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Jurnl Phrmceuticl Reerch & Cl icl Prctice, July- S ept 2011; R eerch A rticle Culturl Apttin V lin Hi Trnlte Multiimeninl De Q uetinnire ( MDQ) Aei ng Qul y Lif e P tient Ty pe 2 Di te Mellu Inin Subject. *S. S. Pwr 1, P. A. Thkurei 2. 1. Re erch S chlr K rpgm Univer y, Cimbr e At. P r er, Deprtent Phrmcl g y, Shg Techni cl Eucti n Sciet y, S mt. Khib i N vle C llege Phrmcy, Knhw, (Bk)-411048, Pune, Mhrhtr, Ini. 2. Generl Mnger, Scientific Affir, Inu Bech Privte Lime, Pune-411048, Mhrh tr, I ni. K eywr: HR, c ulturl pttin, mu ltiimeninl i te q u etinnire, p ychmetric nly R eceive 26 My 2011 Receive reve m 28 June 2011 Accepte 04 July 2011 * Authr f r C rrepnence: S. S. P wr R eerch Schlr K rpgm U nivery, C imbre At. Pr er, D eprtment P hrmclgy, S hg Technicl Euctin S ciety, S mt. K hibi N vle Cllege P hrmcy, K nhw, ( Bk) - 411048, P une, M hrhtr, Ini. E- m il: hriknt_pwr12@reiffmil.cm A BSTRACT evelpm ent v li Helt h Relte Quly L ife (H R ) quetinn ire h ge imprtnc e i n bth c licl reerch n e e mngement. m im th tu y crry ut cultur l pttin, trnltin vlin Multiimenin l e quetinn ire ( M DQ) i n H i lngu ge. M DQ i ne quetinn ire u e i n e g Q uly L ife ( ) i tic ptient. M DQ quetinnire i i n Englh lngug e ce q uetinnire elf mtere c nnt b e u e i n m jry Inin ptient ut c ulturl ptin vlin. im thi w rk w ree multe n vle n pp rprely trnlte Hi quetinn ire 40 i tem cle p er th e recmmene Eurpe n rgniztin f r reerch t retment cnc er ( EORTC) guiel e. Demgrph ic tuy h w verge ge 57 yer S D 9.12. te t rete t relibily t he tercl crreltin w tfcry w hen ubmpl e 50 ptient w t ete w h 4 w eek terv l. P ern crrelti n c efficient w f un ignificnt thir ub cle ( p<0. 0005). Pychmetric nly upprte r elibily vliy 41 e m quetinni re w h t hree ubcle: L erng e ( C rnbch α v lue = 0. 872), elf c re ctiv ie ( C rnbch α vlue = 0.9613), elf c re prgrm ( Crnbch α vlu e = 0.9636). A bve tt ticl nly reve l th t i tic p tient hve prpe r lerng e, elf c re bily n y prticipte elf c re prgrm. M DQ i n H i lngu ge w ill b e uef ul t tuy t he i tic ptient l cn u e f r c licl t ril b y c licin i n I ni. S. S. P wr et.l, JPRCP 2011; 1( 3 ) 7

Reerch Phrmceuticl urnl J e Prctic Clicl &, y ul J - ; 2011 ept S : (3) 1 7-1 1 S. S. 1 JPRCP 2011; et.l, wr P ( ) 3 8 I N TRODUCTIO N e D y qul n effect ignificnt h lwy Ptient (). f em much very tretment ily relte ee h emtinl cmplictin, lte cute threteng y y ffect generlly ic ptient. tyle cue wrt cme ptient jr m ll i cil phyicl, n effect g. well ychlgicl p cntg cncept multiimeninl ue cil pychlgicl phyicl, recgnize cregly en h meure utcme imprtnt n enpt clic in A [1]. urvivl verll free ee re quetinnire vle vriety e : meure vilble g well meure, quly tretment e quetinnire, pychlgicl quetinnire, tfctin e, jutment pecific e ver cntrl perceive lief, helth elf e brrier e, - cre, e Multiimeninl [2]. etc ne (MDQ) quetinnire eg ue quetinnire Hwever, [3]. ptient ic uetinn q lnguge Englh ire cnnt mtere, elf ce ic Inin mjry ue ptin culturl ut ptient wrk ur im vlin. pprprely n multe ree quetinnir Hi rnlte t per e guiele recmmene vilble mke bjective ultimte elg cmmuny pecific clicin ptient ic pekg Hi reerch. prctice clicl y y tuy tinle R prev cree he T chrnic lence greter cll 5] [4, illnee vnce [6] empwerment ptient hve 8] [7, technlgy mtin ptient ntribute rg teret c tretment. utcme but view nly cn tretment impct e m me ptient kg ure ptient, nly knwn re utcme tfie hw evlutin uch tkg while ne ne verifie cnnt e tretment uch utcme, Or evience. r phyic eprt r cn functin, l r. berve trnlte MDQ like lnguge ifferent vle [9] Englh Spnh Germn, Ini In tuie. furr ue vle trnlte nt MDQ vi mke im We lnguge. i H lble utily furr MDQ vle Ini. tuie ATERIALS AND METHODS M guiele uggete pte We Eurpen given prceure trnltin tretment reerch rgniztin uthr One [10]. (EORTC) cncer cte wh mnger prject lcl ebriefg cgnive ut crry peker ntive He terview. trget reie lnguge trget methlgy uggete cuntry. fllw: rwr trnltin: F rig trnltin rwr F lnguge l verin) urce clle (l lnguge Hi uetinnire q Inin tw epenently ne tuy knew wh trnlr, bjective. n I Trnlr trnlr lnguge ccuptinl h lnguge ntive i H y ver g Englh. ver cmm l wh ileclgt II trnlr h peker Hi ntive Englh. ver cmm g extremely quetinnire Hi termee Firt wr tw frm me lc where rnltin t prject l quetin cue ech mnger meetg pernl fter trnlr

J urnl Phrmceuticl Reerch & Clicl Prctice, July- S ept 2011; telephnic cnervtin flly firt termee Hi quetinnire f rme. B ck trnltin: firt termee Hi quetinnire v erin generte ubmte bck- trnltin, ne tw r trnlr, reient Ini. Trnlr I n ficil trnlr hvg vt experience lnguge trnltin trnlr II ileclgt wh l ntive Hi peker. Bth m h extremely g cmm ver Englh well H i lnguge. Subequently, ubmte cmmtee expert, cmpe 6 multiciplry e pecilt, Englh lnguge m. E ch em rigl quetinnire trnlte verin cmpre reltin emntic/iimtic equivlence rer ure crrect trnltin bt ecn i ntermee quetinnire. Difficultie encunntre firt i ntermee Hi queti nnire. tw quetinnire were evlute prject crr. re were n ifference fun firt eleven quetin. In quetin twelve bth quetin h imilr meng but wr त थ fun mre pprpre t he quetin trnlr II. N ifference were fun quetin ectin II. In ectin III, quetin ecn, five even trnlr I wrte श क कर, श कर me quetin trnlr II, but wr श क कर f un mre pprpre ue mre cmmnly pken lnguge. Hence e quetin trnlr I cniere firt termee q uetinnire. P ilt tetg fl ecn termee MDQ n mtere 20 ptient S tr trict Mhrhtr type 2 e wh h never een quetinnire m fl quetinnire. e ptient h never een MDQ quetinnire e were ll ntive Hi peker. Ptient ppultin cmpre (14) femle ( 6) mein ge yer. All ic ptient were ke fill MDQ quetinnire were terviewe ifficulty unertg quetin ir meng. y were l ke quetin tht cnfue, ivert n upet m urg fillg q uetinnire. Difficultie t etg encuntere pilt mjr ifficultie cme cr while tteng i nclue: quetin ptient P tient 1 ( SK), ugget wr द श प रन म te प रन म quetin ix. Ptient 4 (SP) h ifficulty unertg cle quetinnire ectin III. Th cle cnt बल क ल वश व स न ह ह! mifie बल क ल म हत वपण न ह ह! Ptient 3 (AG) ugget wr उ पय क त ह! cle quetin 11 ectin III. Ptient 5 (MA) uggete chnge wrg वश व स ह! te बल क ल र क न ह स कत! quetin n 13 ectin III. Thu ll ptient f trnlte MDQ ey fill few crrectin me per ir c nvenience fill quetinnire. V lin Stuy S tuy ppultin mple ize: Ptient wh prticipte vlin tuy were Hi pekg ult ver ge 18 clicl ign e mellu type 2 t time firt tuy v. A tl 50 ic ptient (12 femle 38) mle were cheule prticipte tuy. S. S. P wr et.l, JPRCP 2011; 1( 3 ) 9

J urnl Phrmceuticl Reerch & Clicl Prctice, July- S ept 2011; 50 ptient were ke fill quetinnire. After tervl 4 w eek me tuy ppultin ke fill quetinnire. Ptient were n regulr tretment tween v. M eurement utcme: HR ic ptient meure ug 40 em cle. quetinnire cnt three imenin HR: Lerng e ( 16 Item), ll 16 em were meure n 7- pt repne cle frm nt t ll t extremely. Self cre ctivie (12 I tem), ll 12 em were meure n 7- pt repne cle frm never very ten. n elf cre prgrm (13 Item), ll 13 em were meure n 11- pt repne cle frm nt t ll c nfient very cnfient. O r vrible. Or t cllecte clue ge t time e, BMI, e relte c mplictin like chet p, ng, IHD, MI, nephrpthy, neurpthy, ily, trnplnt, turbnce vin, ctrct, retpthy, blne, urticri, ge t ign, ecree entin, ft pule, ulcer/gngrene. S ttticl nly Sperm n crreltin cefficient, w ue exme reltinhip tween ech vrible [11]. Crnbch lph cefficient clculte MDQ eterme relibily ternl cntency STATA. R ESULTS [11] ug tt pckge P ychmetric nly upprte r elibily vliy 41 em Hi q uetinnire three ubcle: Lerng e (α = 0.872), elf cre ctivie (α = 0.9613), elf cre prgrm (α = 0.9636). tet retet relibily tercl crreltin tfcry when ubmple 50 ptient t ete 4 week tervl. Pern crreltin cefficient fun ignificnt thir ubcle (p<0.0005). Out three ubcle elf cre ctivie elf cre prgrm fun gg prllel re epenent n ech r (p<0.05). Where firt lerng ib ete cn cnier epenent. T ble 1 Demgrphic & Clicl Dt C hrctertic N umr P ercentge S ex M le 12 24 F emle 38 76 T ype t retment O rl pill 45 90 I nul 05 10 O r cnin C ric ee 20 40 H ypertenin 40 80 Severe v in l 17 34 R enl ee 03 06 D ISCUSSION MDQ cnt three ectin. Sectin firt cnt thirteen quetin, ectin ecn cnt twelve quetin ectin thir cnt thirteen quetin. e three ectin cnt vriu em cncerng future uncertty, tretment, fmily cil reltinhip ttue wr e. Origl MDQ Englh lnguge ifficult cmmn mn type 2 e unert quetinnire i n Englh. Thu, MDQ trnlte Hi n ntinl lnguge Ini. culturl pttin MDQ ur tuy thu encmpe tw eentil tep, clue trnltin MDQ Hi lnguge keepg fe l gutic unimy evlutin pychmetric prpertie queti- nnire pychmetric vlin. A Ini hvg mre numr ic ptient, th MDQ Hi lnguge will S. S. P wr et.l, JPRCP 2011; 1( 3 ) 10

J urnl Phrmceuticl Reerch & Clicl Prctice, July- S ept 2011; ueful tuy ic p tient l cn ue clicl t ril clicin Ini. C ONCLUSION In chrnic cnin uch e, helth- relte quly (HR) n epecilly imprtnt utcme, givg ir lng nture nee ily elf- m ngement. Our tuy revel tht th Hi trnlte vle MDQ cn b e crprte ic ptient furr utily tuie. Furr reerch REFERE NCES 1. Mrth M. Funnell. Quly ul rpy type 2 e mellu. Excerpt Meic Inc, 2008: p. 31-36. 2. T lbt F, N uwen A, G gr J, G el M, A uet J. ement e- relte cgnive cil fcr: Multiimeninl De Quetinnire. B ehv Me, 1997 Jun; 20(3): p. 291-312. 3. Brly C, Hbk pychlgy e, Hrw Ac Pub, Swzerl: 1994: p. 65 87. 4. C DC. Prevlence bily ce h elth cnin U ne Stte, 1991 1992. M MWR 1994; 43: p. 730 7. 5. CDC. Chrnic Dee Preventin. Buren C hrnic Dee ir Rk Fcr Ntinl Stte Perpective. Atlnt, GA: D eprtment Helth Humn Service, 2002. 6. Segl L. imprtnce ptient empwerment helth ytem rem. Helth P licy. 1998; 44: p. 31 44. neee, e.g. regrg trnculturl ethnic pect, cmprg utcme ifferent tretment trtegie, i nclug e ffect tyle terventin. A CKNOWLEDGEMENT A uthr re thnkful Nuwen Arie givg permin ue q uetinnire. We wh expre ur grtue prticipnt wh generuly u. hre ir reflectin 7. Eyenbch G, Diepgen TL. rle e- helth cnumer helth mtic evience- b e ptient chice 21t century. Cl D erml 2001; 19: p.11 17. 8. Cile RC Jr. E- helth: reventg helthcre mtin ge. J Helthc Mng 2000; 45: p. 206 10. 9. Lffel, L.M., A. Cnnell, L. Vngne, A. Gel- Fbbri, A. Mnfiel, B.J. Anern. Generl q uly yuth type 1 e: reltinhip ptient mngement e- pecific fmily cnflict. De Cre, 2003. 26(11): p. 3067-73. 10. Cull A, Sprnger MAG, Bjrl K, Arnn NK, Wet K Btmley. EORTC Quly Life G rup Trnltin Prceure. EORTC Quly Life Grup Publictin, Bruel, April 2002: 2-930064-28-5. 11. Gill A, Jckn W. Reerch nure: meth terprettin. Philelphi, FA D v, 2002: p. 403. S. S. P wr et.l, JPRCP 2011; 1( 3 ) 11