let s co create Metathesis does it better, Umicore does it best

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1 let s co create Metathesis does it better, Umicore does it best

2 et s work together to create ground-breaking chemistry.

3 With the goal to offer you the most comprehensive catalyst portfolio, we have acquired Materia s unique metathesis proprietary technology, developed by Chemistry obel Prize aureate Professor Robert H. Grubbs and his team. ur metathesis catalysts deliver highly selective carbon-carbon bonds, with high yields and minimal waste, for more precise and efficient reactions. We support your metathesis needs from research through to commercial scale, offering the very best in R&D, IP security, global manufacturing and security of supply. We will continue to focus on innovation to allow you to develop more efficient, cost-effective and sustainable chemistry. et s co-create. ow including Grubbs Catalysts Easy access to a secure & comprehensive IP portfolio eading edge homogeneous catalysts Technology expertise & support of top tier universities Global manufacturing capabilities & market presence

4 A selection of Catalysts M1 series thenium Metathesis Grubbs Catalysts 1st Generation M1 igand Trade ame Chemical Formula CAS umber PCy 3 Catalyst M1 (PCy 3 ) 2 (Ind) M1a PCy 3 Catalyst M1a (C823) (PCy 3 ) 2 (benzylidene) M1b PCy 3 Catalyst M1b (C801) (PCy 3 ) 2 (butenylidene) M2 series thenium Metathesis Grubbs Catalysts 2nd Generation M2 + M20 + M22 igand 1 igand 2 Trade ame Chemical Formula CAS umber 2 1 PCy 3 Catalyst M2 ()(PCy 3 )(Ind) M2a P 3 Catalyst M20 ()(P 3 )(Ind) M2b P( ) 3 Catalyst M22 SIPr P 3 PCy 3 - PCy 3 - Catalyst M20 SIPr Catalyst M2a (C848) Catalyst M2b (C827) ()(P( ) 3 )(Ind) (SIPr)(P 3 )(Ind) ()(PCy 3 )(benzylidene) ()(PCy 3 )(butenylidene) M3 series thenium Metathesis Grubbs Catalysts 2nd Generation ( ligands) M igand 1 igand 2 Trade ame Chemical Formula CAS umber py Catalyst M31 ()(py)(ind) M31a SIPr py py py Catalyst M31 SIPr Catalyst M31a (C727) (SIPr)(py)(Ind) ()(py) 2 (benzylidene) Please visit our website to find a comprehensive list of Catalysts

5 M7 series thenium Metathesis Hoveyda-Grubbs Catalysts 1st/2nd Generation M70 R igand Trade ame CAS umber - - PCy 3 Catalyst M70 (C601) H(C)CF 4 Catalyst M SIPr H(C)CF 3 Catalyst M71 SIPr M71 + M72 + M73 SIPr H(C) t Bu H(C) t Bu Catalyst M73 Catalyst M73 SIPr R SIPr H H Catalyst M72 (C627) Catalyst M72 SIPr (C711) SI(o-Tol) H Catalyst M72 SI(o-Tol) (C571) M8 series Bis- thenium Metathesis Grubbs Catalysts 2nd Generation M80 Trade ame Chemical Formula CAS umber Catalyst M80 (C975-bis) () 2 (Ind) M80a Catalyst M80a (C875-bis) () 2 (benzylidene) M80b 1 2 Catalyst M80b (C853-bis) () 2 (butenylidene) 2 MZ1c MZ series Z-selective thenium Metathesis Grubbs Catalysts 2nd Generation Trade ame CAS umber Catalyst MZ1c (C633) MZ2c Catalyst MZ2c (C675) egend SI(o-Tol) SIPr

6 We understand the rapidly changing needs of our clients throughout the world, & provide: Innovative, metal-based chemistry Collaborative R&D Process development and scale up Commercial-scale manufacturing Supply chain expertise all with the intent of enabling current & future technologies. We offer an integrated long-term collaborative partnership approach to research, development & commercial manufacturing Makes innovation possible ffers customers continued support throughout the product s life cycle Electronics armaceuticals Highly Potent APIs Homogeneous Catalysts Platinum Group Metal Blacks Electronic Materials Exclusive Metal based Chemical Solutions Fuel Cell Catalysts Platinum Group Metal Solutions Automobile Precursors for Heterogeneous Catalysts Chemicals

7

8 For inquiries and additional information please contact Umicore AG & Co. KG Rodenbacher Chaussee Hanau-Wolfgang Germany Tel.: +49 (6181) Fax: +49 (6181) chemistry@umicore.com

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