AUDEC02ff.QXD 14/6/07 4:04 PM Page 12 Chapter 2: Atoms, Molecules, and Life Resource Directory Present Figures, Illustrations, Photos, and Tables Figure.JPEG Transparency PowerPoint 2-1 02_F01.jpg T-5 X 2-2 02_F02.jpg T-6 X 2-3 02_F03.jpg T-7 X 2-4 part a and b 02_F04ab.jpg T-8 X 2-4 part c 02_F04c.jpg X 2-5 02_F05.jpg T-7 X 2-6a 02_F06a.jpeg T-9 X 2-6b 02_F06a.jpeg X 2-7 02_F06a.jpeg T-7 X 2-8 02_F06a.jpeg T-7 X 2-9 02_F06a.jpeg X 2-10 02_F06a.jpeg T-10 X 2-11 02_F06a.jpeg T-11 X 2-12 02_F06a.jpeg X 2-13a 02_F06.jpeg X 2-13b 02_F06.jpeg X 2-14 02_F06a.jpeg X 2-15 02_F06a.jpeg T-12 X 2-16a 02_F06a.jpeg X 2-16b 02_F06a.jpeg X 2-17 02_F06a.jpeg X 2-CO 02_F00.jpg X E2-1 parts a c T-13 X E2-1 part a and b 02_FE01ab.jpg X 02_FE01c.jpg X E2-2 02_FE02.jpg X 2-T1 02_T01.jpg X 2-T2 02_T02.jpg X 2-T3 02_T03.jpg X 12
AUDEC02ff.QXD 14/6/07 4:04 PM Page 13 Additional Instructor Resources Chapter 2 Atoms, Molecules, and Life 13 Resource Title Location Lecture Activity 1 Exercises in Chemical Bonding Instructor Resource Guide Lecture Activity 2 Atomic Personal Ads Instructor Resource Guide Lecture Activity 3 Atoms, Molecules, and Drug Design Instructor Resource Guide Lecture Activity 4 Specific Heat of Water and Body Temperature Instructor Resource Guide Lecture Resources Chapter 2 Instructor Resource Guide Clicker Questions in PPT Chapter 2 Instructor Resource CD Instructor Animation Presentation Chapter 2 Instructor Resource CD PH Blast Presentation Chapter 2 Instructor Resource CD Suggested Lecture Presentation Chapter 2 Instructor Resource CD Assess Resource Test Item File Testgen EQ Software WebCT ready Test Item File Blackboard ready Test Item File Filename 02_testbank.doc setup.exe webct_test_item_file.zip blackboard_test_item_file.zip Student Review Resources Resource Title Location Web Investigations Free Radicals and Aging Life on Mars Online Study Guide Key Terms Chapter 2 Instructor Resource Guide and Online Study Guide Thinking Through the Concepts Chapter 2 Instructor Resource Guide Figure Caption Questions Chapter 2 Instructor Resource Guide Chapter Summary Chapter 2 Student Study Guide and Online Study Guide Learning Objectives Chapter 2 Student Study Guide and Online Study Guide Chapter Quiz Chapter 2 Student Study Guide and Online Study Guide At-A-Glance Case Study: Walking on Water 2.1 What Are Atoms? Atoms, the Basic Structural Units of Matter, Are Composed of Still Smaller Particles Scientific Inquiry: Radioactivity in Research 2.2 How Do Atoms Interact to Form Molecules? Atoms Interact with Other Atoms When There Are Vacancies in Their Outermost Electron Shells Charged Atoms Called Ions Interact to Form Ionic Bonds Uncharged Atoms Can Become Stable by Sharing Electrons, Forming Covalent Bonds Hydrogen Bonds Are Electrical Attractions Between or Within Molecules with Polar Covalent Bonds 2.3 Why Is Water So Important to Life? Water Interacts with Many Other Molecules Links to Life: Health Food? Water Molecules Tend to Stick Together Water-Based Solutions Can be Acidic, Basic, or Neutral Water Moderates the Effects of Temperature Changes Water Forms an Unusual Solid: Ice Case Study Revisited: Walking on Water
AUDEC02ff.QXD 14/6/07 4:04 PM Page 14 14 Instructor Resource Guide Lecture Resources Case Study: Walking on Water 2.1 What Are Atoms? A. Atoms, the Basic Structural Units of Matter, Are Composed of Still Smaller Particles 1. Atom basic structural unit of matter (Figures 2-1, 2-2, Table 2-1) a. Atomic nucleus positively charged protons and neutrons b. Negatively charged electrons orbit atomic nucleus 2. Elements atoms with same number of protons (atomic number) a. Isotopes same element; different number of neutrons b. Radioactive isotopes release energy 3. Electrons travel within specific regions called shells that correspond to different energy levels a. Electron shells allow interactions, or bonds with other atoms 2.2 How Do Atoms Interact to Form Molecules? A. Atoms Interact with Other Atoms When There Are Vacancies in Their Outermost Electron Shells 1. Chemical bonds hold atoms together; gain, loss, sharing of electrons a. Ionic bonds gain or loss of electrons b. Covalent bonds sharing of electrons c. Hydrogen bonds between polar molecules 2. Chemical reactions making and breaking of chemical bonds (Table 2-2) B. Charged Atoms Called Ions Interact to Form Ionic Bonds (Figure 2-4) 1. Outermost electron shell is almost empty or almost full 2. Ions atoms become stable by gaining or losing electrons 3. Ionic bonds electrical attraction between positive and negative ions (Figure 2-5) C. Uncharged Atoms Can Become Stable by Sharing Electrons, Forming Covalent Bonds (Figure 2-6) 1. If outermost electron shell is partially full may form covalent bond 2. Covalent bonds atoms become stable by sharing electrons a. Nonpolar covalent bonds equal sharing of electrons b. Polar covalent bonds unequal sharing of electrons (H 2 O) 3. Free radicals unstable molecules; unfilled outermost shell (Figure 2-9) a. Steal electrons to complete outermost electron shells b. Antioxidants donate electrons to free radicals to stabilize them D. Hydrogen Bonds Are Electrical Attractions Between or Within Molecules with Polar Covalent Bonds 1. Hydrogen bonds bonds between parts of polar molecules (Figure 2-10) 2. Responsible for unique properties of water Lecture Activity 2.1: Exercise in Chemical Bonding Lecture Activity 2.2: Atomic Love Connection Lecture Activity 2.3: Atoms, Molecules, and Drug Design 2.3 Why Is Water So Important to Life? A. Water Interacts with Many Other Molecules (Figures 2-11, 2-12) 1. Water is capable of dissolving a wide range of substances 2. Hydrophilic molecules attraction to water (ions, polar molecules) 3. Hydrophobic molecules no attraction to water (do not dissolve) B. Water Molecules Tend to Stick Together 1. Cohesion water molecules stick together (Figure 2-13) 2. Surface tension surface of water is resistant to being broken 3. Adhesion water sticks to polar surfaces C. Water-based Solutions Can Be Acidic, Basic, or Neutral (Figures 2-14, 2-15) 1. Pure water contains equal amounts of hydrogen and hydroxide ions 2. Acidic solutions more hydrogen ions (H + ) than hydroxide ions (OH ) 3. Basic solutions more hydroxide ions (OH ) than hydrogen ions (H + ) 4. ph scale expresses degree of acidity of a solution; scale from 1 14 a. Acids have a ph below 7 (more H + than OH ) b. Bases have a ph above 7 (More OH than H + ) c. Water has a ph of 7 (equal amount of H + and OH ) 5. Buffers compound that maintains the ph of a given solution
AUDEC02ff.QXD 14/6/07 4:04 PM Page 15 D. Water Moderates the Effects of Temperature Changes (Figure 2-16) 1. Water has a high specific heat a. Specific heat energy required to heat 1 gram by 1 C. b. Takes more energy to heat water than most substances 2. Water has a high heat of vaporization a. Heat of vaporization heat required to vaporize a substance b. Takes more energy to vaporize water than most substances 3. Water has a high heat of fusion a. Heat of fusion energy that must be removed to freeze a liquid b. Water freezes more slowly than many other liquids Lecture Activity 2.4: Specific Heat of Water and Body Temperature E. Water Forms an Unusual Solid: Ice (Figure 2-17) 1. Most liquids become more dense when solid 2. Unique property of ice less dense than liquid water Case Study Revisited: Walking on Water Chapter 2 Atoms, Molecules, and Life 15 Key Terms acid acidic antioxidant atom atomic nucleus atomic number base basic buffer calorie chemical bond chemical reaction cohesion compound covalent bond electron electron shell element free radical hydrogen bond hydrophilic hydrophobic hydrophobic interaction ion ionic bond isotope molecule neutron nonpolar covalent bond ph scale polar covalent bond proton radioactive solvent surface tension Figure Caption Questions Figure 2-2 Electron shells in atoms Why do atoms that tend to react with other atoms have outer shells that are not full? Atoms with non-full outer shells are reactive, with a strong tendency to form bonds with other atoms, and thus suitable for roles in the myriad chemical reactions of metabolism and for forming the complex molecules from which living things are constructed. Life s most prevalent molecules are notable for their tendency to participate in covalent bonds. Figure 2-6 Covalent bonds involve shared electrons In water s polar bonds, why is oxygen s pull on electrons greater than hydrogen s? Oxygen s nucleus has eight protons, while hydrogen s has only a single proton. So the positive charge of the oxygen nucleus is far stronger than that of the hydrogen nucleus. Figure 2-9 Free Radical Damage How do free radicals damage biological molecules? Free radicals steal electrons from nearby molecules causing destruction of those molecules. Consider This Hints If water molecules were nonpolar, there would be no hydrogen bonds between water molecules. As a result, we might hypothesize that water would be less effective as a solvent and that it would have less internal cohesion. Think about how such changes would affect such biological processes as transport of substances in blood and movement of water and nutrients in plants.
AUDEC02ff.QXD 14/6/07 4:04 PM Page 16 16 Instructor Resource Guide Thinking Through the Concepts 1. What are the six most abundant elements that occur in living organisms? O, C, H, N, Ca, P 2. Distinguish among atoms and molecules; elements and compounds; and protons, neutrons, and electrons. An atom is the smallest particle of an element that still retains the properties of that element. A molecule consists of two or more atoms chemically bonded together. Protons are positively charged subatomic particles found in the atomic nucleus. Neutrons are uncharged subatomic particles found in the atomic nucleus. Electrons are negatively charged subatomic particles found in electron shells around the atomic nucleus. 3. Compare and contrast covalent bonds and ionic bonds. Covalent bonds involve the sharing of a pair of electrons between two atoms. Ionic bonds result from electrical charge attraction following the transfer of one or more electrons between atoms. 4. Why can water absorb a great amount of heat with little increase in its temperature? Water has a high specific heat, so energy inputs break hydrogen bonds between water molecules rather than causing the water molecules to move more rapidly, which would make the temperature rise. 5. Describe how water dissolves a salt. How does this phenomenon compare with the effect of water on a hydrophobic substance such as corn oil? Water molecules surround the ions, insulating them from their electrical attractions for each other, which causes the ions to separate. Oil molecules aggregate in water due to hydrophobic interaction. 6. Define acid, base, and buffer. How do buffers reduce changes in ph when hydrogen ions or hydroxide ions are added to a solution? Why is this phenomenon important in organisms? An acid is a substance that gives off hydrogen ions. A base is a substance that combines with hydrogen ions. A buffer is a compound that tends to maintain a solution at a constant ph by accepting or releasing hydrogen ions in response to small changes in hydrogen ion concentration. Applying the Concepts Hints 1. Think about what the molecule would need to form hydrogen bonds with water, and what it would need to interact with hydrophobic fats. Now imagine these different parts on the same molecule. 2. What would happen to ice that formed in a small pond or lake? In what direction would small bodies of water freeze? Think about the poles how would seals and polar bears be affected? 3. Think about the evaporation of water and specific heat. Now consider how high humidity influences the ability of water to evaporate. 4. Oxygen is essential to extract usable energy efficiently from food molecules (see Chapter 8). But whenever oxygen is used in the body, it tends to produce free radials. This presents a dilemma! Lecture Activity 1: Exercise in Chemical Bonding Estimated Time to Complete: 10 25 minutes Section Reference 2.2 How Do Atoms Interact to Form Molecules? Introduction This activity is a basic introduction to the concept of chemical bonding. This is a short, in-class exercise that can follow an introductory discussion of atomic structure and bonding. Students will take the number of their birth month as their atomic number. Given this information, they will be able to determine the configuration of electrons. They will then be able to determine how this atom will interact with other atoms, if at all. Students will form groups with other students to form ions or molecules and will present their bond formation to the class.
AUDEC02ff.QXD 14/6/07 4:04 PM Page 17 Chapter 2 Atoms, Molecules, and Life 17 Chapter Concepts Addressed: 1. Students learn about atomic structure and electron configurations 2. Students apply their knowledge of electron configuration to atomic bonding 3. Students interact with classmates to form ionic or covalent bonds Materials Needed No specific materials are needed. Procedures 1. Instruct the students to identify their birth month on a piece of paper. They will consider the number of their birth month to be their atomic number. 2. Next, instruct them to draw their appearance as an atom. Specifically, they must determine their electron configuration and how many electrons are in their outermost shell. 3. Using this information, they should determine what type of bond they might like to form to become stable and fill the outermost shell. 4. Students must then form a bond with another classmate so that both atoms become stable. 5. These student groups of bonded atoms can then present their bond to the class and explain why they are both now stable. Alternatively, to save class time, they could write this information on a sheet of paper to be handed in. Assessment Suggestions Evaluate the student bonds that are formed and assign a grade for class participation. Lecture Activity 2: Atomic Love Connection Estimated Time to Complete: 25 30 minutes Section Reference 2.2 How Do Atoms Interact to Form Molecules? Introduction This activity reinforces students understanding of atomic structure, as well as ionic and covalent bonds. These topics should be covered in class prior to beginning this activity. In this activity, the students will either choose or be assigned a particular element and will write a personal ad for that atom. This ad should describe the properties of the atom and also describe what type of bond the atom would like to form. Following completion of the handout, students should share their ads with each other to find a good bonding match between atoms. Chapter Concepts Addressed: 1. Students learn about the structure of atoms 2. Students apply their understanding of atomic structure to determine whether an atom is inert or reactive 3. Students learn how to determine whether an atom will form covalent or ionic bonds Materials Needed Handout included in this activity; periodic table for the entire class or for each student Procedures 1. Hand out worksheet with background information. 2. Students should work individually to write to their own personal ad for their atom. The instructor may choose to assign an element or students may choose from the elements listed on the worksheet. In larger classes, more than one student can be assigned the same element. 3. The students should first determine the atomic number of their element and how many electrons are in the outer shell. This information can then be used to determine if the atom is most likely to form a covalent or ionic bond. 4. Students can then interact with each other in groups to find matches to their ads. For example, a carbon ad would match up well with a hydrogen ad to form covalent bonds. Assessment Suggestions You may collect the student s sheets for grading or assign an in-class participation grade if the student reads their ad to the class.
AUDEC02ff.QXD 14/6/07 4:04 PM Page 18 Handout Atomic Love Connection Choose one of the following elements: carbon magnesium hydrogen nitrogen chlorine calcium oxygen sodium phosphorus sulfur potassium bromine 1. Determine the atomic symbol: 2. Use the periodic table to determine the atomic number: 3. Describe how you will determine if the atoms of your element are inert or reactive. 4. Use the characteristics of your atom to write a personal ad for it. Be creative! Your ad should include the following information. See the example below as a guide. Example: Fluorine(F); atomic number = 9 Personal ad: Single fluorine atom seeking another kind atom willing to donate one electron to add stability to my life. I currently have seven electrons in my outer shell and am willing to form an ionic bond with any atom who answers this ad. 5. When you are done, see if you can find another personal ad that is a good match for yours (your atomic love connection). Write your match below. What kind of bond will you form?
AUDEC02ff.QXD 14/6/07 4:04 PM Page 19 Lecture Activity 3: Atoms, Molecules, and Drug Design Chapter 2 Atoms, Molecules, and Life 19 Estimated Time to Complete: 15 25 minutes Section Reference 2.2 How Do Atoms Interact to Form Molecules? Introduction This activity highlights a current example of the importance of understanding atoms and molecules. A short video demonstrates how researchers must examine the bonding between hundreds of different atoms to design new drugs. Scientists must then assess how those drugs will interact by studying the atoms that compose the tissues of the human body that will be affected. This exercise can follow the class discussions on atomic bonding or can be used as part of the introduction to the topic in class. A worksheet is provided with questions for students to answer after reading the article and/or watching the video. Chapter Concepts Addressed: 1. Students apply their knowledge of atoms to real-life research 2. Students gain an understanding of the role of atoms in designing effective medications Materials Needed Computer with projector capabilities or computer lab with access for student groups to watch the video clip at their own stations; worksheet to accompany video clip (Please note: This video clip is available at no charge on the Internet at the Web site listed below.) Procedures 1. Hand out the worksheet with questions that the students will be answering. 2. Access the following link on the World Wide Web: http://agnews.tamu.edu/dailynews/stories/bich/jul1602a.htm 3. Click on one of the links under Video on the right-hand side of the Web page. (You must determine if you want to play the clip using QuickTime or RealPlayer.) 4. Allow the students to answer the questions on the worksheet as they watch the video. 5. You may discuss the answers in class or collect the sheets to grade them. Assessment Suggestions You may collect the students question sheets to grade. Alternatively, you may pose the following question as a homework assignment: What is the importance in medicine of understanding atoms and molecules? Ask the students to write a paragraph answering this question, using what they just learned as a starting point.
AUDEC02ff.QXD 14/6/07 4:04 PM Page 20 Handout Atoms, Molecules, and Drug Design 1. According to the video, what must scientists be able to do in order to design a new drug? 2. How does the computer program shown in the video help scientists do their work? 3. How many atoms are present in the drug being tested in the video? 4. How many atoms are present in the receptor in the human body that the drug must interact with? 5. Using what you just learned, what knowledge of atoms and molecules is important for the scientists doing this research?
AUDEC02ff.QXD 14/6/07 4:04 PM Page 21 Lecture Activity 4: Specific Heat of Water and Body Temperature Chapter 2 Atoms, Molecules, and Life 21 Estimated Time to Complete: 20 25 minutes Section Reference 2.3 Why Is Water So Important to Life? Introduction This activity helps students apply their understanding of the specific heat of water to a biological concept. The ability to maintain body temperature is an important feature of the human body that is, in part, attributable to this important property of water. Chapter Concepts Addressed: 1. Students define the term specific heat 2. Students apply the specific heat of water to the human body s ability to maintain body temperature 3. Students examine how liquids of different specific heat could affect body temperature regulation Materials Needed Handout included with this activity; pens/pencils Procedures 1. This activity should be completed following a class discussion of the meaning of the term specific heat. 2. Give a copy of the handout to each student. Allow them to form groups of 2 3 students to work together to complete the worksheet. Alternatively, this could be a homework assignment. 3. You may either collect the sheet for grading or discuss the answers in class. 4. Important points to address are: A. The specific heat of a substance is defined as the amount of heat that must be absorbed or lost for 1 g of that substance to change its temperature by 1 ºC. B. Since the body is composed mainly of water with a high specific heat, the human body is able to resist changes in body temperature. Therefore, it takes a long time for the human body to overheat. It will take less time for all of the space organisms to overheat because their specific heats are lower. Assessment Suggestions You may collect the students handouts to grade. Alternatively, you may assess the students involvement in the class discussion that follows completion of the worksheet.
AUDEC02ff.QXD 14/6/07 4:04 PM Page 22 Handout Specific Heat and Regulating Body Temperature Background Information: Our bodies are 80% water. Imagine that you work for NASA and have recently discovered many new life-forms on distant planets. Space probes have gathered some preliminary data about these living creatures. Specifically, you have learned that each life-form is composed primarily of another liquid rather than water. Work in small groups to answer the questions below. Preliminary data: Organism A: body composition is 77% ethyl alcohol (specific heat = 0.60 cal/g ºC) Organism B: body composition is 81% kerosene (specific heat = 0.47 cal/g ºC) Organism C: body composition is 83% seawater (specific heat = 0.94 cal/g ºC) Organism D: body composition is 81% sulfuric acid (specific heat = 0.35 cal/g ºC) Human body: body composition is 80% water (specific heat = 1.00 cal/g ºC) Questions: 1. Define the term specific heat. 2. It takes cal of heat to raise the temperature of 1 g of ethyl alcohol by 1 ºC. 3. You place one beaker of water on one hot plate and a beaker of sulfuric acid next to it on the same hot plate. Which one will heat up faster? Explain why? 4. If you were to place each organism in the direct sunlight on a warm day, which organism s body temperature will increase more rapidly than the human body? Which organism s body temperature will increase less rapidly than the human body? Explain why. (Use the term specific heat in your answer.) 5. Put the four organisms in order starting with the one whose body temperature will increase the fastest and proceeding to the one whose body temperature will increase the slowest.