East Penn School District Secondary Curriculum

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East Penn School District Secondary Curriculum A Planned Course Statement for Applied Biology Course # Grades Department 400 9-10 Science Length of Period (mins): 40 mins Total Clock Hours: 140 Periods per Week: 7 Length of Course (years): 1 year Type of Offering: Elective Credit: 1.2 Adopted: June 2014 Developed by: Corinna Kramer-Hinks Rachel Kramer Tracy Dreher Kelly Musselman Deborah Barthold

Description of Course Course Title: Biology 1, Applied Description: This course is designed to acquaint the students who have limited math and science skills with the concepts of biology. The course content will focus on the interdependence of the living and non-living world. This course will include the topics of cells (structure, function, reproduction, and interactions with environment), biotechnology, and ecology. The unity and diversity of organisms and development of species will be studied within the context of classification, based on heredity and genetics. Goals: The students will be able to Describe interdependencies that exist between living things and the interactions that occur among them and their environment. Build an understanding of the basic characteristics shared by all organisms: cells, cell processes, energy relationships, and genetics. Describe how species change over long periods of time using the study of fundamental genetic principles Explain how biotechnology plays an important role in society. Improve their math and science skills through frequent application in the context of biology Appreciate the living world and their significant place in it. Requirements: No Prerequisites. Text: Biology: Pearson Foundations Edition by Miller and Levine. Pearson Publishing Company 2014 Copyright: Key to Levels of Achievement (Listed with each learning objective) Awareness (A) Learning (L) Understanding (U) Reinforcement (R) Students are introduced to concepts, forms, and patterns. Students are involved in a sequence of steps and practice activities which involved further development and allow evaluation of process. Students demonstrate ability to apply acquired concepts and skills to individual assignments and projects on an independent level. Students maintain and broaden understanding of concepts and skills to accomplish tasks at a greater level of sophistication.

Applied Biology Big Idea Eligible Content STD or EC code Grade Level Concepts (What students should know) Competencies (What students should be able to do) Suggested Assessments Suggested Learning Activities Duration Essential Questions/Content 1. Cell and Cell BASIC BIOLOGICAL PRINCIPLES Bio.A.1.1.1 Describe the characteristics of life shared by all prokaryotic and eukaryotic organisms. What is a living thing? What characteristics do all living things share? (ch 1) What are prokaryotes and eukaryotes? (ch 7) Define what an organism is. Identify the characteristics of life shared by all organisms. Compare/contrast prokaryotes and eukaryotes. (ch 7) 2. Cell and Cell BASIC BIOLOGICAL PRINCIPLES Bio.A.1.2.1 Compare and contrast cellular structures and their functions in prokaryotic and eukaryotic cells. How do all cellular structures, each with their unique functions, work as a collective living unit? Describe and identify the role and general structure of the cell nucleus, nuclear membrane, nucleolus, vacuoles, lysosomes, plasma membrane, cytoplasm, golgi apparatus, endoplasmic reticulum, mitochondria, chloroplast, cell wall, centrioles, cilia, flagella, pili, and cytoskeleton. Compare/contrast prokaryotic and eukaryotic cells. Compare/contrast plant and animal eukaryotic cells. Analogy 3. Cell and Cell BASIC BIOLOGICAL PRINCIPLES Bio.A.1.2.2 Describe and interpret relationships between structure and function at various levels of biological organization (i.e., organelles, cells, tissues, organs, organ systems, and multicellular organisms). What are the levels of biological organization? Construct and interpret the hierarchy of levels of biological organization from smallest to largest. Evaluate the levels of biological organization based upon structure and function.

4. Cells and Cell Bio.A.2.1.1 Describe the unique properties of water and how these properties support life on Earth (e.g., freezing point, high specific heat, adhesion, cohesion, and transpiration). How does the structure of water result in its unique properties and how it supports life on Earth? Define water as a solvent. Summarize how water s polarity affects its properties as a solvent. Identify and explain properties of water (i.e. adhesion, cohesion, high specific heat, transpiration, freezing point) Analyze how these properties of water relate to life processes and survival of organisms. 5. Cells and Cell Bio.A.2.2.1 Explain how carbon is uniquely suited to form biological macromolecules. How does carbon bond with other molecules to form the molecules of life? Describe how the atomic properties of carbon allow it to form the skeleton of organic molecules. 6. Cells and Cell Bio.A.2.2.2 Describe how biological macromolecules form from monomers. How are the processes of dehydration synthesis and hydrolysis essential in the building and breakdown of biological macromolecules? Define and explain the relationship between a monomer and a polymer. Define and identify the four major biological macromolecules of life. 7. Cells and Cell Bio.A.2.2.3 Compare and contrast the structure and function of carbohydrates, lipids, proteins, and nucleic acids in organisms. How are the four groups of macromolecules (i.e. carbohydrates, lipids, proteins, and nucleic acids) essential and supportive to life on Earth? Identify the sources from which carbohydrates, lipids, proteins, and nucleic acids can be found. Describe the general structure of each of the four groups of macromolecules. Compare and contrast the unique functions of carbohydrates, lipids, proteins, and nucleic acids in living things? 8. Cells and Cell BIO.A.2.3.1 Describe the role of an enzyme as a catalyst in regulating a specific biochemical reaction. How do enzymes carry out essential biochemical reactions in living things? Describe the specific roles enzymes play in living things. Explain how enzymes speed up specific biochemical reactions by lowering activation energy.

Analyze a graphical representation of the effects of enzymes activity on chemical reactions. 9. Cells and Cell BIO.A.2.3.2 Explain how factors such as ph, temperature, and concentration levels can affect enzyme function. What conditions affect enzyme activity in living things? Identify factors such as ph, temperature, and concentration levels and how they influence enzyme activity. 10. Cell and Cell BIOENERGETICS BIO.A.3.1.1 Describe the fundamental roles of plastids (e.g., chloroplasts) and mitochondria in energy transformations. What roles do plastids (e.g. chloroplasts) and mitochondria play in energy transformations in living things? Define photosynthesis and cellular respiration. Differentiate between the processes that occur in chloroplasts and mitochondria? Summarize the processes and identify the end product(s) of photosynthesis and cellular respiration as they occur in plants and animals. Explain the relationship between photosynthesis and cellular respiration in plants. 11.Cells and Cell BIO.A.3.2.1 Compare and contrast the basic transformation of energy during photosynthesis and cellular respiration. Where does the energy for all life come from? How do potential energy, kinetic energy, and thermal energy transform through the processes of photosynthesis and cellular respiration? What are the parts/stages of photosynthesis and cellular respiration? Describe the role of the sun with respect to energy in all living things. Differentiate between different types of energy (potential, kinetic, and thermal) and relate them to photosynthesis and cellular respiration. Describe the role of glucose in organisms. Define glycolysis, Krebs cycle, electron transport chain, light reaction and Calvin cycle. 12. Cells and Cell BIO.A.3.2.2 Describe the role of ATP in biochemical reactions. What is the importance of ATP in all living things? Describe the conversion of energy between glucose and ATP. Relate the structure of ATP to its function.

Differentiate between aerobic and anaerobic processes and net gain of ATP. 13. Cells and Cell HOMEOSTASIS AND TRANSPORT BIO.A.4.1.1 Describe how the structure of the plasma membrane allows it to function as a regulatory structure and/or protective barrier for a cell. What is the function of the cell membrane? (ch 7) Relate the structure of the plasma membrane to its function. Identify the parts of the plasma membrane including the polar heads, fatty acid tails, and proteins. Relate the chemistry of water to the structure of the cell membrane. 14. Cells and Cell HOMEOSTASIS AND TRANSPORT BIO.A.4.1.2 Compare and contrast the mechanisms that transport materials across the plasma membrane (i.e., passive transport -- diffusion, osmosis, facilitated diffusion; active transport -- pumps, endocytosis, exocytosis). What is passive transport? (ch 7) What is active transport? (ch 7) Relate the processes of diffusion and osmosis to cellular transport. Differentiate between how and where different types of substances pass through the plasma membrane.(phospholipids, protein channels, protein pumps and phagocytosis) Define hypertonic, hypotonic, and isotonic and the effect on cells. : Plasmolysis 15. Cells and Cell HOMEOSTASIS AND TRANSPORT BIO.A.4.1.3 Describe how membrane bound cellular organelles (e.g., endoplasmic reticulum, Golgi apparatus) facilitate the transport of materials within a cell. What organelles help make and transport proteins? (ch 7) Identify the role of ribosomes, ER, and Golgi apparatus in making proteins. Sequence the steps in making, modifying and transporting proteins. 16. Cells and Cell HOMEOSTASIS AND TRANSPORT BIO.A.4.2.1 Explain how organisms maintain homeostasis (e.g., thermoregulation, water regulation, oxygen regulation). How do individual cells maintain homeostasis? (ch 7) How do cells of multicellular organisms work together to maintain homeostasis? ( ch 7) Define homeostasis. Differentiate between how unicellular and multicellular organisms maintain homeostasis. Identify different examples of how organisms maintain homeostasis.

17. Continuity and CELL GROWTH & REPRODUCTION BIO.B.1.1.1 Describe the events that occur during the cell cycle: interphase, nuclear division (i.e., mitosis or meiosis), cytokinesis. Describe the significant events in Prophase, Metaphase, Anaphase and Telophase/ Cytokinesis (ch 9 iguana) Summarize the major events that occur during each phase of mitosis. Explain how cytokinesis differs in plant and animal cells 18. Continuity and CELL GROWTH & REPRODUCTION BIO.B.1.1.2 Compare and contrast the processes and outcomes of mitotic and meiotic nuclear divisions. What are the processes of mitosis and meiosis used for? Compare/contrast mitosis and meiosis. Relate haploid and diploid structures in organisms. Describe the main phases involved including chromosome number, # of cells at the beginning and end, names of the resulting cells, location, and functions. 19. Continuity and CELL GROWTH & REPRODUCTION BIO.B.1.2.1 Describe how the process of DNA replication results in the transmission and/or conservation of genetic information. What is the purpose of DNA replication in the cell? Identify the structures of DNA and how complementary base pairing occurs in DNA. Formulate the importance of DNA replication. Outline the steps of DNA replication and its result. Explain how the process of DNA Replication is semi-conservative in nature. 20. Continuity and CELL GROWTH & REPRODUCTION BIO.B.1.2.2 Explain the functional relationships among DNA, genes, alleles, and chromosomes and their roles in inheritance. How are genes and chromosomes inherited? Construct a flowchart summarizing the functional relationship between DNA, genes, and chromosomes as part of inheritance. Relate the importance of the precision of DNA replication to inheritance. 21.Continuity and GENETICS BIO.B.2.1.1 Describe and/or predict observed patterns of inheritance (i.e., dominant, recessive, codominance, incomplete dominance, sex-linked, polygenic, How are Mendelian and Non- Mendelian patterns of inheritance predicted? Define dominant, recessive, homozygous, heterozygous, allele, phenotype and genotype. Explain Mendel s Principles of Dominance, Independent Assortment, and Segregation.

and multiple alleles). Demonstrate how a Punnett Square is used to predict outcomes in crossing of two parents. Identify how alleles interact in intermediate inheritance. Describe inheritance patterns involving multiple alleles. Analyze how polygenic inheritance results in a wide range of phenotypes. Explain how the difference in the structures of the X and Y chromosomes result in different inheritance patterns in males and females. Describe how environmental conditions can affect phenotypic expression. 22. Continuity and GENETICS BIO.B.2.1.2 Describe processes that can alter composition or number of chromosomes (i.e., crossing-over, nondisjunction, duplication, translocation, deletion, insertion, and inversion). What are the effects of errors in meiosis? What processes affect the number of and composition of chromosomes? Explain the effects of crossing over and nondisjuction in Meiosis I and Meiosis II. Compare and contrast the different types of chromosomal damage such as duplication, deletion, insertion, inversion, and translocation and give examples of disorders in which this occurs. 23. Continuity and GENETICS BIO.B.2.2.1 Describe how the processes of transcription and translation are similar in all organisms. What is the central dogma of molecular biology? What are the steps involved in making a protein? Trace the information flow from DNA to protein including the processes of transcription and translation. List the three main types of RNA and describe what they do. Compare and contrast RNA and DNA. Explain the relevance of a triplet code. Discuss why the genetic code is universal. Define the following terms: o RNA polymerase o mrna codon

o exons o introns o anticodons o amino acids o polypeptide o transcription o translation Utilize an mrna codon chart to identify amino acids specified by codons to produce a polypeptide. 24. Continuity and GENETICS BIO.B.2.2.2 Describe the role of ribosomes, endoplasmic reticulum, Golgi apparatus, and the nucleus in the production of specific types of proteins. How are specific types of proteins produced in a cell? Trace the pathway of protein manufacture in a cell. Make an analogy about the role of ribosomes, endoplasmic reticulum, golgi apparatus in the production, processing, and assembling of proteins. 25. Continuity and GENETICS BIO.B.2.3.1 Describe how genetic mutations alter the DNA sequence and may or may not affect phenotype (e.g., silent, nonsense, frameshift). What are mutations? How does a mutation effect genes and affect an organism s phenotype? Compare and contrast the following DNA nucleotide changes (point mutations): o insertion o deletion o substitution Explain how insertion and deletions cause frame-shifts. Describe the difference between silent, nonsense, and missense mutations. Analyze how the redundancy of the codons affects proteins/phenotype. 26. Continuity and GENETICS BIO.B.2.4.1 Explain how genetic engineering has impacted the fields of medicine, forensics, and agriculture (e.g., selective breeding, gene splicing, cloning, genetically modified What is the impact of genetic engineering in real world applications? What techniques are used to study human DNA? Identify various procedures in recombinant technology. Define genome, restriction enzyme, plasmid, and genomics. Explain the procedure and rationale for gel electrophoresis and polymerase chain reaction.

organisms, gene therapy). Investigate current applications of genetic engineering in medicine, forensics, agriculture, and breeding. Analyze the social, political, and legal implications of genetic engineering. 27. Continuity and THEORY OF EVOLUTION BIO.B.3.1.1 Explain how natural selection can impact allele frequencies of a population. What is natural selection? Define the terms adaptation, natural selection, evolution, gene pool, allele frequencies, and population. Illustrate Darwin s main principles of natural selection and descent with modification as the mechanisms for evolution. Evaluate and apply aspects of natural selection (i.e. overpopulation, genetic variation, competition, and struggle for existence) to changes in allele frequencies in a population. 28. Continuity and THEORY OF EVOLUTION BIO.B.3.1.2 Describe the factors that can contribute to the development of new species (e.g., isolating mechanisms, genetic drift, founder effect, migration). How are new species formed? (Ch17) Define the biological species concept. Differentiate between the mechanisms of speciation including geographic and reproductive isolation, genetic drift, founder effect, and migration. Apply the mechanisms of speciation to examples of species which illustrate those mechanisms, and how the mechanisms can affect those population sizes. 29. Continuity and THEORY OF EVOLUTION BIO.3.1.3 Explain how genetic mutations may result in genotypic and phenotypic variations within a population. How do genetic mutations lead to genetic variation in terms of evolution? Define the terms genotype, phenotype, gene mutations, and chromosomal mutations. Discuss how genetic and chromosomal mutations result. Understand the impacts that mutations have on genes (genotypes), physical traits (phenotypes) and proteins within a population using examples.

30. Continuity and THEORY OF EVOLUTION BIO.3.2.1 Interpret evidence supporting the theory of evolution (i.e., fossil, anatomical, physiological, embryological, biochemical, and universal genetic code). What are the main pieces of scientific evidence that support Darwin s theory of evolution by natural selection? (Ch 16.4) Examine various scientific evidence supporting the theory of evolution including the fossil record, homologous and analogous structures, vestigial structures, embryological the origins, common ancestry, molecular evidence (comparative DNA and protein structure). Justify how the scientific evidences can support the theory of evolution. 31. Continuity and BIO.A.3.3.1 Distinguish among the scientific terms: hypothesis, inference, law, theory, principle, fact, and observation. How do the aspects of the scientific process make it successful? Define terms hypothesis, inference, law, theory, principle, fact, and observation as they relate to the scientific process. Distinguish between a scientific principle, theory, and law. Formulate hypotheses to scientific questions and apply the scientific process (i.e. inferences, observations, etc.) to reach conclusions. First semester 32. Continuity and BIO.4.1.1 Describe the levels of ecological organization (i.e., organism, population, community, ecosystem, biome, biosphere). What are the levels of ecological organization? List and describe the relationship between different levels of organization within the biosphere. 33. Continuity and BIO.B.4.1.2 Describe characteristic biotic and abiotic components of aquatic and terrestrial ecosystems. What is the difference between biotic and abiotic factors? Define and give examples of biotic and abiotic factors, herbivores, carnivores, omnivores, and detritivores. Describe how biotic and abiotic factors affect organisms living in a particular ecosystem. Identify photic and aphotic factors and zones in aquatic ecosystems.

34. Continuity and BIO.B.4.2.1 Describe how energy flows through an ecosystem (e.g., food chains, food webs, energy pyramids). How does energy flow through an ecosystem? What do ecological pyramids illustrate? Define producer, primary, secondary, and tertiary consumers, and decomposers. Explain how food chains and food webs are related. Compare and contrast the 3 types of ecological pyramids (energy, biomass, numbers) Describe how energy flows through trophic levels in an ecosystem. 35. Continuity and Bio.B.4.2.2 Describe biotic interactions in an ecosystem (e.g., competition, predation, symbiosis). How do organisms interact in an ecosystem? What is symbiosis? Define symbiosis, competition, predation, mutualism, commensalism, and parasitism. Identify, describe and give examples of the 3 types of symbiotic relationships. Explain competition exclusion. 36. Continuity and BIO.B.4.2.3 Describe how matter recycles through an ecosystem (i.e., water cycle, carbon cycle, oxygen cycle, nitrogen cycle). How does matter move through the biosphere? Compare and contrast the movement of energy and matter in ecosystems. Identify and explain the steps of the water cycle, nitrogen cycle, carbon and oxygen cycle. Explain specific biotic and abiotic processes needed to cycle chemicals in an ecosystem. 37. Continuity and BIO.B.4.2.4 Describe how ecosystems change in response to natural and human disturbances (e.g., climate changes, introduction of nonnative species, pollution, fires). How do human activities impact ecosystems? Compare primary and secondary succession? Compare and contrast the difference between primary and secondary succession? Explain how human activities can affect biodiversity. 38. Continuity and BIO. B.4.2.5 Describe the effects of limiting factors on population dynamics and potential species extinction What is the role of limiting factors in controlling population growth? What are density-dependent and density-independent limiting factors? Analyze a population dynamic graph comparing predator and prey populations. Compare and contrast exponential (J) and logistic (S) growth curves.

Materials and Resources: Explain the difference between density-independent and densitydependent limiting factors. Relate the role of limiting factors to carrying capacity.