Introduction: Themes in the Study of Life

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Chapter 1 Introduction: Themes in the Study of Life Edited by Shawn Lester PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with contributions from Joan Sharp

Overview: Inquiring About the World of Life Evolution is the process of change that has transformed life on Earth Biology is the scientific study of life Biologists ask questions such as: How a single cell develops into an organism How the human mind works How living things interact in communities

Life defies a simple, one-sentence definition Life is recognized by what living things do

Fig. 1-3 Order Evolutionary adaptation Response to the environment Regulation Energy processing Growth and development Reproduction

Concept 1.1: Themes connect the concepts of biology Biology consists of more than memorizing factual details Themes help to organize biological information

Evolution, the Overarching Theme of Biology Evolution makes sense of everything we know about living organisms Organisms living on Earth are modified descendents of common ancestors

Theme: New properties emerge at each level in the biological hierarchy Life can be studied at different levels from molecules to the entire living planet The study of life can be divided into different levels of biological organization

Fig. 1-4 Communities The biosphere Ecosystems Organs and organ systems 10 µm Cells Cell Organelles Populations Organisms Tissues 1 µm Atoms 50 µm Molecules

The Power and Limitations of Reductionism Reductionism is the reduction of complex systems to simpler components that are more manageable to study For example, the molecular structure of DNA Often for the sake of simplicity and understanding, biologists and other scientists generalize in order to facilitate understanding.

Theme: Organisms interact with their environments, exchanging matter and energy Every organism interacts with its environment, including nonliving factors and other organisms Both organisms and their environments are affected by the interactions between them For example, a tree takes up water and minerals from the soil and carbon dioxide from the air; the tree releases oxygen to the air and roots help form soil

Ecosystem Dynamics The dynamics of an ecosystem include two major processes: Cycling of nutrients, in which materials acquired by plants eventually return to the soil The flow of energy from sunlight to producers to consumers

Fig. 1-5 Sunlight Ecosystem Cycling of chemical nutrients Producers (plants and other photosynthetic organisms) Chemical energy Heat Consumers (such as animals) Heat

Energy Conversion Work requires a source of energy Energy can be stored in different forms, for example, light, chemical, kinetic, or thermal The energy exchange between an organism and its environment often involves energy transformations Energy flows through an ecosystem, usually entering as light and exiting as heat

Theme: Structure and function are correlated at all levels of biological organization Structure and function of living organisms are closely related For example, a leaf is thin and flat, maximizing the capture of light by chloroplasts

Fig. 1-6 (a) Wings (b) Bones Infoldings of membrane Mitochondrion (c) Neurons 100 µm (d) Mitochondria 0.5 µm

Theme: Cells are an organism s basic units of structure and function The cell is the lowest level of organization that can perform all activities required for life All cells: Are enclosed by a membrane Use DNA as their genetic information The ability of cells to divide is the basis of all reproduction, growth, and repair of multicellular organisms

A eukaryotic cell has membrane-enclosed organelles, the largest of which is usually the nucleus By comparison, a prokaryotic cell is simpler and usually smaller, and does not contain a nucleus or other membrane-enclosed organelles Bacteria and Archaea are prokaryotic; plants, animals, fungi, and all other forms of life are eukaryotic

Fig. 1-8 Eukaryotic cell Membrane Cytoplasm DNA (no nucleus) Prokaryotic cell Membrane Organelles Nucleus (contains DNA) 1 µm

Theme: The continuity of life is based on heritable information in the form of DNA Chromosomes contain most of a cell s genetic material in the form of DNA (deoxyribonucleic acid) DNA is the substance of genes Genes are the units of inheritance that transmit information from parents to offspring

DNA Structure and Function Each chromosome has one long DNA molecule with hundreds or thousands of genes DNA is inherited by offspring from their parents DNA controls the development and maintenance of organisms

Genes control protein production indirectly DNA is transcribed into RNA then translated into a protein An organism s genome is its entire set of genetic instructions

Advances in systems biology at the cellular and molecular level depend on High-throughput technology, which yields enormous amounts of data Bioinformatics, which is the use of computational tools to process a large volume of data Interdisciplinary research teams

Theme: Feedback mechanisms regulate biological systems Feedback mechanisms allow biological processes to self-regulate Negative feedback means that as more of a product accumulates, the process that creates it slows and less of the product is produced Positive feedback means that as more of a product accumulates, the process that creates it speeds up and more of the product is produced exs. childbirth oxytocin speeds up contractions, blood clotting

Fig. 1-13a Negative feedback A Enzyme 1 B Excess D blocks a step D D D C Enzyme 2 Enzyme 3 D (a) Negative feedback

Fig. 1-13b W Enzyme 4 Positive feedback + X Enzyme 5 Excess Z stimulates a step Z Z Z Y Enzyme 6 Z (b) Positive feedback

Concept 1.2: The Core Theme: Evolution accounts for the unity and diversity of life Nothing in biology makes sense except in the light of evolution Theodosius Dobzhansky Evolution unifies biology at different scales of size throughout the history of life on Earth

Organizing the Diversity of Life Approximately 1.8 million species have been identified and named to date, and thousands more are identified each year Estimates of the total number of species that actually exist range from 10 million to over 100 million (All Species Inventory)

Grouping Species: The Basic Idea Taxonomy is the branch of biology that names and classifies species into groups of increasing breadth Domains, followed by kingdoms, are the broadest units of classification

Fig. 1-14 Species Genus Family Order Class Phylum Kingdom Domain Ursus americanus (American black bear) Ursus Ursidae Carnivora Mammalia Chordata Animalia Eukarya

The Three Domains of Life The three-domain system is currently used, and replaces the old five-kingdom system Domain Bacteria and domain Archaea comprise the prokaryotes Domain Eukarya includes all eukaryotic organisms

Fig. 1-15 (a) DOMAIN BACTERIA (b) DOMAIN ARCHAEA (c) DOMAIN EUKARYA Protists Kingdom Plantae Kingdom Fungi Kingdom Animalia

The domain Eukarya includes three multicellular kingdoms: Plantae Fungi Animalia Other eukaryotic organisms were formerly grouped into a kingdom called Protista, though these are now often grouped into many separate kingdoms

Fig. 1-15c Protists Kingdom Plantae Kingdom Fungi (c) DOMAIN EUKARYA Kingdom Animalia

Unity in the Diversity of Life A striking unity underlies the diversity of life; for example: DNA is the universal genetic language common to all organisms Unity is evident in many features of cell structure

Fig. 1-16 15 µm 5 µm Cilia of Paramecium 0.1 µm Cross section of a cilium, as viewed with an electron microscope Cilia of windpipe cells

Charles Darwin and the Theory of Natural Selection Fossils and other evidence document the evolution of life on Earth over billions of years

Charles Darwin published On the Origin of Species by Means of Natural Selection in 1859 Darwin made two main points: Species showed evidence of descent with modification from common ancestors Natural selection is the mechanism behind descent with modification Darwin s theory explained the duality of unity and diversity

Fig. 1-18

Darwin observed that: Individuals in a population have traits that vary Many of these traits are heritable (passed from parents to offspring) More offspring are produced than survive Competition is inevitable Species generally suit their environment

Darwin inferred that: Individuals that are best suited to their environment are more likely to survive and reproduce Over time, more individuals in a population will have the advantageous traits In other words, the natural environment selects for beneficial traits

Fig. 1-20 1 Population with varied inherited traits. 2 Elimination of individuals with certain traits. 3 Reproduction of survivors. 4 Increasing frequency of traits that enhance survival and reproductive success.

The Tree of Life Unity in diversity arises from descent with modification For example, the forelimb of the bat, human, horse and the whale flipper all share a common skeletal architecture Fossils provide additional evidence of anatomical unity from descent with modification

Darwin proposed that natural selection could cause an ancestral species to give rise to two or more descendent species For example, the finch species of the Galápagos Islands Evolutionary relationships are often illustrated with tree-like diagrams that show ancestors and their descendents

Fig. 1-22 COMMON ANCESTOR Warbler finches Insect-eaters Seed-eater Bud-eater Green warbler finch Certhidea olivacea Gray warbler finch Certhidea fusca Sharp-beaked ground finch Geospiza difficilis Vegetarian finch Platyspiza crassirostris Mangrove finch Cactospiza heliobates Tree finches Insect-eaters Woodpecker finch Cactospiza pallida Medium tree finch Camarhynchus pauper Large tree finch Camarhynchus psittacula Small tree finch Camarhynchus parvulus Ground finches Seed-eaters Cactus-flowereaters Large cactus ground finch Geospiza conirostris Cactus ground finch Geospiza scandens Small ground finch Geospiza fuliginosa Medium ground finch Geospiza fortis Large ground finch Geospiza magnirostris

You should now be able to: 1. Briefly describe the unifying themes that characterize the biological sciences 2. Distinguish among the three domains of life, and the eukaryotic kingdoms 3. Distinguish between the following pairs of terms: discovery science and hypothesisbased science, quantitative and qualitative data, inductive and deductive reasoning, science and technology