BIO-DATA. Educational Qualification : Degree / Year College /University Subjects Diploma

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1 BIO-DATA Name : Dr. H. M. Meshram Designation : Scientist F Address : Organic Division- I Discovery Laboratory Indian Institute of Chemical Technology Hyderabad (A. P), India hmmeshram@yahoo.com Phone No : (off) (Res) Date of Birth : Nationality : Indian Marital Status : Married Educational Qualification : Degree / Year College /University Subjects Diploma B.Sc Dr. Ambedkar College, Chemistry, Botany, Zoology Nagpur M.Sc Vidardha Mahavidhyalaya, Organic Chemistry Amaravati M.Phil 1983 Dept. of Chemistry, Co-ordination Chemistry & Nagpur University Environmental Chemistry Ph.D Nagpur University "Synthesis of N-Glucosylated Formamidines" * Higher diploma 1990 Birla Institute of S & T Management, in Science & Technology & Science Instrumentation & Computer Technology Pilani Completed through official training program Title of Ph.D. Thesis:: "Organic Chemistry of Nitrogen and Sulfur Containing Compounds" synthesis of new N-Glucosylated formamidines and related compounds. Abstract: N-Glucosylated formamidines have been prepared by the Raney Nickel desulphurisation of open chain and cyclic thio systems, like thiourea, benzothiazolyl thiourea, dithiazolidines, thiosemicarbazones and Hecter's base. Awards: Junior Research Fellowship. (University Grants Commission) Senior Research Fellowship. (University Grants Commission) Institute certificate for the successful demonstration of Mefloquine process for commercialization. Institute certificate for best performer in new bio-active molecule and process, Institute certificate for personal research contribution to achieve impact factor more than 10. Post Doctoral Experience: I worked as a postdoctoral fellow ( ) with Dr. Rajender S. Varma and Dr. Keneth Bettie at DNA Technology Laboratory, HARC. The Woodland, Texas.USA. The biology work involved modification of gold, platinum, glass & polypropylene surface, attachment of linker, attachment of probe, hybridization and detection of efficiency of hybridization using phosphor imager The involves microwave assisted reactions. The solid supported microwave assisted reactions are utilized under a program "Houston Environmental Initiative."

2 Research Experience: Projects completed/ Process developed i) Mefloquine (A potent antimalarial drug): A complete innovative route with indigenous chemicals have been developed and demonstrated to industry for commercialization. ii) Carbidopa (Peripheral decorboxylase inhibitor): A process has been developed and demonstrated to industry for commercialization. iii) 2-Methyl pyrazine : It is an important intermediate for pyrazinamide (anti TB drug). iv) Verapamil (Cardiovascular drug): A cost-effective process has been developed for this drug. v) Aspartame (Peptide sweetener): A new microorganism has been found for the formation of peptide linkage. vi) Development of process for fibrinogen receptor antagonist. vii) Development of alternate route for fluvastatin iii) Development of new route for eprosarton ix) Preparation of library of 3, 5 disubstituted isoxazoles x) Synthesis of 4-aryl-3-oxo-2, 3-dihydropyridazinyl-2-acetic acids: xi) Synthesis of 6-alkyl-2-oxo 4 aryl-1, 2, 3, 4-tetrahydro-5-pyrimidine Carboxylic acids xii) Synthesis of N-Boc-4(2-phenyl acetamido)- 1,4- diazepane xiii Cyhalothrin ( pyrethroid xiv) NMITLI project on Latent M.tuberculosis Synthesis of pyridine based new molecules xv) Development of process for the synthesis of rifabutin (tuberculostatic xvi) Production of Lactic acid xvii) Synthesis of spirocyclic-fused benzopyran piperidines Xviii) Synthesis of 4-Het (aryl)-5-piperazinyl-3-(2h)-piridazinines xix) Synthesis of homopiperazine petasis amides xx) Synthesis of substituted thiazole based hydrazines and N- thiazolyl pyrazoles. Field of Interest:. 1. Process development of drugs and drug intermediates 2. Synthesis of organ metallic/ co-ordination complexes and their applications for organic reactions 3. Metal catalyzed reactions 4. Microwave assisted organic transformations 5..Solid supported reagent-catalyzed reaction 6. Modeling of ion exchange clay as an artificial enzymes 7. Development of green and economically viable processes LIST OF PUBLICATIONS 1. Raney Nickel desulphurization of 1-substituted & 1, 3- disubstituted thioureas. M. Uumar Adi, H.M.Meshram, M.P. Paranjpe. J.Indian. Chem. Soc. 62, 666, (1985). 2. Clay catalyzed facile Beckmann rearrangement of ketoximes. H.M. Meshram Synth. Commun. 20(20), 3253 (1990). 3. Dehydration of aldoximes to nitriles with clay. H.M.Meshram Synthesis 943 (1992).

3 4. Improved and convenient synthesis of disulphides in the absence of solvent catalyzed by clayfen. Harshadas Meshram Org.Prep.Proced.Int Briefs, 25, (1993). 5. An efficient and mild cleavage of thiol acetate with clayfen in the absence of solvent. Harshadas Meshram Tetrahedron Lett. 34 (15), (1993). 6. Efficient enzymatic hydrazone hydrolysis by Baker's Yeast. Ahmed Kamal, Maddamsetty v Rao and Harshadas Meshram Tetrahedron Lett. 32, 1265 (1991). 7. Enzymatic deoximation of oximes by ultrasonically stimulated Baker's yeast. Ahmed Kamal, Maddamsetty V Rao and Harshadas Meshram J. Chem. Soc., Perkin Trans. 1, 2056 (1991). 8. A facile and alternative method for the synthesis of Mefloquine. M Sureshkumar, Y V D Nageshwar and H M Meshram, Synth.Commn. 26, 1913 (1996). 9. Metalloclayzymes : An efficient oxidative coupling of thiols catalyzed by Fe(III) montmorillonite in buffer. H. M. Meshram & R Kache, Synth.Commn. 27, (1997). 10. Soild state deoximation with ammonium persulphate-silica gel: Regeneration of carbonyl compounds using microwave. R. S. Varma & H. M. Meshram Tetrahedron Lett (1997). 11. Selective oxidation of sulfide to sulfoxides and sulfones by microwave thermolysis on wet silica supported sodium periodate. R, S. Varma, R. K. Saini and H. M. Meshram Tetrahedron Lett. 38, (1997). 12. Solid state cleavage of semi carbazones and phenylhydrazones with ammonium persulphate-clay using microwave or ultrasonic irradiation. R. S.Varma and H. M. Meshram Tetrahedron Lett (1997). 13. A general synthesis of Isothiocyanates from dithiocarbamates using "claycop". H. M. Meshram, D Srinivas and J S Yadav Tetrahedron Lett. 38, (1997). 14. Clay supported ammonium nitrate "Clayan : A mild and eco-friendly reagent for dethioacetalization. H. M. Meshram, G S Reddy and J S Yadav Tetrahedron Lett. 38, (1997). 15. Clay supported ammonium nitrate "Clayan : A mild and highly selective reagent for the deoximation of electron rich oximes. H. M. Meshram, G S Reddy, D Srinivas and J S Yadav Synth. Commun. 28, , (1998). 16. Zinc promoted regioselective Friedel-Crafts' acylation of electron rich arenes. H. M. Meshram, G S Reddy, M Muralidhar Reddy and J S Yadav

4 Synth. Commun 28, 2203, (1998) 17. Zinc promoted simple and convenient synthesis of carbamates : An easy access for amide group protection. J.S.Yadav, G.S. Reddy, M. Muralidhar Reddy, H.M.Meshram. Tetrahedron Letters 39, 3259, (1998) 18. Zinc mediated facile Amide formation: Application to alkyl, aryl, hetrocyclic, carbohydrates, and amino acids. H.M.Meshram, G.S.Reddy, M.Muralidhar Reddy, and J.S.Yadav. Tetrahedron Lett. 39, 4103, (1998). 19. Clay supported ammonium nitrate Clayan : A rapid and convenient regeneration of carbonyls in dry media. H.M.Meshram, D, Srinivas, G.S.Reddy, and J.S.Yadav. Synth. Commun. 28, (1998). 20. A convenient and general synthesis of thiolesters using activated zinc. H.M.Meshram, G.S.Reddy, K. Himabindu, and J.S.Yadav. SYNLETT 1877, (1998). 21. Microwave Thermolysis VI: A rapid and general method for dethioacetalization using clay supported ammonium nitrate Clayan in dry media. H.M.Meshram, G.S.Reddy, G. Sumithra, and J.S.Yadav. Synth Commun. 29, (1999). 22. Microwave thermolysis V: a rapid and selective method for the cleavage of THP ethers, acetals and acetonides using clay supported ammonium nitrate Clayan in dry media. H.M. Meshram, G. Sumithra, G. S. Reddy, Y. S. S. Ganesh and J.S. Yadav. Synth. Commun. 29, (1999). 23. Microwave Thermolysis IX : A Selective and Rapid Oxidation of Benzylic Alcohols Using Clay Supported Ammonium Nitrate. H. M. Meshram, B. Muralidhar, G. S. Reddy, Y.S.S.Ganesh, J. S. Yadav. Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 45 (2006) 2, ; 24. Microwave Thermolysis VII: Oxidative coupling of thiol acetates and esters using Clayan in dry media. H.M.Meshram, Anis Bandyopadyaya, G.S.Reddy, and J.S.Yadav. Synth Commun. 29, 2705, (1999). 25. Microwave Thermolysis III: Coupling of 2-Naphthols in solvent free condition. H.M.Meshram, G.S.Reddy, M. M.Reddy, and J.S.Yadav. Indian J Chem B 42, 2615, (2003) 26. Clay supported ammonium nitrate Clayan : A new reagent for the selective nitration of arenes. H.M.Meshram, Y.S.S. Ganesh, and J.S.Yadav. Synth. Commun. 33, 2497, (2003) 27. Microwave Thermolysis I: A convenient and rapid coupling of thiol using Clayan in solvent free condition. H.M.Meshram, Anis Bandyopadyaya, and J.S.Yadav. Synth Commun. 29, , (1999).

5 28. Microwave Thermolysis IX: A rapid deoxygenation of sulfoxide with NaH 2 PO 2 in dry media. H.M.Meshram, Y.S.S. Ganesh, and J.S.Yadav. Indian J Chem B 44, 193 (2005) 29. Microwave Thermolysis VIII: Selective diversity in the reduction Using Sodium hypophosphite under microwave irradiation. H. M. Meshram, Y.S.S. Ganesh K. Chandra Sekhar and Yadav, J.S. Synlett,993, (2000) 30. L-selective dipeptide synthesis using novel thermophilic enzyme from chlostridium sp. J. S. Yadav, H.M. Meshram, A.R. Prasad, Y S S Ganesh,A. Bhaskar Rao, G. Seenayya, M.V. Swamy and M. Gopal Reddy. Tetrahedron Assym.12, 2505, ( 2001). 31. A practical synthesis of novel iodoquinolines: A new root for Mefloquine intermediates. Y.V.D. Nageswar, B Eshwariah, A.V. Madhavi, H. M. Meshram. Journal of molecular catalysis, 2007, 1, Clay catalyzed facile cycloaddition under microwave: Synthesis of 3-substituted benzofurans H. M. Meshram, Y.S.S. Ganesh K. Chandra Sekhar and Yadav, J.S. Synlett. 1273, (2000) 33. Zirconium (IV) chloride- mediated chemo selective conjugate addition of aliphatic amines to H.M.Meshram, C.Lakshindra, P.N.Reddy, K.Sadashiv and J.S. Yadav Synthetic commun. 36, 795 (2006). 34. A Green approach for efficient -halogenationof B-dicarbonyl compounds and cyclic ketones using N- halosccinimide in ionic liquids H.M. Meshram,P.N.Reddy,P.Vishnu,K,Sadashiv and J.S.Yadav. Tetrahedron Letter 47,991 (2006) 35. Amberlyst 15-promoted catalysed efficient halogenation of 1,3-dicarbonyl Compound and cyclic ketones using N-halosuccinimides. H. M. Meshram., P. N. Reddy, K. Sadashiv and J. S.Yadav Tetrahedron Lett 46, 623 (2005). 36. Zirconium (IV) chloride cyclization of ortho-allylphenols: Synthesis of 2-methyl 2,3- dihydrobenzofurans. H. M. Meshram, K. Premlatha, K. Ramesh Babu, B.Eeshwaraiah and J. S. Yadav. Synthetic Commun 34, 3091 (2004). 37. A Mild And Facile Procedure for The Preparation of Substituted 4- iodoquinolines H. M. Meshram, A. V. Madhavi, B. Eeshwaraiah, P. N. Reddy, Y. V. D. N. Rao and J. S. Yadav J. Molecular catalysis, 272, 57, (2007) 38. Perchloric Acid Supported on Silica Catalysed Efficient Synthesis of 1,5-Benzodiazepnes H. M. Meshram, P. N. Reddy, P. Vishnu Murthy, and J. S. Yadav Synthetic Commun 37, , Copper(II) Acetate Catalysed Mild, Highly Efficient and Practical Synthesis of Thiazoles and Amino Thaizoles and Amino Thiazoles H..M..Meshram, D. Aravind kumar and B. Ramalinga Vara Prasad. Synthetic Communications, 39, 2317, Simple and efficient Friedel-Craft alkylation of indole with electron deficient olefins promoted by Zinc acetate

6 Harshadas Mitaram Meshram*, Dachepally Aravind Kumar and Bandi Chennakesava Reddy. Helv. Chimi. Acta., 92, 1002, Triton B mediated convenient and efficient synthesis of functionlized oxime ethers H. M. Meshram*, B. Eeshwaraiah M. Sreenivas, D. Aravind, B. Syama Sundear and J.S. Yadav Synthetic Communications, 39, 1857, Triton B mediated mild, convenient and efficient method for the selective alkylation of cyclic secondary amines and thiols H. M. Meshram,* B. Chennakesava Reddy and P. Ramesh Synthetic Communications, 39, 2297, Triton B assisted efficient and convenient synthesis of 3-indolyl-3-hydroxy oxindoles in aqueous medium. H. M. Meshram,* Dachepally Aravind Kumar, B. Chennakesava Reddy and P. Ramesh Synthetic Communications, 2010, 40, Triton B mediated one-pot alkoxylation of activate Aryl / hetero aryl halides. H. M. Meshram*, P. Ramesh, B. Chennakesava Reddy and D. Aravind kumar. Synthetic Communications, 2010, 40, Efficient and Convenient PEG Mediated Synthesis of Spirooxindoles H. M. Meshram*, D. Aravind Kumar, B. R. V. Prasad, P. Ramesh. Helv. Chimi. Acta. 2010, 93, Total Synthesis of Nonenolide. H. M. Meshram*, D. Aravind Kumar, P. Ramesh. Helv. Chimi. Acta. 2010, 93, A green approach for efficient synthesis of N-substituted pyrroles in ionic liquid under microwave irradiation. H. M. Meshram*, B.R.V. Prasad, D. Aravind Kumar Tetrahedron Lett., 2010, 51, One-pot synthesis of quinoxaline-2-carboxylate derivatives using ionic liquid as reusable reaction media H. M. Meshram*, P. Ramesh, G. Santhosh Kumar and B. Chennakesava Reddy Tetrahedron Lett., 2010, 51, A mild and convenient synthesis of quinoxalines via cyclization oxidation process using DABCO as catalyst H. M. Meshram*, G. Santhosh Kumar P. Ramesh, and B. Chennakesava Reddy Tetrahedron Lett., 2010, 51, Total synthesis of ( )-diospongin A and (+)-cryptofolione via asymmetric aldol reaction H. M. Meshram*, R. Naveen Kumar. Tetrahedron Lett., 2011, 52, Concise stereoselective total synthesis of Botryolide B H. M. Meshram,* B. Chennakesava Reddy Tetrahedron Lett., 2011, 52, Total synthesis of (-)-cleistenolide H. M. Meshram*, P. Ramesh Tetrahedron Lett 2011, 52, 2443.

7 53 Bismuthtriflate Catalyzed Reaction of (N-Alkyl) Isatins with Allyltrimethylsilane H. M. Meshram*, P. Ramesh, B. Chennakesava Reddy and G. Santhosh Kumar Chemistry Lett. 2011, 40, Diastereoselective Mukaiyama Aldol Reaction of (N-alkyl) Isatins with 2- (Trimethylsilyloxy)furan by using Lanthanum triflate H. M. Meshram*, P. Ramesh, B. Chennakesava Reddy, B. Sridher and J.S.Yadav. Tetrahedron 2011, 67, Synthetic studies on cytotoxic macrolides cruentarens A and B: stereoselective synthesis of the C8 C19 segment of cruentarens A and B H..M..Meshram, B. Ramalinga Vara Prasad Tetrahedron: Asymmetry 2010, 21, DABCO promoted an efficient and convenient synthesis of benzofurans H. M. Meshram,* B.C. K. Reddy, B. R. V. Prasad, P. Ramesh, G. S. Kumar and R. N. Kumar Synthetic Communications, 2011, 42, Microwave enhanced triton B catalysed Suzuki coupling reaction H. M. Meshram*, B.R.V. Prasad, D. Aravind Kumar and B.Chennakesava Reddy I. J. Chem (accepted). 58 Boric acid promoted convenient synthesis of bis(indolyl)methane in aqueous medium H. M. Meshram*, N. Nageswara Rao, Pramod B Thakur, Bandi Chennakesava Reddy and P. Ramesh. I. J. Chem. 2013, 52B. 59 Synthesis and cytitoxicity of new quinoline derivatives H. M. Meshram*, B. C. K. Reddy, M. Kalyan, D. Aravind, P. Ramesh, M. Kavitha and J. V. Rao I. J. Chem (accepted). 60. Boric acid Mediated Mild and Efficient Friedal Craft Alkylation of Indoles with Nitro Styrenes H. M. Meshram*, N. Nageswara Rao, G. Santhosh Kumar. Synthetic Communications, 2010, 42, An efficient and environmentally friendly DABCO catalyzed Henry reaction of Isatins H. M. Meshram,* Palakuri Ramesh, A. Sanjeeva Kumar and A. Swetha Tetrahedron Letters 52 (2011) An efficient synthesis of hemiaminal of indoles by using tetrabutylammonium fluoride (TBAF) in water as a reusable reaction media Harshadas M. Meshram*, Pramod B. Thakur and Madhu B. Bejjam Green Chemistry Letters and Reviews 2012, DMF mediated Henry reaction of isatins: an efficient synthesis of 3-hydroxy-2-oxindole Harshadas M. Meshram*, Pramod B. Thakur, Madhu B. Bejjam and Vikas M. Bangade Green Chemistry Letters and Reviews 2012, An efficient and improved protocol for the N-arylation of N-heteroaryls using Ionic liquid as a reraction media H. M. Meshram, B. Chennakesava Reddy, Palakuri Ramesh and N. Nageswara Rao Der Pharma Chemica 2012, 4, Microwave assisted catalyst free synthesis of 3-hydroxy-2-oxidoles by aldol condensation of acetophenones with isatins H. M. Meshram, N. Nageswara Rao, N. Satish Kumar and L. Chandrasekhar Der Pharma Chemica 2012, 4, Catalyst-free four-component protocol for the synthesis of substituted pyrroles under reusable reaction media H. M. Meshram, B. Madhu Babu, G. Santosh Kumar, Pramod B. Thakur, Vikas M. Bangade

8 Tetrahedron Letters 2013, 54, First stereoselective total synthesis of Phomolide G and H via RCM protocol Palakuri Ramesh, B. Chennakesava Reddy, H.M. Meshram Tetrahedron Lett. 2012, 53, Synthesis and cytotoxicity of new quinoline derivatives H. M. Meshram*, B. C. K. Reddy, M. Kalyan, D. Aravind, P. Ramesh, M. Kavitha and J. V. Rao Indian Journal of Chemistry, Sec B, 2012, 51B, Boric acid promoted an efficient and practical synthesis of fused pyrimidines in aqueous media H. M. Meshram, A. Sanjeeva Kumar, G. Santosh Kumar, A. Swetha, B Chennakesava Reddy and P. Ramesh Der Pharma Chemica, 2012, 4, Stereoselective total synthesis of Multiplolide A and its Diastereomer B. Chennakesava Reddy, Vikas M Bangade, P. Ramesh and H. M. Meshram; Helvetica Chemica Acta 2013, 96, First stereoselective total synthesis of Phomolide G and H via RCM protocol P. Ramesh, B. Chennakesava Reddy and H. M. Meshram Tetrahedron Lett. 2012, 53, An efficient total synthesis of ( )-Anamarine P. Ramesh and H. M. Meshram; Tetrahedron Lett. 2012, 53, First total synthesis of Salinipyrone A using highly Stereoselective Vinylogous Mukaiyama aldol reaction P. Ramesh and Harshadas Mitaram Meshram Tetrahedron 2012, 68, Convenient and simple synthesis of 2-aminothiazoles by the reaction of α-halo ketone carbonyls with ammonium thiocyanate in the presence of N-methylimidazole H. M. Meshram, Pramod B. Thakur, B. Madhu Babu, Vikas M. Bangade Tetrahedron Letters 2012, 53, A convenient, rapid, and general synthesis of α-oxo thiocyanates using clay supported ammonium thiocyanate H. M. Meshram, Pramod B. Thakur, B. Madhu Babu, Vikas M. Bangade Tetrahedron Letters 2012, 53, 1780.(Cit.-2) 76. Microwave assisted catalyst-free synthesis of azaarene-substituted 3-hydroxy-2-oxindoles by the functionalization of sp 3 C H bond in methyl pyridine. H. M. Meshram, N. Nageswara Rao, L. Chandrasekhara Rao, N. Satish Kumar Tetrahedron Letters 2012, 53, Boric acid promoted convenient synthesis of bis(indolyl)methane in aqueous medium H. M. Meshram*, N. Nageswara Rao, L.C, Rao, B.Chennakesava Reddy and P. Ramesh. Indian J. Chem (accepted). 78. Microwave enhanced triton B catalysed Suzuki coupling reaction H. M. Meshram*, B.R.V. Prasad, D. Aravind Kumar and B.Chennakesava Reddy Indian J. Chem (accepted). 79. DABCO promoted an efficient and convenient synthesis of benzofurans H. M. Meshram,* B.C. K. Reddy, B. R. V. Prasad, P. Ramesh, G. S. Kumar and R. N. Kumar Synthetic Commun., 2012, 42, An efficient and environmentally friendly DABCO catalyzed Henry reaction of Isatins H. M. Meshram, P. Ramesh, A. Sanjeeva Kumar and A. Swetha; Tetrahedron Lett, 2011, 52, 2443.

9 Diastereoselective Mukaiyama Aldol Reaction of (N-alkyl) Isatins with 2- (Trimethylsilyloxy)furan by using Lanthanum triflate H. M. Meshram*, P. Ramesh, B. Chennakesava Reddy, B. Sridher and J.S.Yadav. Tetrahedron 2011, 67, Bismuthtriflate Catalyzed Reaction of (N-Alkyl) Isatins with Allyltrimethylsilane H. M. Meshram*, P. Ramesh, B. Chennakesava Reddy and G. Santhosh Kumar Chemistry Lett. 2011, 40, Total synthesis of (-)-cleistenolide H. M. Meshram*, P. Ramesh Tetrahedron Lett., 2011, 52, Concise stereoselective total synthesis of Botryolide B H. M. Meshram,* B. Chennakesava Reddy Tetrahedron Lett., 2011, 52, Total synthesis of ( )-diospongin A and (+)-cryptofolione via asymmetric aldol reaction H. M. Meshram*, R. Naveen Kumar. Tetrahedron Lett., 2011, 52, Microwave promoted catalyst-free benzylic C H functionalization of methyl quinoline and Michael addition to beta-nitro styrene N. Nageswara Rao, H.M. Meshram Tetrahedron Lett., 2013, 54, Microwave assisted water mediated benzylic C H functionalization of methyl aza-arenes and nucleophilic addition to aromatic aldehydes N. Nageswara Rao, H.M. Meshram Tetrahedron Lett., 2013, 54, Catalyst free Michael addition Of 3- methyl-2-pyrazolin-5-one to β-nitrostyrenes on water : A green protocol for facile synthesis of 4-(1-aryl-2-nitroethyl)-3-methyl-1H-pyrazol-5-ol H.M. Meshram, Nandigama Satish Kumar, Jagadeesh Babu Nanubolu, L. Chandrasekhara Rao, N. Nageswara Rao Tetrahedron Lett., 2013, 54, 88. DABCO catalyzed highly regioselective synthesis of fused imidazo-heterocycles in aqueous medium Vikas M. Bangade, B. Chennakesava Reddy, Pramod B. Thakur, B. Madhu Babu, H.M. Meshram Tetrahedron Lett., 2013, 54, Catalyst-free synthesis of 3-hydroxy-3-(alkyl/aryl)indolin-2-ones by addition of organoaluminum reagents to isatins 90. G. Santosh Kumar, Palakuri Ramesh, A. Sanjeeva Kumar, A. Swetha, H.M. Meshram Tetrahedron Lett., 2013, 54, PATENTS: Process for the preparation of 4-bromo or 4-iodo 2, 8,-bis (trifloromethyl) quinoline. Nageswar, Y.V.D.; Meshram, H.M.; Sattur, P.B. Pat No: , Appl No: 1043/Del/89. Date: 10/11/89. Improved process for the preparation of a 2-pyridyl-2, 8-bis (trifloromethyl)-4-quinoline methanol. Nageswar, Y.V.D.; Meshram, H.M.; Sattur, P.B. Pat No: , Appl No: 1044/Del/89. Improved process for the preparation of mefloquine hydrochloride. Nageswar, Y.V.D.; Meshram, H.M.; Sattur, P.B. Pat No: , Appl No: 1045/Del/89. Process for the preparation of 4-cyano 2,8,-bis-(trifloromethyl) quinoline. Nageswar, Y.V.D.; Meshram, H.M.; Prasad, A.R.; Sattur, P.B. Pat No: , Appl No: 1099/Del/89. Process for the preparation of 4-pyridyl- 2,8-bis(trifloromethyl) 4quinolyl ketone.

10 Nageswar, Y.V.D.; Meshram, H.M.; Prasad, A.R.; Hashim, S.R.; Sattur, P.B. Pat No: , Appl No: 1101/Del/89. Improved process for the preparation of mefloquine hydrochloride. Nageswar, Y.V.D.; Meshram, H.M.; Prasad, A.R.; Hashim, S.R.; Sattur, P.B. Pat No: , Appl No: 1102/Del/89. Improved process for the preparation of mefloquine hydrochloride. Nageswar, Y.V.D.; Meshram, H.M.; Prasad, A.R.; Hashim, S.R.; Sattur, P.B. Pat No: , Appl No: 1103/Del/89. Process for the preparation of 4-tosyloxy-2, 8-bis (trifloromethyl) quinoline. Nageswar, Y.V.D.; Meshram, H.M.; Sattur, P.B. Pat No: , Appl No: 1071/Del/89. Enzymatic process for the preparation of aspartame. Yadav, J.S.; Bhaskar Rao, A.; Meshram, H.M. and Prasad, A.R. 548/Del/99, Appl: An improved process for the selective acylation of electron rich arenes using transition metals powder. Yadav, J.S.; Meshram, H.M. Reddy, G.S. and Reddy, M.M. 274/Del/99, Appl: An improved process for the preparation of amides using transition metals powder. Yadav, J.S.; Meshram, H.M. Reddy, G.S. and Reddy, M.M. 3827/Del/98, Appl: An improved process for the preparation of α-acyl substituted using transition metals powder. Yadav, J.S.; Meshram, H.M. Reddy, G.S. Reddy, M.M. 3828/Del/99, Appl: An improved process for the preparation of crabmeats using transition metals powder. Yadav, J.S.; Meshram, H.M. Reddy, G.S. 276/Del/99, Appl: A process for the nitration of arenes using a new catalyst. Meshram, H.M.; Ganesh, Y.S.S. and Yadav, J.S.56/Del/99, Appl: 12/1/1999. An improved process for the preparation of unsymmetrical carbonates. Yadav, J.S. Meshram, H.M. Reddy, G.S. and Reddy, M.M. (patents: applied, 1998) An improved process for the preparation of aromatic bromo compounds. Meshram, H.M.; Reddy, M. M.; Ganesh, Y. S. S. and Yadav, J.S. 66/ Del/ 99. Appl: A New sorce of thermophilic enzyme for the preparation of dipeptides. Bhaskar Rao, A.; Meshram, H.M., Ganesh, Y.S.S. Yadav, J.S.; Reddy, G.; Sinayya, G. 544/Del/99. Appl: An improved Synthesis for α-bromination of sulphonamide substituted Aryl-Alkyl ketones H. M. Meshram, Y. S. S. Ganesh, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; Indian patent No: , Date of grant 19/01/2009. Process for Synthesis of Bis(subtituted-4-Quinolyl) H. M. Meshram, K. Premalatha, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; US Patent No: , Date of grant 17/08/2004. Process for Synthesis of Bis(subtituted-4-Quinolyl) H. M. Meshram, K. Premalatha, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; Japan Patent No: , Date of grant 23/10/2009.

11 Process for Synthesis of Bis(subtituted-4-Quinolyl) H. M. Meshram, K. Premalatha, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; Germany Patent No: DE B4, Date of grant 07/12/2006. Process for Synthesis of Bis(subtituted-4-Quinolyl) H. M. Meshram, K. Premalatha, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; South Africa Patent No: 2005/7913, Date of grant 25/10/2006. Process for Synthesis of Bis(subtituted-4-Quinolyl) H. M. Meshram, K. Premalatha, A. V. Madhavi, B. Eshwaraiah and J. S. Yadav; Indian Patent No : , Date of grant 23/01/2009. An improved process for the enhancement of cycle-life of the Zinc-Chromium based catalysts use in the synthesis of 2-methylpyrazine. P S Sai Prasad,K V Raghavan,P Kantha Rao,S J Kulkarni,K Narasimha Rao,R Gopinath,S Farsinavis, H M Meshram US /27/03/01 PCT/IN01/00069/30/3/01 Book Chapter: A chapter entitled Heterogenized Reactions for Green Chemistry is written in green chemistry book J. S. Yadav, H. M. Meshram, Y. S. S. Ganesh (2000) 2. Recent Organic Transformations in Ionic Liquids. J.S.Yadav*, H.M.Meshram, B.Eeshwaraiah (2004)