Journal of Chemical and Pharmaceutical Research, 2013, 5(12): Research Article

Transcription

1 Available online Journal o Chemical and Pharmaceutical Research, 03, 5(): Research Article ISS : CODE(USA) : JCPRC5 Otimization o the middle-die hole chamer o harmaceutical tablet ress Wei HE and Xiong-wei Wang Ocean College o Hebei Agricultural University, Qinhuangdao, Hebei, China Great Wall College, China University o Geosciences, Baoding Hebei, China ABSTRACT To solve the roblems with increasing die wear in the tablet roduction rocess, this research attemts to study the relationshi between mold hole chamer and stress and deormation rom the ring mold hole axial ath, through modeling die bore and inite element static analysis with CATIA V5R6. The conclusion is when middle-die hole chamer is 67.5, die wear gets smaller. Aterwards, the exeriment o granulation ractice shows that the modiied middle-die can remarkablely revent mold bore wear. Key words: mold bore wear, chamer, otimization, CATIAV5 R6 ITRODUCTIO In the roduction o tablets, the die is critical or the quality o the tablets. Ater longtime use o the die, the die aerture wear leads to misalignment o hole unch and die hole, which the moving unch rod riction increases greatly. The roer roduction can not roceed when the riction gets more serious. The cause o the die bore wear is multiaceted, which includes raw materials, rocess and the way it is used or the irst time, etc. seciically, the more the axial load is, the more the loss is to the mold. This article ocuses on the relationshi between manuacturing arameters o cone angle o ring mold material guide hole and the wear rom the die hole. In order to study the relations study the relationshi between mold hole chamer and stress and deormation rom the ring mold hole axial ath, CATIA V5 R6 is utilized to comlete the die hole modeling and inite element static analysis, and ultimately rovides a basis or otimization o the structure o the mold. The roblem o mold bore wear die can be solved rom the ersective o design. EXPERIMETAL SECTIO Establish the structure model o mid-mode The mode structure Exerimental equiment: Hunan Zhongcheng Pharmaceutical Machinery Factory TDP-.5 herbal ills molding machine. Technical Parameters: Maximum tablet ressure5k, Maximum tablet diametermm, Filling deth, Dimensions mm, and Weight mm, Yield 3000 c / h, Power 3700W, Seed400 r / min 95 kg. The structure and arameters o the die hole are shown as Fig.. The main arameters o the die hole: the diameter o the die hole d angleα 60, Die hole chamerθ 60. mm, chamered outer diameter d.mm, mold thickness L mm, eed 043

2 Wei HE and Xiong-wei Wang J. Chem. Pharm. Res., 03, 5(): Fig. the structure o the middle-die The establishment o structure model Geometric modeling (shown as Fig.) is indisensable or inite elements analysis with CATIA V5R6, Because o o hole model is axially symmetric, it is easible to build /4 o the model. Provide resectivelyα 60 45, o arts models are established (shown as Fig.3) [,5], with 60 o. α Fig. structure o the middle-die Hole and orce diagram Fig.3 3D model o the eed angle o

3 Wei HE and Xiong-wei Wang J. Chem. Pharm. Res., 03, 5(): Calculation o inite elements loaded o the die hole [6] First, make calculation o inite elements loaded with die hole as the object; and then analysis o stress: (shown as Fig.3) F 一 axial orce, ---Chamer cone riction, ---Friction rom inner surace o mold hole, ---ositive ressure in the eed hole, --- ositive ressure rom inner surace in die hole. From the analysis above, the shaed material coming rom the die hole satisies the ollowing relationshi: F µ θ θ + µ sin + cos () In order to make inite element analysis, the ollowing assumtions are made: the riction coeicient between chamer cone, the die hole and the material, between the uer and lower unches, according to the related reerences, µ µ 0. ; I the ressures rom conical surace and the ressure rom inner surace in die hole are equal, so A A πh ( d sinθ πdh h ( d sinθdh () In(), A A are chamering cone surace area in the die hole and cylindrical surace area, ormula() led into (), then F µ sinθ + cosθ + µ µ F h ( µ sinθ + cosθ ) h ( tgθ µ + sinθdh + ( µ sinθ + cosθ ) h ( d sinθdh (3) I F is given the maximum value, F 5K. The other arameters are d mm, h mm, h mm. From ormula () and (3), when θ varies, varies. According to ormula()and(3), the values o,,, The inite elements load are added to 3 models, we can see in Tab., varies also. For µ is known, can be obtained when θ varies. Tab. the values o,,, when θ varies. eed cone angle die hole chamer orce bearing o middle-die hole ID α θ 单位 :K When the die hole is loaded using CATIA V5 to make stress analysis, and will it s needed to igure out the ressure and resolution. Take 60 chamer o cone hole or examle, A 7 0 m, A m, the results are shown in Tab.. 045

4 Wei HE and Xiong-wei Wang J. Chem. Pharm. Res., 03, 5(): Tab. ressure and orce resolution o middle-die hole eed cone angle die hole chamer ressure and orce resolution o middle-die hole α θ 0.36K.3 K K 6. K x, y, z x, y, z 0, 0, ,0, a.6 0 a ext, we can make calculations o division o tetrahedral grids[3]. in the latorm o Advanced Meshing Tools, in the dialog box o Tetrahedral Grid Row Dierentiator, the grid size is given 0.5mm, absolute sag value is 0.mm. Ater the entity is hidden, the result can be seen in Fig.4. Fig.4 inite element mesh generation Fig.5 art constrained Fig.6 art loading Analysis o the inite element stress[7,] In the latorm o Generative Structural Analysis, the 3D roerties are attached to the given arts. Set clamed boundary conditions and load arts model, see Fig.5 and 6. aterwards, loads are made in the chamer cone hole and the cylindrical inner surace o the mold hole. Finally, calculations are made, the results are shown in Fig.7. (a)die bore chamer 60 max.70 0 Pa σ (b) die bore chamer 67.5 σ max.6 0 Pa Fig.7 the Von Mises stress distribution o chamer

5 Wei HE and Xiong-wei Wang J. Chem. Pharm. Res., 03, 5(): RESULTS AD DISCUSSIO In Fig., the Von Mises stress distribution o the chamer o die hole shows that the stress on o chamer 67.5 is much less than that o 60,which is widely used in ractice. The greatest stress is exerted on the inner surace in comressed cylindrical hole at chamer o 67.5, and at chamer o 60, it s on cone o eed hole, where eed cone hole tends to be worn. Sometimes, lastic deormation occurs. Another study shows when the seed is ixed, Taer o the die hole has remarkable eect on comressed shaing[9,0]. When taerα increases rom 30 to 45, the biggest comressed density in granulation increases too, with the smaller rate o energy consumtion; while taer α increases rom 45 to 60, the biggest comressed density in granulation decreases with much bigger rate o energy consumtion. When taer α is 30, it is not conducive to comression molding; when α 45 (θ 67.5 ), the comressed density becomes biggest, with the least rate o energy consumtion and the best comression molding eect. COCLUSIO This article takes the die bore wear and some arameters as the research objects, making some imortant ruits: First, the conclusion that the die bore chamer o 67.5 is much better in roduction is derived rom kinds o analysis axial Von Mises stress distribution, combined with the relationshi analysis between rates o comression, energy consumtion, and cone angle o eed hole. Second, all these results are alied into the mold temlate o the herbal ills molding machine TDP-.5, to imrove the arameters o chamering structure. The exeriment indicates that the mid-mold with aerture o mm, die bore chamer 67.5 can manuacture 3000~3500 c / h. Comared to the die bore chamer o 60, it can imrove the roduction, guarantee the quality o tablets, relieve die wear and rolong the lietime o the mold, so the cost can be reduced. Acknowledgements We kindly acknowledge inancial suort by the science and technology research and develoment Program o HeBei rovince (o. 009). the author is also very grateul or the suort rovided by the science and technology research and develoment Program o Qinhuangdao city (o 000A6). It is also imortant to note that these two authors contributed to this aer equally and should be regarded as co-irst authors. REFERECES []Shi hao-yun, Chen lan. Mechanical and Electrical Inormation,009,9,-3. []xiao zhan-ing. Feed World,006,4,34-3. [3]Xie long-han. CATIA V5 Part Design.005,-56. [4]Lingeng LI, Changhui XU, Yunxia Chen, et al. Journal o Chemical and Pharmaceutical Research, 03, 5(9): [5]Dong Kang-xing and Jiang Min-zheng. Journal o Chemical and Pharmaceutical Research, 03, 5(9):-7. [6]Sheng Xuan-yu, Li Ming-zhi. CATIA V5 R7 Finite Element Analysis case tutorials,009,4-4. [7]Jing-u JIA and Wei HE. Journal o Chemical and Pharmaceutical Research, 03, 5(): []Srashti Dwivedi, Priyanka Jain. Journal o Chemical and Pharmaceutical Research, 03, 5(6):-3. [9] SHI Shui-juan, WU Kai, Jiang Ai-jun. Machinery Design&Manuacture,0 (),3-40. [0] Wu Kai, Shi Shuijuan, Peng Binbin, etc. Transactions o the CSAE,00 (6),