DNA and GENETICS UNIT NOTES

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DNA and GENETICS UNIT NOTES NAME: DO NOT LOSE! 1 DNA - Deoxyribose Nucleic Acid Shape is called double DNA has the information for our cells to make. DNA through transcription makes m mrna through translation makes (ribosomes) Watson and Crick ( ) Discovered structure of DNA. Rosalind? Who is she?

Watson and Crick used her to create the double helix but never gave her credit. She died just before they won the Nobel Prize. Each unit of DNA called a of DNA consists of 3 parts. Phosphate A -carbon sugar (deoxyribose) A base attached to the sugar 2 There are different types of nucleotides found in DNA A is for G is for C is for T is for

3 A goes with T C goes with G WRONG! T C or G - A RNA - strand - Uracil replaces

4 NEW AREA OF FOCUS: CELL DIVISION Mitosis Cellular When one cell divides into Exact copy of the cells material is made.

Interphase Most of cell cycle ( %) Cell and develops (gets bigger) Chr not visible Nucleus intact DNA is 5 Prophase Chromatin draws together to create. Spindle fibers form. Prometaphase Prometaphase Nuclear envelope down. Centrosomes are positioned at poles of the cell. Spindle fibers attach to chromosome at the kinetochore.

Metaphase - Chromosomes line up on 6 Anaphase Chromosomes get split at The two identical copies get pulled Telophase Chromosomes reach poles. Nuclear membrane begins to. Cleavage furrow forms pinching cell into two. Chromosomes begin to.

Cytokinesis: Cell breaks into two (Cell Plate Visible in plants) 7 Prometaphase

Cancer is: Uncontrolled, unregulated cell and. Mitosis out of control. 8 A few things that may help you avoid cancer. Don t or chew Avoid exposure (skin cancer) Exercise daily Eat Don t drink excessive alcohol Avoid / energy exposure Avoid unprotected sex ( virus) Get regular checks up with your doctor What s in a cigarette?

Meiosis: Cell division that produces cells. 9 Prometaphase Meiosis involves Has cell divisions in meiosis, A in the amount of genetic material Results in the number of chromosomes Crossing-Over Law of segregation (Heredity), states that allele pairs or segregate

during gamete formation, and unite at fertilization. A gene can exist in more than one form. Organisms inherit alleles for each trait. When gametes are produced (by meiosis), allele pairs separate leaving each cell with a allele for each trait. Independent Assortment: Genes assort independently because they are located on chromosomes in gamete formation. 10

Meiosis involves. Sperm has chromosomes (haploid) Egg has chromosomes (haploid) When they meet you have 46 ( ) Crossing Over : Genetic segments of information are when the chromosomes are next to each other ( and creates millions of possibilities) Re of genetic information Produces four different germ (reproductive cells) 11 Genetics Large Paragraph (Has all of the key terms) Gregor M : The father of modern genetics. He counted his results and kept statistical notes, much like your science journal. The year was 1851, a young priest from Vienna studied mathematics and science at the university. Upon finishing, he went back to priesthood and tended a garden outside of the monastery. He worked with pea plants and became curious as to why some pea plants had different characteristics or ( ). Mendel seemed to notice that pea plants tended to pass traits from parents to offspring, which is called ( ). Mendel started doing experiments with ( ) plants, or plants that always produce offspring with the same trait as the parent. For example, short pea plants always

produce short offspring. Mendel then decided to cross short pea plants with tall pea plants. 12 An organism s ( ) is its physical appearance or its visible traits. An organism s ( ) is its genetic makeup, or allele combinations. From all of Mendel s results, he reasoned that individual factors must control the inheritance of traits in peas. Mendel knew that the female contributes one factor, while the male contributes the other factor in ( ). Today s scientists call the factors that control traits ( ). Scientists call the different forms of gene alleles. A dominant allele is one whose trait always shows up in the organism when the allele is present. A ( ) is

covered up when the dominant allele is with it. A ( ) has two different alleles. 13 Law of (Heredity), states that allele pairs separate or segregate during gamete formation, and randomly unite at fertilization. A can exist in more than one form. Organisms inherit alleles for each trait. When gametes are produced (by meiosis), allele pairs leaving each cell with a single allele for each trait. T = Dominant t = Recessive TT = Two dominant tt = Two recessive Tt = One dominant, one recessive P Square: A diagram that is used to predict the outcome of a particular cross

14 Genetics deals heavily with, or the likelihood that a particular event will occur. zygous- Has two identical alleles TT or tt zygous Dominant: All dominant zygous- Has two different alleles Tt Dihybrid Cross

Codominance or a relationship among alleles where alleles contribute to the phenotype of the heterozygote. 15

Incomplete Dominance: allele for a specific trait is not completely dominant over the other. 16 New Area of Focus: BIO-ETHICS Bio-Ethics: The study of ethical issues raised by the developments in life science. Stem cells: Cells that have the remarkable potential to develop into many different cell in the body.

17 Cloning: A method of reproduction used to copy a cell or an individual (producing a clone) from their. Copyright 2010 Ryan P. Murphy