Disposable Caging: Simpler Protocols, Tighter Biosecurity
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1 Disposable Caging: Simpler Protocols, Tighter Biosecurity presented by Jim Fallon, President / COO, Innovive Inc Disposable Caging: Simpler Protocols, Tighter Biosecurity 1
2 Jim Fallon, President & COO Innovive Inc As President and COO of Innovive Inc, Jim Fallon has been involved in the implementation of disposable caging at over 100 facilities worldwide since 2005, including several large newconstruction projects. He has seen first hand the dos and don'ts associated with this technology and been closely tied to the many innovations and best practices that have emerged over the past 6 years. Prior to joining Innovive Jim has 20 years experience implementing new technologies, facilitating process change and helping his customers realize value. He's led companies in the software and telecommunication industries and was a consultant with the Boston Consulting Group. He holds a bachelor of science degree from the University of Wisconsin-Madison and an MBA from the University of Texas at Austin. jfallon@innoviveinc.com Disposable Caging: Simpler Protocols, Tighter Biosecurity 2
3 Overview: I. Comparison of Traditional and Disposable Process Flow II. III. IV. Achieving Improvements in Bio-security Case Studies Q&A Disposable Caging: Simpler Protocols, Tighter Biosecurity 3
4 I. Comparison of Traditional and Disposable Process Flow Disposable Caging: Simpler Protocols, Tighter Biosecurity 4
5 There Are Many Processes in Traditional Vivarium Workflows DIRTY CAGES AND BOTTLES SOILED BEDDING AND WASTE CLEAN CAGES, BOTTLES BEDDING, FEED Disposable Caging: Simpler Protocols, Tighter Biosecurity 5
6 Disposable Caging Simplifies Vivarium Workflows WATER CAGING, FEED CLEAN CAGES USED CAGES+WASTE Disposable Caging: Simpler Protocols, Tighter Biosecurity 6
7 Fewer Process Steps Improves Biosecurity WATER CAGING, FEED CLEAN CAGES USED CAGES+WASTE DISPOSABLE CAGING Material Separation Fewer process steps One way material flow No dirty hallways Simpler protocols DIRTY CAGES AND BOTTLES SOILED BEDDING AND WASTE TRADITIONAL CAGING CLEAN CAGES, BOTTLES BEDDING, FEED Many process steps Greater bio-security risk More training required Circular flow Disposable Caging: Simpler Protocols, Tighter Biosecurity 7
8 II. Achieving Improvements in Bio-Security Disposable Caging: Simpler Protocols, Tighter Biosecurity 8
9 A Clean Bedded Cage Using Traditional Caging Requires Many Process Steps Complexity of maintaining bio-security increases with number of steps Disposable Caging: Simpler Protocols, Tighter Biosecurity 9
10 A Consistent Supply of Clean Water- Disposables Yields a Simpler Process Variability increases with the number of process steps Disposable Caging: Simpler Protocols, Tighter Biosecurity 10
11 Disposable Caging Protocols Enable Improvements in Bio-Security Clean Irradiated, caging components are placed under the hood Cage Change Protocol is Virtually the Same as traditional Caging Bags can be sealed and collected from under the hood Outside of the bag is wiped down for removal from facility Disposable Caging: Simpler Protocols, Tighter Biosecurity 11
12 Case Study 8,000 Cage Mouse Facility CLOSED-LOOP RECYCLING 300 SQ.FT DEDICATED ONE-WAY FLOW NO DIRTY HALLWAY Monthly pick-up Guaranteed recycling of the plastic Guaranteed composting of the bedding RECEIVING AND STORAGE Irradiated caging components Pre-bedded cage bottoms with 1/8 corn cob bedding Pre-filled bottles with acidified ph of Approximately 20 pallets per month CAGE CHANGE PROCESS All changeouts performed under the hood Used cages bagged under the hood Bags are sprayed and wiped for removal from facility Results: Improved bio-security Increased capacity Lower utilities Lower headcount Fewer injury claims Simplified training Disposable Caging: Simpler Protocols, Tighter Biosecurity 12
13 Case Study Bio Security Improvements 8000 cage mouse facility Open to researchers History of MPV Ongoing sentinel program Failing cage wash led to conversion to disposable caging Identical facility next door with same health profile did not convert to disposable caging No other process or equipment changes were implemented 33% incident decrease following implementation Incidences doubled during the same time period at the facility next door Disposable Caging: Simpler Protocols, Tighter Biosecurity 13
14 CONCLUSION THANK YOU The mission is accomplished through the design, development and delivery of an End-To-End Disposable Caging Solution: Research-Ready Disposable Caging simplifies vivarium operations, reduces cage processing steps and increases biosecurity. A consistent supply of research ready, pre-bedded caging and pre-filled water for rats and mice to your facility; Convenient recycling and composting services after use, Extensive logistical support and customer service. Disposable Caging: Simpler Protocols, Tighter Biosecurity 14
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