ithemba LABS shaping the future with SAIF : South African Isotope Facility Faiçal Azaiez

ithemba LABS shaping the future with SAIF : South African Isotope Facility Faiçal Azaiez

ithemba LABS (Laboratory for Accelerator Based Science) ithemba LABS provides research platforms for pure and applied research, development and training in Accelerator Based Sciences Nuclear Physics Training and Education Science Awareness & Communication

Two Campuses 1. ithemba LABS (Faure), Cape Town (HQ) 2. Themba LABS (Gauteng)

ithemba LABS Strategic ObjecCves 4

ithemba LABS Key StaCsCcs! Annual Budget ~20M$ ( ~15M$ Core Grant)! Isotope ProducCon Revenue ~5M$! Staff ~ 300! ~150 publicacons per year! Students Supervised ~ 90/year

University Collaboration University of the Western Cape Nelson Mandela Metropolitan University of Cape Town University of Limpopo University of Stellenbosch University of Venda Cape Peninsula University of Science and Technology University of Johannesburg University of the Witwatersrand University of Pretoria North West University Fort Hare University University of Kwazulu Natal University of Zululand North West University

Longer term project : CARN African CollaboraCons Country/University 1. Mozambique (Eduardo Mondlane University) 2. Zambia (University of Zambia) 3. Botswana (Univ. Botswana, + BIUST) 4. Nigeria (University of Ile-Ife + CERD) 5. Sudan (Univ. Sudan Science & Tech) 6.Cameroon (University of Yaoande) 7. Ghana ( University of Ghana) 8. Ethiopia: (University of Addis Ababa 9. Senegal (Cheik Anta Diop University) 10. Algeria (COMENA) 11. Senegal (Cheik Anta Diop University) 12. Burkina Faso 13. Egypt UNAL CHILE African Institutions Collaborating with ithemba LABS

ithemba LABS OrganizaConal Structure PAC s & Users commiwees Advisory commiwee (sciencfic, technical) Radioprotection service DIRECTOR Deputy director 1: Research Health and safety Radio-protecfon NRF Finance-business- Infrastructure /logistics HR transformation African &International office Scien-tech com & outreach Deputy director 2: Universifes&training Employment equity lnternafonal & outreach NECSA Accelerators Engineering Instrumentation Radia-biology dept Mater Scien dept SAIF- project Gauteng dept Nucl Phys dept Radio-Isotope dept 8

ithemba LABS (Gauteng) 6 MV Tandem (Gauteng): Previously Schonland Research Centre of the University of the WitwatersrandExtensively refurbished and FiJed with a Ion Source for Accelerator Mass Spectrometry Accelerator Mass Spectrometry (AMS) Facility Recently unveiled at ithemba LABS (Gauteng) 14 C dacng: 60 000 years Other isotopes ( 10 Be, 36 Cl, 26 Al): 1 10 My

ithemba LABS Gauteng Heavy Ion AMS Ion Source AMS Beam Line Microprobe Beam Line Nuclear Physics Beam Line

Accelerators complex at ithemba LABS (FAURE) K8 Injector cyclotron 1 K200 Separated sector cyclotron cyclotron K11 Cyclotron 6MV Van de Graaff 6MV Tandem K8 Injector cyclotron 2 11

ECR sources at ithemba LABS

Beams delivered at ithemba LABS 66 MeV Proton Beams (SPC1) Beam current on target: 250 µa Transmission efficiency: 99.8%

Ion source for polarized protons (Electrostatic Ionizer)

Polarized ion source Separated-Sector Cyclotron Facility SSC Target vaults Spectrometer SPC2 ECR ion source SPC1 electronics electronics Radioisotope production Proton therapy Neutron therapy 0 10 20 m

Isotope department Production of radionuclides and radiopharmaceuticals for both the national (25 clients) and international (60 clients) market: 123 I, 67 Ga 3 Bombardment StaCons (66 MeV proton beams) ( 18 F target stacon ) 11 MeV Cyclotron for 18 F

ithemba LABS Radionuclide Distribution Network Africa 3 Australia 2 Asia 19 Canada 2 Europe 31 USA 12

cgmp Radiopharmaceuticals Supply over 25 local Nuclear Medicine Hospitals and Private Clinics

Long-Lived Radionuclides Supply over 60 clients worldwide

Patient Impact SSC and 11 MeV Cyclotron >1300 shipments per annum that impacts on >100 000 patients worldwide

ParCcle Therapy 200 MeV proton beam Fixed horizontal line Neutrons from 66 MeV protons on Be Isocentric treatment facility

In Operafon 40 Under Construcfon 20

Radiobiology Research and Development Activities Molecular Radiation Biology radiosensitivity breast and cervix cancer Cellular Radiation Biology radiosensitivity and HIV status Automated Radiation Bio-dosimetry methods Auger electron DNA damage Dose-volume effects protons and neutrons NTeMBI projects in consortium with other Institutions Early detection of cancer Hypoxic cell markers in cancer Dendrimers (large molecules) for detection and treatment cancer with radioactive isotopes Malaria prevention chemical dosimetry

Nuclear Physics FaciliCes FaciliCes AFRODITE Gamma Array Spetrometer K600 MagneCc Spectrometer Fast neutron facility ScaWering Chamber AFRODITE K600 MagneMc Spectrometer: An instrument for high energy resolumon nuclear physics spectroscopy

Fast neutron facility Beam dump magnet E p <= 200 MeV Li or Be Producfon target - neutron dosimetry - radiobiological effeccveness of fast neutrons - detector development - Neutron induced cross seccons

Materials Research Department

Replacement of the 50 years old Van de Graaff Accelerator ExisCng Van de Graaff Replace 3 MV Tandem

IBA Techniques with 6.0 MV Van de Graff µnra 6.0 MV VDG 3.0 MV Tandetron µpixe, µrbs Incident Ion PIGE In situ ERDA TransmiWed ion In-situ Channeling Light ToF HI-ERDA 10/12/16 Auger e - In situ RBS 28

PreparaCon for the 3 MV tandetron Strategic Breakaway 25-26 April 2016 JL Conradie

LRP of ithemba started on May 2016 and will be finalized before the end of the year Some ideas though on where we are intending to bring ithemba

The Future at ithemba is SAIF the South African Isotope Facilities (isotopes for science and society)

ithemba-saif towards ithemba-carn - ACE-BI: African Center for Exofc Beams and Isotopes - South African Centre of Excellence for Sub-Atomic Physics (ithemba-ce) (with strong links to CERN, FAIR and major facilifes in US, EU, ASIA. but also NuPECC, NSAC and ANPhA) - South African Insftute of Nuclear Technology and Science (SAINTS) (Gateway to Nuclear technology for Africa) - Ulfmate Goal is to work on the concept of CARN for ithemba

Vision for 2019: ACE-BI ACE-ISOTOPES ACE-BEAMS

Lot of challenges some of them are very high but this we can take.. The most serious difficulty : Shortage of funds for research..( economical crisis) The strategy within DST has changed since I have agreed to join ithemba (more than a year ago): Strong lobbying of the internafonal astronomy community.. Made it that SKA became the highest priority and thus takes all MONEY!!

We need a strong lobbying and support from the internafonal Nuclear Physics community So far (and since yesterday s C12 meefng) this has been disappoinfng and I am quesfoning the place of ithemba/sa and even larger the other (7) African countries in IUPAP