Advanced Experimental Design

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Advanced Experimental Design Topic 8 Chapter : Repeated Measures Analysis of Variance Overview Basic idea, different forms of repeated measures Partialling out between subjects effects Simple repeated measures ANOVA structural model New assumptions Sphericity & equality of covariance matrices Mixed model (adding a between subjects factor) SPSS example(s) Repeated measures ANOVA Similar to switch from independent samples t to paired samples t-test Basic design consists of the same subject being measured on all levels of DV different conditions measures taken over time Advantage: reduces the overall variability within subjects; allows removal of subject differences from the error term

Different forms of repeated measures Time same measurement at multiple points in time Different conditions Different versions of the same measuring device Matched triads or larger groups Potential biases Practice effects Fatigue Confounding effects Partitioning Variability - Oneway In oneway ANOVA, between groups and within groups Total SS Between Groups SS Within Groups SS 5 Partitioning Variability Repeated Measures In Repeated Measures ANOVA Between subjects SS Within subjects variability between treatments variance error variance - individual variability in impact of treatment Repeated measure over more than two levels Hypothesis test focuses on change over time (or across treatments) 6

Partitioning Variability Repeated Measures SS divided into between subjects and within subjects, which is then divided further Total SS (kn-) Between subjects (n-) Within subjects (n(k-)) Between treatments (k-) Error ((n-)(k-)) 7 Partialling out subject effects each subjects contribution to the overall variability is placed on a common footing Howell Table., Pg. Each subject s scores expressed as deviations from their overall mean score 8 Partialling out subject effects Treatment Subject 0 0 9 7 0 Mean..67 7.00.67 Sub -. -.67-5.00 -.67-0. 0..00-0.67.67..00. M Mean 6 9 8.67 M -.67 0.. Original...0 Deviations.59.9 0.7 9

Structural model for repeated measures ANOVA Represents each individual score for each treatment in terms of the model parameters Used to derive expected mean squares for the different portions of the total variance F ratios that we will use to evaluate our null hypothesis 0 X Structural model = µ + π + τ + πτ + e ij i j ij ij µ= grand mean π i = a constant associated with the i th person τ j = a constant associated with the j th treatment πτ ij = the subject by treatment interaction e ij = the experimental error for the i th person under the j th treatment Assumptions Compound symmetry of the covariance matrix covariance matrix = unstandardized correlation matrix Variances on the diagonal, off diagonal elements are covariances between variables Σ= population Σ= ˆ estimate

Covariance Crossproducts of deviations from the mean Dividing by product of sd s turns into a correlation coefficient ( X X)( Y Y) COVXY = N ΣXΣY XY or N N COV r = SS x xy y Compound symmetry/sphericity Compound symmetry: variances all about the same; covariances all about the same variances and covariances do not need to be similar Sphericity: less restrictive condition, which can be present in the absence of compound symmetry repeated-measures ANOVA equivalent of the homogeneity of variances assumption SPSS provides Mauchley s test of Sphericity Run example from Table. in text in SPSS Mixed model add a grouping factor a little more complicated partitioning the variance in our DV in both major partitions, the S s within groups term represents the error or residual term 5 5

Partitioning Variability mixed model, between and within Three hypothesis tests group, interval, interval x group Between subjects (ng-) Total SS (ign-) i = intervals g = groups n = sample size Within subjects (tot df df btw) Groups (g-) S s within Groups (n g) Intervals (i -) I x G (i -)(g -) I x S s w/in groups (n-g)(i-) Adapted Adapted from from Howell Howell, (007) Pg. 8 pg 5 6 Another assumption equality of covariance matrices across groups interrelationships among intervals of the DV do not differ across groups SPSS provides us with Box s test of the equality of covariance matrices Mixed model example in SPSS, Table. data from text 7 6