Calculation of Power, Shear and Gas-liquid mass transfer in reactors for fermentation.

Similar documents
1. Starting of a project and entering of basic initial data.

VISIMIX LAMINAR. MODELING OF A STAGNANT ZONE FORMATION AS A RESULT OF INEFFICIENT MIXING.

VISIMIX TURBULENT. BATCH REACTOR SCALING UP.

PHEN 612 SPRING 2008 WEEK 12 LAURENT SIMON

VISIMIX TURBULENT. TACKLING SAFETY PROBLEMS OF STIRRED REACTORS AT THE DESIGN STAGE.

Review of the Main Mathematical Models Used in VisiMix

Flow Generated by Fractal Impeller in Stirred Tank: CFD Simulations

ENGG 199 Reacting Flows Spring Lecture 4 Gas-Liquid Mixing Reactor Selection Agitator Design

ENGG 199 Reacting Flows Spring Lecture 2b Blending of Viscous, Non-Newtonian Fluids

mixing of fluids MIXING AND AGITATION OF FLUIDS

MASS TRANSFER COEFFICIENTS DURING AERATION BY A SELF-ASPIRATING IMPELLER

An Overview of Impellers, Velocity Profile and Reactor Design

AIRLIFT BIOREACTORS. contents

Assessing Mixing Sensitivities for Scale-up. Matthew Jörgensen Atlanta, 10/20/2014

AGITATION AND AERATION

Application of the CFD method for modelling of floating particles suspension

AN OVERVIEW OF IMPELLERS, VELOCITY PROFILES AND REACTOR DESIGN

M Manuela R da Fonseca, DEQB. Mixing

Liquid Mixing in Agitated Vessels

Numerical Simulation of Flow Field in a Elliptic Bottom Stirred Tank with Bottom Baffles

Calculation of Power and Flow Capacity of Rotor / Stator Devices in VisiMix RSD Program.

CFD SIMULATION OF SOLID-LIQUID STIRRED TANKS

Nirma University Institute of Technology Chemical Engineering Department, Handouts -RRP- CRE-II. Handouts

ASSESSMENT OF THE MINIMUM POWER REQUIREMENTS FOR COMPLETE SUSPENSION IN TOP-COVERED UNBAFFLED STIRRED TANKS

Separationsteknik / Separation technology

CFD Analysis and Experimental Evaluation of the Effective Parameters on Paint Homogeneity in Mixing Tanks

Power requirements for yield stress fluids in a vessel with forward-reverse rotating impeller

PIV STUDY OF MIXING CHARACTERISTICS IN A STIRRED VESSEL WITH A NON-NEWTONIAN FLUID

NUMERICAL STUDY OF THE EFFECT OF BLADE SZE ON PUMPING EFFECTIVENESS OF A PADDLE IMPELLER IN AN UNBAFFLED MIXING VESSEL

Effect of Suspension Properties on the Electrochemical Method. Ing. Kamila Píchová

CFD ANALYSIS OF TURBULENCE EFFECT ON REACTION IN STIRRED TANK REACTORS

Verification Examples. The Comparison between Published Experimental Data and Results of VisiMix Calculations

Dense Solid-Liquid Suspensions in Top-Covered Unbaffled Stirred Vessels

PLO MIXING AND RTD IN TANKS: RADIOTRACER EXPERIMENTS AND CFD SIMULATIONS

Getting started with BatchReactor Example : Simulation of the Chlorotoluene chlorination

AGITATION/GAS-LIQUID DISPERSION. CHEM-E Fluid Flow in Process Units

PARTICLE SUSPENSION WITH A TX445 IMPELLER

PIV Study of the Turbulent Flow in a Stirred Vessel Equipped by an Eight Concave Blades Turbine

MASS TRANSFER EFFICIENCY IN SX MIXERS

MRI Flocculation. MRI Flocculation Systems. Mix & Match for Maximum Pretreatment Control

CFD Analysis of a Stirred Vessel Bioreactor with Double Pitch Blade and Rushton Type Impellers

AN INVESTIGATION INTO DIFFERENT POWER CONSUMPTION PARAMETERS OF RUSHTON TURBINES: A COMPUTATIONAL SURVEY

Oxygen transfer, mixing time and gas holdup characterization in a hybrid bioreactor

THE VELOCITY FIELD IN THE DISCHARGE STREAM FROM A RUSHTON TURBINE IMPELLER

Table of Contents. Preface... xiii

PIV Measurements to Study the Effect of the Reynolds Number on the Hydrodynamic Structure in a Baffled. Vessel Stirred by a Rushton Turbine

Modeling of turbulence in stirred vessels using large eddy simulation

Comparison of Agitators Performance for Particle Suspension in Top-Covered Unbaffled Vessels

CHEMICAL REACTION ENGINEERING LAB

Effect of the Tank Design on the Flow Pattern Generated with a Pitched Blade Turbine

EFFECT OF IMPELLER TYPE AND NUMBER AND LIQUID LEVEL ON TURBULENT BLEND TIME

Effect of the Type of Impellers on Mixing in an Electrochemical Reactor

Pharmaceutical Technologies and Process Engineering

Turbulence control in a mixing tank with PIV

THINK FLUID DYNAMIX Mixing, Homogenization & Blend Time. THINK Fluid Dynamix

Dynamic Effect of Discharge Flow of a Rushton Turbine Impeller on a Radial Baffle J. Kratěna, I. Fořt, O. Brůha

Effect of Baffles Geometry on Hydrodynamics in a Mechanically Agitated System

RELATION BETWEEN PARTICLE RISING BEHAVIOR AND LIQUID FLOW AROUND THE BOTTOM OF A STIRRED VESSEL

EVALUATION OF THE EFFECT OF PITCHED BLADE TURBINE ON MIXING IN AN ELECTROCHEMICAL REACTOR WITH ROTATING RING ELECTRODES.

EffectofBaffleDesignontheOff-bottomSuspensionCharacteristics ofaxial-flowimpellersinapilot-scalemixingvessel

THE DETAILS OF THE TURBULENT FLOW FIELD IN THE VICINITY OF A RUSHTON TURBINE

RADIOTRACER RESIDENCE TIME DISTRIBUTION METHOD IN DIAGNOSING INDUSTRIAL PROCESSING UNITS: CASE STUDIES

Modeling Industrial Crystallizers

Simulation of Multiphase Flow in Stirred Tank of Nonstandard Design

Study on residence time distribution of CSTR using CFD

RHEOLOGY AND MIXING OF SUSPENSION AND PASTES. Pr Ange NZIHOU, EMAC France

Numerical Comparison of Rushton Turbine and CD-6 Impeller in Non-Newtonian Fluid Stirred Tank Akhilesh Khapre, Basudeb Munshi

An Essential Requirement in CV Based Industrial Appliances.

THE FUTURE OF THE CHEMISTRY: CONTINUOUS FLOW REACTIONS BASEL 2016

Comparison of Different Techniques for Modelling of Flow Field and Homogenization in Stirred Vessels*

Chemical Reaction Engineering

Fundamental Concepts of Convection : Flow and Thermal Considerations. Chapter Six and Appendix D Sections 6.1 through 6.8 and D.1 through D.

Fluid Dynamic Simulations of Wind Turbines. John Abraham, Brian Plourde, Greg Mowry University of St. Thomas

In this lecture... Radial flow turbines Types of radial flow turbines Thermodynamics and aerodynamics Losses in radial flow turbines

ENGINEERING FLUID MECHANICS. CHAPTER 1 Properties of Fluids

Experimental identification of the flow vortex structures generated in the agitated vessels

UNIVERSITA DEGLI STUDI DI PISA. Facoltà di Ingegneria Corso di Laurea in Ingegneria Chimica. Tesi di Laurea

Emulsification in Batch-Emulsion Polymerization of Styrene and Vinyl Acetate: AReaction Calorimetric Study

Scale-up Design of A Multiple Impeller Gas-Liquid Contactors

APPLICATION OF MODELS WITH DIFFERENT COMPLEXITY FOR A STIRRED TANK REACTOR

Treatment Processes. Coagulation. Coagulation. Coagulation. Coagulation. Coagulation and Flocculation

Estimation of Agitator Flow Shear Rate

APPLICATION OF STIRRED TANK REACTOR EQUIPPED WITH DRAFT TUBE TO SUSPENSION POLYMERIZATION OF STYRENE

Scale Up of Liquid and Semisolid Manufacturing Processes

MIXING 97 Multiphase Systems

Ivan FORT and lana MALA

Mixing time of surface active agent solutions

by Wensheng Zhang, Fuping Hao, Yoko Pranolo, Chu Yong Cheng, and Dave Robinson Presented by Wensheng Zhang 8 July 2011

VisiMix Conference. October 20-22, Victor A. Atiemo-Obeng, PhD, FAIChE. Retiree from The Dow Chemical Company

PIV MEASUREMENTS AND CFD SIMULATION OF VISCOUS FLUID FLOW IN A STIRRED TANK AGITATED BY A RUSHTON TURBINE

3D hot-wire measurements of a wind turbine wake

THE COMPUTATIONAL-FLUID-DYNAMICS STUDY OF AN UNBAFFLED STIRRED VESSEL WITH ECCENTRICALLY POSITIONED IMPELLER

1 Turbidity = NTU 2 ph = Alkalinity = 34 mg/l as CaCO 3 4 Temperature = 5 Fe = 2 mg/l 6 Mn = mg/l 7 Total Hardness = 50mg/l as CaCO 3

ARTICLE IN PRESS. chemical engineering research and design x x x ( ) xxx xxx. Contents lists available at ScienceDirect

Computer Life (CPL) ISSN: The Numerical Simulation on Internal Gas-liquid Two Phase Flow Field of. Three Layers of Air Stirred Reactor

Flerfasforskning vid Kemisk reaktionsteknik Chalmers. Bengt Andersson Love Håkansson Ronnie Andersson

L-17 Coagulation and Flocculation Part-I. Environmental Engineering-I

CFD Modelling of the Fluid Flow Characteristics in an External-Loop Air-Lift Reactor

International Journal of Advance Engineering and Research Development. Bi-directional mixer

Continuous Flow Reactions. From idea to production size scale up in 3 steps

Transcription:

VISIMIX TURBULENT. GAS-LIQUID MIXING. FERMENTATION. Calculation of Power, Shear and Gas-liquid mass transfer in reactors for fermentation. 1. Subject of calculations and initial data. This example demonstrates application of the program VisiMix Turbulent for comparison of Oxygen dissolution rate and maximum shear stress in fermentation reactors with identical air injection parameters and with two different mixing devices 2-stage pitch paddle and 2-stage disc (Rushton) turbine. Subjects of mathematical modeling Hydrodynamics, Turbulence and Gas dispersion and mass transfer. Calculated parameters: Mixing power; Oxygen mass transfer rate; Maximum local shear stress; Relative residence time of suspension in zones of the maximum shear stress. Description of equipment. Design characteristics and main dimensions of the equipment are presented below in a form of VisiMix input tables. These tables are presented by the program automatically and must be filled before the start of modeling. Tank: Jacketed tank with elliptical bottom. The main dimensions are shown in Figure 1. Baffles: 4 flat radial baffles. The main dimensions are shown in Figure 2. Mixing devices: Project PADDLE : 2-stage Pitch paddle. Project TURBINE: 2 stage disc turbine. The main dimensions of impellers, rotation velocity and power of drives are shown in Figures 3a and 3b. Schemes of the reactors corresponding to the two projects are presented in the Figure 4. Figure 1. Input table of Tank design and main dimensions. VisiMix Turbulent. Example 6. 1

Figure 2.Input table of flat baffles position and main dimensions. Figure 3a. Characteristics of the Pitch paddle (Project name PADDLE). VisiMix Turbulent. Example 6. 2

Figure 3b. Characteristics of the Disc turbine (Project name - TURBINE). Figure 4. Schemes of reactor with two different mixing devices. The last input necessary in order to start VisiMix modeling average properties of media (see Figure 5). VisiMix Turbulent. Example 6. 3

Figure 5. Input table of Average properties of media. 2. Defining of mixing power and shear characteristics.. The first stage of mathematical modeling Hydrodynamics- is performed by selecting one of the options of HYDRODYNAMICS sub-menu (Figure 6). The calculated values of the selected parameters or functions are displayed as tables or graphs. In this example we select the parameter Mixing power (see Figure 6), and the program returns the calculated value. Output tables of Mixing power for the both projects are shown in the Figure 7. Defining of the shear stresses in turbulent flow is based on mathematical modeling of micro-scale turbulence. In this example we are interested in evaluation and comparison of shear stresses, and in particular of the maximum local shear stress values in the two reactors. Locations of the maximum values of shear stress correspond to zones of the maximum local turbulent dissipation rate in vicinity of the impeller blades. So, in the sub-menu TURBULENCE (Figure 8) we select parameters TURBULENT SHEAR RATES IN DIFFERENT ZONES, Turbulent shear stress near the impeller blade and RESIDENCE TIME IN ZONES WITH DIFFERENT TURBULENCE. The corresponding VisiMix outputs for the compared projects are presented in the Figures 9, 10 and 11. VisiMix Turbulent. Example 6. 4

Figure 6. Menu HYDRODYNAMICS. Figure 7. Output tables of Mixing power. Figure 8. Menu TURBULENCE. VisiMix Turbulent. Example 6. 5

Figure 9. Output tables of Turbulent shear rates in different zones. Figure 10. Output tables for Maximum shear stress. Figure 11. Output tables for RESIDENCE TIME IN ZONES WITH DIFFERENT TURBULENCE. 3. Evaluation of the Oxygen consumption rate. The last stage of modeling comparison of Oxygen mass transfer rates. In our example it is based on approximately assumed initial data. VisiMix Turbulent. Example 6. 6

Figure 12. Menu of Gas-Liquid mixing and mass transfer. In order to perform modeling, we must select one of the options in sub-menu GAS DISPERSION AND MASS TRANSFER.. Let us select Gas mass transfer rate (Figure 11). As a response to this action, the program will display a few input tables for entering additional data that are necessary for mass transfer calculations the data on air injection and physical properties of phases (Figures13-16). Figure 13. Data on air injection. Figure 14. Input table of Surface tension. VisiMix Turbulent. Example 6. 7

Figure 15. Input table of Oxygen diffusivity. Figure 16. Input table of Oxygen solubility. After the last of the tables is filled, the output table for the corresponding project is displayed by the program. Comparison of the mass transfer rates in the two reactors with different mixing devices is shown in the Figure 17. Figure 17. Calculated values of Oxygen consumption rate. VisiMix Turbulent. Example 6. 8