MOLECULAR MAPS AND MARKERS FOR DIPLOID ROSES
|
|
|
- Josephine Gaines
- 5 years ago
- Views:
Transcription
1 MOLECULAR MAPS AND MARKERS FOR DIPLOID ROSES Patricia E Klein, Mandy Yan, Ellen Young, Jeekin Lau, Stella Kang, Natalie Patterson, Natalie Anderson and David Byrne Department of Horticultural Sciences, Texas A&M University, College Station, TX 77843
2 A HIGH-DENSITY SNP-BASED CONSENSUS MAP FOR DIPLOID ROSES JoinMap 4.1
3 A HIGH-DENSITY SNP-BASED CONSENSUS MAP FOR DIPLOID ROSES Fluorescence anchor SSRs (Spiller et al.)
4 Optimization of the GBS protocol and alignment results Enzyme DNA extraction method % reads mapped to strawberry genome (more complete and the chromosome order is known) Fsel CTAB+Zymo PCR inhibitor 35-36% Fastprep 36-37% NgoMIV CTAB+Zymo PCR inhibitor 54-57% Fastprep 59-60% Nhel Fastprep+Zymo clean&con % More reads from NgoMIV were mapped compared with the other two enzymes. NgoMIV (G^CCGGC) is a methylation-sensitive enzyme and there are 16,326 predicted NgoMIV sites in the F. vesca genome.
5 Mapping using JoinMap 4.1 CP: cross pollination population LOD 8 Seven linkage groups Maximum likelihood mapping algorithm
6 Use of Graphical Genotyping to Aid in Marker Order
7 Initial Rose Populations Developed Female Male Population size J14-3 (R) LC (S) 69 J14-3 (R) RF (S) 124 J14-3 (R) SC (S) 58 J14-3 (R) VS (S) 83 J3-3 (R) RF (S) 19 J4-6 (R) RF (S) 62 M4-4 (R) SC (S) 10 M4-4 (R) VS (S) 5 OB (MS) J3-6 (R) 93 OB (MS) M4-4 (R) 10 OB (MS) RF (S) 82 SC (S) J14-3 (R) 24 SC (S) J4-6 (R) 10 SC (S) M4-4 (R) 53 VS (S) J14-3 (R) Colors White Grey Black Indicate Founder or intermediate parents with no DNA information nor phenotypic data Direct parents of the mapping populations with DNA information Mapping families used for map construction and QTL discovery
8 LG1 comparison for J14-3 x LC, J14-3 x VS, OB x RF and ICD (consensus map).
9 A HIGH-DENSITY SNP-BASED CONSENSUS MAP FOR DIPLOID ROSES Statistical Summary of Linkage Group Data Marker Density along the 7 Rose LGs Linkage groups Population Map LG1 LG2 LG3 LG4 LG5 LG6 LG7 Overall J14-3 x LC J14-3 x VS OB x RF ICD Marker number Map length (cm) Marker number Map length (cm) Marker number Map length (cm) Marker number Map length (cm)
10 INSIGHTS INTO THE HIGH SYNTENY BETWEEN FRAGARIA VESCA AND ROSA Diploid Rosa Fragaria vesca LGs Populations J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD J14-3xLC J14-3xVS OBxRF ICD
11 INSIGHTS INTO THE HIGH SYNTENY BETWEEN FRAGARIA VESCA AND ROSA a. b. Yan et al. (2018) Horticulture Research. DOI /s
12 Addition of Two Maps to Improve the ICD for FlexQTL J4-6 x RF (62 progeny) LG Length (cm) No. of markers No. of distorted markers (P<0.05) No. of bin markers Biggest gap Overall OB x J3-6 (93 progeny)
13 BLACK SPOT QTL DISCOVERY IN FIFTEEN RELATED DIPLOID ROSE POPULATIONS chr7_ chr7_ chr7_ chr4_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr5_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr5_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr7_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr1_ chr6_ chr6_ chr6_ chr6_ chr6_ chr1_ chr1_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr3_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr6_ chr4_ chr6_ chr4_ chr1_ chr1_ chr3_ chr3_ chr4_ chr4_ chr4_ chr1_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr1_ chr1_ chr1_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr3_ chr4_ chr3_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr4_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr4_ chr2_ chr3_ chr6_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr2_ chr2_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr5_ chr3_ chr3_ chr3_ chr3_ chr5_ chr5_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr1_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr5_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr3_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr5_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr3_ chr3_ chr3_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr2_ chr3_ chr2_ chr2_ chr2_ chr2_ chr2_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr1_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_40345 chr5_ chr5_98049 chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_98223 chr5_ chr5_ chr5_ chr5_ chr5_40337 chr5_ chr3_ chr5_ chr5_ chr1_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr5_ chr2_ chr5_ chr5_ chr5_ chr1_ chr1_ chr6_ chr6_ chr5_ chr5_ chr5_ chr5_ LG Length SNP no Max gap Total Updated consensus map utilizing 5 populations. Map length, SNP number and maximum gaps between SNPs for each LG from the final consensus map for FlexQTL analysis.
14 BLACK SPOT QTL DISCOVERY IN FIFTEEN RELATED DIPLOID ROSE POPULATIONS
15 BLACK SPOT QTL DISCOVERY IN FIFTEEN RELATED DIPLOID ROSE POPULATIONS QTL position Genotype probabilities (positive evidence) LG3 QTL is segregating in parents VS, J4-6 and J14-3 with positive support (76% probability). Genotype probabilities (strong evidence) LG3 QTL is segregating in parents J4-6 and J14-3 with strong support (95% probability).
16 BLACK SPOT QTL DISCOVERY IN FIFTEEN RELATED DIPLOID ROSE POPULATIONS Eleven haplotypes (H1-7 parental, 8-11 recombinant progeny) identified among individuals composed of seven SNPs on LG3 in QTL region cm covering the QTL peak at 41 cm. Comparison between two haplotypes in J14-3 and J4-6 within resulting families J14-3xRF and J4-6xRF on black spot overall rating in 2016 in the QTL region. Comparisons of means were conducted by student s t- test at α = Dots represent each individual s phenotype.1 H3 and H1 are the resistant haplotypes from J14-3 and J4-6, respectively. The resistant H3 haplotype from J14-3 decreased the overall disease rating by 0.9, while the resistant H1 haplotype from J4-6 decreased disease rating by 1.1. z Levels not connected by the same letter are significantly different (α=0.05) y QTL genotype predicated at LG3 41cM x Number of progeny in each QTL genotype class
17 BLACK SPOT QTL DISCOVERY USING PEDIGREE BASED ANALYSIS IN FIFTEEN RELATED DIPLOID ROSE POPULATIONS Documented pedigree of nine directed parents of mapping populations generated by Pedimap 1.2. Traced 7 SNP haplotypes across the LG 3 QTL through the pedigrees to identify inheritance patterns. No definitive conclusion on the origin of the two resistance haplotypes yet. Can conclude the H3 resistant haplotype in J14-3 does not come from DD but from an unknown paternal pollen source (PP-J14-3) and the H1 resistant haplotype might have come from either OB or Rosa wichurana Basye s Thornless (R.wichTless).
18 Next Steps Genome sequence of Old Blush doubled haploid was sequenced at INRA Reanalyzed GBS data from the 15 inter-related diploid rose populations using the rose genome sequence Will allow for marker development for mapped traits which can be used in the breeding program and will aid in the confirmation of the origin of disease resistance Have completed GBS on several of the progenitors of these populations Will improve tracing the origin of the two black spot resistance haplotypes GBS analysis on 435 progeny from 8 additional diploid rose populations for map construction and FlexQTL analysis GBS analysis on 112 rose cultivars and species for GWAS Incorporated the KGD method to estimate relatedness of the progeny from each population based on the SNPs and read depths Tetraploid populations will be genotyped using the Axiom 68k SNP array, followed by map construction and FlexQTL analysis
19 Acknowledgments David Byrne Robert E. Basye Endowment in Rose Genetics Mandy Yan Ellen Young Jeekin Lau Stella Kang Natalie Patterson Natalie Anderson Jizhou Yang Qianni Dong This work was partially funded by the USDA s National Institute of Food and Agriculture (NIFA) Specialty Crop Research Initiative project, Combating Rose Rosette Disease: Short Term and Long Term Approaches ( /SCRI) and RosBREEDII: Combining disease resistance with horticultural quality in new rosaceous cultivars
UNIT 8 BIOLOGY: Meiosis and Heredity Page 148
UNIT 8 BIOLOGY: Meiosis and Heredity Page 148 CP: CHAPTER 6, Sections 1-6; CHAPTER 7, Sections 1-4; HN: CHAPTER 11, Section 1-5 Standard B-4: The student will demonstrate an understanding of the molecular
BS 50 Genetics and Genomics Week of Oct 3 Additional Practice Problems for Section. A/a ; B/B ; d/d X A/a ; b/b ; D/d
BS 50 Genetics and Genomics Week of Oct 3 Additional Practice Problems for Section 1. In the following cross, all genes are on separate chromosomes. A is dominant to a, B is dominant to b and D is dominant
Report of the Research Coordination Meeting Genetics of Root-Knot Nematode Resistance in Cotton Dallas, Texas, October 24, 2007
Report of the Research Coordination Meeting Genetics of Root-Knot Nematode Resistance in Cotton Dallas, Texas, October 24, 2007 Participants: Frank Callahan, Peng Chee, Richard Davis, Mamadou Diop, Osman
Introduc)on to Gene)cs How to Analyze Your Own Genome Fall 2013
Introduc)on to Gene)cs 02-223 How to Analyze Your Own Genome Fall 2013 Overview Primer on gene
Calculation of IBD probabilities
Calculation of IBD probabilities David Evans University of Bristol This Session Identity by Descent (IBD) vs Identity by state (IBS) Why is IBD important? Calculating IBD probabilities Lander-Green Algorithm
Introduction to Genetics
Introduction to Genetics The Work of Gregor Mendel B.1.21, B.1.22, B.1.29 Genetic Inheritance Heredity: the transmission of characteristics from parent to offspring The study of heredity in biology is
SUPPLEMENTARY INFORMATION
Figure S1. Haploid plant produced by centromere-mediated genome elimination Chromosomes containing altered CENH3 in their centromeres (green dots) are eliminated after fertilization in a cross to wild
2013 Breeding Progress for Rust Resistance in Confection Sunflower
2013 Breeding Progress for Rust Resistance in Confection Sunflower Guojia Ma 1,2, Yunming Long 1,3, Sam Markell 2, Tom Gulya 1 and Lili Qi 1 1 USDA, ARS, NCSL, Fargo, ND 2 NDSU Plant Pathology, Fargo,
KEY: Chapter 9 Genetics of Animal Breeding.
KEY: Chapter 9 Genetics of Animal Breeding. Answer each question using the reading assigned to you. You can access this information by clicking on the following URL: https://drive.google.com/a/meeker.k12.co.us/file/d/0b1yf08xgyhnad08xugxsnfvba28/edit?usp=sh
Name Class Date. KEY CONCEPT Gametes have half the number of chromosomes that body cells have.
Section 1: Chromosomes and Meiosis KEY CONCEPT Gametes have half the number of chromosomes that body cells have. VOCABULARY somatic cell autosome fertilization gamete sex chromosome diploid homologous
Linkage analysis and QTL mapping in autotetraploid species. Christine Hackett Biomathematics and Statistics Scotland Dundee DD2 5DA
Linkage analysis and QTL mapping in autotetraploid species Christine Hackett Biomathematics and Statistics Scotland Dundee DD2 5DA Collaborators John Bradshaw Zewei Luo Iain Milne Jim McNicol Data and
The phenotype of this worm is wild type. When both genes are mutant: The phenotype of this worm is double mutant Dpy and Unc phenotype.
Series 1: Cross Diagrams There are two alleles for each trait in a diploid organism In C. elegans gene symbols are ALWAYS italicized. To represent two different genes on the same chromosome: When both
Essential Questions. Meiosis. Copyright McGraw-Hill Education
Essential Questions How does the reduction in chromosome number occur during meiosis? What are the stages of meiosis? What is the importance of meiosis in providing genetic variation? Meiosis Vocabulary
Calculation of IBD probabilities
Calculation of IBD probabilities David Evans and Stacey Cherny University of Oxford Wellcome Trust Centre for Human Genetics This Session IBD vs IBS Why is IBD important? Calculating IBD probabilities
Section 11 1 The Work of Gregor Mendel
Chapter 11 Introduction to Genetics Section 11 1 The Work of Gregor Mendel (pages 263 266) What is the principle of dominance? What happens during segregation? Gregor Mendel s Peas (pages 263 264) 1. The
How to connect to CGIAR wheat (CIMMYT and ICARDA) CRP??- Public wheat breeding for developing world
Wheat breeding only exploits 10% of the diversity available The public sector can t breed elite varieties-how to connect to private sector breeders?? How to connect to CGIAR wheat (CIMMYT and ICARDA) CRP??-
Mendelian Genetics. Introduction to the principles of Mendelian Genetics
+ Mendelian Genetics Introduction to the principles of Mendelian Genetics + What is Genetics? n It is the study of patterns of inheritance and variations in organisms. n Genes control each trait of a living
Chapter 11 INTRODUCTION TO GENETICS
Chapter 11 INTRODUCTION TO GENETICS 11-1 The Work of Gregor Mendel I. Gregor Mendel A. Studied pea plants 1. Reproduce sexually (have two sex cells = gametes) 2. Uniting of male and female gametes = Fertilization
PRINCIPLES OF MENDELIAN GENETICS APPLICABLE IN FORESTRY. by Erich Steiner 1/
PRINCIPLES OF MENDELIAN GENETICS APPLICABLE IN FORESTRY by Erich Steiner 1/ It is well known that the variation exhibited by living things has two components, one hereditary, the other environmental. One
BENCHMARK 1 STUDY GUIDE SPRING 2017
BENCHMARK 1 STUDY GUIDE SPRING 2017 Name: There will be semester one content on this benchmark as well. Study your final exam review guide from last semester. New Semester Material: (Chapter 10 Cell Growth
Introduction to Genetics
Chapter 11 Introduction to Genetics Section 11 1 The Work of Gregor Mendel (pages 263 266) This section describes how Gregor Mendel studied the inheritance of traits in garden peas and what his conclusions
Chapter Eleven: Heredity
Genetics Chapter Eleven: Heredity 11.1 Traits 11.2 Predicting Heredity 11.3 Other Patterns of Inheritance Investigation 11A Observing Human Traits How much do traits vary in your classroom? 11.1 Traits
Variance Component Models for Quantitative Traits. Biostatistics 666
Variance Component Models for Quantitative Traits Biostatistics 666 Today Analysis of quantitative traits Modeling covariance for pairs of individuals estimating heritability Extending the model beyond
Principles of QTL Mapping. M.Imtiaz
Principles of QTL Mapping M.Imtiaz Introduction Definitions of terminology Reasons for QTL mapping Principles of QTL mapping Requirements For QTL Mapping Demonstration with experimental data Merit of QTL
Chapter 5. Heredity. Table of Contents. Section 1 Mendel and His Peas. Section 2 Traits and Inheritance. Section 3 Meiosis
Heredity Table of Contents Section 1 Mendel and His Peas Section 2 Traits and Inheritance Section 3 Meiosis Section 1 Mendel and His Peas Objectives Explain the relationship between traits and heredity.
Lecture WS Evolutionary Genetics Part I 1
Quantitative genetics Quantitative genetics is the study of the inheritance of quantitative/continuous phenotypic traits, like human height and body size, grain colour in winter wheat or beak depth in
Comparative Genomics of Fagaceae
Fagaceae Images.google.com Linkage Map www.quia.com TM www.clipartlord.com Selection of mapping parents SM2 SM1 Predominant pollinator? Progeny Exclusion for Full Sib Linkage Mapping Year Acorns genotyped
THE WORK OF GREGOR MENDEL
GENETICS NOTES THE WORK OF GREGOR MENDEL Genetics-. - Austrian monk- the father of genetics- carried out his work on. Pea flowers are naturally, which means that sperm cells fertilize the egg cells in
Reinforcement Unit 3 Resource Book. Meiosis and Mendel KEY CONCEPT Gametes have half the number of chromosomes that body cells have.
6.1 CHROMOSOMES AND MEIOSIS KEY CONCEPT Gametes have half the number of chromosomes that body cells have. Your body is made of two basic cell types. One basic type are somatic cells, also called body cells,
Biol. 303 EXAM I 9/22/08 Name
Biol. 303 EXAM I 9/22/08 Name -------------------------------------------------------------------------------------------------------------- This exam consists of 40 multiple choice questions worth 2.5
Objectives. Announcements. Comparison of mitosis and meiosis
Announcements Colloquium sessions for which you can get credit posted on web site: Feb 20, 27 Mar 6, 13, 20 Apr 17, 24 May 15. Review study CD that came with text for lab this week (especially mitosis
Name Class Date. Pearson Education, Inc., publishing as Pearson Prentice Hall. 33
Chapter 11 Introduction to Genetics Chapter Vocabulary Review Matching On the lines provided, write the letter of the definition of each term. 1. genetics a. likelihood that something will happen 2. trait
Unit 6 Reading Guide: PART I Biology Part I Due: Monday/Tuesday, February 5 th /6 th
Name: Date: Block: Chapter 6 Meiosis and Mendel Section 6.1 Chromosomes and Meiosis 1. How do gametes differ from somatic cells? Unit 6 Reading Guide: PART I Biology Part I Due: Monday/Tuesday, February
Ch 11.Introduction to Genetics.Biology.Landis
Nom Section 11 1 The Work of Gregor Mendel (pages 263 266) This section describes how Gregor Mendel studied the inheritance of traits in garden peas and what his conclusions were. Introduction (page 263)
Ch 11.4, 11.5, and 14.1 Review. Game
Ch 11.4, 11.5, and 14.1 Review Game What happens to the chromosome number during meiosis? A It doubles B It stays the same C It halves D It becomes diploid Ans: C Gametes are A Sex cells B Sperm and eggs
Mendel and the Gene Idea. Biology Exploring Life Section Modern Biology Section 9-1
Mendel and the Gene Idea Biology Exploring Life Section 10.0-10.2 Modern Biology Section 9-1 Objectives Summarize the Blending Hypothesis and the problems associated with it. Describe the methods used
When one gene is wild type and the other mutant:
Series 2: Cross Diagrams Linkage Analysis There are two alleles for each trait in a diploid organism In C. elegans gene symbols are ALWAYS italicized. To represent two different genes on the same chromosome:
Chapter 10 Sexual Reproduction and Genetics
Sexual Reproduction and Genetics Section 1: Meiosis Section 2: Mendelian Genetics Section 3: Gene Linkage and Polyploidy Click on a lesson name to select. Chromosomes and Chromosome Number! Human body
The phenotype of this worm is wild type. When both genes are mutant: The phenotype of this worm is double mutant Dpy and Unc phenotype.
Series 2: Cross Diagrams - Complementation There are two alleles for each trait in a diploid organism In C. elegans gene symbols are ALWAYS italicized. To represent two different genes on the same chromosome:
Eiji Yamamoto 1,2, Hiroyoshi Iwata 3, Takanari Tanabata 4, Ritsuko Mizobuchi 1, Jun-ichi Yonemaru 1,ToshioYamamoto 1* and Masahiro Yano 5,6
Yamamoto et al. BMC Genetics 2014, 15:50 METHODOLOGY ARTICLE Open Access Effect of advanced intercrossing on genome structure and on the power to detect linked quantitative trait loci in a multi-parent
Linkage and Linkage Disequilibrium
Linkage and Linkage Disequilibrium Summer Institute in Statistical Genetics 2014 Module 10 Topic 3 Linkage in a simple genetic cross Linkage In the early 1900 s Bateson and Punnet conducted genetic studies
Pitahayas: introduction, agrotechniques and breeding
Pitahayas: introduction, agrotechniques and breeding The French Associates Institute for Agriculture and Biotechnology of Drylands May 8 Noemi Tel-Zur The J. Blaustein Institutes for Desert Research Ben-Gurion
-Genetics- Guided Notes
-Genetics- Guided Notes Chromosome Number The Chromosomal Theory of Inheritance genes are located in specific on chromosomes. Homologous Chromosomes chromosomes come in, one from the male parent and one
Detection of triploids in the INRA collection
Wild cherry triploids: a chance for forest breeders? L Serres-Giardi, J Dufour, F Santi VALBRO Growing Valuable Broadleaved Tree species 2008, October 6-8 Freiburg - Germany A L I M E N T A T I O N A G
Supplementary Figure 1. Phenotype of the HI strain.
Supplementary Figure 1. Phenotype of the HI strain. (A) Phenotype of the HI and wild type plant after flowering (~1month). Wild type plant is tall with well elongated inflorescence. All four HI plants
Quiz Section 4 Molecular analysis of inheritance: An amphibian puzzle
Genome 371, Autumn 2018 Quiz Section 4 Molecular analysis of inheritance: An amphibian puzzle Goals: To illustrate how molecular tools can be used to track inheritance. In this particular example, we will
Managing segregating populations
Managing segregating populations Aim of the module At the end of the module, we should be able to: Apply the general principles of managing segregating populations generated from parental crossing; Describe
genome a specific characteristic that varies from one individual to another gene the passing of traits from one generation to the next
genetics the study of heredity heredity sequence of DNA that codes for a protein and thus determines a trait genome a specific characteristic that varies from one individual to another gene trait the passing
Genetic diversity and population structure in rice. S. Kresovich 1,2 and T. Tai 3,5. Plant Breeding Dept, Cornell University, Ithaca, NY
Genetic diversity and population structure in rice S. McCouch 1, A. Garris 1,2, J. Edwards 1, H. Lu 1,3 M Redus 4, J. Coburn 1, N. Rutger 4, S. Kresovich 1,2 and T. Tai 3,5 1 Plant Breeding Dept, Cornell
BIOLOGY LTF DIAGNOSTIC TEST MEIOSIS & MENDELIAN GENETICS
016064 BIOLOGY LTF DIAGNOSTIC TEST MEIOSIS & MENDELIAN GENETICS TEST CODE: 016064 Directions: Each of the questions or incomplete statements below is followed by five suggested answers or completions.
Tutorial Session 2. MCMC for the analysis of genetic data on pedigrees:
MCMC for the analysis of genetic data on pedigrees: Tutorial Session 2 Elizabeth Thompson University of Washington Genetic mapping and linkage lod scores Monte Carlo likelihood and likelihood ratio estimation
Introduction to Genetics
Introduction to Genetics We ve all heard of it, but What is genetics? Genetics: the study of gene structure and action and the patterns of inheritance of traits from parent to offspring. Ancient ideas
is the scientific study of. Gregor Mendel was an Austrian monk. He is considered the of genetics. Mendel carried out his work with ordinary garden.
11-1 The 11-1 Work of Gregor Mendel The Work of Gregor Mendel is the scientific study of. Gregor Mendel was an Austrian monk. He is considered the of genetics. Mendel carried out his work with ordinary
Exam 1 PBG430/
1 Exam 1 PBG430/530 2014 1. You read that the genome size of maize is 2,300 Mb and that in this species 2n = 20. This means that there are 2,300 Mb of DNA in a cell that is a. n (e.g. gamete) b. 2n (e.g.
HEREDITY: Objective: I can describe what heredity is because I can identify traits and characteristics
Mendel and Heredity HEREDITY: SC.7.L.16.1 Understand and explain that every organism requires a set of instructions that specifies its traits, that this hereditary information. Objective: I can describe
AP Biology Unit 6 Practice Test 1. A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8
AP Biology Unit 6 Practice Test Name: 1. A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. How many picograms
Genotype Imputation. Biostatistics 666
Genotype Imputation Biostatistics 666 Previously Hidden Markov Models for Relative Pairs Linkage analysis using affected sibling pairs Estimation of pairwise relationships Identity-by-Descent Relatives
F1 Parent Cell R R. Name Period. Concept 15.1 Mendelian inheritance has its physical basis in the behavior of chromosomes
Name Period Concept 15.1 Mendelian inheritance has its physical basis in the behavior of chromosomes 1. What is the chromosome theory of inheritance? 2. Explain the law of segregation. Use two different
Accounting for read depth in the analysis of genotyping-by-sequencing data
Accounting for read depth in the analysis of genotyping-by-sequencing data Ken Dodds, John McEwan, Timothy Bilton, Rudi Brauning, Rayna Anderson, Tracey Van Stijn, Theodor Kristjánsson, Shannon Clarke
Unit 8 Meiosis and Mendel. Genetics and Inheritance Quiz Date: Jan 14 Test Date: Jan. 22/23
Unit 8 Meiosis and Mendel Genetics and Inheritance Quiz Date: Jan 14 Test Date: Jan. 22/23 UNIT 8 - INTRODUCTION TO GENETICS Although the resemblance between generations of organisms had been noted for
Family resemblance can be striking!
Family resemblance can be striking! 1 Chapter 14. Mendel & Genetics 2 Gregor Mendel! Modern genetics began in mid-1800s in an abbey garden, where a monk named Gregor Mendel documented inheritance in peas
Title. Authors. Characterization of a major QTL for manganese accumulation in rice grain
Title Characterization of a major QTL for manganese accumulation in rice grain Authors Chaolei Liu, Guang Chen, Yuanyuan Li, Youlin Peng, Anpeng Zhang, Kai Hong, Hongzhen Jiang, Banpu Ruan, Bin Zhang,
RFLP facilitated analysis of tiller and leaf angles in rice (Oryza sativa L.)
Euphytica 109: 79 84, 1999. 1999 Kluwer Academic Publishers. Printed in the Netherlands. 79 RFLP facilitated analysis of tiller and leaf angles in rice (Oryza sativa L.) Zhikang Li 1,2,3, Andrew H. Paterson
7.014 Problem Set 6 Solutions
7.014 Problem Set 6 Solutions Question 1 a) Define the following terms: Dominant In genetics, the ability of one allelic form of a gene to determine the phenotype of a heterozygous individual, in which
2. Map genetic distance between markers
Chapter 5. Linkage Analysis Linkage is an important tool for the mapping of genetic loci and a method for mapping disease loci. With the availability of numerous DNA markers throughout the human genome,
Ch. 10 Sexual Reproduction and Genetics. p
Ch. 10 Sexual Reproduction and Genetics p. 270 - 10.1 Meiosis p. 270-276 Essential Question Main Idea! Meiosis produces haploid gametes Where are the instructions for each trait located in a cell?! On
Fei Lu. Post doctoral Associate Cornell University
Fei Lu Post doctoral Associate Cornell University http://www.maizegenetics.net Genotyping by sequencing (GBS) is simple and cost effective 1. Digest DNA 2. Ligate adapters with barcodes 3. Pool DNAs 4.
The Work of Gregor Mendel
11-1 The 11-1 Work of Gregor Mendel The Work of Gregor Mendel Who was Gregor Mendel? Define genetics. Define heredity. In Mendel s time there were primarily two hypotheses concerning the mechanism of heredity.
Supporting Online Material for
www.sciencemag.org/cgi/content/full/331/6019/876/dc1 Supporting Online Material for Synthetic Clonal Reproduction Through Seeds Mohan P. A. Marimuthu, Sylvie Jolivet, Maruthachalam Ravi, Lucie Pereira,
Introduction to Genetics
Introduction to Genetics We ve all heard of it, but What is genetics? Genetics: the study of gene structure and action and the patterns of inheritance of traits from parent to offspring. Ancient ideas
Assessment of Genetic Diversity of Pawpaw Cultivars with Inter-Simple Sequence Repeat Markers
Assessment of Genetic Diversity of Pawpaw Cultivars with Inter-Simple Sequence Repeat Markers Kirk W. Pomper*, Sheri B. Crabtree, and Snake C. Jones Kentucky State University What is Pawpaw? Asimina triloba
Genetics test HL - model answers
Genetics test HL - model answers Multiple choice questions 1. In Guinea pigs the allele for tufts of fur called rosette, (R) is dominant to the smooth fur allele (r). In a different gene the allele for
Solutions to Problem Set 4
Question 1 Solutions to 7.014 Problem Set 4 Because you have not read much scientific literature, you decide to study the genetics of garden peas. You have two pure breeding pea strains. One that is tall
Legend: S spotted Genotypes: P1 SS & ss F1 Ss ss plain F2 (with ratio) 1SS :2 WSs: 1ss. Legend W white White bull 1 Ww red cows ww ww red
On my honor, this is my work GENETICS 310 EXAM 1 June 8, 2018 I. Following are 3 sets of data collected from crosses: 1. Spotted by Plain gave all spotted in the F1 and 9 spotted and 3 plain in the F2.
Unit 5: Chapter 11 Test Review
Name: Date: Period: Unit 5: Chapter 11 Test Review 1. Vocabulary you should know. Recommendation (optional): make flashcards, or write the definition down. Make sure you understand the meanings of all
Meiosis and Mendel. Chapter 6
Meiosis and Mendel Chapter 6 6.1 CHROMOSOMES AND MEIOSIS Key Concept Gametes have half the number of chromosomes that body cells have. Body Cells vs. Gametes You have body cells and gametes body cells
Molecular characterisation of a population derived from microspores of Brassica napus B. carinata hybrids
Molecular characterisation of a population derived from microspores of Brassica napus B. carinata hybrids Annaliese Mason 1, Matthew Nelson 1,2, Guijun Yan 1 and Wallace Cowling 1,2 1 School of Plant Biology,
Sexual Reproduction and Genetics
Chapter Test A CHAPTER 10 Sexual Reproduction and Genetics Part A: Multiple Choice In the space at the left, write the letter of the term, number, or phrase that best answers each question. 1. How many
Lecture 7 (FW) February 11, 2009 Phenotype and Genotype Reading: pp
Lecture 7 (FW) February 11, 2009 Phenotype and Genotype Reading: pp. 51-62 Annoucement: A review session for the first mid term will be held on Tuesday, 2/24, from 5-6:30 PM in 159 Mulford Hall. The mid
BREEDING, GENETICS, AND PHYSIOLOGY. Phenotypic Analysis of the 2006 MY2 Mapping Population in Arkansas
BREEDING, GENETICS, AND PHYSIOLOGY Phenotypic Analysis of the 2006 MY2 Mapping Population in Arkansas E.J. Boza, K.A.K. Moldenhauer, R.D. Cartwright, S. Linscombe, J.H. Oard, and M.M. Blocker ABSTRACT
Problem Set 3 10:35 AM January 27, 2011
BIO322: Genetics Douglas J. Burks Department of Biology Wilmington College of Ohio Problem Set 3 Due @ 10:35 AM January 27, 2011 Chapter 4: Problems 3, 5, 12, 23, 25, 31, 37, and 41. Chapter 5: Problems
Interest Grabber. Analyzing Inheritance
Interest Grabber Section 11-1 Analyzing Inheritance Offspring resemble their parents. Offspring inherit genes for characteristics from their parents. To learn about inheritance, scientists have experimented
Advance Organizer. Topic: Mendelian Genetics and Meiosis
Name: Row Unit 8 - Chapter 11 - Mendelian Genetics and Meiosis Advance Organizer Topic: Mendelian Genetics and Meiosis 1. Objectives (What should I be able to do?) a. Summarize the outcomes of Gregor Mendel's
Meiosis -> Inheritance. How do the events of Meiosis predict patterns of heritable variation?
Meiosis -> Inheritance How do the events of Meiosis predict patterns of heritable variation? Mendel s peas 1. Genes determine appearance (phenotype) 2. Genes vary and they are inherited 3. Their behavior
A mixed model based QTL / AM analysis of interactions (G by G, G by E, G by treatment) for plant breeding
Professur Pflanzenzüchtung Professur Pflanzenzüchtung A mixed model based QTL / AM analysis of interactions (G by G, G by E, G by treatment) for plant breeding Jens Léon 4. November 2014, Oulu Workshop
Lesson 4: Understanding Genetics
Lesson 4: Understanding Genetics 1 Terms Alleles Chromosome Co dominance Crossover Deoxyribonucleic acid DNA Dominant Genetic code Genome Genotype Heredity Heritability Heritability estimate Heterozygous
Name Period. 3. How many rounds of DNA replication and cell division occur during meiosis?
Name Period GENERAL BIOLOGY Second Semester Study Guide Chapters 3, 4, 5, 6, 11, 14, 16, 17, 18 and 19. SEXUAL REPRODUCTION AND MEIOSIS 1. What is the purpose of meiosis? 2. Distinguish between diploid
Unit 7 Genetics. Meiosis
NAME: 1 Unit 7 Genetics 1. Gregor Mendel- was responsible for our 2. What organism did Mendel study? 3. Mendel stated that physical traits were inherited as 4. Today we know that particles are actually
Name: Period: EOC Review Part F Outline
Name: Period: EOC Review Part F Outline Mitosis and Meiosis SC.912.L.16.17 Compare and contrast mitosis and meiosis and relate to the processes of sexual and asexual reproduction and their consequences
Part 2- Biology Paper 2 Inheritance and Variation Knowledge Questions
Part 2- Biology Paper 2 Inheritance and Variation Knowledge Questions AQA TRILOGY Biology (8464) from 2016 Topic T4.6 Inheritance, variation and evolution Topic Student Checklist R A G Describe features
Chapter 2: Extensions to Mendel: Complexities in Relating Genotype to Phenotype.
Chapter 2: Extensions to Mendel: Complexities in Relating Genotype to Phenotype. please read pages 38-47; 49-55;57-63. Slide 1 of Chapter 2 1 Extension sot Mendelian Behavior of Genes Single gene inheritance
Lesson Overview Meiosis
11.4 As geneticists in the early 1900s applied Mendel s laws, they wondered where genes might be located. They expected genes to be carried on structures inside the cell, but which structures? What cellular
1 Springer. Nan M. Laird Christoph Lange. The Fundamentals of Modern Statistical Genetics
1 Springer Nan M. Laird Christoph Lange The Fundamentals of Modern Statistical Genetics 1 Introduction to Statistical Genetics and Background in Molecular Genetics 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Segregation distortion in F 2 and doubled haploid populations of temperate japonica rice
c Indian Academy of Sciences RESEARCH NOTE Segregation distortion in F 2 and doubled haploid populations of temperate japonica rice MASUMI YAMAGISHI 1,2,6, YOSHINOBU TAKEUCHI 3,7, ISAO TANAKA 4, IZUMI
Unit 2 Lesson 4 - Heredity. 7 th Grade Cells and Heredity (Mod A) Unit 2 Lesson 4 - Heredity
Unit 2 Lesson 4 - Heredity 7 th Grade Cells and Heredity (Mod A) Unit 2 Lesson 4 - Heredity Give Peas a Chance What is heredity? Traits, such as hair color, result from the information stored in genetic
THINK ABOUT IT. Lesson Overview. Meiosis. As geneticists in the early 1900s applied Mendel s laws, they wondered where genes might be located.
Notes THINK ABOUT IT As geneticists in the early 1900s applied Mendel s laws, they wondered where genes might be located. They expected genes to be carried on structures inside the cell, but which structures?
Labs 7 and 8: Mitosis, Meiosis, Gametes and Genetics
Biology 107 General Biology Labs 7 and 8: Mitosis, Meiosis, Gametes and Genetics In Biology 107, our discussion of the cell has focused on the structure and function of subcellular organelles. The next
7.014 Problem Set 6. Question 1. MIT Department of Biology Introductory Biology, Spring 2004
MIT Department of Biology 7.014 Introductory Biology, Spring 2004 Name: 7.014 Problem Set 6 Please print out this problem set and record your answers on the printed copy. Problem sets will not be accepted
The history of Life on Earth reflects an unbroken chain of genetic continuity and transmission of genetic information:
9/26/05 Biology 321 Answers to optional challenge probability questions posed in 9/23/05lecture notes are included at the end of these lecture notes The history of Life on Earth reflects an unbroken chain
Chromosome duplication and distribution during cell division
CELL DIVISION AND HEREDITY Student Packet SUMMARY IN EUKARYOTES, HERITABLE INFORMATION IS PASSED TO THE NEXT GENERATION VIA PROCESSES THAT INCLUDE THE CELL CYCLE, MITOSIS /MEIOSIS AND FERTILIZATION Mitosis