Georgia Gwinnett College CHEM 2212 Organic Chemistry II Course Syllabus Summer 2008 Class Meetings: Instructor: Office: E-Mail: Phone Number: Wiki page: MTWR, 9-11am, A1640 (class); MTW, 1.15-4pm, A1290 (lab) Dr. Richard Pennington C232 (in the cubicle farms ) rpenning@ggc.usg.edu 678-407-5790 (office) http://wiki.ggc.usg.edu/mediawiki/index.php/user:rpenning Why Organic Chemistry? A scientific revolution is under way a revolution that will give us safer and more effective medicines, cure our genetic diseases, increase our life span, and improve our quality of life. The revolution is based in biotechnology and the manipulation of the approximately 30,000 genes in the human body, but it relies on organic chemistry as the enabling science. It is our fundamental chemical understanding of biological processes at the molecular level that has made the revolution possible and that continues to drive it. Anyone who wants to understand or be part of the remarkable advances now occurring in medicine and the biological sciences must first understand organic chemistry. John McMurray, your course text author. Course Description: Organic Chemistry II is the second semester of a two semester classroom and laboratory sequence. The course focus is the fundamental principles, nomenclature, reactions and their mechanisms, preparative techniques, and spectroscopic tools of organic chemistry. Specific emphasis is on topics that support the GGC Biology and GGC Cell Biology and Biotechnology Program Outcome Goals. In addition, topics are chosen to satisfy the general ACS guidelines for introductory organic chemistry. Course prerequisites: Students must pass both CHEM 2211 and CHEM2211L (Organic Chemistry I and Organic Chemistry I Lab) with a grade of C or better, or receive official transcript credit of C or better for the same. Course Outcome Goals for CHEM 2211/2211L and CHEM 2212/2212L Students who have successfully completed the organic chemistry sequence will: 1. Understand and apply principles of chemistry, math, and information technology to the study of the organic chemistry. 2. Understand the bonding, stereochemistry, and 3-dimensional arrangement of atoms in molecules, their resulting influence on molecular properties, and apply them to determine why and how molecules react. GGC - CHEM 2212 Organic Chemistry II 1
3. Understand and apply spectroscopy to provide evidence for the structure and reactions of molecules. 4. Understand and apply the four general kinds of organic reactions (addition, elimination, substitution, rearrangement) and two general mechanisms (polar, radical) of how organic reactions occur. 5. Understand and apply techniques to synthesize organic molecules. 6. Understand, describe, and apply the fundamental chemistry; to include nomenclature, reactions, preparative synthesis, and reaction mechanisms, of key organic functional groups: a. Alkanes b. Alkenes c. Alkynes d. Aromatic compounds, aromaticity, and in particular benzene. e. Alkyl Halides f. Compounds with sp 3 -hybridized oxygen and their sulfur analogs: i. Alcohols. ii. Phenols. iii. Thiols. iv. Ethers. v. Sulfides. g. Carbonyl compounds, to include a thorough understanding of: i. Nucleophilic addition reactions. ii. Nucleophilic acyl substitution reactions. iii. Carbonyl α-substitution reactions. iv. Carbonyl condensation reactions. h. Amines 7. Understand and apply concepts of organic chemistry to the structures, functions, reactions, mechanisms, and synthesis of biomolecules to include: a. Amino Acids, Peptides, and Proteins. b. Carbohydrates. c. Lipids. d. Nucleic Acids. 8. Effectively and clearly communicate scientific information in written and oral form. 9. Use library and Internet resources to gather, organize, and understand scientific information. 10. Collect, present, and analyze scientific data gathered through experiment. 11. Understand and apply standard microscale laboratory equipment and techniques. 12. Understand and apply fundamental organic chemistry characterization techniques. 13. Understand and apply spectroscopic techniques and analysis: Infrared, Nuclear Magnetic Resonance, and Mass Spectrometry. 14. Perform a series of experiments, analyze data, and present results for a series of organic chemistry techniques and reactions. 15. Conduct organic qualitative analysis. GGC - CHEM 2212 Organic Chemistry II 2
Required Text and Supplies Organic Chemistry: A Biological Approach, John McMurry (2007). Study Guide and Solutions Manual for McMurray s Organic Chemistry: A Biological Approach, Susan McMurry (2007). Organic Chemistry Molecular Model Kit. al Organic Chemistry: A Miniscale and Microscale Approach, Gilbert and Martin (2005). Lab notebook comprised of carbonless duplicate pages. Safety goggles/glasses. Grading Policy: Quizzes and exams are designed to gauge student understanding of lesson/laboratory objectives and course outcome goals. A: 90.0 % and above B: 80.0 89.9 % C: 70.0 79.9% D: 60.0 69.9 % F: Less than 60.0 % Grading Basis: 1. Classroom course (CHEM 2212). The testing plan for the lecture course is summarized in the table below. The instructor grade of 50 points is determined by the instructor (class attendance and participation, instructor pop quizzes, special assignments, etc). Chapter quizzes are 20-30 minute quizzes focused on one or two chapters. The final exam is comprehensive. Graded events are a combination of definition, multiple choice, matching, short answer, sketches, diagrams, reactions, mechanisms, synthesis, and long answer. Complexity ranges from simple recitation of key word definitions to synthesis of information from multiple lessons/chapters to creatively solve novel problems. Class Graded Events Per semester Number Points Total Points Instructor 1 50 50 Chapter Quizzes 10 50 450* Final Exam 1 250 200 Total Points 700 * 450 points for the quiz total, as the lowest quiz score may be dropped. 2. Laboratory course (CHEM 2212L). Laboratory course (CHEM 2212L). Students will complete 6 graded experiments and 1 open book/notes synthesis exam. Each experiment is 2 lab periods for a total of 6 hours. Each experiment begins with an in class quiz worth 10 points. Students will submit an individual, written report for each experiment that is worth 40 points. There is no separate final exam for the lab. GGC - CHEM 2212 Organic Chemistry II 3
Lab Graded Events Per semester Number Points Total Points Quizzes 6 10 60 Reports 6 40 240 Synthesis Exam 1 100 100 Total Points 400 Cheating is expressly forbidden during exams. A student caught cheating will be given a zero for the work and the student s advisor and the Academic Dean will be notified. The Instructor and the Academic Dean will also deal with any other forms of academic dishonesty. The student will have the opportunity to evaluate the instructor and the course at the end of the semester through the use of a confidential rating form. However, during the semester, students are encouraged to communicate directly with the instructor concerning any aspect of the course. Attendance and Make-up Policies. You are expected to attend every class and lab. Failure to attend class and lab will affect your grade. Special arrangements to take a regular exam or laboratory period at other than the scheduled time must be made in advance, in writing. Such arrangements are available only at the instructor s discretion and only under extreme circumstances. IF an emergency arises and you miss an exam or lab, you MUST notify your instructor on the same DAY as the exam. Notification by email, text or phone message is acceptable. At the instructor s discretion, make-up work may have a different format or different content from the regular assignment. Make-up work should be completed within two days of the original date. Work missed to unexcused absences will be given a grade of zero. Students who never attend a class during the first two weeks of the term will be reported for non-attendance. Students who do not drop a class during the schedule adjustment period and are reported for non-attendance will be automatically dropped from that course General Comments The most important thing you can do to improve your performance and grade in this course is to keep up with the assigned reading and practice problems. In general: Read the textbook assignment before the lecture on that material. Attend lectures and take clear notes. After lecture, re-read the appropriate textbook pages and update your notes. Work the assigned problems promptly as the material is covered. Seek help if you do not understand the material or are unable to work a problem. Study for the exams by going over the lecture notes, reworking the problem assignments, and using the textbook as a guide where needed. GGC - CHEM 2212 Organic Chemistry II 4
CHEM 2212/L tentative schedule: Date Lesson CHEM 2212 Quizzes CHEM 22112 Lab Prelabs Lab Reports 1 23-24- 25-26- 1 Chapter 13 2 Chapter 13 Quiz # 1 3 Chapter 14 4 Chapter 14 Quiz # 2 H H Prelab Quiz Expt. H Lab H Report 2 30-1- 2-3- 5 Chapter 15 6 Chapter 15 Quiz # 3 7 Chapter 16 8 Chapter 16 Quiz # 4 I I J Expt. I Expt. J Lab I Report 3 7-8- 9-10- 9 Chapter 17 10 Chapter 17 Quiz # 5 11 Chapter 18 12 Chapter 18 Quiz # 6 J K K Expt. K Lab J Report Lab K Report 4 14-15- 16-17- 13 Chapter 18 14 Chapter 19 Quiz # 7 15 Chapter 19 16 Chapter 21 Quiz # 8 L L Synthesis Exam Expt. L Lab L Report 5 21-22- 23-24- 17 Chapter 21 18 Chapter 23 Quiz # 9 19 Chapter 23 20 Chapter 24 Quiz # 10 N N Expt. N Lab N Report Due 6 28-29- 21 Chapter 24 Final Review GGC - CHEM 2212 Organic Chemistry II 5