Calculus for the Life Sciences

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Calculus for the Life Sciences Lecture Notes and Functions Joseph M. Mahaffy, jmahaffy@mail.sdsu.edu Department of Mathematics and Statistics Dynamical Systems Group Computational Sciences Research Center San Diego State University San Diego, CA 92182-7720 http://www-rohan.sdsu.edu/ jmahaffy Spring 2017 Lecture Notes and Funct (1/23)

Outline 1 Formic Acid Equilibrium Constant, K a Concentration of Acid 2 3 Vertex Intersection of Line and Parabola 4 Height of Ball Lecture Notes and Funct (2/23)

Formic Acid Equilibrium Constant, K a Concentration of Acid Many of the organic acids found in biological applications are weak acids Weak acid chemistry is important in preparing buffer solutions for laboratory cultures Lecture Notes and Funct (3/23)

Formic Acid Formic Acid Equilibrium Constant, K a Concentration of Acid Ants Formic acid (HCOOH) is a relatively strong weak acid that ants use as a defense The strength of this acid makes the ants very unpalatable to predators Lecture Notes and Funct (4/23)

Acid Chemistry Formic Acid Equilibrium Constant, K a Concentration of Acid The Chemistry of Dissociation for formic acid: HCOOH k 1 H + +HCOO. k 1 Each acid has a distinct equilibrium constant K a that depends on the properties of the acid and the temperature of the solution For formic acid, K a = 1.77 10 4 Let [X] denote the concentration of chemical species X Formic acid is in equilibrium, when: K a = [H+ ][HCOO ] [HCOOH] Lecture Notes and Funct (5/23)

Formic Acid Equilibrium Constant, K a Concentration of Acid Concentration of [H + ] 1 Based on K a and amount of formic acid, we want to find the concentation of [H + ] If formic acid is added to water, then [H + ] = [HCOO ] If x is the normality of the solution, then x = [HCOOH]+[HCOO ] It follows that [HCOOH] = x [H + ] Thus, K a = [H+ ][H + ] x [H + ] Lecture Notes and Funct (6/23)

Formic Acid Equilibrium Constant, K a Concentration of Acid Concentration of [H + ] 2 The previous equation is written [H + ] 2 +K a [H + ] K a x = 0 This is a quadratic equation in [H + ] and is easily solved using the quadratic formula [H + ] = 1 2 ( K a + ) Ka 2 +4K a x Only the positive solution is taken to make physical sense Lecture Notes and Funct (7/23)

Example for [H + ] Formic Acid Equilibrium Constant, K a Concentration of Acid Find the concentration of [H + ] for a 0.1N solution of formic acid Solution: Formic acid has K a = 1.77 10 4, and a 0.1N solution of formic acid gives x = 0.1 The equation above gives [H + ] = 1 2 ( 0.000177 + ) (0.000177) 2 +4(0.000177)(0.1) or [H + ] = 0.00412 Since ph is defined to be log 10 [H + ], this solution has a ph of 2.385 Lecture Notes and Funct (8/23)

Review of Quadratic Equation: The general quadratic equation is ax 2 +bx+c = 0 Three methods for solving quadratics: 1 Factoring the equation 2 The quadratic formula 3 Completing the Square x = b± b 2 4ac 2a Lecture Notes and Funct (9/23)

Example of Factoring a Quadratic Equation Consider the quadratic equation: x 2 +x 6 = 0 Find the values of x that satisfy this equation. Skip Example Solution: This equation is easily factored (x+3)(x 2) = 0 Thus, x = 3 and x = 2 Lecture Notes and Funct (10/23)

Example of the Quadratic Formula Consider the quadratic equation: x 2 +2x 2 = 0 Find the values of x that satisfy this equation. Skip Example Solution: This equation needs the quadratic formula x = 2± 2 2 4(1)( 2) 2(1) = 1± 3 or x = 2.732 and x = 0.732 Lecture Notes and Funct (11/23)

Example with Complex Roots Consider the quadratic equation: x 2 4x+5 = 0 Find the values of x that satisfy this equation. Skip Example Solution: We solve this by completing the square Rewrite the equation x 2 4x+4 = 1 (x 2) 2 = 1 or x 2 = ± 1 = ±i This has no real solution, only the complex solution x = 2±i Lecture Notes and Funct (12/23)

Vertex Intersection of Line and Parabola The general form of the is f(x) = ax 2 +bx+c, where a 0 and b and c are arbitrary. The graph of y = f(x) produces a parabola Lecture Notes and Funct (13/23)

Vertex Vertex Intersection of Line and Parabola Write the quadratic function (recall completing the squares) y = a(x h) 2 +k The Vertex of the Parabola is the point (x v,y v ) = (h,k) The parameter a determines the direction the parabola opens If a > 0, then the parabola opens upward If a < 0, then the parabola opens downward As a increases the parabola narrows Lecture Notes and Funct (14/23)

Finding the Vertex Vertex Intersection of Line and Parabola Given the quadratic function y = ax 2 +bx+c There are three common methods of finding the vertex The x-value is x = b 2a The midpoint between the x-intercepts (if they exist) Completing the square Lecture Notes and Funct (15/23)

Vertex Intersection of Line and Parabola Example of Line and Parabola 1 Consider the functions f 1 (x) = 3 2x and f 2 = x 2 x 9 Skip Example Find the x and y intercepts of both functions Find the slope of the line Find the vertex of the parabola Find the points of intersection Graph the two functions Lecture Notes and Funct (16/23)

Vertex Intersection of Line and Parabola Example of Line and Parabola 2 Solution: The line f 1 (x) = 3 2x Has y-intercept y = 3 Has x-intercept x = 3 2 Has slope m = 2 Lecture Notes and Funct (17/23)

Vertex Intersection of Line and Parabola Example of Line and Parabola 3 Solution (cont): The parabola f 2 = x 2 x 9 Has y-intercept y = 9, since f 2 (0) = 9 By quadratic formula the x-intercepts satisfy x = 1± 37 2 or x 2.541, 3.541 Vertex satisfies x = 1 2 and y = 37 4 Lecture Notes and Funct (18/23)

Vertex Intersection of Line and Parabola Example of Line and Parabola 4 Solution (cont): The points of intersection of f 1 (x) = 3 2x and f 2 = x 2 x 9 Find the points of intersection by setting the equations equal to each other 3 2x = x 2 x 9 or x 2 +x 12 = 0 Factoring (x+4)(x 3) = 0 or x = 4,3 Points of intersection are (x 1,y 1 ) = ( 4,11) or (x 2,y 2 ) = (3, 3) Lecture Notes and Funct (19/23)

Vertex Intersection of Line and Parabola Example of Line and Parabola 5 Solution (cont): Graph of the functions 25 Intersection: Line and Quadratic 20 15 10 y = x 2 x 9 ( 4, 11) y 5 0 5 y = 3 2x (3, 3) 10 6 4 2 0 2 4 6 x Lecture Notes and Funct (20/23)

Height of Ball Height of a Ball 1 A ball is thrown vertically with a velocity of 32 ft/sec from ground level (h = 0). The height of the ball satisfies the equation: h(t) = 32t 16t 2 Skip Example Sketch a graph of h(t) vs. t Find the maximum height of the ball Determine when the ball hits the ground Lecture Notes and Funct (21/23)

Height of Ball Example of Line and Parabola 2 Solution: Factoring h(t) = 32t 16t 2 = 16t(t 2) This gives t-intercepts of t = 0 and 2 The midpoint between the intercepts is t = 1 Thus, the vertex is t v = 1, and h(1) = 16 Lecture Notes and Funct (22/23)

Height of Ball Example of Line and Parabola 3 Solution (cont): The graph is Height of Ball 15 Height (ft) 10 5 h(t) = 32 t 16 t 2 0 0 0.5 1 1.5 2 t (sec) The maximum height of the ball is 16 ft The ball hits the ground at t = 2 sec Lecture Notes and Funct (23/23)