pjc h cx Th nd l h h hlccl nn dnhbd, nd h ll h nn xcy np hl cx I d h h dc phy nhnc n Cnly, h ndc phy nl nhby nl nd hh h pn nd xnl plldl n h nlly l n h
34 9Th nc n y- bc chcc yphc nd pyphc ncn Fncn h dnl dll Al pn h yphc n y Th nc n y h pn h n y h cnl h cl ncn h bdy Th y c pdly cnl l p, nnl ly nd cn, ny bldd pyn, n, bdy p, nd ny h c Gnl nn AS Th cnl pn h nc n y lcd n h hyphl, bn, nd pnl cd Hh bn cn, ch h lbc cx nd pn h cbl cx, cn nlnc h cy h nc n y by ndn nl h hyphl nd l bn Th nc n y l n p hh cl lx Th, bcnc ny nl cl n cn n h nc nl, h bn, h hyphl nd hn n bcnc lx pn dcly bc h cl n cnl c Th n nc nl nd h n h bdy hh j bdn clld h yphc n y nd h pyphc n y Th nc n y y h cl n, bld l, nd cy lnd Th cll bdy h pnlnc nn lcd n h h bn h pnl cd Th xn h cl nn pjc hnly ylnd pnlnc b n nc nln Th pnlnc nn h cll bdy n h nl nd nd n nylnd xn, h pnlnc b, cl c cll In nl, yphc nl lcd cl h cnl n y, h pyphc nl lcd cl h c Syphc phy h h pnlnc b nd ln pnlnc b, h pyphc phy h ln pnlnc b nd h pnlnc b lc 1 Bc chcc yphc nd pyphc ncn
35 β-dnc cp pnphn xc nly α-cp, lhh xc β-cp l xn Epnphn xc bh yp cp ppxly qlly Th l c npnphn nd pnphn n c n dnd by h yp cp lcd n h n Th ln α-cp l n cncn, dln h, cncn h nnl nd bldd phnc, nd cncn h pl cl Th β-cp bddd n β1, β, nd β cp byp Sln β1-cp c n nc n h nd nh cncn Sln β -cp c ll cl dln, bnchdln, n lxn, cln, nd lycnly Sln β -cp ndc lply n dp nd h cnn ny n lpd n h (hn) lc 4 1 Fncn h dnl dll Sln h yphc n h dnl dll c l qn pnphn nd npnphn b ld n h ccln bld Ab 80% h cn h dnl dll pnphn, nd b 0% npnphn Th c h pnphn nd npnphn ld h dnl dll l 5 10 ln hn hn hy ld by yphc nn bc h hn lly d h bld Th ccln npnphn c cncn, ncd h nd cncly, nhbn h nnl c, nd dld ppl Th ccln pnphn, bc bly nly l h β cp, h c n cdc pnc hn d npnphn Epnphn c nly cncn h bld l n cl, ln n lh nc n l p b
36 h hyphl h bn cl n Th bndl c b n bh dcn, n n ln cncn y Bhl ncn h hyphl nd cd lbc c Ec cd by ln In ddn h nd ndcn ncn h hyphl, ln ln n h hyphl n h pnd c n nl bh nl nd hn bn In nl, h bhl c ln h lln: Sln n h ll hyphl n nly c h nd n, b l nc h nl ll cy h nl, ldn nd hn, dcd bqnly Sln n h ndl ncl nd ndn nly c c pp h cd by ll hyphlc ln h, n y, dcd n, nd nqly Sln hn zn pncl ncl, lcd dly djcn h hd ncl ( l ln h cnl y h ncphln h cnn h h pn h hyphl), lly ld nd pnhn cn Sxl d cn b ld l h hyphl, pclly h n nd p pn h hyphl lc 8 1 Ec Cd by Hyphlc Ln n nl, c c pp h cd by Ln n h hyphl, ln F nnc: Bll ln n h ll hyphl ll dc dnn nd n l z, n ldn lhl n Th ln c x py h nl ll, h l d Bll ln h ndl h hyphl c c h nly pp h cd by ln h ll hyphl: xc dnn nd n ll hypcy nd n cnn y ln h qn b x n h lh pcn Sln ln n h n h lbc y, pclly n h ydl, h pl, nd n h ncphln, n c c l h lcd h hyphl Fncn h hppcp nd h ydl Hppcp
37 97 Th cdcl y n xc Mcl bld l nd cdc p dn xc Th bld l hh cl nc p 5 h nl dn xc M h cl bld l cc bn cncn bc h bld l cpd dn h cncl pc An nc n l p dn xc dcly nc l Schn h l ll by h nc n p dc cl nc nd nc l ch Th cl cncl pc l ply dc cl bld l bc h cncn ll cl cp h ncl bld l; h, n nc cl cncn cn c pd cl bc lc dly nh xyn nd h nn dn h cnn cncn Ahlc nn nc l nd dc n h I nl pn xn hlc nn h bc yp, bh h h z nd x cdc p nc Th l h nc, nd h n h dc lc 4 Th h l h n xc n cn p Dn x xc cdc p 90% x l, b plny nln nly 5% x Th cdcl y lly l h n xc h cn b pd Dn ny yp cdc d, h x cdc p dc, hch l h n xc h cn b pd Any yp py d h ly l plny nln xyn-dn cpcy l l xc
38 99Bdy h pdcn, ld nd l n xc Bdy h pdcn Al ll h ny ld by h bdy bl nn nlly cnd n bdy h Th xyn cnpn by h bdy cn nc ch 0-ld n h llnd hl nd h h n h lbd n h bdy l xcly ppnl h xyn cnpn, n qcly lz h nd n h njcd n h nnl bdy hn pn ndnc hlc n x, h h l n h bdy, n y h nd hd dy h h n chn cnn ln h h, n nlbl nd n lhl cndn clld h cn ly dlp n h hl H Dn ndnc hlc, n nd nl nnnl cndn, h bdy p n nl ll 7 C 40 C Wh y h nd hd cndn xc clhn, h bdy p cn ly 41 C 4 C A h ll, h ld p l bc dc cll, pclly h bn cll Whn h hppn, lpl yp bn pp, ncldn x n, xhn, hdch, dzzn, n, p n, cnn, n, cllp, nd ncncn Th hl cplx clld h, nd l dly cn ld dh In c, n hh h pn h ppd xcn, h p d n ly dc by l On h n h h h hh p, h p-ln chn l n l A cnd n h n h, h y hh bdy p l ppxly dbl h ll nclll chcl cn, h lbn ll h Th n h dc h bdy p pdly pbl Th pccl y d h ll clhn, nn py cl n ll c h bdy cnnlly pn h bdy, nd bl h bdy h n lc Bdy ld nd l n xc
39 nd I xl n cncnn bly 100 O/L, h nl l n h b xcd, clld h bly n l, cn b clcld Th nl l l n h n cnb dhydn, ln h l h n, py c, nd nnl c, hn n lbl dn Mcn Th cn lx nl pl lln h ny bldd h cl n h pnl cd nd h cl n bc h bldd I cdnd by nn n h pnl cd nd cn b nlncd by nl h bn Whn h ny bldd bc chd h n nc n h qncy cn pnl cd h bldd ll h cl n In pn, pyphc nn h pnl cd h bldd cd, nd h c h h cl n h bldd ll cnc Th ny nl h cl n l l cndn phy h pn nd cb, hch l n cnc d n I nn n cnnn h, h bn nd pl dn h pnl cd nhb h cn lx Ipl cd c nn p h xnl ny phnc cncd, hch l pn nn Whn nn dd, nl h bn l h cn lx Th bn l dc cn pnl n h c nn lx h xnl ny phnc lc 9
40 Rpn Mchnc plny nln Th py y ppl xyn h nd cbn dxd Th j ncnl n pn ncld: plny nln,hch h n n nd h ll dn xyn nd cbn dxd bn h bld nd ll np xyn nd cbn dxd nd h pphl ln pn l q bhn ccplhd h h dph Dn npn, cncn h dph pll h l c h ln dnd Dn xpn, h dph lx, nd h lc cl h ln, ch ll, nd bdnl c cp h ln Dn hy bhn, h lc c n cnly pl c pd xpn Th x c chd nly hh cncn h bdnl cl, hch ph h bdnl cnn pd n h dph c Mcl h h b c cl npnlcncn h xnl ncl c h b pd nd d n bc hndl n ncldn h nnl Mcl h dp h bc cl xpn, c Oh4bdnl cl cp h bdnl 8 ncl nd h bdnl cnn pd d h dph ll p h p h ld n h pc bn h ln pl nd ch ll pl Whn h l pn nd h n n, h p n ll p h py ql h phc p, hch cndd b 0 c Dn npn, h p n h ll dc b 1 c, hch cn b 05 L n h ln hn h cnd qd npn Dn xpn, pp chn cc: Th ll p b +1 c, hch c h 05 L npd h ln dn h cnd xpn Th c lnn h ll p cnc h lcl pll d n nh Th p c h ll, cn h ll
41 Cplly d Th d h plny cpll b 5 ; h d bld cll bn lly ch h cplly ll Th dnn c h pdly p hh h py bn: ncld h lln: Thcn py bn Th dn hh h bn nly ppnl h bn hcn Sc py bn In h pnc phy, ny h ll clc, h dln ll ll; h n c h l c dc by ch ld Dn ccn Th dn ccn h n ch hh h py bn dpnd n lbly n h bn nd, nly, n h q lcl h dnc c h py bn Th dnc bn h pl p n h ll nd h n h bld dcly ppnl h n hh h bn n h dcn lc 1 5 Dn Cpcy bn xchn bn h ll nd h Th bly h py plny bld cn b xpd n qn by dn cpcy; h dnd h l h d hh h bn ch n 1 H dnc n p Dn xc, xynn h bld ncd n nly by ll nln b l by cpcy h py bn nn xyn n h bld Dn n xc, h dn cpcy xyn cn nc b 5 L/n/ H, hch h h dn cpcy dn n cndn Th nc cd by h lln: Incd c Opnn p cld plny cpll nd dln pn cpll nc h c dn xyn
42 5 Up xyn by h plny bld Tnp xyn n h bld Oxyn-hlbn dcn c Up xyn by h plny bld Th O nc ql h ll by h h bld h d n hd h dnc hh h cplly, bcn l 104 H Th plny cplly bld bc l lly d h xyn n dn n xc Rn: Incd dn cpcy Th dn cpcy xyn nc l hld dn xc bc ncd cplly c nd pd nln-pn n h pp p h ln Tn y c Bld bc l lly d h xyn dn n hh h n hd h plny cplly bd, h ll n cn ll cc dn l nc n cdc p lc 5 Ab % h bld h n h l h pd dcly h hh h bnchl ccln Th bld l pn hn l bc hnd p h xchn nd O l ypcl n bld Th bld hn x h xynd bld h ln; h xn h bld clld n dx bld T n c cn c h O: R bld l I h bld l hh pcl bc ncd, qn xyn npd n h dn n pd, nd h O bc cpndnly ncd R bl I h cll xyn bl hn nl, h nl ld O nd b dcd Tnp xyn n h bld
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