An Approach to Constructing Good Two-level Orthogonal Factorial Designs with Large Run Sizes

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An Approach to Constructing Good Two-level Orthogonal Factorial Designs with Large Run Sizes by Chenlu Shi B.Sc. (Hons.), St. Francis Xavier University, 013 Project Submitted in Partial Fulfillment of the Requirements for the Degree of Master of Science in the Department of Statistics and Actuarial Science Faculty of Science c Chenlu Shi 015 SIMON FRASER UNIVERSITY Summer 015 All rights reserved. However, in accordance with the Copyright Act of Canada, this work may be reproduced without authorization under the conditions for Fair Dealing. Therefore, limited reproduction of this work for the purposes of private study, research, criticism, review and news reporting is likely to be in accordance with the law, particularly if cited appropriately.

Approval Name: Degree: Title: Examining Committee: Chenlu Shi Master of Science (Statistics) An Approach to Constructing Good Two-level Orthogonal Factorial Designs with Large Run Sizes Dr. Tim Swartz (chair) Professor Dr. Boxin Tang Senior Supervisor Professor Dr. Richard Lockhart Supervisor Professor Dr. Liangliang Wang Internal Examiner Assistant Professor Date Defended: 0 July 015 ii

Abstract Due to the increasing demand for two-level fractional factorials in areas of science and technology, it is highly desirable to have a simple and convenient method available for constructing optimal factorials. Minimum G -aberration is a popular criterion to use for selecting optimal designs. However, direct application of this criterion is challenging for large designs. In this project, we propose an approach to constructing a good factorial with a large run size using two small minimum G -aberration designs. Theoretical results are derived that allow the word length pattern of the large design to be obtained from those of the two small designs. Regular 64-run factorials are used to evaluate this approach. The designs from our approach are very close to the corresponding minimum aberration designs, and they are even equivalent to the corresponding minimum aberration designs, when the number of factors is large. Keywords: Fractional factorial; Minimum aberration; Minimum G -aberration; Word length pattern. iii

Dedication To my family! iv

Acknowledgements I would like to express my deepest gratitude to my senior supervisor Dr. Boxin Tang for his professional guidance, unlimited patience, and great mentoring throughout my graduate studies. Without his encouragement and his insightful suggestions, this project would not have been possible. It has been such a privilege for me to be his student. I would also like to thank the members of the examining committee, Dr. Richard Lockhart and Dr. Liangliang Wang, for their thorough reading of this project and valuable feedbacks. I am grateful to all professors who taught me during the period of my graduate studies, including Dr. Jiguo Cao, Dr. Joan Hu, Dr. Brad McNeney and many others. I wish to thank Sadika, Kelly and Charlene for their kind help in the past two years. Many thanks to the Department of Statistics and Actuarial Science at Simon Fraser University for offering such a fabulous graduate program. Last but not least, I would like to thank my family, especially my parents for their unconditional love and support. v

Table of Contents Approval Abstract Dedication Acknowledgements Table of Contents List of Tables List of Figures ii iii iv v vi vii viii 1 Introduction 1 1.1 Notation and Background............................... General Theoretical Results 5.1 Constructing A Large Design Using Two Small Designs.............. 5. Doubling........................................ 6.3 Small Design Without A Column of 1 s....................... 8.4 Small Design with A Column of 1 s......................... 13 3 Applications 17 3.1 Generals......................................... 17 3. Regular 64-Run Designs with 7 m 63 Factors.................. 18 3.3 Comparison with Minimum Aberration Designs................... 0 4 Concluding Remarks 5 Bibliography 5 vi

List of Tables Table 3.1 All possible D 1 s and D s for designs 4 18................. 18 Table 3. (A 3, A 4, A 5 ) s of the best designs from our approach with 7 m 63 factors 19 Table 3.3 (A 3, A 4, A 5 ) s of minimum aberration (MA) designs and those of the corresponding best designs from our approach for 7 m 3.......... 0 Table 3.4 (A 3, A 4, A 5 ) of design D and that of the corresponding MA design D... 3 Table 3.5 (A 3, A 4, A 5 ) s of MA designs and those of the corresponding best designs from our approach for 33 m 63...................... 4 vii

List of Figures Figure.1 Road Map for the Proof............................. 8 viii

Chapter 1 Introduction Fractional factorials are widely employed in areas of science and technology owing to their flexibility and run size economy. The primary problem for us to use these designs is how to choose an optimal design for a given number of factors and run size. Various criteria have been suggested to deal with this problem, but it seems impractical to provide optimal designs for each criterion. The most popular criterion for comparing regular fractional factorials is minimum aberration, introduced by Fries and Hunter (1980). A generalization of this criterion, called minimum G -aberration, was proposed by Tang and Deng (1999) for comparing both regular and nonregular fractional factorials. Although minimum aberration designs are completely known for up to 18 runs, results for more than 18 runs are quite limited. Minimum G -aberration designs are available for up to 96 runs and in fact only partially available for more than 3 runs. This project presents a simple and efficient approach to constructing a good large design using two small minimum G -aberration designs. We focus on orthogonal factorials with two levels, which can be classified into two categories, regular fractional factorials and nonregular fractional factorials. A regular fractional factorial m p, having m factors of two levels, m p independent factors, and m p runs, is determined by its defining relation which contains p independent defining words. Regular designs have a property that any two effects are either orthogonal or fully aliased. In contrast to a m p design, a nonregular fractional factorial has some complex aliasing structure, meaning that there exist two partially aliased effects. Tang and Deng (1999) provided a formal definition for both regular and nonregular factorials, which is introduced in Section 1.1. The rest of this chapter reviews J-characteristics, orthogonal factorials, and the criteria of minimum aberration and minimum G -aberration. Chapter proposes our approach to constructing a large design using two smaller designs, and then studies some relationships between the large design and the two small designs. The results are presented in Sections.-.4. For Chapter 3, the general applications of the results derived in Chapter are discussed in Section 3.1. We then use a specific case to assess the goodness of designs constructed by our 1

approach. We construct regular 64-run factorials with 7 m 63 factors using the approach suggested in Section.1. For each number m of factors, we choose a design with the least aberration from those constructed designs as the best one, and compare it with the minimum aberration design. Chapter 4 summarizes this project and discusses some possible future work. 1.1 Notation and Background Suppose design D is an orthogonal fractional factorial (regular or nonregular) with m factors and n runs. For convenience, we write D as a set of m columns, D = {d 1,..., d m }, or an n m matrix, D = (d ij ), where d ij { 1, 1}. For 1 k m and any k-subset u = {d j1,..., d jk } of D, Deng and Tang (1999) defined n J k (u) = J k (d j1,..., d jk ) = d ij1 d ijk, (1.1) i=1 where d ij1 is the ith component of column d j1. J 0 (ϕ) = n was also defined. Here, J 1 (u) = J (u) = 0, as the numbers of the two levels in any column of D are identical, and any two columns are orthogonal in D. Tang and Deng (1999) summarized the J k (u) values in the following definition. Definition 1.1.1. The J k (u) values in (1.1) are called the J-characteristics of design D. According to (1.1), we have the following fact, which will be used in the proofs of the theorems in Sections.-.4. Fact 1.1.1. For any k-subset u = {d j1,..., d jk } of D and a column d {d 1,..., d m } in D, we have (a) J k+1 (d j1,..., d jk, I n ) = J k (d j1,..., d jk ), (b) d h = d } {{ d } = h I n d if h is even, if h is odd, (c) n if h is even, J h+1 (d,..., d, I }{{} n ) = J h (d,..., d) = }{{} 0 if h is odd, h h (d) J k (d j1,..., d jk ) J k+h (d j1,..., d jk, d,..., d) = }{{} J h k+1 (d j1,..., d jk, d) if h is even, if h is odd,

where I n is the identity column of length n with all 1 s. Based on the J-characteristics of D, Deng and Tang (1999) introduced the notion of generalized resolution. Let r be the smallest integer such that max u =r J r (u) > 0, where the maximization is over all the subsets of r distinct columns of D. Then the generalized resolution of design D is defined to be R(D) = r + [ 1 max u =r J r(u)/n ]. (1.) Clearly, r R(D) < r + 1. Note that R(D) 3 for orthogonal designs, as J 1 (u) = J (u) = 0. For a regular design D, J k (u) = n or 0, as effects in u are either fully aliased or orthogonal. But, for a nonregular factorial, there exists a u such that 0 < J k (u) < n. According to the values of J-characteristics, Tang and Deng (1999) gave a formal definition for regular and nonregular designs. Definition 1.1.. A fractional factorial D is said to be regular if J k (u) = n or 0 for all u D. It is said to be nonregular if there exists a u D such that 0 < J k (u) < n. It is clear that the defining relation of a regular design D is the collection of all subsets u s such that J k (u) = n for k = 1,..., m. This means that if there exists a k such that J k (u) = n, then a word in the defining relation is formed by those k columns in u. Let A k (D) be the number of words of length k in the defining relation, and then the word length pattern of design D is defined as the vector, W (D) = (A 1 (D), A (D), A 3 (D),..., A m (D)). Obviously, A 1 (D) = A (D) = 0. For two regular factorials D 1 and D with the same number of factors and run size, the minimum aberration is utilized to compare them. Let r be the smallest integer such that A r (D 1 ) A r (D ). If A r (D 1 ) < A r (D ), then D 1 is said to have less aberration than D. If no design has less aberration than D 1, then we say that D 1 has minimum aberration. The minimum G -aberration, a generalization of the minimum aberration, is used to assess the goodness of general fractional factorials. For a design D, let B k (D) = 1 n Jk (u) = 1 n Jk (d j1,..., d jk ), for 1 k m, (1.3) u =k 1 j 1 < <j k m where B 1 (D) = B (D) = 0. For two factorials D 1 and D, let r be the smallest integer such that B r (D 1 ) B r (D ). If B r (D 1 ) < B r (D ), then D 1 is said to have less G -aberration than D. If no design has less G -aberration than D 1, then we say that D 1 has minimum G -aberration. If D is a regular factorial, then B k (D) = A k (D), which implies that minimum G -aberration is 3

equivalent to minimum aberration for regular designs. For 1 k m, Butler (003) defined M k (D) = 1 n m m Jk (d j1,..., d jk ), for 1 k m. (1.4) j 1 =1 j k =1 Clearly, M k (D) is greater than B k (D), as it considers all permutations for each collection of k columns and also allows columns to occur in {d j1,..., d jk } more than once. The quantity M k (D) is instrumental in determining the constants in the theorems of Sections.3 and.4. 4

Chapter General Theoretical Results.1 Constructing A Large Design Using Two Small Designs We firstly review some basic definitions. Let x = (x 1,..., x n1 ) T and y = (y 1,..., y n ) T. The Kronecker product of two vectors x and y is defined as x y = (x 1 y 1,..., x 1 y n,..., x n1 y 1,..., x n1 y n ) T. Tang (006) provided a simple way to calculate the J-characteristic of Kronecker products. Lemma.1.1. We have that J(a 1 b 1,..., a k b k ) = J(a 1,..., a k )J(b 1,..., b k ), where a j = (a 1j,..., a n1 j) T and b j = (b 1j,..., b n j) T for j = 1,..., k. Let D 1 and D be two factorials, either regular or nonregular. Design D 1 is an n 1 -run design with m 1 factors and can be expressed by a set of m 1 columns, D 1 = {a 1,..., a m1 }. Similarly, D has m factors and n runs, and can be written as a set of m columns, D = {b 1,..., b m }. A large design D can then be obtained by taking the Kronecker product of two designs D 1 and D, D = D 1 D = {a 1,..., a m1 } {b 1,..., b m } = {a 1 b 1,..., a 1 b m,..., a m1 b 1,..., a m1 b m }. (.1) Clearly, design D is a factorial with m factors and n runs, where m = m 1 m and n = n 1 n. Moreover, D is a regular factorial if both D 1 and D are regular. Otherwise, D is a nonregular factorial. 5

For any k-subset u = {a i1 b j1,..., a ik b jk }, where 1 k m, by Lemma.1.1, we have J k (u) = J k (a i1 b j1,..., a ik b jk ) = J k (a i1,..., a ik ) J k (b j1,..., b jk ). (.) Here, since each column in D is the Kronecker product of a column from D 1 and one from D and the total number of columns in D is m 1 m, for any a i {a 1,..., a m1 } and b j {b 1,..., b m }, the numbers of a i and b j contributing to D are m 1 and m, respectively. Hence, for an arbitrary k-subset u = {a i1 b j1,..., a ik b jk } with 1 k m, each of the collections {a i1,..., a ik } and {b j1,..., b jk } in (.) may contain some repeated columns. This observation is important for the proofs in the following sections of this chapter.. Doubling Doubling is a special case of the construction in (.1), where [ ] 1 1 D 1 =. (.3) 1 1 Here, design D 1 only has two columns a 1 = (1, 1) T and a = ( 1, 1) T. Design D is an ordinary factorial, either regular or nonregular, with m factors and n runs. The double of D is then defined as D = D 1 D [ ] D D =. (.4) D D Clearly, design D has m = m factors and n = n runs. If D is regular, Chen and Cheng (006) derived a relationship between the word-length pattern of D and that of its corresponding D, which is given in Theorem..1. The same relationship also holds for nonregular designs but it does require a new proof. Theorem..1. Suppose k is a positive integer with 1 k m. Then B k (D) = 0 if k {1, }, (k 3)/ (k 3)/ k t 1( m (k t) t k t 1( m (k t) t ) Bk t (D ) + ( m ) k/ ) Bk t (D ) otherwise, if k is a multiple of 4, (.5) where x is the largest integer less than or equal to x. 6

Proof. It is obvious that B 1 (D) = B (D) = 0, as J 1 = J = 0 for any orthogonal design D. For 3 k m, since there are only columns in D 1, each column in {b j1,..., b jk } occurs at most twice when we calculate J k (u) in (.). Let t be the number of columns occurring exactly twice in {b j1,..., b jk }. We have that the remaining (k t) columns in {b j1,..., b jk }, different from the above t columns, are all distinct. This implies that there are ( m (k t) ) t ways to choose the repeating columns for each {b j1,..., b jk }. By part (d) of Fact 1.1.1, we then have that J k (b j1,..., b jk ) = ( m (k t) ) ( ) t Jk t bj1,..., b jk t. On the other hand, design D1 in (.3) gives J k (a i1,..., a ik ) = 0 or, and J k (a i1,..., a ik ) =, only if the number of a = ( 1, 1) T in {a i1,..., a ik } is even. As there are t columns occurring twice in {b j1,..., b jk }, column a is included in {a i1,..., a ik } at least t times. We then study two situations, (a) t is even and (b) t is odd, although the final results are the same for both situations. For situation (a), since t is even, the number of a s which correspond to k t distinct columns in {b j1,..., b jk } is even for otherwise J k (u) = 0. Then the total number of ways to choose the number of a s is ( k t) ( 0 + k t ) ( + k t ) 4 + = k t /. Resembling situation (a), the number of a s which correspond to k t distinct columns is odd, as t is odd in situation (b). Then there are ( k t ) ( 1 + k t ) ( 3 + k t ) 5 + = k t / ways to choose the number of a s. As J 1 = J = 0 for any ( ) orthogonal design D, t must satisfy k t 3 in order to have J k t bj1,..., b jk t > 0. Since t is a nonnegative integer, we have t [0, (k 3)/], if k is odd, and t [0, (k 4)/], if k is even. We have two cases: (i) k is odd, and (ii) k is even. For any k-subset u = {a i1 b j1,..., a ik b jk }, where 3 k m, case (i) gives B k (D) = 1 (n ) u =k = 1 (n ) (k 3)/ = (k 3)/ = u =k k t / k t / J k (u) J k (a i1,..., a ik ) J k (b j1,..., b jk ) ( ) m (k t) 1 t ( m (k t) t n Jk t 1 j 1 < <j k t m ) ( bj1,..., b jk t ) B k t (D ), (.6) For case (ii), except for a similar term like (.6), B k (D) contains an extra constant term for an even k/, as there exists t = k/ under (ii) such that k t = 0. This implies that there are k/ distinct columns in {b j1,..., b jk }, each column occurring twice. We then have that the number of a s in {a i1,..., a ik } is exact k/. Since J k (b j1,..., b jk ) = n by part (c) of Fact 1.1.1, and J k (a i1,..., a ik ) = n 1 = > 0 only when k/ is even, a non-zero constant term exists only when k/ is even. The number of ways to choose those k/ columns is ( m k/). The final result for an even k/ is B k (D) = (k 4)/ ( ) k t m (k t) / B k t (D ) + t Combining (.6) and (.7), Theorem..1 is obtained. ( ) m. (.7) k/ 7

Using Theorem..1, detailed expressions for B 3 (D), B 4 (D) and B 5 (D) are easily obtained, which are shown below B 3 (D) = 4B 3 (D ), (.8) ) B 4 (D) = 8B 4 (D ) + and ( m, (.9) B 5 (D) = 16B 5 (D ) + 4(m 3)B 3 (D ). (.10) These equations will be used in the next chapter..3 Small Design Without A Column of 1 s Design D in Section. has a restriction in that it can only double the number m of factors and the run size n of the original design D. This implies that the number m of factors and the run size n of D are fixed for given m and n of D. To make m and n more flexible, we construct D by using a general design D 1. Design D 1 discussed in this section is any factorial, with the only requirement that it does not contain a column of all 1 s. Note that we always assume D does not have a column of all 1 s. As D 1 is relaxed, B k (D) is also related to B s (D 1 ) for s k. A relationship can be established among B s (D 1 ), B t (D ) and B k (D) for s, t k, which is shown in the following theorem. Theorem.3.1. Suppose k is a positive integer with 1 k m 1 m. Then 0 if k {1, }, l l B k (D) = C st B k s (D 1 )B k t (D ) if k 3 is odd, l l l l C st B k s (D 1 )B k t (D ) + C s (1) B k s (D 1 ) + C () t B k t (D ) + C if k 3 is even, (.11) where l = (k 3)/, and C 00 > 0. All constants in (.11) depend on m 1, m, n 1, n, not on choices of D 1 and D for given m 1, m, n 1, n. B k (D 1 ) and B k (D ) B k (D) I III M k (D 1 ) and M k (D ) II M k (D) Figure.1: Road Map for the Proof 8

Proof. Obviously, B 1 (D) = B (D) = 0. For 3 k m 1 m, instead of directly studying a relationship of B k s among designs D 1, D and D, we separate it into three steps I, II, and III, which is shown in Figure.1. Step I connects B k (D 1 ) and B k (D ) with M k (D 1 ) and M k (D ), respectively. Step II links M k (D 1 ) and M k (D ) with M k (D). Since M k considers all permutations for each collection of k columns and allows the columns occurring more than once in each collection, the relationship in Step II is straightforward and given by M k (D) = M k (D 1 )M k (D ), for 1 k m 1 m. (.1) The last step gives a connection between M k (D) and B k (D). In practice, two relationships in Step I are identical and the inverse of this relationship is what Step III needs, as D 1, D and D are general factorials without a column of 1 s. Hence, we choose design D to study this relationship. Let t be the number of columns occurring more than once in {b j1,..., b jk }, say columns b jk t +1,..., b jk, and h g be the number of b jg s in {b j1,..., b jk } for k t + 1 g k. We then consider two situations, (i) all h g s are even, and (ii) at least one h g is odd. Situation (i) gives that there exists a t such that k g=k t +1 h g = t. We then have b h k t +1 j k t +1 b h k j k = I n by part (d) of Fact 1.1.1, which implies that J k (b j1,..., b jk ) = J k t ( bj1,..., b jk t ). For situation (ii), suppose h k t +1,..., h g are odd, where g can be any number in {k t + 1,..., k}. Then there exists a t such that g g=k t +1 (h g 1) + k g h g = k g=k t +1 h g (g k + t ) = t. By part (b) of Fact 1.1.1, we then obtain b h k t +1 j k t +1 b h k j k = b jk t +1 b jg, and J k (b j1,..., b jk ) = ) ( ) J k t (b j1,..., b jk, b jk t hg +1,..., b jg = J k t bj1,..., b jk t. Both situations (i) and (ii) give that J k are related to J k t s with 3 k t k. We consider two cases. Case (1): k is odd. We then have M k (D ) = 1 m m n Jk (b j1,..., b jk ) j 1 =1 j k =1 = = (k 3)/ (k 3)/ C () t 1 n 1 j 1 < <j k t m Jk t ( ) bj1,..., b jk t C () t B k t (D ), (.13) where C () t is a positive constant, as C () t is the product of two numbers, the number of ways to choose the repeating columns and that of ways to permute k columns in each collection. Similarly, for D 1 and D, we have M k (D 1 ) = M k (D) = (k 3)/ (k 3)/ v=0 C (1) s B k s (D 1 ), (.14) C (3) v B k v (D), (.15) 9

where Cs (1) and Cv (3) are positive constants for 0 s, v (k 3)/. Using (.1), a recursion formula for an odd k is obtained (k 3)/ v=0 (k 3)/ Cv (3) B k v (D) = = (k 3)/ (k 3)/ Cs (1) B k s (D 1 ) (k 3)/ C () t B k t (D ) C stb k s (D 1 )B k t (D ). (.16) A formula for B k (D) can then be obtained from the above recursion formula, B k (D) = (k 3)/ (k 3)/ C st B k s (D 1 )B k t (D ), (.17) where C 00 is a positive coefficient for the leading term B k (D 1 )B k (D ) for 3 k m 1 m, as can be verified by induction. For k = 3, using (.16), it is obvious that B 3 (D) = C 00 C (3) 0 B 3 (D 1 )B 3 (D ) with C 00 > 0. For k > 3, let k be the maximum odd number in the range [3, m C (3) 1 m ]. Suppose 0 that (.17) with a positive C 00 is true for k (k ). For k = k, using (.16), we have C (3) 0 B k (D) = (k 3)/ (k 3)/ = C 00B k (D 1 )B k (D ) (k 3)/ + + (k 3)/ s=1 (k 3)/ CstB k s(d 1 )B k t(d ) (k 3)/ C0tB k (D 1 )B k t(d ) + (k 3)/ t=1 v=1 (k 3)/ CstB k s(d 1 )B k t(d ) Cv (3) B k v(d) C s0b k s(d 1 )B k (D ) v=1 (k 3)/ = C00B k (D 1 )B k (D ) + C0tB k (D 1 )B k t(d ) (k 3)/ + (k 3)/ v=1 C s0b k s(d 1 )B k (D ) + C (3) v (k v 3)/ (k v 3)/ (k 3)/ s=1 (k 3)/ t=1 Cv (3) B k v(d) C stb k s(d 1 )B k t(d ) C stb k v s(d 1 )B k v t(d ) (k 3)/ = C00B k (D 1 )B k (D ) + C0tB k (D 1 )B k t(d ) = (k 3)/ + (k 3)/ C s0b k s(d 1 )B k (D ) + (k 3)/ (k 3)/ s=1 (k 3)/ t=1 C st B k s(d 1 )B k t(d ) C st B k s(d 1 )B k t(d ), (.18) 10

where C00 = C 00 > 0. As the coefficient C (3) 0 of B k (D) is positive, equation (.17) is true for 3 k k. Case (): k is even. There exist some t s such that k g=k t +1 h g = t = k, which implies that J k (b j1,..., b jk ) = n, only if all h g s are even. Let m be the number of values of t, we then obtain M k (D ) = = (k 4)/ (k 4)/ C () t B k t (D ) + m t =1 C t, C () t B k t (D ) + C, (.19) where C t is the number of ways to choose the t columns. Similar to the case of odd k, M k (D 1 ) and M k (D) can be easily written as where C (1) s (k 4)/ v=0 M k (D 1 ) = M k (D) = (k 4)/ (k 4)/ v=0 C (1) s B k s (D 1 ) + C 1, (.0) C (3) v B k v (D) + C, (.1) and C (3) v are positive constants. A recursive formula is derived using (.1), C (3) v B k v (D) + C = By induction, the formula for each B k (D) with an even k is B k (D) = k 4 k 4 (k 4)/ (k 4)/ Cs (1) B k s (D 1 ) + C 1 C () t B k t (D ) + C. C st B k s (D 1 )B k t (D )+ k 4 C (1) s B k s (D 1 )+ k 4 C () t B k t (D )+C, (.) where C 00 > 0. We then arrive at (.11) with a positive coefficient of the leading term B k (D 1 )B k (D ) for 3 k m 1 m. Obviously, it is hard to determine the constants in (.11) explicitly for all s and t. Here, we only focus on the cases of k = 3, 4, 5, as they are useful in Chapter 3. The simplest case is k = 3. It is evident that M 3 (D 1 ) = 3!B 3 (D 1 ), as M 3 considers the permutations of columns in {a i1, a i, a i3 }. Similarly, we have M 3 (D ) = 3!B 3 (D ), (.3) and M 3 (D) = 3!B 3 (D). (.4) 11

Using (.1) we obtain B 3 (D) = 3!B 3 (D 1 )B 3 (D ). (.5) For k = 4, by equation (.0), we have M 4 (D 1 ) = C (1) 0 B 4 (D 1 ) + C 1 (( 4 = 4!B 4 (D 1 ) + ) = 4!B 4 (D 1 ) + 6 ( m1 )( ) m1 + ( )) m1 1 + m 1, (.6) where 4! is the number of ways to permute four distinct columns in {a i1, a i, a i3, a i4 }, ( 4)( m1 ) is the product of two numbers, the number of ways to choose two distinct columns and that to permute four columns, and ( m 1 1 and D, we obtain ) is the number of ways to choose one column. Similarly for D M 4 (D ) = 4!B 4 (D ) + 6 ( ) m + m, (.7) and ( ) m M 4 (D) = 4!B 4 (D) + 6 + m. (.8) Again using (.1) and after some algebraic calculation, we derive that B 4 (D) =4!B 4 (D 1 )B 4 (D ) + + ( m + 6 ( )) m Clearly, using equation (.14) with k = 5, we get ( m 1 + 6 B 4 (D 1 ) + ( )) m1 B 4 (D ) ( )( ) m1 m M 5 (D 1 ) = C (1) 0 B 5 (D 1 ) + C (1) 1 B 3 (D 1 ) = 5!B 5 (D 1 ) + C (1) 1 B 3 (D 1 ),. (.9) where 5! is the number of the ways to permute five distinct columns in each subset. For the second term in the above equation, it is obvious that there must be only one column occurring at least twice, say columns a i4 = a i5. Two situations are possible: (i) there exists a h such that a i4 = a ih, where h = 1,, 3, and (ii) a i4 a ih for h = 1,, 3. For situation (i), there are ( 3) 1 ways to choose a column from {a i1, a i, a i3 }, and ( 5 3)( 1) ways to permute those five columns. Situation (ii) has ( m 1 3) 1 ways to choose a column from the set without columns ai1, a i, and a i3, and has ( 5 ) 3! ways to permute those five columns. We thus have 1

M 5 (D 1 ) = 5!B 5 (D 1 ) + Obviously, M 5 (D ) and M 5 (D) are (( )( )( ) 3 5 1 3 1 ( )( ) ) m1 3 5 + 3! B 3 (D 1 ) 1 = 5!B 5 (D 1 ) + 60(m 1 )B 3 (D 1 ). (.30) M 5 (D ) = 5!B 5 (D ) + 60(m )B 3 (D ), (.31) and Finally, some simple algebra leads to M 5 (D) = 5!B 5 (D) + 60(m )B 3 (D). (.3) B 5 (D) = 5!B 5 (D 1 )B 5 (D ) + 60(m )B 5 (D 1 )B 3 (D ) + 60(m 1 )B 3 (D 1 )B 5 (D ) + (7m 1 m 60m 1 60m + 16)B 3 (D 1 )B 3 (D ). (.33).4 Small Design with A Column of 1 s Design D 1 discussed in this section contains one column of 1 s which is the identity column I n1. This implies that design D constructed by such a D 1 has extra m columns. We also derive a similar relationship among B s (D 1 ), B t (D ), and B k (D) for s, t k, which is shown in the following theorem. Theorem.4.1. Suppose k is a positive integer with 1 k m 1 m. Then 0 if k {1, }, k 3 l l B k (D) = C st B k s (D 1 )B k t (D ) + C () t B k t (D ) if k 3 is odd, k 3 l l C st B k s (D 1 )B k t (D ) + C () k 3 t B k t (D ) + C s (1) B k s (D 1 ) + C if k 3 is even, (.34) where l = (k 3)/, and C 00 > 0. All constants in (.34) depend on m 1, m, n 1, n, not on choices of D 1 and D for given m 1, m, n 1, n. Proof. This proof is similar to that of Theorem.3.1. As D 1 contains column I n1, M k (D 1 ) depends on all B k s (D 1 ) for 0 s k 3. A constant term always exists, regardless of the parity of k, because of a special collection with length k, {I n1,..., I n1 }. We then have M k (D 1 ) = (k 3) C (1) s B k s (D 1 ) + C, (.35) 13

where Cs (1) is a positive constant, as it is the product of two numbers, the number of ways to choosing the repeating columns and that of ways to permute columns in the corresponding collection. Since D and D are two ordinary orthogonal designs, the expressions for M k derived in the proof of Theorem.3.1 are still valid. M k (D ) and M k (D) with an odd k are shown in (.13) and (.15) with positive coefficients, respectively. For an even k, equations (.19) and (.1) with positive coefficients are also the expressions for M k (D ) and M k (D) in this section, respectively. Using (.1), recursive formulas are (k 3)/ Cv (3) k 3 (k 3)/ B k v (D) = C (1) s B k s (D 1 ) + C C () t B k t (D ) if k is odd, v=0 (k 4)/ Cv (3) k 3 (k 4)/ B k v (D) + C = Cs (1) B k s (D 1 ) + C C () t B k t (D ) + C if k is even. v=0 Using induction for odd k s and even k s respectively, we obtain k 3 B k (D) = k 3 (k 3)/ (k 4)/ C st B k s (D 1 )B k t (D ) + C st B k s (D 1 )B k t (D ) + (k 3)/ (k 4)/ C () t B k t (D ) if k is odd, C () t B k t (D ) + k 3 C (1) s B k s (D 1 ) + C if k is even, where C 00 > 0 for both odd k s and even k s. Here, we also determine the constants in B k (D) using M k of the corresponding designs D 1, D and D for k = 3, 4, 5. Clearly, M k (D ) and M k (D) for k = 3, 4, 5 were given in Section.3, as D and D are factorials without one column of 1 s. For design D 1 with one column of 1 s, M k (D 1 ) with k = 3, 4, 5 are derived as follows. For k = 3, using (.35), we have M 3 (D 1 ) = C (1) 0 B 3 (D 1 ) + C, where C (1) 0 = 3!, as the number of ways to permute three distinct columns in each subset is 3!. The term C considers the collection {a i1, a i, a i3 } with repeating columns. As there are only three columns in each collection, two situations should be studied, (i) a column occurs twice, and (ii) a column occurs 3 times. For situation (i), J 3 (a i 1, a i, a i3 ) > 0, only when each collection {a i1, a i, a i3 } contains one column I n1 apart from two identical columns. There are (m 1 1) ways to choose the identical column and ( 3 1) ways to permute those three columns. For situation (ii), J3 (a i 1, a i, a i3 ) > 0, only when each collection {a i1, a i, a i3 } contains three I n1 s. 14

We then obtain M 3 (D 1 ) = 3!B 3 (D 1 ) + (( ) ) 3 (m 1 1) + 1 1 = 3!B 3 (D 1 ) + 3(m 1 1) + 1. Combining this equation with (.3) and (.4), we have For k = 4, we obtain B 3 (D) = 3!B 3 (D 1 )B 3 (D ) + (3m 1 )B 3 (D ). (.36) M 4 (D 1 ) = C (1) 0 B 4 (D 1 ) + C (1) 1 B 3 (D 1 ) + C. Obviously, C (1) 0 = 4!. As each collection of B 3 (D 1 ) contains one column I n1 which is different from the other three distinct columns, there are 4! ways to permute those four columns. The last term is from the collections which have the repeating columns. Let h be the number of columns occurring more than once. Clearly, h = 1,. For h = 1, J 4 (a i 1,..., a i4 ) > 0, only when a i1 = a ig for g =, 3, 4. There are m 1 distinct columns which can be used to form such collections. For h =, since there are four columns in each collection, each column occurs exactly twice. the number of ways to choose two distinct columns is ( m 1 ) (. There are 4 ) ways to permute columns in each collection. We thus obtain M 4 (D 1 ) = 4!B 4 (D 1 ) + 4!B 3 (D 1 ) + = 4!B 4 (D 1 ) + 4!B 3 (D 1 ) + ( ( m 1 + m 1 + 6 Using (.7) and (.8), B 4 (D) has the following expression: B 4 (D) = 4!B 4 (D 1 )B 4 (D ) + 4!B 3 (D 1 )B 4 (D ) + + ( m + 6 For k = 5, it is obvious that ( )) m ( (B 4 (D 1 ) + B 3 (D 1 )) + ( )( )) m1 4 ( m1 m 1 + 6 )). ( )) m1 ( )( ) m1 m M 5 (D 1 ) = C (1) 0 B 5 (D 1 ) + C (1) 1 B 4 (D 1 ) + C (1) B 3 (D 1 ) + C. B 4 (D ). (.37) Clearly, C (1) 0 = C (1) 1 = 5!. The term C (1) B 3 (D 1 ) is identical to the second term 60(m 1 )B 3 (D 1 ) in (.30). The interpretation of the coefficient of B 3 (D 1 ) was also given in Section.3. For the constant term, we let h be the number of I n1 s. Since there are five columns in a collection, h is odd, clearly h = 1, 3, 5. For h = 1 there are two cases, (a) the remaining four columns are identical, (b) not all of them are the same. Case (a) gives (m 1 1) ways to choose a 15

repeating column and ( 5 4) ways to permute those five columns in each collection. Case (b) shows that J5 (a i 1,..., a i5 ) > 0, only when two distinct columns occur exact twice. There are ( m 1 1) ways to choose two distinct columns and ( 5 3 )( ) ways to permute those five columns. For h = 3, in order to obtain J5 (a i 1,..., a i5 ) > 0, the left two columns in the collection must be the same. The number of ways to choose a column is ( m 1 1) ( 1 and there are 5 ) ways to permute those five columns. It is obvious that only J5 (I n 1,..., I n1 ) > 0 for h = 5. M 5 (D 1 ) can then be obtained M 5 (D 1 ) = 5!B 5 (D 1 ) + 5!B 4 (D 1 ) + 60(m 1 )B 3 (D 1 ) (( )( ) ( )( )( ) ( )( ) ) m1 1 5 m1 1 5 3 m1 1 5 + + + + 1 1 4 1 ( ) m1 1 = 5!B 5 (D 1 ) + 5!B 4 (D 1 ) + 60(m 1 )B 3 (D 1 ) + 30 + 15m 1 14 Combining the above with (.31) and (.3), we get that B 5 (D) = 5!B 5 (D 1 )B 5 (D ) + 5!B 4 (D 1 )B 5 (D ) + 60(m ) (B 5 (D 1 ) + B 4 (D 1 )) B 3 (D ) ( ( ) ) m1 1 + 60(m 1 )B 3 (D 1 )B 5 (D ) + 30 + 15m 1 14 B 5 (D ) + (7m 1 m 60m 1 60m + 16)B 3 (D 1 )B 3 (D ) + (6m 1m 15m 1 14m 1 m + 33m 1 + 8m 18)B 3 (D ). (.38) These three quantities B 3 (D), B 4 (D) and B 5 (D) play an important role in the next chapter. 16

Chapter 3 Applications 3.1 Generals Section.1 presents a simple approach to constructing a large design using two small designs. But, it may be computationally difficult or impractical to assess the goodness of this large design using minimum G -aberration by directly evaluating values of the associated B k for 1 k m. The properties derived from Sections.-.4 provide us with a simple way to achieve this. Theorem..1 shows that B k (D) of the doubled design D is a linear combination of B k (D ), B k (D ),... of the original design D, with a positive coefficient for the leading term B k (D ). Theorem.3.1 says that B k (D) of design D is a linear combination of B k (D 1 )B k (D ), B k (D 1 ) B k (D ),... of the original designs D 1 and D, with a positive coefficient for the leading term B k (D 1 )B k (D ). Resembling Theorem.3.1, Theorem.4.1 states that B k (D) is a linear combination of B k (D 1 )B k (D ), B k (D 1 )B k (D ),... of the original designs D 1 and D, with a positive coefficient for the leading term B k (D 1 )B k (D ). These results imply that if we choose D 1 and D with small B k s, the corresponding D also has small B k (D) s. A design with small B k s can then be obtained using two small minimum G -aberration designs. Specific expressions for the B 3 (D) value in Theorems..1,.3.1, and.4.1 are given in (.8), (.5), and (.36), respectively. The corresponding B 4 (D) s are presented in (.9), (.9), and (.37). We note that in each case, B 3 (D) depends on B 3 (D ). However, each B 4 (D) contains a constant term. If we choose a design D with B 3 (D ) = 0, then we obtain the corresponding D with B 3 (D) = 0, which means that our approach can construct a large design with 4 R(D) < 5 using a smaller design D with R(D ) 4, where R(D) and R(D ) are the generalized resolutions of D and D, respectively. We note that R(D ) 4 requires some restriction on the number of factors and the run size. It is well known that design D with R(D ) 4 exists, only if m n /. This implies that given a run size n, design D must have 4 R(D) < 5, if the number of factors is small. On the other hand, D has 3 R(D) < 4, if the number of factors is large. In most cases, B 3 (D), B 4 (D), and B 5 (D) are enough to compare D s for a given m and n. 17

In the next two sections, we use regular designs with 7 m 63 factors and 64 runs to illustrate our approach. 3. Regular 64-Run Designs with 7 m 63 Factors In order to evaluate our approach, the best design from our approach must be found for each m value. According to the value of m, we consider two situations, (i) m is a composite number; and (ii) m is a prime. Designs under situation (i) can be constructed by our approach directly. For each composite number m, we consider all possible combinations of D 1 and D that satisfy m 1 m = m and n 1 n = 64. For each combination, we use the corresponding minimum aberration designs D 1 and D. Based on the type of D 1, three components (A 3 (D), A 4 (D), A 5 (D)) of the word length pattern can be computed using the associated results in Sections.-.4. We then compare all the resulting designs by the minimum aberration criterion, and the design with the least aberration is the best design from our approach. This best design is then compared with the corresponding minimum aberration design in Section 3.3. For instance, for m = 4, all the possible small designs, D 1 and D that satisfy m 1 m = 4 and n 1 n = 64, are given in Table 3.1, where D(i) is the saturated design of i independent factors with a column of 1 s added. This table also contains A 3, A 4, A 5 values of the minimum aberration designs D 1 and D in each combination, respectively. The corresponding (A 3, A 4, A 5 ) of design D is computed and given in the last column of Table 3.1. Obviously, design D with (A 3 (D), A 4 (D), A 5 (D)) = (0, 370, 0) has the least aberration, and is the best design for m = 4 from our approach. Table 3.1: All possible D 1 s and D s for designs 4 18 Number of Factors Runs D D 1 D D m 1 m n 1 n D 1 D (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) 1 4 16 [ ] 1 8 (0, 0, 0) (16, 39, 48) (0, 378, 0) 1 1 3 1 1 1 7 (0, 0, 0) (0, 38, 0) (0, 370, 0) 4 6 8 8 4 1 6 3 (0, 1, 0) (4, 3, 0) (0, 378, 0) 4 16 D() 6 (1, 0, 0) (0, 30, 0) (0, 378, 0) 8 3 8 8 D(3) 3 (7, 7, 0) (0, 0, 0) (0, 378, 0) 16 4 8 4 3 1 (0, 14, 0) (1, 0, 0) (0, 378, 0) For prime values of m, our approach does not apply directly. In this case, a design with a prime number m of factors can be obtained by the method of deleting one column from a design with m + 1 factors, which can be constructed by our approach. It can be done as follows. 18

Each time we delete one column from the best design constructed with m + 1 factors, we then compute A 3, A 4, A 5 values of the design containing the remaining columns. Obviously, the total number of designs with m factors is m + 1. The best design with m factors having the least aberration is then found by comparing all those m + 1 designs. Table 3.: (A 3, A 4, A 5 ) s of the best designs from our approach with 7 m 63 factors Number of Factors (A 3, A 4, A 5 ) Number of Factors (A 3, A 4, A 5 ) 7 (0, 3, 0) 36 (64, 1337, 4544) 8 (0, 6, 0) 37 (80, 1401, 5760) 9 (0, 9, 0) 38 (96, 1483, 7040) 10 (0, 10, 0) 39 (11, 1579, 8400) 11 (0, 10, 0) 40 (18, 1694, 9856) 1 (0, 15, 0) 41 (144, 18, 1143) 13 (0, 19, 4) 4 (160, 1970, 13136) 14 (0, 9, 3) 43 (176, 146, 14960) 15 (0, 30, 60) 44 (19, 335, 16960) 16 (0, 5, 64) 45 (10, 50, 1915) 17 (0, 64, 96) 46 (4, 773, 1504) 18 (0, 84, 18) 47 (40, 305, 4080) 19 (0, 100, 19) 48 (56, 3300, 6880) 0 (0, 15, 56) 49 (94, 3479, 9841) 1 (0, 10, 0) 50 (304, 3836, 33184) (0, 55, 0) 51 (38, 4140, 36744) 3 (0, 307, 0) 5 (35, 4469, 40608) 4 (0, 370, 0) 53 (376, 481, 44800) 5 (0, 438, 0) 54 (400, 5199, 49344) 6 (0, 518, 0) 55 (44, 5603, 5464) 7 (0, 606, 0) 56 (448, 6034, 59584) 8 (0, 707, 0) 57 (476, 648, 6540) 9 (0, 819, 0) 58 (504, 6958, 71344) 30 (0, 945, 0) 59 (53, 746, 7794) 31 (0, 1085, 0) 60 (560, 7995, 85008) 3 (0, 140, 0) 61 (590, 8555, 9568) 33 (16, 140, 110) 6 (60, 9145, 100688) 34 (3, 156, 40) 63 (651, 9765, 109368) 35 (48, 188, 3376) This delete-one-column method is in fact quite versatile. It can also be applied when m is a composite number, and can sometimes produce better designs than the direct method. Table 3. provides three components (A 3 (D), A 4 (D), A 5 (D)) of the word length pattern of the best design for each 7 m 63 found by our method. The entries with a " " identify those cases where the designs are found using the delete-one-method. Noteworthy are the entries for m = 5, 7, 33, 35, 39, 51, 55, and 57. Although these m values are composite, the best designs given in the table are actually obtained using the method of deleting one column. 19

3.3 Comparison with Minimum Aberration Designs To assess the goodness of the best designs constructed from our approach, we compare them with the corresponding minimum aberration designs. We separately consider two ranges of m values, 7 m 3 and 33 m 63. The complete catalogue for regular 64-run designs with 7 m 3 factors of resolution 4 is available in Chen, Sun, and Wu (1993) and Xu (009). For designs with 33 m 63 factors, there is no summary available for the corresponding minimum aberration designs. Hence, we compute A 3, A 4, A 5 values for the minimum aberration designs with 33 m 63 factors, and then make a comparison. The complete catalogue for 7 m 3 includes three components (A 3, A 4, A 5 ) of the word length pattern for each nonisomorphic design with m factors, which is given in Table 3.3. The (A 3, A 4, A 5 ) values of the best designs from our approach are also given in Table 3.3. From this table, we see that (A 3, A 4, A 5 ) s of designs with m = 15, 19, 0 from our approach are identical to those of the corresponding minimum aberration designs. For m = 30, 31, and 3, the designs constructed by our approach are equivalent to the minimum aberration designs, which is because these designs are unique. Generally, as the m value increases, the result of (A 3, A 4, A 5 ) derived from our approach is getting closer to that from the minimum aberration design. Table 3.3: (A 3, A 4, A 5 ) s of minimum aberration (MA) designs and those of the corresponding best designs from our approach for 7 m 3 Number of Factors MA designs Constructed designs Number of Factors MA designs Constructed designs (m) (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) (m) (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) 7 (0, 0, 0) (0, 3, 0) 0 (0, 15, 56) (0, 15, 56) 8 (0, 0, ) (0, 6, 0) 1 (0, 04, 0) (0, 10, 0) 9 (0, 1, 4) (0, 9, 0) (0, 50, 0) (0, 55, 0) 10 (0,, 8) (0, 10, 0) 3 (0, 304, 0) (0, 307, 0) 11 (0, 4, 14) (0, 10, 0) 4 (0, 365, 0) (0, 370, 0) 1 (0, 6, 4) (0, 15, 0) 5 (0, 435, 0) (0, 438, 0) 13 (0, 14, 8) (0, 19, 4) 6 (0, 515, 0) (0, 518, 0) 14 (0,, 40) (0, 9, 3) 7 (0, 605, 0) (0, 606, 0) 15 (0, 30, 60) (0, 30, 60) 8 (0, 706, 0) (0, 707, 0) 16 (0, 43, 81) (0, 5, 64) 9 (0, 819, 0) (0, 819, 0) 17 (0, 59, 108) (0, 64, 96) 30 (0, 945, 0) (0, 945, 0) 18 (0, 78, 144) (0, 84, 18) 31 (0, 1085, 0) (0, 1085, 0) 19 (0, 100, 19) (0, 100, 19) 3 (0, 140, 0) (0, 140, 0) To make a comparison for designs with 33 m 63 factors, we firstly deduce (A 3, A 4, A 5 ) s of minimum aberration designs using the complementary designs. Let H be the saturated design of 64 runs for 63 factors, and D H be a design of m factors. The corresponding complementary design with m factors is denoted by D = H \D, where m = 63 m. Tang and Wu (1996) proved 0

that A 3 (D) = constant A 3 ( D), (3.1) A 4 (D) = constant + A 3 ( D) + A 4 ( D), (3.) and A 5 (D) = constant ( f 1 m)a 3 ( D) A 4 ( D) A 5 ( D), (3.3) where f is the number of independent factors. In our case, f = 6. The above equations give us a method of computing A 3 (D), A 4 (D), and A 5 (D) from A 3 ( D), A 4 ( D), and A 5 ( D). This raises the question of how to find the values of A 3 ( D), A 4 ( D), and A 5 ( D), if design D has minimum aberration. Tang and Wu (1996) also suggested a rule for identifying the minimum aberration designs. Rule 3.3.1. A design D has minimum aberration if: (i) A 3 ( D ) = max A 3 ( D) over all D = m, (ii) A 4 ( D { ) = min A 4 ( D) : A 3 ( D) = A 3 ( D } ) ; (iii) A 5 ( D { ) = max A 5 ( D) : A 3 ( D) = A 3 ( D ) and A 4 ( D) = A 4 ( D } ) and (iv) D is the unique set (up to isomorphism) satisfying (iii). It is obvious that, first of all, we should find 64-run design D with the maximum value of A 3. To obtain such designs, we use the following fact. Fact 3.3.. For a regular n-run design with 3 m n/ factors, the maximum A 3 is attained only by the designs constructed by repeating a design with m factors and n runs, where n = q with q satisfying q 1 m q 1. Clearly, A 3 = 0 for m = 1 and. By the above fact, we have the following five results: i Design D contains any one or two columns from H, if m = 1 or ; ii Design D is found from 4-run designs, if m = 3; iii Design D is found from 8-run designs, if 4 m 7; iv Design D is found from 16-run designs, if 8 m 15; v Design D is found from 3-run designs, if 16 m 31. 1

According to the above results and Rule 3.3.1, we obtain the corresponding unique design D of m factors for 8 m 31 from the complete catalogue for 16-run designs and 3-run designs. The 4-run design with 3 factors and 8-run designs with 5 m 7 factors are unique for each m. For m = 4, there are two nonisomorphic designs, and we choose the one with large A 3 ( D). The final results are summarized in Table 3.4. Tang and Wu (1996) also gave some recursive formulas, which can be used to determine the constants in (3.1)-(3.3). After some calculations, we obtain A 3 (D) = 1 [( ) ( ) m m + m m 3 A 4 (D) = 1 [ ( ) m 3 m 4 3 and A 5 (D) = 1 [( ) m + 1 5 4 4 1 ( ) m 4 3 m + 1 3 ] ( ) m (4 m) + 1 3 6 ( m 1) + 1 1 ( m A 3 ( D), (3.4) ( ) m + m m 3 ( ) m + 3 ( )] m + A 3 ( 3 D) + A 4 ( D), (3.5) ( ) m (3 m 7m + 9) + 1 ( )( ) ( ) m m m + 6 4 ) (3 m 4m + 13) + 14 ] m m (7m m 1) ( f 1 m)a 3 ( D) A 4 ( D) A 5 ( D). (3.6) Using (3.4)-(3.6), the A 3, A 4, A 5 values of minimum aberration designs with 33 m 63 are readily determined, and also contained in Table 3.4. Table 3.5 provides (A 3, A 4, A 5 ) s of minimum aberration designs and those of best designs from our approach. The results are very satisfying. About two-thirds of our best designs give the same (A 3, A 4, A 5 ) as the corresponding minimum aberration designs. Even though some cases give different results, the discrepancies are rather small. Among those cases with different results, there are 9 cases giving the identical A 3 values. Only cases have different A 3 values, but the differences are quite small.

Table 3.4: (A 3, A 4, A 5 ) of design D and that of the corresponding MA design D D D Number of Factors ( m) (A 3, A 4, A 5 ) Number of Factors (m) (A 3, A 4, A 5 ) 30 (140, 945, 4368) 33 (16, 140, 110) 9 (16, 819, 3640) 34 (3, 156, 40) 8 (113, 706, 301) 35 (48, 188, 3376) 7 (101, 605, 473) 36 (64, 1336, 4544) 6 (90, 515, 013) 37 (80, 1400, 5760) 5 (80, 435, 163) 38 (96, 1480, 7040) 4 (71, 365, 19) 39 (11, 1577, 840) 3 (63, 304, 1015) 40 (18, 1691, 9860) (56, 51, 784) 41 (144, 18, 1143) 1 (50, 05, 59) 4 (160, 1970, 13136) 0 (45, 175, 453) 43 (176, 145, 14960) 19 (41, 147, 337) 44 (19, 334, 16960) 18 (38, 16, 5) 45 (08, 543, 19136) 17 (36, 11, 196) 46 (4, 773, 1504) 16 (35, 105, 168) 47 (40, 305, 4080) 15 (35, 105, 168) 48 (56, 3300, 6880) 14 (8, 77, 11) 49 (80, 3556, 9904) 13 (, 55, 7) 50 (304, 3836, 33184) 1 (17, 38, 44) 51 (38, 4140, 36744) 11 (13, 5, 5) 5 (35, 4468, 40608) 10 (10, 15, 1) 53 (376, 480, 44801) 9 (8, 10, 4) 54 (400, 5199, 49344) 8 (7, 7, 0) 55 (44, 5603, 5464) 7 (7, 7, 0) 56 (448, 6034, 59584) 6 (4, 3, 0) 57 (476, 648, 6540) 5 (, 1, 0) 58 (504, 6958, 71344) 4 (1, 0, 0) 59 (53, 746, 7794) 3 (1, 0, 0) 60 (560, 7995, 85008) (0, 0, 0) 61 (590, 8555, 9568) 1 (0, 0, 0) 6 (60, 9145, 100688) 0 (0, 0, 0) 63 (651, 9765, 109368) 3

Table 3.5: (A 3, A 4, A 5 ) s of MA designs and those of the corresponding best designs from our approach for 33 m 63 Number of Factors MA designs Constructed designs Number of Factors MA designs Constructed designs (m) (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) (m) (A 3, A 4, A 5 ) (A 3, A 4, A 5 ) 33 (16, 140, 110) (16, 140, 110) 49 (80, 3556, 9904) (94, 3479, 9841) 34 (3, 156, 40) (3, 156, 40) 50 (304, 3836, 33184) (304, 3836, 33184) 35 (48, 188, 3376) (48, 188, 3376) 51 (38, 4140, 36744) (38, 4140, 36744) 36 (64, 1336, 4544) (64, 1337, 4544) 5 (35, 4468, 40608) (35, 4469, 40608) 37 (80, 1400, 5760) (80, 1401, 5760) 53 (376, 480, 44801) (376, 481, 44800) 38 (96, 1480, 7040) (96, 1483, 7040) 54 (400, 5199, 49344) (400, 5199, 49344) 39 (11, 1577, 840) (11, 1579, 8400) 55 (44, 5603, 5464) (44, 5603, 5464) 40 (18, 1691, 9860) (18, 1694, 9856) 56 (448, 6034, 59584) (448, 6034, 59584) 41 (144, 18, 1143) (144, 18, 1143) 57 (476, 648, 6540) (476, 648, 6540) 4 (160, 1970, 13136) (160, 1970, 13136) 58 (504, 6958, 71344) (504, 6958, 71344) 43 (176, 145, 14960) (176, 146, 14960) 59 (53, 746, 7794) (53, 746, 7794) 44 (19, 334, 16960) (19, 335, 16960) 60 (560, 7995, 85008) (560, 7995, 85008) 45 (08, 543, 19136) (10, 50, 1915) 61 (590, 8555, 9568) (590, 8555, 9568) 46 (4, 773, 1504) (4, 773, 1504) 6 (60, 9145, 100688) (60, 9145, 100688) 47 (40, 305, 4080) (40, 305, 4080) 63 (651, 9765, 109368) (651, 9765, 109368) 48 (56, 3300, 6880) (56, 3300, 6880) 4

Chapter 4 Concluding Remarks Starting with any two fractional factorials, either regular or nonregular, D 1 with m 1 factors and n 1 runs and D with m factors and n runs, we present a general approach to constructing a large design D with m = m 1 m factors and n = n 1 n runs. For any k with 1 k m 1 m, based on the type of D 1 we derive three equations that connect B k (D) to B s (D 1 ) s and B t (D ) s for s, t k. These results imply that the best design D from our approach can be constructed by choosing two minimum G -aberration designs D 1 and D. Regular 64-run designs of 7 m 63 factors are used to evaluate this approach. The findings are very promising - the A 3, A 4, A 5 values of the best designs from our approach are the same as or very close to those of the corresponding minimum aberration designs. In this project, the evaluation of our approach focuses on designs of 64 runs. One future work would be to evaluate our approach by looking at designs with 18 runs, as all minimum aberration designs of 18 runs are known, which can be used to compare with designs constructed from our approach. On the other hand, Deng and Tang (1999) defined another generalization of minimum aberration criterion, minimum G-aberration, to compare factorials for a given number of factors and run size. We may then use the general construction to obtain minimum G-aberration designs, which would be another interesting topic for the future work. 5

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