Profile of DR. SHOBHA RANI TENKAYALA Head & Assistant Professor, Dept. of Organic Chemistry, Dravidian University, Kuppam, Chittoor (DT), A.P., INDIA Mobile: +91-9494435886 E-mail: sobha.kaushu@gmail.com kaushureddy@gmail.com KEY-WORD SUMMARY Ph.D. Materials Chemistry, Synthesis, Characterization and Applications of Water Glass based Silica Aerogels and their Hybrids. Silica aerogels for Insulation, Aerogels for Drug delivery Matrices. Synthesis of Indole, Quinoline and Pyrimidine derivatives, Nano-hybrids, Micro structure and Textural Properties. HIGHLIGHTS Seven Years Experience in Synthetic Organic Chemistry Development of Organic molecules for Industrial applications, Development of Silica based Nano particles, Catalysts, Emulsions and Nano materials, Control Release Studies of Drugs and Pharmaceuticals, Polymer Membranes for Separation Processes, Synthesis of Pyrimidine derivatives and its Drug delivery Applications, Development of New Polymer Composites and CNT Nano Composites. Adaptability to any Kind of Work, Excellent Problem Solving Abilities and Good Communication Skills. Strong Knowledge in General Office Software s, Windows 98/2003/2007/XP, Excel, Ms-Office, DOS, Power point presentations, Paint, Photoshop, Origin, Adobe s Photo Deluxe and Chemistry Software s, Chem Draw, Chem sketch, Chem window etc. Well versed with Office Automation & Internet Applications.
EDUCATION QUALIFICATION 2009 Ph. D. in Chemistry (71.4%). Sri Krishnadevaraya University, Anantapur, A.P, INDIA. Title of the Thesis: Optimization of the Synthesis, Characterization and Applications of Silica Aerogel Powders and its Hybrids. 2006 M. Sc. in Chemistry Sri Krishnadevaraya University, Anantapur, India (72.07%). 2005 Bachelor of Education (70.07%) [B.ED.] Sri Krishnadevaraya University, Anantapur, AP, INDIA 2003 B. Sc. with Chemistry & Biochemistry as major subjects Sri Krishnadevaraya University, Anantapur, India (72. 54%). RESEARCH EXPERIENCE Visiting Researcher, from April 2008 to March 2009, under the Optimization of the Synthesis of Nano Silica Aerogel Powders for Industrial Applications Project at Division of Advanced Chemical Engineering, Nano Technology, Pukyong National University, and Busan, South Korea. Research Fellow, from January 2007 to March 2007, under Study of Controlled Release of Drugs and Pharmaceuticals from in-situ Polymerizable Hydrogels. Project at Organic Coatings and Polymers Division, Indian Institute of Chemical Technology, Hyderabad 500 007 Andhra Pradesh, India. TEACHING EXPERIENCE Asst. Prof. of Chemistry, S.K.D. Engineering College, (JNTUA) N.H-7, Gooty, Anantapur, Lecturer in Chemistry at CMI Degree College, S. K. U. Anantapur, during 2006-2007. Assisted in Teaching theory and conducting experiments to M. Sc. (Chemistry) first and Final Year Students in the Department of Chemistry, Sri Krishnadevaraya University, Anantapur, India for the academic year 2007-08.
ADMINISTRATIVE EXPERIENCE Worked as Head of the department of Chemistry at Sri Krishanadevaraya Eng. College, J.N.T.University, N.H-7, Gooty, Anantapur, and Andhra Pradesh, India. Worked as Coordinator for all Notice Board activities at Sri Krishanadevaraya Eng. College, J.N.T.University, N.H-7, Gooty, Anantapur, and Andhra Pradesh, India. Worked as a Member in the Placement Committee at Sri Krishanadevaraya Eng. College, J.N.T.University, N.H-7, Gooty, Anantapur, and Andhra Pradesh, India. Worked as a Member in the Antiragging Committee at Sri Krishanadevaraya Eng. College, J.N.T.University, N.H-7, Gooty, Anantapur, and Andhra Pradesh, India. Working as Coordinator for Physics & Chemistry Subjects in Distance Mode, Dravidian University, Kuppam. Working as Member in the Board of Studies, Dept. of Chemistry, Dravidian University, Kuppam. Working as Member in Academic Research Committee, Dravidian University, Kuppam. Worked as Member in University Different Administrative Committees, D. University. RESEARCH GUIDANCE Research supervisor (Sathyabama University, TNT for Part- Time Research programme). Research supervisor (Bharthiar University, TNT for Part- Time Research programme). Research supervisor (Karpagam University, TNT for Part- Time Research programme). Present 4 Members are Doing Ph.D Under My guidance PROJECTS HANDLING Synthesis, and Characteri zation of 2-(phenyl amino) Pyrimidine Derivatives. Funded by UGC Innovative Research Programme of XII plan, Dravidian University, Kuppam. Ref. No. DU/UGC/Innovative Research Activities/2013 dated 5. 03. 2014. EXPERIMENTAL / ANALYTICAL SKILLS DSC, TGA, FT-IR, TG-DTA, UV Spectrophotometer, HPLC, GPC, Scanning Electron Microscopy, and X-Ray Diffractometer.
Universal Testing Machine, Flexural Tester, Izode Impact Tester, Rockwell Hardness Tester. Ultrasonic Interferometer, Refractometer. BET (Brunauer, Emmett and Teller) and BJH (Barrett-Joyner-Halenda) methods. Ultracentrifuge Automated Dissolution Tester. Analytical instruments- potentiometer, conductivity and ph- meter. Membership I am the Fellow in the Journal of Indian Chemical Society, Kolkata, INDIA. (F/7076). I am the Fellow in the International Congress of Chemistry & Pharmacy, Anantapur, and Andhra Pradesh, INDIA. (FICCP/206). JOURNAL REFEREE/REVIEWER 1. Journal of Applied Polymer Science (http://www.wileyinterscience.com/science/journal/08051616). 2. International Journal of Physical Sciences (http://www.academicjournals.org/ijps/ijps-09-138). 3. Journal of Composite Materials (http://mc.manuscriptcentral.com/jcm/jcm-10-0048). 4. Journal of Medicinal Plants Research (http://www.academic journals.org/jmpr/jmpr-10-071). 5. Physical Chemistry Chemical Physics (http://mc. manuscriptcentral.com/pccp CP-ART-04-2010-000313). 6. African Journal of Environmental Science and Technology. 7. Journal of Bio Resources. FELLOWSHIPS AND GRANTS Visiting Researcher Fellowship by Korean Research Foundation South Korea. PUBLICATIONS 1. T. Shobha Rani, M.C.S. Subha, Yong-Ha Kim *, Venkata Reddy G., Young - Soo Ahn b, Water-Glass based Silica Aerogel Powder With and Without Squeezing of Hydrogels. Journal of Applied Polymer Science, Vol. 115, No. 3, 1675-1679, (2010). 2. T. Shobha Rani, M.C.S. Subha, Venkata Reddy G a., Yong-Ha Kim a*, Young-Soo Ahn b, Synthesis and Characterization of Poly (vinyl alcohol)/water glass (SiO 2 ) Nano - Hybrids
via Sol -Gel Process Journal of Applied Polymer Science, Vol. 117, No. 6, 3533-3538, (2010). 3. T. Shobha Rani, M.C.S. Subha, Venkata Reddy G a., Yong-Ha Kim a*, Young- Soo Ahn b, Optimization of the Synthesis of Silica Aerogel Powder using the Fluidized Bed Drying Bull. Che. Sci., Vol. VII, Issue I, p.p. 49-59, ISSN NO. 0973-8134, (2009). 4. T. Shobha Rani, Yong-Ha Kim a Venkata Reddy G a C. Venkata Prasad, B. Yerri Swamy, B. Mallikarjuna, Effects of Fluidized Bed Drying Parameters on the Physical Properties of Water glass based Silica Aerogel Powders, Bull. Phy. Sci. Vol. VI, Iss. 1, p.p. 13-19, ISSN NO. 0973-8150, (2010). 5. Venkata Reddy G a., C. Venkata Prasad a, K. Chowdoji Rao a T. Shobha Rani b and M.C.S. Subha, b, Tensile and Lignocellulosic Properties of Prosopis Chilens- is Fabric. Journal of Applied Polymer Science, Vol. 117, No. 5, 907-2914, (2010). 6. C. Venkata Prasad a, K. Chowdoji Rao a, Venkata Reddy G a, Yong-Ha Kim * T. Shobha Rani b and M.C.S. Subha b, A Study on Ligno-Cellulosic Fabric Hardwikia Binata. Journal of Applied Polymer Science, Vol. 115, No. 5, 2806-2812, (2010). 7. T. Shobha Rani, M.C.S. Subha, Venkata Reddy, G. Tensile Properties of Kapok/Sisal- Natural Fabrics Reinforced Polyester Hybrid Composites Bulletin on Chemical Sciences, Vol. VI, Issue I, p.p. 23-31, ISSN NO. 0973-8134 (2009). 8. C. Venkata Prasad a, K. Chowdoji Rao a, Venkata Reddy G a, T. Shobha Rani b, M.C.S. Subha, Characterization and Studies of Ligno-Cellulosic Fabric Grewia Tenax. Journal of Bioresources, (Accepted J. Bio-Resources -10-847). 9. M. Ashok Kumar, Venkata Reddy G *, K. Hema Chandra Reddy, Y. Mohan Reddy T. Shobha Rani b, Chemical Resistance and Tensile Properties of Epoxy/ Hybrid Fiber (Glass/Jute) Composites Journal of Reinforced Plastics and Composites, (Accepted - JRP-10-0045). 10. B.Yerriswamy 1, C. Lakshmi Narayana Reddy 1, C.Venkata Prasad 2, M.C.S.Subha 1, K.Chowdoji Rao 2, G. Venkata Reddy 3. Controlled Release Studies of 5-Flurouracil through Poly (vinyl caprolactam-co-vinyl acetate) Microspheres, [Accepted- Asian Journal of Pharmacy]. 11. C.Venkata Prasad, B.Yerriswamy, H.Sudhakar, T. Shobharani, M.C.S.Subha, K. Chowdoji Rao,. Preparation and Characterization of 4A zeolite filled mixed matrix membranes for pervaporation dehydration of Iso propyl alcohol, Journal of Applied Polymer Science, Vol. 121, 1521-1529, (2011). 12. E. Dillivara Prasad, M. Mastan, T. Shobha Rani, M. Siddalingesh, G. Venkata Reddy. Synthesis and Biological Evaluation of (E)-3-(2-(4-Substituted Phenyl)-1H-Indole-
3-YL)-(4-Substituted Phenyl) Prop-2-EN-1-One as Anti-Inflammatory Agents International Research Journal of Pharmacy, Vol. 12, No. 3, ISSN 2230-8407, (2012). 13. E. Dillivara Prasad, M. Mastan, T. Shobha Rani, Synthesis and Evaluation of analgesic activity of novel series of Indole derivatives linked to Isoxazole moiety Der Pharmacia Lettre, Vol. 4, No. 5, ISSN 0975-5071, 1431-1437, (2012). 14. E. Dillivara Prasad, M. Mastan, T. Shobha Rani, Synthesis and Biological Evaluation of 2- aryl-3-isoxazolinyl- Indole derivatives as anti-inflammatory agents J. Applied Chemistry, Vol. 3, No. 1, ISSN 2278-2786, (2012). 15. Raja sekhar.c, T. Shobha Rani, G. Venkata Reddy. Molecular Docking Studies of Phenyl amino pyrimidine Derivatives as Janus Kinase Inhibitors. Int. Jour. of Pharmacy & Pharmaceutical Sci. Vol. 6, No. 2, ISSN 0975-1491, (2014). 16. Raja sekhar.c, T. Shobha Rani, G. Venkata Reddy. Pharmacophore Modeling, Atom based 3D-QSAR and Molecular Docking Studies of Pyrimido [5, 4-e] [1, 2, 4] triazine Derivatives as PLK 1 Inhibitors. Int. Jour. of Science Direct. Elsevier Publications. 17. Raja sekhar.c, T. Shobha Rani, G. Venkata Reddy. Pharmacophore generation & Atom based 3D-QSAR analysis of substituted aromatic bi cyclic compounds containing pyrimidine & pyrimidine rings as JAK 2 Inhibitors. 18. G. Venkata Reddy, S. Venkata Naidu, T. Shobha Rani, and M.C.S. Subha, Compressive, Chemical Resistance and Thermal Studies on Kapok/Sisal Fabrics Polyester Composites Journal of Reinforced Plastics and Composites, Vol. 28, No. 12, 1485-1494, (2009). 19. G. Venkata Reddy, S. Venkata Naidu and T. Shobha Rani, A Study on Hardness and Flexural Properties of Kapok/Sisal Composites Journal of Reinforced Plastics and Composites, Vol. 28, No. 16, 2035-2044 (2009). 20. G. Venkata Reddy, T. Shobha Rani, K. Chowdoji Rao and S Venkata Naidu, Flexural, Compressive and Inter Laminar Shear Strength Properties of Kapok/Glass Composites, Journal of Reinforced Plastics and Composites, Vol. 28, No. 14, 1665-1677 (2009). 21. G. Venkata Reddy, T. Shobha Rani, P. N. Khanam, K. John and S. Venkata Naidu, Chemical Resistance and Tensile Properties of Unsaturated Polyester and Epoxy /PMMA Blend Coated Ceiba Pentandra, Journal of Reinforced Plastics and Composites, Vol. 28, No. 02, 175-182, (2009). 22. N. Mithil Kumar Naidu, G. Venkata Reddy, S. Venkata Naidu, T. Shobha Rani, and M.C.S. Subha, Mechanical Properties of Coir/Glass Fiber Phenolic Resin Based Composites, Journal of Reinforced Plastics and Composites, 28.2605-2613, (2009).
23. G. Venkata Reddy, S. Venkata Naidu and T. Shobha Rani, Kapok/Glass Polyester Hybrid Composites: Tensile and Hardness Properties, Journal of Reinforced Plastics and Composites, Vol. 27, No. 16-17, 1775-1787, (2008). 24. G. Venkata Reddy, S. Venkata Naidu and T. Shobha Rani, Impact Properties of Kapok/Glass and Kapok/Sisal Hybrid Fabrics Reinforced Unsaturated Polyester Composites, Journal of Reinforced Plastics and Composites, Vol. 27, No. 16-17, 1789-1804, (2008). 25. G. Venkata Reddy, P. N. Khanam, T. Shobha Rani, K. Chowdoji Rao and S. Venkata Naidu, Chemical Resistance Studies of Kapok/Glass and Kapok/Sisal Hybrid Fabrics Reinforced Unsaturated Polyester Composites, Bulletin of Pure and Applied Sciences, Vol. 26C (NO.1): 17-25, (2007). COMMUNICATED RESEARCH PUBLICATIONS 1. Yong-Ha Kim *, Venkata Reddy G., T. Shobha Rani, Selective Discharge of Coarse Particles from a Cold-Mode Fluidized Bed Reactor of Fine Iron Ore". Iron & Steel Institute of Japan International, (Communicated-ISIJI-2008-466). 2. C.Venkata Prasad, H.Sudhakar, B.Yerri Swamy, G.Venkata Reddy, C.L.N Reddy, T. Sobha Rani, M. C. S. Subha, and K.Chowdoji Rao. Miscibility studies of NaCMC/PVA blends for Pervaporation dehydration of Isopropyl alcohol. (Communicated: J of Appl Polym Sci, MS.No: APP-2010-06-1990). 3. C.Venkata Prasad, B. Yerri Swamy, T. Sobha Rani, G.Venkata Reddy, A.B.V Kiran Kumar, M.C.S.Subha K. Chowdoji Rao. Synthesis, characterization and Triprolidine hydrochloride release behavior through Sodium alginate-g-hydroxy ethyl acrylate beads" (Under review: Design Monomers and Polymers, MS.No:768061310). 4. C.Venkata Prasad, B.Yerri Swamy, T. Sobha Rani, C. Suryanarayana, G.Venkata Reddy, M.N. Prabhakar, K. Chowdoji Rao. Preparation and characterization of IPN beads for Controlled Release of Acrybutolol hydrochloride (Under Review: Iranian Polymer Journal, MS. No: IPJ-2010-02-5486. 5. C. Venkata Prasad, H. Sudhakar, G. Venkata Reddy, B. Yerri Swamy, C. L N Reddy, T. Sobha Rani, MCS Subha. Preparation and Characterization of Nano-Particle Filled Mixed Matrix Membranes for Pervaporation dehydration of Isopropyl alcohol (Under Review: Carbohydrate Polymers, MS.No: CARPOL-D-10-00916).
PAPERS PRESENTED AT THE SYMPOSIUMS/SEMINARS/CONFERENCES 1. Presented a Paper entitled Pyrimido [5, 4-e][1,2,4] triazine derivatives as PLK 1 inhibitors: Pharmacophore modeling, atom-based 3D-QSAR and Molecular Docking approach. in the Present status & Future Prospects of Modern Biotechnology & their Applications, Dept. of Biotechnology (March 27-29 th 2014.) held at the Dravidian University, Andhra Pradesh, India. 2. Paper presented in International seminar on ESMC-2013 held during 13-15 Nov. 2013 at Dept. of Chemistry, Vikrama Simha Puri University, Nellore. 3. Paper presented in National Seminar on NCRACP - 2013 held on 29 th Dec. 2013 at Dept. of Chemistry, S.V. University, Tirupati. 4. Presented a Paper entitled Pharmacophore modeling, atom-based 3D-QSAR and Molecular Docking Studies on Pycimido [5, 4-e] Triazine Derivatives as PLK 1 inhibitors in the International Conference on Biotechnology for Innovative Applications, Amrita Bioquest-2013 (October 11&14 th 2013.) held at the Amrita Vishwa Vidyapeetham, Amritapuri Campus, Kerala, India. 5. Presented a Paper entitled Validation of 1, 3, 5-triazine-2, 4-diamine derivatives as JAK2 inhibitors by Pharmacophore Modeling, Atom-Based 3D-QSAR and Docking Studies in the National Seminar on Recent Trends in Polymer Science& Technology RTPST- 2013 (June 29-30 th 2013.) held at the Department of Polymer Chemistry, Sri Krishnadevaraya University, Anantapur. A. P, India. 6. Presented a Paper entitled Synthesis, Characterization & Applications of Novel Quinoline Derivatives in the National Seminar on Advances in Polymeric Materials APM-2012 (March 16-17 th 2012.) held at the Department of Polymer Chemistry, Sri Krishnadevaraya University, Anantapur, A. P, India. 7. Presented a Paper entitled Synthesis, Characterization & Applications of Some New Indole Derivatives in the National Conference on Thrust Areas in Engineering (Jan 20-21 Th 2012.) held at the Global Academy of Technology, Bangalore, Karnataka, India.
8. Presented a Paper entitled Synthesis & Characterization of Some Indole Derivatives in the National Seminar on Recent Research Trends in Chemical Sciences RRTCS-2011 (Dec 23 rd 2011.) held at the Department of Chemistry, Sri Venkateswara University, Tirupati, A. P, India. 9. Presented a Paper entitled A Study on Ligno-Cellulosic Fabric Hardwikia Binata in the NCEPRS MACRO 08 (May 19 Th to 20 Th 2008) held at the Department of Polymer Science & Technology, SJ College of Engineering, Mysore India. 10. Presented a Paper entitled Flexural and Compressive Properties of Coir/sisal Natural Fiber Hybrid Composites in the Modern Trends in Analytical Methods of Analysis (Feb 25-27 Th 2008.) held at the Department of Chemistry, Sri Krishnadevaraya University, Anantapur, A. P, India. 11. Presented a Paper entitled Tensile Properties of Sisal/Coir Hybrid fiber Reinforced Unsaturated Polyester Composites (Eco-friendly Polymer Composites) in the National Seminar on Advances in Material Science (AMS-2007) (Jan.28-29, 2007), held at the Department of Material Science, Gulbarga University, Gulbarga, Karnataka, India. 12. Presented a Paper entitled Compatibility Studies on Solutions of Polymer Blends of Acacia with Poly (Acrylic Acid) in Water by Viscometric, Ultrasonic and Refractrometric Techniques in the 2 nd National Conference on Thermodynamics of Chemical and Biological Systems (October 30 Th to November 1 St, 2006.) held at the Department of Chemistry, Veer Narmad South Gujarat University, Surat, Gujarat, India. 13. Presented a Paper entitled Chemical Resistance and Tensile Properties of Epoxy /PMMA Coated Natural Fabric Ceiba Pentandra in the 2 nd National Conference on Thermodynamics of Chemical and Biological Systems (October 30 Th to November 1 St, 2006.) held at the Department of Chemistry, Veer Narmad South Gurat University, Surat, Gujarat, India. 14. Presented a Paper entitled Chemical Resistance and Tensile Properties of Epoxy Coated Natural Fabric Ceiba Pentandra (Kapok) in the Role of Chemistry in Emerging areas of Biology and Industries (March 25 Th to 26 Th 2006.) held at the Department of Chemistry, Sri Krishnadevaraya University, Anantapur, A. P, India.
15. Presented a Paper entitled Mechanical Properties of Blended Hybrid Fiber Composites in the National Conference on VIT Pragana-2K11 (January 25 Th 2011.) Organized by Dept. of Humanities & Sciences, Vemu Institute of Technology, P. Kothakota, Chittoor, A. P, India. POSTER PRESENTATIONS 16. Presented a Paper entitled Molecular Docking Studies of 1, 3-Thiazolidin-4-One Derivatives as PLK 1 Inhibitors in the 2 nd International Symposium on Frontiers in Pharmaceutical Research and Nanotechnology, Nanopharma-2012 (September 28 & 29 th 2013.) organized by Clinfocus Research Pvt. Ltd., India and Mohamed Sathak A. J. College of Pharmacy, Chennai, India. 17. Presented a Poster entitled Combinatorial and Computational Approaches in Identification of BRCA Ligands by Structure and Ligand-Based Virtual Screening in the National Seminar on Advances in Polymeric Materials APM-2012 (March 16-17 th 2012.) held at the Department of Polymer Chemistry, Sri Krishnadevaraya University, Anantapur, A. P, India. 18. Presented a Poster entitled, Selective Discharge of Coarse Particles from a Cold-Mode Fluidized Bed Reactor of Fine Iron Ore in the National Seminar on Recent Developments in Inorganic and Organic Materials and Electro-organic Synthesis (RDIOMES-2010) (February 26 th - February 27 th, 2010), held at the Department of Chemistry, Sri Krishnadevaraya University, Anantapur, A. P, India. 19. Presented a Poster entitled, Flexural Properties of Kapok/Glass Hybrid Fabric Reinforced Unsaturated Polyester Composites in the National Seminar on Advances in Material Science (AMS-2007) (Jan.28-29, 2007), held at the Department of Material Science, Gulbarga University, Gulbarga, Karnataka, India. WORKSHOPS ATTENDED 20. Attended the Two day workshop on Growth with Resource Enhancement of Environment & Nature on 14 th -15 th October 2011 held at the Andhra Pradesh Pollution Control Board & Dept. of Civil Engineering, Brindavan Institute of Technology &Science (BITS), Kurnool, A.P, India. 21. Attended the One day National Seminar on Emerging Trends in Advanced Material Science &Nanotechnology on 28 th January 2011 Organized by Dept. of Humanities & Sciences Kuppam Engineering College, KES Nagar, Kuppam, Chittoor, A. P, India.
22. Attended the Two day workshop on Combating Climate Change on 18 th -19 th March 2010 held at the Andhra Pradesh Pollution Control Board & Dept. of Chemical Engineering, JNTUA College of Engineering, Anantapur, A.P, India. 23. Attended the Two day workshop on Multi Media and its Applications on 8 th -9 th November 2010 held at the Dept. of Computer Science, Kuppam Eng. College, Kuppam, A.P, India.