DNA THE CODE OF LIFE 05 JULY 2014

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LIFE SIENES N THE OE OF LIFE 05 JULY 2014 Lesson escription In this lesson we nswer questions on: o N, RN and Protein synthesis o The processes of mitosis and meiosis o omparison of the processes of meiosis and mitosis o The importance of meiosis o bnormal meiosis occurs and its consequences Summary Test Yourself Select the most correct answer from the options given. Write down only the correct letter Question 1 Which of the following statements are characteristic of N? (i) (ii) (iii) (iv) ouble-stranded helix Sugar molecule is ribose Found in the nucleus onstant amount normally found in all the somatic cells of a particular species. (i), (ii) and (iii) only. (i), (ii) and (iv) only Page 1

. (i), (iii) and (iv) only LIFE SIENES. (i), (ii), (iii) and (iv) Question 2 The following data represents a small section of a sequence of nucleic acid bases taken from an animal cell: From this data it is reasonable to conclude that G U G U U. this portion of nucleic acid will code for a chain of eight amino acids.. the sequence given will be complementary to the sequence T G T G T T.. the nucleic acid shown contains the sugar ribose.. the nucleic acid shown is N. Question 3 The list below provides information relating to the replication of N: 1. omplementary nucleotides bind to each of the two strands. 2. Sugar phosphate bonds form between the nucleotides. 3. The newly formed N molecules are identical to each other. 4. fter unwinding, the N molecule forms two single strands. The correct order of these events as they occur in N replication is 1, 2, 3 and 4. 1, 2, 3 and 2. 4, 2, 1 and 3. 4, 1, 2 and 3. Question 4 In an investigation it was found that 10% of the bases in a molecule of N were thymine. What was the ratio of thymine to guanine in the same molecule? 1:2 1:3 1:1 1:4 Question 5 ring of bacterial N that is found in addition to the organism's main N is known as a protein plasmid genome triplet Page 2

Question 6 LIFE SIENES The relationship between nucleic acids and nucleotides is that... nucleotides are building blocks of nucleic acids. nucleic acids are building blocks of nucleotides. nucleotides are larger than nucleic acids. nucleic acids are found in the nucleus and nucleotides are found in the cytoplasm. Question 7 The structure of RN.. guanine pairs with thymine. guanine pairs with adenine. adenine pairs with thymine adenine pairs with uracil. Question 8 If one side of a N molecule contains the following sequence of nucleotides, GTG, the complementary sequence on the codon would be: TGG GTG UGG UUGG Question 9 The repeating units in both N and RN are called: nucleotides amino acids nucleic acids hydrogen bonds Question 10 Which of the following undergo meiosis? sperm cells haploid cells in the ovary liver cells diploid cells in the testes Question 11 Give the correct biological term for each of the following descriptions. Write only the term next to the question number 1. The two parts of a chromosome held together by a centromere 2. pair of chromosomes, one inherited from each parent, that have the same genes at the same loci 3. The point at which chromatids of homologous chromosomes cross over during meiosis Page 3

LIFE SIENES 4. The process by which the N molecule makes a copy of itself 5. The phase in meiosis where the N molecule makes a copy of itself 6. The phase in meiosis which results in the halving of the chromosome number 7. n arrangement of black bars representing N fragments that can be used to determine whether people are related Question 12 Indicate whether each of the statements in OLUMN I applies to only, only, both and or none of the items in OLUMN II. Write only, only, both and or none OLUMN I 1 hromosome condition of a cell that has a single set of chromosomes 2 auses of variation during meiosis OLUMN II : Haploid : iploid : Random fertilisation : Random mating 3 Increases variation in a species : loning : Mutation 4 iscovered the double helical structure of N : Francis rick : James Watson Question 13 The diagrams below show cells dividing during meiosis 1 2 3 4 5 E Page 4

LIFE SIENES 13.1 Give the names of the parts labelled to E respectively. (5) 13.2 Identify the phase represented in: a.) iagram 1 (1) b.) iagram 2 (1) 13.3 Write down the numbers of the diagrams in the correct sequence in which the phases occur. (3) 13.4 State TWO ways in which meiosis is important. (2) Question 1 Exam Questions (dapted from March 2014, Paper 1) pair of chromosomes, one inherited from each parent, that have the same genes at the same loci 1.1 Identify the parts labelled and. 1.2. State whether the phase of meiosis shown above is a part of Meiosis I or Meiosis II. 1.3. Give ONE visible reason for your answer to QUESTION 1.1. 1.4. nswer the following questions: (a) (b) How many chromosomes are present in the cell above? How many chromosomes will be present in each cell at the end of meiosis? 1.5. ould the cell represented in the diagram be that of a human? 1.6. Explain your answer to QUESTION 1.5. Page 5

Question 2 LIFE SIENES The diagram below shows the result of abnormal meiosis, starting with a cell showing chromosome pair 21. 2.1 Explain the number of chromosomes present in sperm R and sperm T. 2.2 How many copies of chromosome 21 would you expect in a normal gamete? 2.3 What genetic disorder will result if sperm U fertilises a normal ovum? 2.4 escribe TWO ways in which meiosis contributes to genetic variation. Question 3 The diagram below shows the structure of part of a N molecule. Study the diagram and answer the questions 3.1 Name the structures labelled,, and. (4) Page 6

LIFE SIENES 3.2 What are the components of a nucleotide? (3) 3.4 Explain how this molecule makes a copy of itself. (4) 3.5 Tabulate THREE differences between N and ribonucleic acid (RN). (7) Question 4 The diagram below shows the process of protein synthesis. 4.1 Identify the following: (a) (b) Molecule X Organelle Y 4.2 Identify the nitrogenous base labelled: (a) 1 (b) 3 4.3 escribe the role of N during transcription. 4.4 escribe the part of protein synthesis shown as process W, which occurs at organelle Y. 4.5 The table below shows the amino acids that correspond with different N codes. Write down the correct sequence of amino acids coded for by structure S in the diagram. Page 7

Question 5 LIFE SIENES (dapted from March 2014, Paper 1) Start with a cell containing FOUR chromosomes and describe LL the chromosomal changes that occur during meiosis, resulting in the formation of abnormal gametes due to non-disjunction in meiosis 1. ontent: (17) Synthesis: (3) (20) Page 8