Chemical Management Manual. Ver. 1

Transcription

1 Chemical Management Manual Ver. 1 Okinawa Institute of Science and Technology Graduate University Research Safety Section, Division of Research Support March 2013

2 About the Chemical Management Manual This manual is prepared in line with the contents of the Rules for the Management of Chemical Materials and Rules for Poisonous and Deleterious Substances Management, and is intended to be a comprehensive explanation of the necessary procedures concerning the handling of chemical materials. Please utilize the manual in accordance with your intended purpose. Furthermore, the items indicated below are exempt from the management set out in this manual. Please contact the Research Safety Section or the nominated relevant sections regarding the handling of these types of materials. Narcotics, psychotropic drugs, etc. Management shall be implemented according to the Rules for the Management of Narcotics, etc. and Manual of Narcotics and Psychotropic Drugs that are now under preparation. Please contact Research Safety Section should you have any questions. Nuclear fuel material Management shall be implemented according to the Rules for the Management of Metrics. Please contact Research Safety Section should you have any questions. Radioisotopes (RI) Management shall be implemented according to the Rules for the Prevention of Radiation Hazards and Manual of Radioisotope Experiment. Please contact Research Safety Section should you have any questions. Contact point for matters related to the safe management of chemicals and this manual: Research Safety Section: research_safety@oist.jp

3 Manual for the Handling of Chemical Materials Contents 1. BASICS ABOUT MANAGEMENT OF CHEMICAL MATERIALS TYPES OF CHEMICAL MATERIALS AND OBLIGATIONS WHEN USING THEM SPECIFIED CHEMICAL MATERIALS/ORGANIC SOLVENTS POISONOUS AND DELETERIOUS SUBSTANCES HAZARDOUS MATERIALS CLASS 1 AND CLASS 2 CHEMICAL MATERIALS HIGH-PRESSURE GAS PRECAUTIONS FOR HANDLING CHEMICAL MATERIALS BEFORE USE IN OPERATION AFTER USE EMERGENCY MEASURES AGAINST ACCIDENTS OR DISASTER... 18

4 Manual for the Handling of Chemical Materials Additional Information provided in the Manual Chemical Risk Information Platform 20 Rules for the Management of Chemical Materials 21 Rules for Poisonous and Deleterious Substances Management 29 List of Specified Chemical Substances (Labour Safety and Health Act) 56 List of Organic Solvents (Labour Safety and Health Act) 58 List of Poisonous Substances (Poisonous and Deleterious Substances Control Act) 60 List of Specified Poisonous Substances (Poisonous and Deleterious Substances Control Act) 66 List of Deleterious Substances (Poisonous and Deleterious Substances Control Act) 67 List of Hazardous Materials (Fire Defense Act) 90 List of Class 1 Chemical Materials (PRTR Act) 96 List of Class 2 Chemical Materials (PRTR Act) 121

5 Manual for the Handling of Chemical Materials 1. Basics about Management of Chemical Materials Research activities involve the necessary handling of a wide range of different chemical materials, with a wide range of properties and associated risks. Handling chemical materials in the absence of knowledge and awareness of their properties is very dangerous and may lead to serious accidents, such as ignition and explosion, or leakage of hazardous materials, and these may affect both the user and those around you. The handling of chemical materials is regulated by various laws including the Industrial Safety and Health Act and Poisonous and Deleterious Substances Control Act, and a unified management system that extends from the obtainment of such materials through to their use, their storage, and their disposal is required. Experimenters should work on a routine basis to properly understand the risks of each chemical material and to plan and implement a safe experiment. OIST stipulates procedures for the handling of chemical materials in the Rules for the Management of Chemical Materials and Rules for Poisonous and Deleterious Substances Management. The Research Safety Section will take a pivotal role in managing practical affairs. All activities handling chemical materials shall be performed in compliance with the above Acts and Rules and in according to the instructions of the Chemical Materials Safety Manager (FACULTY or Section Leader). If you are at all unclear about anything pertaining to chemical handling and management, please do not hesitate to contact the Research Safety Section. 1

6 Manual for the Handling of Chemical Materials 2. Types of Chemical Materials and Obligations When Using Them The types of chemical materials specified in the Rules for the Management of Chemical Materials are as follows. (1) Specified chemical materials (2) Organic solvents (3) Poisonous materials (4) Deleterious materials (5) Specified poisons (6) Hazardous materials (7) Class 1 chemical materials (8) Class 2 chemical materials (9) High-pressure gas (10) Volatile organic compounds (VOC) (11) Specified offensive odor substances (12) Specific substances, Designated substances, Class1 materials and Organic chemicals (13) Agrochemicals (14) Chemical herbicides (15) Explosives (16) Chemically/biologically harmful and hazardous materials besides those listed in (1) to (15) above. (17) Wastes produced as a result of the use of any of materials listed in (1) to (16) above. In the list above, the chemicals shown in RED are frequently used at OIST. This Chapter will describe the use of those materials. *A list of chemical materials and the statutory provisions regarding their use are available at the end of this manual and from the Research Safety Section website at: 2

7 Manual for the Handling of Chemical Materials 2.1.Specified Chemical Materials/Organic Solvents These materials are described in the Industrial Safety and Health Act as those likely to be hazardous to health upon exposure. Specified chemical substances, etc. Chlorinated Biphenyls, Acrylamide, Hydrogen fluoride, etc. (List: P.40-41) Organic solvents Acetone, Toluene, Methanol, etc. (List: P.42-43) Any chemical material named in these lists must be handled in conformity to the following: Use Specified Chemical Materials/Organic Solvents in a local ventilation system such as a fume hood: In order to prevent exposure of the experimenter and the people around, these materials must only be used inside a local ventilation system. (See P for the use of local ventilation systems.) Also, keep in mind that some of the chemical materials, such as perchlorates and explosive materials, can only be used in a specially dedicated local ventilation system. Monitor the working environment twice a year: The Research Safety Section will measure the air concentration of such chemicals during your experiment in a laboratory. The Research Safety Section will notify you of the measurement in advance, and we ask for your patience and OIST. Receive a special medical examination twice a year: To ascertain that no damage to health has occured, you must periodically undergo a special medical examination. All persons who handle Class 1 and 2 Specified chemical materials and organic solvents must receive such an examination; the specific items to be examined depend on the materials being handled. These examinations provided by the OIST Health Center, and applicable persons are required to follow instructions of the Health Center. 3

8 Manual for the Handling of Chemical Materials 2.2.Poisonous and Deleterious Substances Materials with poisonous/deleterious properties are provided for in the Poisonous and Deleterious Substances Control Act. Classifications are designated by the Ministry of Health, Labour and Welfare, and some of the indicators for the criteria used in such classifications are as follows: Poisonous materials Lethal dose for a general adult male is 2g or less: Mercury, Arsenic, Sodium cyanide, etc. (List: P.44-49) Specified poisonous materials Of the above materials, those that are extremely poisonous or widely used: Tetraalkyl lead, Monofluoroacetate, etc. (List: P.50) Deleterious materials Lethal dose for a general adult male is 2g to 20g, or extreme irritants: Ammonia, Sodium peroxide, Ethyl acetate, etc. (List: P.51-73) In OIST, these substances are managed in accordance with with the Rules for Poisonous and Deleterious Substances Management (P.30-39). < Unit-level management of poisonous and deleterious substances > Chief Manager of Poisonous and Deleterious Substances (Faculty or Section Leader) Responsible for management related to the handling of poisonous and deleterious materials in the unit (application, purchase, storage, handling, disposal, etc.); Appoints a poisonous and deleterious substances manager (as necessary) When a Substances Manager is appointed or changed, submit Report on the Appointment of or change in the Assistant (P.36) to the Research Safety Section. Manages keys of storage cabinets of poisonous and deleterious materials. Poisonous and Deleterious Substances Assistant (Selected from unit members) Assists duties of the Chief Manager of Substances. Unit members In accordance with instructions provided by the Chief Manager and manager, endeavor to manage and use nominated materials appropriately. 4

9 Manual for the Handling of Chemical Materials < Obtaining poisonous and deleterious substances > Acquisition or Bringing-in Upon completion of the activity, fill in necessary items in a prescribed form (P.38) and submit the form to the Research Safety Section without delay. 5

10 Manual for the Handling of Chemical Materials < Storage of poisonous and deleterious substances > Poisonous and deleterious substances should be labeled either 医薬用外毒物 (Poisonous substance not intended for medical purposes), or 医薬用劇物 (Deleterious substance not intended for medical purposes), as applicable, and stored in a lockable and unbreakable special-purpose cabinet with lock (do not use those having glass doors). Cabinets for storing poisonous and deleterious substances shall be locked at all times (cabinet keys shall be controlled by the Chief Manager or the Manager). Poisonous Substance Not intended for medical purposes Deleterious Substance Not intended for medical purposes < Relocation or transfer of poisonous and deleterious substances > When a storage site is changed, a Report on Transfer of Substances (P.39) shall be submitted to the Research Safety Section promptly. When ownership of poisonous and deleterious substances is transferred to another unit in the Corporation, a Report on Transfer of Substances (P.39) shall be submitted to the Research Safety Section promptly. 6

11 Manual for the Handling of Chemical Materials < Handling of Specified Poisonous Substances > When using Specified Poisonous Substances, special procedures must be followed. Contact the Research Safety Section before obtaining such substances. < Summary of Notification Forms to be Submitted > All necessary notification forms must be submitted promptly to the Research Safety Section. For information on the specific procedures, see the Rules for Poisonous and Deleterious Substances Management attached at the end of this manual. Cases That Require Forms Forms to Be Submitted Appointment or change of a Substances Assistant Report on Appointment of Substances Assistant Use of specified poisonous substances, Modification of registered researcher handling specified poisonous substances Application for Specified Poisons Researcher Acquisition of poisonous and deleterious substances Report on Acquisition of Substances Transfer of poisonous and deleterious substances Report on Transfer of Substances 7

12 Manual for the Handling of Chemical Materials 2.3.Hazardous Materials Materials that are flammable or explosive are controlled by the Fire Defense Act, and are classified into 6 types (see P.74-79): Type 1: Solid oxide (Sodium perchlorate, Sodium nitrate, etc.) Type 2: Flammable solid (Sulfur, Magnesium, etc.) Type 3: Pyrophoric substance and Dangerous when Wet (Potassium, Sodium, etc.) Type 4: Flammable liquid (Acetaldehyde, Methanol, Ethanol, etc.) Type 5: Self-reactive substances (Trinitrotoluene, Azobenzene, etc.) Type 6: Liquid oxide (Perchloric acid, Nitric acid, etc.) Each of these types is further classified into several classes, with an amount of assignment, i.e., the allowable amount, specified for each class (see P.74-79). Rules control the amount of each material that may be stored in one room. The ratio of the amount of each dangerous material stored compared to the amount of assignment must be calculated. When the total of these ratios for all dangerous materials stored in one room is 1 or more, permission of the Fire Fighting Head Office controlling the area is required. When the ratio total is 0.2 or more, a the Fire Department must be notified. The Research Safety Section submits this notification as necessary on the basis of data submitted by research units. When you need to purchase a large amount of listed materials, please contact the Research Safety Section in advance. The Research Safety Section will respond to you with a judgment as to whether or not the above formal requirement is applicable in each case. 8

13 Manual for the Handling of Chemical Materials 2.4.Class 1 and Class 2 Chemical Materials These materials are stipulated in the Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof (PRTR Act) as chemical materials which are suspected to be hazardous to the environment and human body. If Class 1 chemical materials (P ) are released into the environment (such as air, water and soil), the location and the amount of material released and the removal and transfer of waste materials (the transfer amount), must be confirmed, and this information must then be aggregated and made public. Examples of Class 1 Chemical Substances Volatile hydrocarbon Organochlorine Compounds Agricultural chemicals Metal compounds Ozone depleting substances Others Benzene, toluene, xylene, etc. Dioxins, trichloroethylene, etc. Methyl bromide, fenitrothion, chlorpyrifos, etc. Lead and compounds thereof, organic tin compounds, etc. CFC, HCFC, etc. Asbestos, etc. When the total amount of the listed materials possessed in the whole place of business becomes equal to or exceeds the amount designated (depending on the type of business), submission of report becomes obligatory. As of March 2010, such regulatory control is not applicable to OIST, but in the future, as the business expands, it may become applicable to OIST. The Research Safety Section carries out an investigation on the amount of such materials in the possession of OIST once a year. 9

14 Manual for the Handling of Chemical Materials 2.5.High-pressure Gas High-pressure gas is subject to regulatory control based on the High Pressure Gas Safety Act. < Gas cylinders > Mind the following points when handling: Put a safety cap on the gas cylinder when relocating, and use a cylinder carrier Gas cylinders are very heavy. If one inadvertently falls over as it is moved, there is a considerable risk of injury. Avoid falls by using the correct cylinder carrier. Always use a safety cap in order to avoid rapid release of the contents due to a fall, which may result in oxygen deficiency or poisoning. Avoid direct sunlight and install in a well-ventilated place When a gas cylinder is installed in a place exposed to direct sunlight or close to a heat source, the internal temperature of the cylinder will rise, which may result in breakage of the safety valve. Secure to a metal rack at both the top and bottom of the gas cylinder using specifically designed chains (secure the rack as well). As a gas cylinder is heavy and has a high center of gravity, it can easily fall over unless mounted securely. An overturned gas cylinder poses a great risk of damage to nearby objects, or more seriously, to the cylinder s valve, with consequent dangerous leakage of high-pressure gas. When using high-pressure gas, bear in mind the risk of injury due to a valve breakage or a blown-away valve, and follow the precautions below: Before operating a valve, receive guidance from a person who is familiar with the operation. When opening or closing a valve, use a prescribed wrench. When opening a valve, do it calmly and slowly. When closing, be sure to close the valve completely. Do not operate in a position directly in front of a decompression valve or a pressure meter. Consult the Facilities Operation & Use Section for determination of installation site in advance. 10

15 Manual for the Handling of Chemical Materials < Liquid nitrogen > When using liquid nitrogen, pump it from the storage tank room for each use. To avoid the risk of oxygen deficiency or frostbite when handling liquid nitrogen, follow the precautions below: Keep the room well-ventilated when handling liquid nitrogen inside the building A room filled with nitrogen gas causes oxygen deficiency, a serious danger to workers. Be sure to check the ventilation condition in the room before using or storing liquid nitrogen. Use gloves (leather gloves, etc.) when handling liquid nitrogen When touching low-temperature items or containers, be sure to wear leather gloves or prescribed gloves. Avoid fabric gloves (cotton work gloves, etc.), as they absorb liquid, resulting in a danger to workers When frostbite occurs Warm up the injured part of the body with warm water (as a first aid measure), while avoiding direct contact with the injured part. Then, seek prompt treatment by a physician. Create a release outlet on all containers for liquid nitrogen An increase in internal pressure of container is highly dangerous, as it may result in explosion. Do not seal storage containers air-tight, and always create a release outlet for gas (nitrogen) to escape. Management of liquid nitrogen is carried out by the Facilities Operation & Use Section.When pumping, follow the instructions provided by the Facilities Operation & Use Section. 11

16 Manual for the Handling of Chemical Materials 3. Precautions for Handling Chemical Materials 3.1.Before Use < Education and Training > Be sure to participate in a training session on chemical materials (conducted by the Research Safety Section) before handling any dangerous materials. Training sessions carried out by the Research Safety Section provide only general precautions in the handling of chemical materials. Therefore, there must be a further training session designed for each experiment. Each of the Faculty or Section Leaders must provide guidance on the following matters before any of your members starting experiments: - Possible hazards related to reagents to be used - First aid and emergency measures for reagents in the eyes or on the skin - How to use relevant instruments and equipment - Laboratory protocols regarding the method to be used - Protective equipment applicable to the instrument or method Personnel who engage in experiments must act in conformity to the guidance provided and endeavor to work safely. 12

17 Manual for the Handling of Chemical Materials < Obtaining chemical materials > Limit the amount of chemical materials obtained (purchased, acquired or brought in) within the extent necessary for the work. Prior to each use, be sure to check the descriptions in the applicable MSDS (Chemical Material Safety Data Sheet) and confirm the physicochemical property and hazardous nature of the material to be used and methods of disposal thereof, etc. Obtain information from printed materials attached to the reagent purchased, the Chemical Risk Information Platform (see P.20), etc. *MSDS: Material Safety Data Sheet, which describes information necessary for the safe handling of chemicals and ingredients containing chemicals, etc. Items described in MSDS (according to JIS Z7250:2005) 1. Chemical materials, etc. and company information 2. Summary of information on hazardous and toxicological natures 3. Composition and information on ingredients 4. First aid measures 5. Fire fighting measures 6. Accidental release measures 7. Handling and storage precautions 8. Exposure controls and personal protection 9. Physical and chemical properties 10. Stability and reactivity 11. Hazardousness information 12. Ecological impact information 13. Disposal precautions 14. Transport precautions 15. Relevant laws and regulations 16. Other information In addition to the information on matters concerning handling methods of chemical materials, be sure to check 15. Relevant laws and regulations applicable to the work. In cases where matters described on P.3-11 are applicable, follow the description in this manual in respect use or management of chemical materials. In cases where statutory provisions other than the Acts listed above apply, contact the Research Safety Section prior to the commencement of the use. 13

18 Manual for the Handling of Chemical Materials 3.2.In Operation Errors in the handling of hazardous substances may have adverse effects not only to the health of the handler but also other people around and may also damage the environment. Each person must be aware that they are handling hazardous substances and handle them appropriately. In particular, bear in mind the following points: Secure enough experimental space: Working in a narrow space may result in equipment being knocked over and contamination with chemical materials. Keep your working area tidy and organized at all times. Make clear the owner and type of reagents: Describe unit name, etc. on the container of reagent, laboratory instruments, etc. Also, clearly label the type of reagents, by placing the name of the reagent on the tube or affixing an appropriate label, so that errors during experiment can be prevented. 14

19 Manual for the Handling of Chemical Materials Use a fume hood when handling highly volatile substances such as organic solvents: In order to prevent exposure, the handling of highly volatile substances must be carried out using a fume hood. Keep in mind the following points for operation of a fume hood. If any abnormality is found, stop experiment and contact the Facilities Operation & Use Section and the Research Safety Section. 1. Make sure if the machine operates normally before working with it. Hold a piece of paper or plastic in the airstream to see if enough airflow is provided. 2. Adjust the sash height and keep an appropriate posture for the operation. Air flow may be decreased in some types of local ventilation system when the sash is wide open. However, if the sash height is too low, it may interfere with correct operation. Adjust the height to be appropriate for the operation. In addition, keep your head outside of the sash, so as not to inhale hazardous substances. Make sure that you work using the correct posture. 15

20 Manual for the Handling of Chemical Materials 3. Do not bring unnecessary materials into the fume hood. Materials placed inside the fume hood may adversely affect air intake, resulting in decrease in draft air. Reagents, etc., left inside the fume hood may result in the leak of hazardous substances when the fan is turned off. Bring only items essential to the experiment into the fume hood. 4. When a chemical spill occurs, handle the spill right away. Chemical spills increase the chances of exposure to hazardous substances, contamination of instruments, etc. Even though it is inside a fume hood, any chemical spill must be treated right away. Use the spill kit available at the emergency box located in each lab area. 5. Do not stop operation of the fume hood during preparation and cleaning-up. Volatilization of hazardous materials is not limited to the period of the actual experiment. Keep operating the fume hood even during preparation and cleaning-up. 16

21 Manual for the Handling of Chemical Materials 3.3.After Use < Use log/record > Keep a log of the amount of poisonous substances used at the end of each use. For deleterious substances, keep a log of each use or when all material is used up. For working environment monitoring, the amount of organic solvents and specified chemical materials used may need to be recorded for each use, depending on instruction by the Labour Standards Inspection Office. Necessary information regarding these instructions will be provided by the Research Safety Section. < Storage of reagents > Return the reagents to the place where they were originally stored after finishing with them. To prevent theft or other loss, do not leave reagents unattended on the bench. In addition, to prevent chemical materials from leaking if they fall over in storage, apply fall-prevention measures such as placing them in or on a reagent tray. Use a dedicated storage cabinet for poisonous and deleterious substances. When all materials are stored, lock the storage cabinet. 17

22 Manual for the Handling of Chemical Materials 4. Emergency Measures against Accidents or Disaster If any of the following occur, immediately contact: Security Control Center(Tel: 18861) Manager of Research Safety Section(Tel: 12385) Chemical Materials Safety Officer(Tel: 12358) If any person is injured, give top priority to an ambulance request. In the event of Fire: If there is anyone around the area, give warning of fire breakout with a loud voice. If the fire is still in the early stages and it is possible to do so, extinguish the fire. If the fire reaches the ceiling, do not attempt to extinguish and evacuate from the area immediately. Earthquake: Make sure that no one remains or is trapped, and evacuate the area. Other accidents during experiment, etc. Take measures to prevent a secondary disaster to the possible extent (such as removal of possible hazards from the device and stop of the chemical leakage so as not to cause a further spread), and evacuate from the area. Confirm the following items, in order to act safely and promptly under emergency situations: Evacuation routes Trace the evacuation routes (at least two routes), and confirm the locations of emergency doors and evacuation sites. Disaster prevention equipment, etc Confirm the locations of fire extinguishers or fire hydrants, fire alarms, etc. as well as their methods of use. Emergency contacts In case of emergency situations such as accidents or acute diseases, maintain a list for your section of emergency contacts such as home numbers. 18

23 Manual for the Handling of Chemical Materials Additional Information provided in the Manual Chemical Risk Information Platform 20 Rules for the Management of Chemical Materials 21 Rules for Poisonous and Deleterious Substances Management 29 List of Specified Chemical Substances (Labour Safety and Health Act) 56 List of Organic Solvents (Labour Safety and Health Act) 58 List of Poisonous Substances (Poisonous and Deleterious Substances Control Act) 60 List of Specified Poisonous Substances (Poisonous and Deleterious Substances Control Act) 66 List of Deleterious Substances (Poisonous and Deleterious Substances Control Act) 67 List of Hazardous Materials (Fire Defense Act) 90 List of Class 1 Chemical Materials (PRTR Act) 96 List of Class 2 Chemical Materials (PRTR Act)

24 Chemical Risk Information Platform Chemical materials are controlled in several different regulatory frameworks, and the uses of poisonous and deleterious substances and PRTR related materials, in particular, are subject to several duties such as taking a use log for the amount of use and submission of reports. Chemical Risk Information Platform is a publicly available means for easily collecting information on regulatory controls in Japan and oversea countries and chemical risks and is accessible at the following URL. (It is also accessible from chemical materials at Research Safety Section website.) For each of chemical materials, the following information can be obtained: - Information on regulatory controls in Japan and oversea countries - Biological concentration - Permissible concentration for safe working - Risk information - Adverse effect on health, etc. Please note that some of the information is provided in Japanese only. 20

25 OIST Graduate University Rules for the Management of Chemical Materials 沖縄科学技術大学院大学化学物質管理規程 (Version 1.00, February 28, 2013) ( 平成 25 年 2 月 28 日第 1.00 版 ) (Purpose 目的 ) Article 1 第 1 条 These Rules set forth the necessary matters for the proper use and management of Chemical Materials at OIST Graduate University (hereinafter referred to as University ). この規程は 沖縄科学技術大学院大学 ( 以下 本学 という ) において 化学物質が適正に使用及び管理されるために必要な事項を定める (Definitions of Terms 定義 ) Article 2 第 2 条 1 As used in these Rules, the following definitions apply: 本規程において用いる用語の定義は 次の各号に定めるところによる (1) Chemical Materials means elements and compounds employed for education or research. 化学物質 とは 教育又は研究に用いる元素及び化合物をいう (2) Controlled Substances means any of the following: 規制物質 とは 次の各号に掲げるものをいう a Specified Chemical Substances as listed in Appendix 3 of the Enforcement Order of the Industrial Safety and Health Act (Cabinet Order No. 318 of 1972). 特定化学物質労働安全衛生法施行令 ( 昭和 47 年政令第 318 号 ) 別表第 3 に掲げるもの b Organic Solvents as listed in Appendix 6-2 of the Enforcement Order of the Industrial Safety and Health Act. 有機溶剤労働安全衛生法施行令別表第 6 の 2 に掲げるもの c Poisonous Substances as listed in Appendix 1 of the Poisonous and Deleterious Substances Control Act (Act No. 303 of 1950) and in Article 1 of the Designation Order for Poisonous and Deleterious Substances (Cabinet Order No. 2 of 1965), excluding drugs and quasi-drugs. 毒物毒物及び劇物取締法 ( 昭和 25 年法律第 303 号 ) 別表第 1 及び毒物及び劇物指定令 ( 昭和 40 年政令第 2 号 ) 第 1 条に掲げるものであって 医薬品及び医薬部外品以外のもの d Deleterious Substances as listed in Appendix 2 of the Poisonous and Deleterious Substances Control Act and in Article 2 of the Designation Order for Poisonous and Deleterious Substances, excluding drugs and quasi-drugs. 劇物毒物及び劇物取締法別表第 2 及び毒物及び劇物指定令第 2 条に掲げるものであって 医薬品及び医薬部外品以外のもの 1 21

26 e Specified Poisons as listed in Appendix 3 of the Poisonous and Deleterious Substances Control Act and in Article 3 of the Designation Order for Poisonous and Deleterious Substances, excluding drugs and quasi-drugs. 特定毒物毒物及び劇物取締法別表第 3 及び毒物及び劇物指定令第 3 条に掲げるものであって 医薬品及び医薬部外品以外のもの f Hazardous Materials as listed under the Items column in the table of Appendix 1 of the Fire Service Act (Act No. 186 of 1948). 危険物消防法 ( 昭和 23 年法律第 186 号 ) 別表第 1 の品名欄に掲げるもの g Class 1 Designated Chemical Substances as listed in Appendix 1 of the Order for Enforcement of the Act on Confirmation, etc., of Release Amounts of Specific Chemical Substances in the Environment and the Promotion of Improvements to the Management Thereof (Cabinet Order No.138 of 2000). 第一種指定化学物質特定化学物質の環境への排出量の把握等及び管理の改善の促進に関する法律施行令 ( 平成 12 年政令第 138 号 ) 別表第 1 に掲げるもの h Class 2 Designated Chemical Substances as listed in Appendix 2 of the Order for Enforcement of the Act on Confirmation, etc., of Release Amounts of Specific Chemical Substances in the Environment and the Promotion of Improvements to the Management Thereof (Cabinet Order No.138 of 2000). 第二種指定化学物質特定化学物質の環境への排出量の把握等及び管理の改善の促進に関する法律施行令 ( 平成 12 年政令第 138 号 ) 別表第 2 に掲げるもの i High Pressure Gases as stipulated in Articles 2 and 3 of the High Pressure Gas Safety Act (Act No. 204 of 1951). 高圧ガス高圧ガス保安法 ( 昭和 26 年法律第 204 号 ) 第 2 条及び第 3 条に規定するもの j Volatile Organic Compounds (VOCs) as stipulated in Article 2, Paragraph 4 of the Air Pollution Control Act (Act No. 97 of 1968). 揮発性有機化合物 (VOC) 大気汚染防止法 ( 昭和 43 年法律第 97 号 ) 第 2 条第 4 項に規定するもの k Specified Offensive Odor Substances as stipulated in Article 2, Item 1 of the Offensive Odor Control Act (Act No. 91 of 1971). 特定悪臭物質悪臭防止法 ( 昭和 46 年法律第 91 号 ) 第 2 条第 1 号に規定するもの l Specified Substances, Designated Substances, Class1 Materials, and Organic Chemicals as stipulated in Articles 2 and 29 of the Act on the Prohibition of Chemical Weapons and the Regulation of Specific Chemicals (Act No. 65 of 1995). 特定物質 指定物質 第一種指定物質及び有機化学物質化学兵器の禁止及び特定物質の規制等に関する法律 ( 平成 7 年法律第 65 号 ) 第 2 条及び第 29 条に規定するもの m Agricultural Chemicals as stipulated in Article 1-2, Paragraph 1 of the Agricultural Chemicals Regulation Act (Act No. 82 of 1948). 農薬農薬取締法 ( 昭和 23 年法律 82 号 ) 第 1 条の 2 第 1 項に規定するもの n Chemical Herbicides as stipulated in Article 10-3 of the Agricultural Chemicals Regulation Act (Act No. 82 of 1948). 2 22

27 除草剤農薬取締法第 10 条の 3 に規定するもの o Explosives as stipulated in Article 2, Paragraph 1 of the Explosives Control Act (Act No. 149 of 1950). 火薬類火薬類取締法 ( 昭和 25 年法律第 149 号 ) 第 2 条第 1 項に規定するもの p Chemical substances prescribed in the Guidelines for Preventing Health Impairment by Chemical Substances issued by the Minister of Health, Labour, and Welfare based on the provision of Article 28, Paragraph 3 of the Industrial Safety and Health Act. 労働安全衛生法第 28 条第 3 項の規定に基づき厚生労働大臣が定める化学物質による健康障害を防止するための指針に規定するもの q In addition to a p above, other materials that are chemically or biologically hazardous or dangerous. a から p までに掲げるもののほか化学的 生物的な有害性 危険性を有するもの r Wastes produced by the use of any of a q above. a から q までに掲げるものの使用により生じた廃棄物 (3) New Chemical Materials means the Chemical Materials newly created by synthesis or the like. 新規化学物質 とは 合成等によって新規に作り出された化学物質のことをいう (4) Risk Assessment means a series of measures to prevent disasters from occurring, which includes assessing the types and levels of potential hazards and the toxicity of the Chemical Materials (hereinafter referred to as Hazards ) as well as the levels of health impairment likely to be caused by exposure to the Chemical Materials and reducing such risks. リスクアセスメント とは 化学物質の有害性及び危険性の種類及び程度 ( 以下 有害性等 という ) 及び化学物質のばく露により生ずるおそれがある健康障害の程度を評価し リスク低減を図ることにより 災害を未然に防ぐための一連の手法のことをいう (Relevance to Statutory Provisions and Other University Rules 法令及び諸規程との関連 ) Article 3 第 3 条 In addition to these Rules, the proper use and management of Chemical Materials are also governed by statutory provisions, administrative guidelines, and other Rules of the University. 化学物質の適正な使用及び管理については この規程に定めるほか 法令 指針及び本学の諸規程等の定めるところによる (Responsibilities of Provost プロボーストの責務 ) Article 4 第 4 条 1 The Provost shall oversee the proper use and management of Chemical Materials at the University. プロボーストは 本学の化学物質の適正な使用及び管理を総理する 2 The Provost shall appoint a Chemical Materials Safety Officer from University employees who are recognized to have sufficient knowledge and experience in 3 23

28 handling Chemical Materials. プロボーストは 化学物質の取扱いに関する知識及び経験を有すると認められる職員のうちから 化学物質安全管理者を任命する (Responsibilities of the Dean 研究科長の責務 ) Article 5 第 5 条 1 The Dean shall be responsible for implementing Risk Assessment activities and for providing appropriate safety measures to prevent graduate students from experiencing health impairments or being involved in a criminal case or an accident resulting from the use of or coming into contact with Controlled Substances. In addition, the Dean shall provide graduate students with educational guidance regarding the safe handling of Controlled Substances in cooperation with the Faculty and Research Safety Section Leader. 研究科長は 大学院生が規制物質に起因する健康障害や事件 事故を被らないようにリスクアセスメント及び必要な安全対策を執らなければならない また 教員及び研究安全セクションリーダーと連携して 大学院生に対する規制物質の安全な取扱いに係る教育的指導を行わなければならない 2 The Dean shall ensure that graduate students comply with statutory provisions and administrative guidelines pertaining to Controlled Substances and these Rules. 研究科長は 大学院生が規制物質に関係する法令及び指針並びに本規程を遵守していることを確保しなければならない (Responsibilities of the Research Safety Section Leader 研究安全セクションリーダーの責務 ) Article 6 第 6 条 As the chief officer in charge of research safety, the Research Safety Section Leader shall manage and supervise the use and management of Chemical Materials at the University. 研究安全セクションリーダーは本学における研究安全の統括責任者として 化学物質の使用及び管理について管理監督を行う (Responsibilities of the Chemical Materials Safety Officer 化学物質安全管理者の責務 ) Article 7 第 7 条 The Chemical Materials Safety Officer shall instruct, advise, and inspect the use and management of Chemical Materials and manage the OIST Chemical Management System (hereinafter referred to as CMS ) under the guidance and supervision of the Research Safety Section Leader. 化学物質安全管理者は 研究安全セクションリーダーの指揮監督の下に 化学物質の使用及び管理に関する指導 助言 点検及び OIST 化学物質管理システム ( 以下 CMS という ) の管理を行う (Responsibilities of Faculty and Section Leaders 教員及びセクションリーダーの責務 ) Article 8 第 8 条 1 Faculty and Section Leaders shall implement Risk Assessment activities and provide appropriate safety measures to prevent employees and students in his or her 4 24

29 Research Unit or Section (hereinafter referred to as Members ) from experiencing health impairments or being involved in a criminal case or an accident resulting from the use of or interaction with Controlled Substances. 教員及びセクションリーダーは 所管する研究ユニット又はセクションの職員及び学生 ( 以下 メンバー という ) が 規制物質に起因する健康障害や事件 事故を被らないようリスクアセスメント及び必要な安全対策を執らなければならない 2 The Faculty and Section Leaders shall ensure that Members comply with statutory provisions and administrative guidelines pertaining to Controlled Substances and these Rules. 教員及びセクションリーダーは メンバーが規制物質に関係する法令及び指針並びに本規程を遵守していることを確保しなければならない 3 The Faculty and Section Leaders shall ensure that all Chemical Materials under his or her management are registered in CMS and properly stored. 教員及びセクションリーダーは 所管する化学物質が CMS に登録されていること及び適正に保管されていることを確保しなければならない (Responsibilities of Users of Chemical Materials 化学物質を取扱う者の責務 ) Article 9 第 9 条 1 Any handling of Controlled Substances shall not commence unless the User familiarizes himself or herself with the chemical properties, hazard levels, toxicity, and any precautions regarding the Controlled Substances by use of a Material Safety Data Sheet or other information in advance. 規制物質を取扱う場合は 化学物質安全性データシート等により取扱う規制物質の性状 危険性 有害性 取扱い上の注意点等を事前に把握しなければならない 2 Any handling of Controlled Substances shall not commence without providing appropriate safety measures, such as wearing personal protective equipment or using a safety system, such as a fume hood. 規制物質を取扱う場合は 個人防護具の装着及びヒュームフード等の安全対策機器を用いるなど 必要な安全対策を執らなければならない 3 All Users of Chemical Materials shall comply with statutory provisions, administrative guidelines, and these Rules and shall use and manage the Chemical Materials properly and safely in accordance with the guidance and supervision of their Faculty and Section Leaders. 化学物質を取扱う者は 法令 指針及び本規程を遵守するとともに教員及びセクションリーダーの指揮監督に従い 化学物質を適正 かつ安全に使用及び管理しなければならない 4 Users of Chemical Materials shall register the Chemical Materials in CMS prior to use and shall also properly store them. 化学物質を取扱う者は 使用する化学物質を CMS に登録するとともに適正に保管しなければならない (Chemical Management System 化学物質管理システム ) Article 10 第 10 条 1 Unless otherwise specified, all Chemical Materials used and managed at OIST shall 5 25

30 be registered in CMS. OIST で使用及び管理される化学物質は 原則として CMS に登録しなければならない 2 Among the Chemical Materials, those requiring special safety or security measures, such as Poisonous Substances, Deleterious Substances, Narcotics, Psychotropics, Organic Solvents, and Specified Chemical Substances, shall be recorded for their amount of consumption through the use of CMS. Chemical Materials other than these shall be registered at the time of the purchase and disposal. Chemical Materials subject to having the amount of consumption recorded in CMS shall be prescribed in the OIST Chemical Management Guide. 化学物質のうち 毒物 劇物 麻薬 向精神薬 有機溶剤 特定化学物質等安全又は防犯対策上留意を要するものは CMS を使って使用量を記録しなければならない その他の化学物質は 購入時及び廃棄時に登録処理を行わなければならない CMS に使用量を記録する必要のある化学物質は OIST 化学物質マニュアルに定める 3 Procedures for registering Chemical Materials in CMS and the operation methods of CMS shall be prescribed in the OIST Chemical Management Guide. 化学物質の CMS への登録手順及び CMS の運用方法については OIST 化学物質取扱いマニュアルに定める (New Chemical Materials 新規化学物質 ) Article 11 第 11 条 1 Any person who intends to synthesize New Chemical Materials shall estimate the hazard level and toxicity of the New Chemical Materials aimed to be produced on the basis of the properties of the ingredients in the Chemical Materials, the possible chemical structure of the New Chemical Materials, and other information and shall implement Risk Assessment activities prior to commencing. 新規化学物質を合成しようとする者は 原材料となる化学物質の性状及び予測される化学構造等から新規化学物質の危険性及び有害性を推定し 事前にリスクアセスメントを実施しなければならない 2 The person who intends to synthesize New Chemical Materials shall report the actions implemented as a result of the Risk Assessment undertaken pursuant to the preceding Paragraph to the respective Faculty and Section Leaders. 新規化学物質を合成しようとする者は 前項のリスクアセスメントの結果を教員及びセクションリーダーに報告しなければならない 3 In the event that Faculty and Section Leaders find that the New Chemical Materials are potentially hazardous or toxic, he or she shall notify the person who intends to synthesize the New Chemical Materials and all other concerned persons of the hazard levels of the New Chemical Materials and the measures that can be taken to prevent health impairments caused by these materials and also provide measures for preventing health hazards and accidents. If the chemical properties of the New Chemical Materials cannot be inferred, then the New Chemical Materials shall be handled as though hazardous and toxic. 教員及びセクションリーダーは 当該新規化学物質が危険性又は有害性を有すると推測される場合は 新規化学物質の有害性等に関する情報及びこれらの物質による 6 26

31 健康障害防止措置に関する情報等を 新規化学物質を取り扱う者及び関係する者に通知し 健康被害及び事故を未然に防止するための措置を執らなければならない 新規化学物質の性質を推測することができない場合は 危険性又は有害性を有するものとして取り扱わなければならない 4 When transferring New Chemical Materials, the person shall notify the receiving party of information regarding the hazardousness and toxicity of the New Chemical Materials in writing. 新規化学物質を譲渡しようとする場合は 相手方に危険性及び有害性等に関する情報を文書で通知しなければならない 5 When receiving New Chemical Materials, the person shall obtain information regarding the hazardousness and toxicity of the Chemical Materials from the transferring party and shall provide and engage in appropriate safety measures on the basis of the received information. 新規化学物質を受領する場合は 相手方から当該新規化学物質の危険性及び有害性等に関する情報を入手し それに基づいて適切な措置を執らなければならない (Chemical Storage 薬品保管庫 ) Article 12 第 12 条 1 The Chemical Storage shall be a common facility and will be managed by the Research Safety Section. Any chemical cabinet to be placed in the Chemical Storage shall be purchased and placed by the Research Safety Section, in principle. 薬品保管庫は共通施設であり その管理は研究安全セクションが行う 薬品保管庫に設置する薬品キャビネットは 原則として研究安全セクションが購入及び設置する 2 The Chemical Materials can be stored in the Chemical Storage in addition to exclusive storage space owned by each unit and section. 化学物質は 各ユニット及びセクション占用スペースの他薬品保管庫に保管することができる 3 If any of the Chemical Materials are required to be stored in the Chemical Storage, the Faculty and Section Leaders shall request it to the Chemical Materials Safety Officer. The Chemical Materials Safety Officer shall assign available chemical cabinets through coordination with existing users. 薬品保管庫に化学物質の保管を希望する場合 教員及びセクションリーダーは化学物質安全管理者に申し出る 化学物質安全管理者は 既存のユーザーと調整を行い利用可能な薬品キャビネットの割り当てを行う 4 The Faculty and Section Leaders shall also be responsible for the management of the Chemical Materials stored in the Chemical Storage. 薬品保管庫に保管している場合でも 化学物質の管理責任は教員及びセクションリーダーにある (Emergency Measures 緊急時の措置 ) Article 13 第 13 条 1 A person who has discovered an incident or accident involving Controlled Substances shall immediately notify the relevant Faculty or Section Leaders, and if 7 27

32 the situation is serious or hazardous, alert all people in the surrounding area. 規制物質に関連する事件又は事故を発見した者は 直ちに その旨を関連する教員及びセクションリーダーに連絡するとともに 危険な状態である場合は 周辺にいる者にその旨を周知しなければならない 2 Faculty and Section Leaders shall undertake appropriate measures to ensure every person s safety and shall report the incident or accident to the Chemical Materials Safety Officer. 教員及びセクションリーダーは 安全確保に必要な措置を講じるととともに 化学物質安全管理者に報告しなればならない 3 Upon receipt of a report created pursuant to the preceding Paragraph, the Chemical Materials Safety Officer shall immediately identify any abnormality related to the situation and provide a description thereof to the President and Provost via the Research Safety Section Leader, and shall also provide appropriate instructions to Faculty and Section Leaders. 化学物質安全管理者は 前項の報告を受けたときは 直ちに異常事態の内容を確認し 研究安全セクションリーダーを経由して学長及びプロボーストに報告するとともに教員及びセクションリーダーに対し必要な指示をしなければならない 4 The Chemical Materials Safety Officer shall keep records of the description of all incidents and accidents as well as post-incident and accident measures. 化学物質安全管理者は 事件及び事故の内容 事後措置等について記録をとるものとする 5 In case of serious incidents or accidents, the President shall promptly notify the Police, Governor of Okinawa Prefecture, or other competent Minister of the incident or accident and provide a description of the incident or accident and a summary of the measures subsequently undertaken. 学長は 重大な事件又は事故の場合は 速やかにその事故の状況及び執った措置の概要を 警察 沖縄県知事又は関係大臣に届け出るものとする (Disposal 廃棄 ) Article 14 第 14 条 Procedures necessary for the disposal of Chemical Materials are prescribed in the Rules for the Management of Waste. 化学物質の廃棄に関し必要な事項は 廃棄物管理規程に定める (Training Programs 教育訓練 ) Article 15 第 15 条 All Users of Chemical Materials shall participate in training programs regarding relevant statutory provisions, administrative guidelines and OIST Rules, procedures regarding Chemical Materials, and the proper use, storage, and disposal of Chemical Materials prior to working with them. 化学物質を取扱う者は 事前に 関係する法令 指針及び OIST の諸規程 化学物質に係る手続き並びに化学物質の適切な使用 保管及び廃棄についての教育訓練を受講しなければならない (Responding to Neighboring Residents 近隣住民等への対応 ) 8 28

33 Article 16 第 16 条 1 The Provost shall take any and all appropriate steps to obtain the understanding of neighboring residents and municipalities about the management of Controlled Substances. プロボーストは 規制物質の管理について 近隣住民及び周辺地域の理解を得るための必要な措置を講じなければならない 2 Users of Controlled Substances and the Chemical Materials Safety Officer shall provide neighboring residents and municipalities with appropriate information as needed in order to obtain their understanding and shall respond sincerely to any opinions or complaints regarding the management of Controlled Substances. 規制物質を取扱う者及び化学物質安全管理者は 近隣住民及び周辺地域の理解を得るため 必要な情報の提供を行うとともに 規制物質の管理に関する意見及び苦情等に誠実に対処しなければならない (Auxiliary Provisions 補則 ) Article 17 第 17 条 In addition to the matters stipulated in these Rules, separate provisions shall apply to the matters regarding Poisonous and Deleterious Substances, Narcotics and Psychotropics, Nuclear Fuel Materials, and Nuclear Source Materials and Radioisotopes. この規程に定めるもののほか 毒物及び劇物 麻薬及び向精神薬 核燃料物質及び核原料物質 放射性同位元素に関し必要な事項は別に定める Supplementary Provisions Record of Controlled Substances shall be made using a ledger sheet or computer until when CMS is introduced. 附則 化学物質管理システムが導入されるまでは 帳簿又はコンピュータを利用して規制物質の記録をとるものとする Supplementary Provisions (Rules Version 1.00, February 28, 2013) 附則 ( 平成 25 年 2 月 28 日第 1.00 版 ) These Rules shall come into effect beginning February 28, この規程は 平成 25 年 2 月 28 日から施行する 9 29

34 OIST Graduate University Rules for Poisonous and Deleterious Substances Management 沖縄科学技術大学院大学毒物及び劇物管理規程 (Version 1.00, February 28, 2013) ( 平成 25 年 2 月 28 日第 1.00 版 ) (Purpose 目的 ) Article 1 第 1 条 These Rules set forth the handling and management of poisonous and deleterious substances (hereinafter referred to as Substances ) at the OIST Graduate University (hereinafter referred to as University ). この規程は 沖縄科学技術大学院大学 ( 以下 本学 という ) における毒物及び劇物 ( 以下 毒劇物 という ) の取扱い及び管理に関する事項を定める (Definitions of Terms 用語の定義 ) Article 2 第 2 条 As used in these Rules, in addition to the definitions provided in the Poisonous and Deleterious Substances Control Act (Act No. 303 of 1950, hereinafter referred to as Act ), these definitions apply: この規程において用いる用語の定義は 毒物及び劇物取締法 ( 昭和 25 年法律第 303 号 以下 毒劇法 という ) の定めるところによる他 次の各号に定めるところによる (1) Poisonous Substances means any poisonous substance as defined in Paragraph 1, Article 2 of the Act. 毒物毒劇法第 2 条第 1 項に定めるものをいう (2) Deleterious Substances means any deleterious substance as defined in Paragraph 2, Article 2 of the Act. 劇物毒劇法第 2 条第 2 項に定めるものをいう (3) Specified Poisons means any of the specified poisons as defined in Paragraph 3, Article 2 of the Act. 特定毒物毒劇法第 2 条第 3 項に定めるものをいう (4) Acquisition means to receive any Substances from any other party (including another research unit or section belonging to the University) by transfer, with the exception of purchase. 譲受け毒劇物を他の者 ( 本学に所属する他の研究ユニット又はセクションを含む ) から譲り受けること ただし 購入を除く (5) Transfer means to transfer any Substances owned by a research unit or a section to any other party (including another research unit or section belonging to the University). 譲渡し研究ユニット又はセクションが所有している毒劇物を他の者 ( 本学に所属する他の研究ユニット又はセクションを含む ) へ譲り渡すことをいう (6) Chemical Materials Safety Officer means the person defined in Article 7 of 1 30

35 the OIST Graduate University Rules for the Management of Chemical Materials. 化学物質安全管理者沖縄科学技術大学院大学化学物質管理規程第 7 条に定める者をいう (7) Substances Assistant means the person who assists the Faculty or Section Leader to manage the Substances in each research unit or section. 毒劇物管理担当者各研究ユニット又はセクションにおいて 教員又はセクションリーダーの毒劇物管理業務を補佐する者をいう (Relevance to Statutory Provisions and Other University Rules 関連法令及び諸規程との関連 ) Article 3 第 3 条 The handling and management of any Substances are also governed by the Act; the library of OIST Graduate University Policies, Rules, and Procedures; and the OIST Rules for the Management of Chemical Materials, in addition to the Rules set forth herein. 毒劇物の取扱い及び管理については この規程に定める他 毒劇法 沖縄科学技術大学院大学基本方針 ルール 手続きライブラリ及び沖縄科学技術大学院大学化学物質管理規程の定めるところによる (Responsibilities of Faculty and Section Leaders 教員及びセクションリーダーの責務 ) Article 4 第 4 条 1 Faculty and Section Leaders shall be responsible for the application, procurement, storage, handling, and disposal of Substances. 教員及びセクションリーダーは 所管する研究ユニット又はセクションにおいて 毒劇物に係る申請 購入 保管 取扱い及び廃棄について責任を有する 2 Faculty and Section Leaders may appoint, where necessary, a Substances Assistant from among the members of each unit or section. 教員及びセクションリーダーは 所管する研究ユニット又はセクションに所属する者の中から必要に応じて毒劇物管理担当者を指名する 3 After appointing the Substances Assistant or changing the person appointed, the Faculty and Section Leaders shall submit a Report on Appointment or Change of Substances Assistant (Form 1) to the Provost via the Chemical Materials Safety Officer. 教員及びセクションリーダーは 前項の毒劇物管理担当者を指名したとき又はこれを変更したときは 毒劇物管理担当者指名 変更届 ( 様式 1) を化学物質安全管理者に提出しなければならない (Application for Specified Poisons Researcher 特定毒物研究者の申請 ) Article 5 第 5 条 1 A person who intends to produce or use Specified Poisons shall seek approval from the Provost via the Chemical Materials Officer by submitting an Application for Specified Poisons Researcher (Form 2). 特定毒物を製造又は使用しようとする者は 特定毒物研究者申請 ( 様式 2) を化学物質安全管理者を経由してプロボーストに提出し その承認を求める 2 31

36 2 When recognizing a safety problem in the use as stated in the application produced pursuant to the preceding Paragraph, the Chemical Materials Safety Officer and Research Safety Section Leader shall provide instructions, advice, or recommendations to the applicant. 化学物質安全管理者及び研究安全セクションリーダーは 前項の申請について安全上問題があると判断したときは 必要な指示又は勧告をしなければならない 3 Upon receipt of approval by the Provost for the application pursuant to Paragraph 1, the applicant shall submit an Application for Permission of Specified Poisons Researcher based on Article 6-2 of the Act to the Governor of the Okinawa Prefecture in accordance with the instructions of the Chemical Materials Officer. 第 1 項に規定するプロボーストの承認後 申請者は化学物質安全管理者の指示に従って 毒劇法第 6 条の 2 の規定に基づき特定毒物研究者許可申請書を沖縄県知事に提出しなければならない 4 The person who has received a Permit for Specified Poisons Researcher shall take a photocopy thereof and promptly submit the photocopy to the Chemical Materials Officer. 特定毒物研究者許可証を受領した者は 速やかにその写しを化学物質安全管理者に提出しなければならない 5 In the event that there is a change in any matters described in the Permit as defined in Paragraph 2, Article 10 of the Act, the provisions of Paragraphs 1 4 apply mutatis mutandis. 毒劇法第 10 条第 2 項の規定する許可書の内容に変更が生じた場合 第 1 項から第 4 項までの規定を準用する (Limitation to Receipt 入手の制限 ) Article 6 第 6 条 Acquisition and purchase of Substances for any purpose other than University business purposes is prohibited. 本学の業務の目的外で 毒劇物を譲受け及び購入してはならない (Acquisition 譲受け ) Article 7 第 7 条 Following the acquisition of Substances, the person shall notify the Chemical Materials Safety Officer by submitting the Report on Acquisition of Substances (Form 3). 毒劇物を譲り受けた場合は 毒劇物譲受け届 ( 様式 3) を化学物質安全管理者に提出しなければならない (Transfer 譲渡し ) Article 8 第 8 条 1 Transfer of Substances to other parties outside the University is prohibited unless approved by the Chemical Materials Safety Officer. 化学物質安全管理者が特に認める場合を除き 毒劇物の本学外の者への譲渡しを行ってはならない 2 When Substances are transferred to another Unit or section in the University, the 3 32

37 person shall notify the Chemical Materials Safety Officer by submitting the Report on Transfer of Substances (Form 4). 毒劇物を本学内の他の研究ユニット又はセクションに譲り渡す場合 毒劇物譲渡し届 ( 様式 4) を化学物質安全管理者に提出しなければならない (Standards for Storing Substances and Labeling 毒劇物の保管上の基準と表示 ) Article 9 第 9 条 1 Substances shall be stored in a locked strong cabinet dedicated to chemical materials (hereinafter referred to as the Cabinet ). The Cabinet shall be locked at all times when the chemical materials are not in use. 毒劇物は 薬品専用の鍵付で強固な保管庫 ( 以下 保管庫 という ) に保管し 保管中は施錠しておかなければならない 2 The Cabinet key shall be kept and managed by the Faculty, Section Leaders, or Substances Assistants. 保管庫の鍵は 教員 セクションリーダー又は毒劇物管理担当者が管理する 3 Substances and other chemicals shall be stored separately. 毒劇物又は他の薬品類は 区分して保管する 4 The Faculty, Section Leaders, and Substances Assistants shall take appropriate measures so that Substances will not leak or be released during storage. 教員 セクションリーダー及び毒劇物管理担当者は 保管中に毒劇物が漏えい又は流出しないような措置を講じなければならない 5 When Substances are produced or repackaged, they must be stored in laboratory containers and not in containers otherwise used for food or drink. 毒劇物を製造し 又は小分けする場合は 飲食物用以外の専用の容器に保存しなければならない 6 The Faculty, Section Leaders, and Substances Assistants shall attach proper labels, as indicated below, on the Cabinet and containers on the basis of Article 12 of the Act. 教員 セクションリーダー及び毒劇物管理担当者は 毒劇物が入っている保管庫及び保管容器に 毒劇法第 12 条に基づき 当該各号に定める表示をしなければならない (1) Common indication for both Poisonous and Deleterious Substances: 医薬用外 (Not intended for medicinal use) 毒物及び劇物共通 : 医薬用外 (2) Poisonous Substances: 毒物 (Poisonous Substance) with a red base and white letters 毒物 : 赤地に白色で 毒物 (3) Deleterious Substances: 劇物 (Deleterious Substance) with a white base and red letters 劇物 : 白地に赤色で 劇物 (Standards for Handling 取扱上の基準 ) Article 10 第 10 条 1 When taking Substances out of the Cabinet, the person who handles the Substances (hereinafter referred to as the User ) shall keep the Substances within a range in 4 33

38 which the User can see them while working. Otherwise, he or she shall keep them in a locked Cabinet. 毒劇物を取扱う者 ( 以下 取扱者 という ) は 毒劇物を保管庫から持ち出したときには 必ず当該毒劇物に目の届く範囲で作業を行わなければならない これができない場合は 保管庫にて保管し 施錠しておかなければならない 2 The User shall fully familiarize himself or herself with the chemical properties of the Substances before working with them. 取扱者は 事前に取り扱う毒劇物の性状等について十分に把握していなければならない 3 The User shall wear appropriate personal protective equipment and use a local exhaust ventilation system as needed. 取扱者は 必要に応じて保護具を着用し 局所排気設備を使用するものとする 4 The User shall take appropriate measures so that the Substances will not leak or be released while working with them. 取扱者は 取り扱う毒劇物が漏えい又は流出しないような措置を講じなければならない (Log for Substances 毒劇物の使用記録 ) Article 11 第 11 条 1 The amount of each use of the Substances shall be recorded using the OIST Chemical Management System. 毒劇物は OIST 化学物質管理システムを用いて 使用量を記録しなければならない 2 The Faculty, Section Leaders, and Substances Assistants shall be responsible for managing the logs, as defined in the preceding Paragraph. 教員 セクションリーダー及び毒劇物管理担当者は 前項に規定する毒劇物の使用量の記録を管理する 3 When the OIST Chemical Management System is not accessible, the log for the amount of each use of the Substances shall be recorded in a logbook. OIST 化学物質管理システムが利用できない場合は 帳簿によって毒劇物の使用量を記録しなければならない 4 When a log is recorded in a logbook, as noted in the preceding Paragraph, the quantity of the Substances stored as of the end of March and the end of September of each year as well as the amount of consumption of the Substances during the preceding six months shall be reported to the Chemical Materials Safety Officer no later than the 15th of the next month. 前項の帳簿によって使用記録を行っている場合は 毎年 3 月末及び 9 月末時点における毒劇物の保管量及び半年間の使用量を 当該月の翌月 15 日までに 化学物質安全管理者に報告しなければならない (At the End of Use 取扱い終了時 ) Article 12 第 12 条 1 When the Faculty and Section Leaders are about to finish his or her handling of the Substances by reason of his or her retirement, he or she may transfer the Substances managed by him or her to other units or sections in the University. 5 34

39 教員及びセクションリーダーは退職等により毒劇物の取扱いを終了する場合 毒劇物を本学の他の研究ユニット又はセクションに譲り渡すことができる 2 In the event that the Faculty or Section Leaders are unable to make such a transfer of Substances, he or she is obliged to dispose of the Substances. 管理している毒劇物の譲渡し先を選定できない場合 教員又はセクションリーダーは毒劇物を廃棄する (Emergency Measures 緊急時の措置 ) Article 13 第 13 条 1 In the event of theft or the loss of Substances, the person shall immediately notify the relevant faculty or Section Leader of the incident. 毒劇物が盗難に遭い 又は紛失したときは 直ちに教員又はセクションリーダーに届け出なければならない 2 In the cases prescribed in the preceding Paragraph, the Faculty and Section Leader shall immediately report the incident to the President and Provost via the Chemical Materials Safety Officer and Research Safety Section Leader. 前項の場合において 教員及びセクションリーダーは 直ちに化学物質安全管理者及び研究安全セクションリーダーを経由して学長及びプロボーストに報告しなければならない 3 Upon receipt of the report pursuant to the preceding Paragraph, the President shall take appropriate measures, such as notifying the Police. 前項の報告を受けた学長は 警察に届け出る等の必要な措置を講じなければならない (Training Programs 教育及び訓練 ) Article 14 第 14 条 All Users of the Substances shall participate in training programs regarding the Substances prior to working with them. 取扱者は 事前に毒劇物に関する教育及び訓練を受講しなければならない (Auxiliary Provisions 補則 ) Article 15 第 15 条 In addition to the matters stipulated in these Rules, other matters necessary for the handling and managing of Substances may be provided separately. この規程に定めるもののほか 毒劇物の取扱い及び管理に関し必要な事項は別に定める Supplementary Provisions (Rules Version 1.00, February 28, 2013) 附則 ( 平成 25 年 2 月 28 日第 1.00 版 ) These Rules shall come into effect from February 28, この規程は 平成 25 年 2 月 28 日から施行する 6 35

40 Report on Appointment or Change of Substances Assistant Chemical Materials Safety Officer, Signature/Seal Section Leader, Research Safety, Signature/Seal Date: Month Date, Year To: Chemical Materials Safety Officer From: Faculty or Section Leader Name Signature/Seal Name of Research Unit or Section: I have appointed the person below as a Substances Assistant in accordance with the provisions of Paragraph 3, Article 4 of the OIST Graduate University Rules for Poisonous and Deleterious Substances Management. Unit/Section: Title: Name (Print): Signature: Name of predecessor in the event of change: 36 Form No. 1 (related to Article 4)

41 Application for Specified Poisons Researcher Chemical Materials Safety Officer, Signature/Seal Section Leader, Research Safety, Signature/Seal Date: Month Date, Year To: Provost From: Applicant of Permission for Specified Poisons Researcher Name Signature/Seal Name of Research Unit or Section: Faculty or Section Leader Name Signature/Seal I file for permission to act as a Specified Poisons Researcher to the Governor of the Okinawa Prefecture, in accordance with the provisions of Paragraph 1, Article 5 of the OIST Graduate University Rules for Poisonous and Deleterious Substances Management: 1. Project title of requiring use of poisons: 2. Specified poisons to be used: 37 Form No. 2 (related to Article 5)

42 Report on Acquisition of Substances Chemical Materials Safety Officer, Signature/Seal Section Leader, Research Safety, Signature/Seal Date: Month Date, Year To: Chemical Materials Safety Officer From: Name Signature/Seal Name of Research Unit or Section: Faculty or Section Leader Name Signature/Seal This is to report the acquisition of Substances as below, in accordance with the provisions of Article 7 of the OIST Graduate University Rules for Poisonous and Deleterious Substances Management: 1. Poisonous Substances Deleterious Substances Specified Poisons 2. Name of Substances: 3. Amount: 4. Date of Acquisition: 5. Provider (1) Name: (2) Institution/Organization and Department (3) Contact Information Address: Phone Number: 38 Form No. 3 (related to Article 7)

43 Report on Transfer of Substances Chemical Materials Safety Officer, Signature/Seal Section Leader, Research Safety, Signature/Seal Date: Month Date, Year To: Chemical Materials Safety Officer From: Name Signature/Seal Name of Research Unit or Section: Faculty or Section Leader Name Signature/Seal This is to report a transfer of Substances as given below, in accordance with the provisions of Paragraph 2, Article 8 of the OIST Graduate University Rules for Poisonous and Deleterious Substances Management: 1. Poisonous Substances Deleterious Substances Specified Poisons 2. Name of Substances: 3. Amount: 4. Date of Acquisition: 5. Recipient: (1) Name: (2) Institution/Organization and Department (3) Contact Information Address: Phone Number: 39 Form No. 4 (related to Article 8)