Jeffrey L. Katz Colby College Tel: (207) 859-5754 5754 Mayflower Hill Fax: (207) 859-5760 Waterville, ME 04901 Education Harvard University Ph.D. in Organic Chemistry May 2002 M.A. in Organic Chemistry June 1998 University of Pennsylvania B.A. in Chemistry, Magna Cum Laude June 1995 Experience Colby College Assistant Professor 2002 to 2008 Associate Professor 2008 to present Harvard University Graduate Student 1995 to 2002 Research and Teaching Assistant 1995 to 2002 University of Pennsylvania Undergraduate Student 1991 to 1995 Research Assistant 1994 to 1995 Teaching Colby College Chemistry 141 General Chemistry I (with laboratory) Chemistry 241 Organic Chemistry I (with laboratory) Chemistry 242 Organic Chemistry II (with laboratory) Chemistry 432 Advanced Organic Chemistry Chemistry 483/484 Honors in Research in Chemistry Chemistry 491/492 Independent Study Harvard University Chemistry 17 Principles of Organic Chemistry Chemistry 135 Experimental Synthetic Chemistry Chemistry 206 Organic Reaction Mechanisms
Student Researchers In The Katz Laboratory Eric Rosenthal 03 Katie Sigalow 05 Amy Campfield 05 Kevin Selby 05 Michael Feldman 05 Cary Fridrich 05 Bram Geller 06 Colby Burns 06 Kristopher King 07 Christian Crannell 08 Douglas Rooke 08 Michael Abers 10 Durann VanGorder 08 Joseph Meyer ( 09) Rebecca Thorburn ( 09) Whitney Miller ( 09) Stephen Carlin ( 09) Sarah King ( 10) Kwadwo Opoku-Nsiah ( 11) Mengfei Zhnag ( 11) Solomon Gisemba ( 11) Publications (Colby Students in Bold) Oxacalixarenes and Oxacyclophanes Containing 1,8-Naphthyridines: A New Class of Molecular Tweezers With Concave-Surface Functionality Katz, J. L.; Geller, B. J.; Foster, P. D., Chem. Commun. 2007, 1026-1028. Synthesis of Oxacalixarenes Incorporating Nitrogen Heterocycles: Evidence for Thermodynamic Control Katz, J. L.; Geller, B. J.; Conry, R. R., Org. Lett. 2006, 8, 2755-2758. "A Single-Step Synthesis of D 3h - Symmetric Bicyclooxacalixarenes" Katz, J. L.; Selby, K. J.; Conry, R. R. Org. Lett. 2005, 7, 3505-3507. "Synthesis of Functionalized Oxacalix[4]arenes" Katz, J. L.; Feldman, M. B.; Conry, R. R. Org. Lett. 2005, 7, 91-94. DNA Interstrand Cross-Linking by a Mycotoxic Diepoxide. Millard, J. T.; Katz, J. L.; Goda, J.; Frederick, E. D.; Pierce, S. E.; Speed, T. J.; Thamattoor, D. M. Biochimie, 2004, 86, 419-423. Prior to Colby: "Total Synthesis of Teicoplanin Aglycon." Evans D. A.; Katz, J. L.; Peterson, G. S.; Hintermann T. J. Am. Chem. Soc. 2001, 123, 12411-12413. "Nonconventional Stereochemical Issues in the Design of the Synthesis of the Vancomycin Antibiotics. Challenges Imposed by Axial and Non-planar Chiral Elements in the Heptapeptide Aglycons." Evans D. A.; Dinsmore, C. J.; Watson, P. S.; Wood, M. R.; Richardson, T. I.; Trotter, B. W.; Katz, J. L. Angew. Chem. Int. Engl. 1998, 37, 2704-2708. "Total Synthesis of Vancomycin and Eremomycin Aglycons." Evans, D. A.; Wood, M. R.; Trotter, B. W.; Richardson, T. I.; Barrow, J. C.; Katz, J. L. Angew. Chem. Int. Engl. 1998, 37, 2700-2704. "Synthesis of Diaryl Ethers through the Copper-Promoted Arylation of Phenols with Arylboronic Acids. An Expedient Synthesis of Thyroxine." Evans, D. A.; Katz, J. L.; West, R. T. Tetrahedron Lett. 1998, 39, 2937-2940. Mild nitrosation and hydrolysis of polyfunctional amides Evans, D. A.; Carter, P. H.; Dinsmore, C. J.; Barrow, J. C.; Katz, J. L.; Kung, D. W. Tetrahedron Lett. 1997, 38, 4535-4538.
Presentations Jeffrey L. Katz, W. Christian Crannell, Sarah B. King, Durann VanGorder Kinetic and Thermodynamic Fine-Tuning for the Selective Synthesis of Oxacalix[n]arenes, 32 nd Reaction Mechanisms Conference, June 2008. Jeffrey L. Katz. Making Big Rings: The Ins and Outs of Oxacalixarene Synthesis, TIM Consortium Meeting, June 2008. Jeffrey L. Katz. Molecular Design Through Nucleophilic Aromatic Substitution: Oxacalixarene-Based Molecular Toolbox, Georgetown University, January 2008. Playing with an Jeffrey L. Katz. Molecular Design Through Nucleophilic Aromatic Substitution: Playing with an Oxacalixarene-Based Molecular Toolbox, University of North Carolina, Charlotte, January 2008. Jeffrey L. Katz, Bram J. Geller, W. Christian Crannell, Douglas A. Rooke, and Michael S. Abers Oxacalixarene-Based Molecular Triangles, Squares, And Tweezers, Invited Lecturer, International Conference on Calixarene Chemistry, August 2007 Jeffrey L. Katz, Bram J. Geller, W. Christian Crannell, Douglas A. Rooke, and Michael S. Abers Oxacalixarene-Based Molecular Triangles, Squares, And Tweezers, National Organic Symposium, June 2007. Jeffrey L. Katz, Making Very Small Things: Playing with an Oxacalixarene-Based Molecular Toolbox, TIM Consortium Meeting, June 2007. Jeffrey L. Katz, Still Making Very Small Things: Playing with an Oxacalixarene-Based Molecular Toolbox, Colby College, February 2007. Jeffrey L. Katz. Molecular Design Through Nucleophilic Aromatic Substitution: Playing with an Oxacalixarene-Based Molecular Toolbox, Brown University, January 2007. Jeffrey L. Katz, Bram J. Gellar, Rebecca R. Conry. Heteroaromatic Oxacalixarene-Based Molecular Triangles, Squares, And Tweezers, Gordon Research Conference: Heterocyclic Compounds, July 2006. Jeffrey L. Katz. Nucleophilic Substitution for the Synthesis of Oxygen-Bridged Aromatic Arrays: An Oxacalixarene-Based Molecular Toolbox, University of Washington, April 2006. Jeffrey L. Katz. Oxacalixarenes and More: Nucleophilic Substitution for the Synthesis of Oxygen- Bridged Aromatic Arrays, University of Missouri, Nov 2005. Jeffrey L. Katz. Oxacalixarenes and More: Nucleophilic Substitution for the Synthesis of Oxygen- Bridged Aromatic Arrays, Procter & Gamble Lectureship, Colorado State University, Nov 2005. Jeffrey L. Katz, Michael B. Feldman, Kevin J. Selby, Cary G. Fridrich, Rebecca R. Conry. A single step to oxacalix[4]arenes, oxacalix[2]arene[2]pyridines, and bicyclooxacalix[4]arenes, Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005. Jeffrey L. Katz, Michael B. Feldman, Kevin J. Selby, Cary G. Fridrich, Rebecca R. Conry. Nucleophilic Aromatic Substitution for the Synthesis of Macrocyclic Oxygen-Bridged Aromatic Arrays, Gordon Research Conference: Organic Reactions and Processes, Aug 2005.
Jeffrey L. Katz, Michael B. Feldman, Kevin J. Selby, Cary G. Fridrich, Rebecca R. Conry. Synthesis of Oxacalixarenes and Bicyclooxacalixarenes by Nucleophilic Aromatic Substitution, Gordon Research Conference: Chemistry of Supramolecules and Assemblies, June 2005. Jeffrey L. Katz, Making Very Small Things: Building Nanoscale Architecture Through Oxacalixarene- Based Molecular Design, Colby College, March 2005. Student Poster Presentations Douglas A. Rooke, Jeffrey L. Katz, Mike S. Abers Synthesis of Caged, Para Linked, and Tweezer Oxacalixarenes, National Organic Symposium, June 2007. Douglas A. Rooke, Jeffrey L. Katz, Synthesis of Caged and Para Linked Oxacalixarenes, Colby Undergraduate Research Symposium, Colby College, May 2007. Christian Crannell, Jeffrey L. Katz, Selective Synthesis of Oxacalix[6]arenes and Mixed Oxacalix[4]arenes Colby Undergraduate Research Symposium, Colby College, May 2007. Kevin J. Selby, Jeffrey L. Katz, Synthesis and Characterization of Pyridine-based Bicyclooxacalixarenes, Colby Undergraduate Research Symposium, Colby College, April 2005. Michael B. Feldman, Jeffrey L. Katz, Synthesis and Characterization of Oxygen-Bridged Multi- Oxacalix[4]arenes Colby Undergraduate Research Symposium, Colby College, April 2005. Funding A Dispersed REU Site in Theoretically Interesting Molecules, 2007-2008, NSF-CHE-0552292, $260,898 total funding, Colby s allocation is approximately $25,000. CAREER: Molecular design through oxacalixarenes: synthetic methods, molecular receptors, and chemical sensors", March 2007-Feb 2012, National Science Foundation, NSF-0640729, $402,600. Exploiting The Oxacalixarene Scaffold: Structural Diversity, Macrobicyclic Hosts, Multicalixarenes, and Molecular Tweezers, Sept 2006-Aug 2009, Petroleum Research Fund #45440-B1, $50,000 Heteroatom-Bridged Aromatic Macrocycles: Development Of An Oxacalixarene-Based Molecular Toolbox, June 2006-May 2008, Cottrell College Science Award CC6665, Research Corporation, $42,684 Synthesis of Azacalixarenes, Oxocalixarenes, and Dicalixarene Cages, June 2004-May 2006, Cottrell College Science Award CC6148, Research Corporation, $39,684 MRI: Acquisition of a Preparative HPLC system for Undergraduate Research Training in Chemistry and Biology (co-pi), NSF, 2004-2006, $128,720 Colby College Division of Natural Sciences Grants, 2003-2004, $3,000; 2004-2005, $3,000; 2005-2006, $3,000; 2006-2007, $3000, 2008-2009, $3000 Professional Service
Session Chair at the American Chemical Society national meeting, Heterocycles and Aromatics section, Sept 2005 Outside Peer-Reviewer for: 19 manuscripts in The Journal of the American Chemical Society, Organic Letters, Tetrahedron Letters, and The Journal of Organic Chemistry Outside Peer-Reviewer for: 11 grants from The National Science Foundation, The Petroleum Research Fun, and Research Corporation Attended Meetings and Conferences 236th ACS National Meeting, Philadelphia, PA, United States, Aug. 27-Aug. 21, 2008. 32 nd Research Mechanisms Conference, June 25-29, 2008, UNC-Chapel Hill TIM Consortium Meeting, June 24 th 2008, UNC-Chapel Hill International Conference on Calixarene Chemistry, August 2007, University of Maryland National Organic Symposium, June 2007, Duke University TIM Consortium Meeting, June 2007, Raleigh-Durham, NC Gordon Research Conference: Heterocyclic Compounds, July 2006, Salve Regina University 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005. Gordon Research Conference: Organic Reactions and Processes, Aug 2005, Bryant University Gordon Research Conference: Chemistry of Supramolecules and Assemblies, June 2005, Colby College