WhatsNext. Ready. Set. Pipette! New Innovative solutions for 384-well pipetting. Issue 1/ st March 30 th June 2019.

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Issue /209 st March 30 th June 209 WhatsNext Ready. Set. Pipette! New Innovative solutions for 384-well pipetting Product information Contest 5 ml consumables Page 4 New CellXpert CO 2 Incubator Page 5 Win a friend for life! Page 0

New Products New Products More Volumes. More Flexibility. Additional volume variants Eppendorf Research plus and Eppendorf Xplorer plus All the benefits you already know now exactly in the volume you were always looking for. Product Eppendorf Research plus Eppendorf Xplorer / Xplorer plus Eppendorf Xplorer / Xplorer plus Eppendorf Xplorer / Xplorer plus 6 and Wells in Just One Step! Do you work with 384-well plates and strive for more efficient pipetting methods? Your worries are over! The new 6- and -channel pipettes plus pipette tips from Eppendorf for ergonomic and safe working with 384-well plates. From reagent reservoir to 384-well plate 2 3 From 384to 384-well plate From 384-well plate to agarose gel Good to know Pipetting facts and much more: www.eppendorf.com/handling-solutions Safety and reproducibility The extraordinary coaxiality of ept.i.p.s. 384 and their extremely fine tip shape ensure safe plate maneuvering and liquid transfer. Start 6/ reactions simultaneously. Explore new volumes: Buy any of the new volume Eppendorf Xplorer plus electronic pipettes, with programming functions, and receive a free charger stand. Time-saving Alternate well pipetting with 8 or 2-channel pipettes is a thing of the past. Fill a complete 384-well plate in just one minute. Receive 5 trays of ept.i.p.s. for FREE with Eppendorf Research plus or Eppendorf Xplorer plus Starter Pack (includes reusable box). No of Channels 6- or -channel 6- or -channel Volume 20 μl 5 00 μl Available as Eppendorf Research plus or Eppendorf Xplorer plus www.eppendorf.com/whatsnext-xplorer-plus Our virtual Pipetting Ninja has been helping you during the past two years to fine-tune your pipetting techniques. Order your starter pack online and receive additional 384-well sample plates for free. www.eppendorf.com/whatsnext-starter-pack The perfect fit with innovative ept.i.p.s. 384 New Eppendorf ept.i.p.s. 384 now with elastic forming grooves. These allow the tips to stretch as much as necessary to enable a perfect seal. > Outstanding and reliable tip fit and tightness > Reduced tip attachment and ejection forces 2 Colour code Red Light gray Yellow Red Eppendorf Research plus 8 and 2-channel 0.2-.2 ml coming soon Pipetting into 384-well plates made easy Volume 0.25-2.5 ml -20 µl 0-200 µl 0.25-2.5 ml Tell us how you have personally improved your pipetting techniques and turned into a real Pipetting Ninja. Our Pipetting Ninja has now been brought to life and would like to go on an adventurous trip. The first 00 customers who share their story will be awarded a Pipetting Ninja trophy. Details on our challenge: www.eppendorf.com/ninja-challenge 3

Worth Knowing Is it Really DNA You Are Measuring? Most of the time you have one chance to get your experiment right. Samples are precious and unique. So you need to ensure the plastics you are using don t interfere with your samples. Are you aware of the many substances that leach from plastic consumables? The most critical leaching additives are > Slip agents > Biocides > Plasticizers Not all consumables are the same False positives, wrong appreciation of biological results, waste of time and costs, and unreliable measurement are some of the outcomes. Unfortunately, leachables are easily detected in UVabsorbent measurements, interfering with spectroscopic analyses such as those employed during DNA quantifications. Eppendorf is committed to manufacturing only the highest quality of plastic consumables without the use of slip agents, plasticizers or biocides, giving you peace of mind about your results. View more information at: www.eppendorf.com/eppendorf-quality Find our General Quality Certificate for ept.i.p.s., Eppendorf Tubes, Eppendorf Plates and UVette here: For the Real CellXpert The new CellXpert CO 2 Incubators make your culturing more efficient, safe, and comfortable. Long-lasting quality made in Germany. Full control and easy documentation > Quick recovery times < 5 min. without regulation overshoot > Multiple integrated temperature sensors for optimized homogeneity > Connect your lab and remotely monitor all your devices within the new VisioNize connected lab system More pictures and all smart details: www.eppendorf.com/cellxpert The perfect match: Eppendorf Cell Culture Consumables with updated 209 prices now available in our eshop. Order anytime, /7: www.eppendorf.com/ccic Save 5 % Eppendorf Tubes 5.0 ml Our CellXpert special Eppendorf Tubes 5.0 ml with snap cap or screw cap - the missing link for volumes smaller than 5 ml but larger than 2 ml. See it for yourself. Take advantage of 5% OFF for a limited time period only on a selection of tubes. www.eppendorf.com/whatsnext-tubes5ml Free stacking kit with 2 CellXpert CO 2 Incubators (upper and lower frame). Plus an extended 5-year warranty for your peace of mind (automatically included for all CellXpert Incubators ordered in 209). Visit our website: www.eppendorf.com/whatsnext-cellxpert-special 4 5

What Makes a Green ULT Freezer? Many people focus on energy consumption when considering how sustainable a ULT freezer is, however, the story is far more complex than that! Many other factors can affect how green a product is. Eppendorf freezers have a reputation for lasting longer and performing better. The high manufacturing quality of Eppendorf freezers translates to lasting peace of mind for you. Did you know Eppendorf manufacture their ULT freezers in Europe? Less shipping means less CO 2! A Silent Companion: New Centrifuge 5425 Centrifuge 5425 is the successor of the legendary lab standard Centrifuge 54. This -place centrifuge has been engineered to be extremely quiet. Short runs up to 2 minutes are whisper quiet at an average of 45 db(a). This is sufficient for centrifugation steps of most routinely used DNA/RNA purification kits. During longer runs the cooling fan works at full capacity to dissipate the heat for the remainder of the run. Even so the Centrifuge 5425 is still the quietest non-refrigerated microcentrifuge on the market with a noise level below 5 db(a). Find out more about the Eppendorf drive to reduce our environmental impact at: www.eppendorf.com/sustainability Eppendorf has led the way with high-performance, energy-efficient freezers, such as the new CryoCube F740hi upright 700 L freezer. This approach combines green manufacturing techniques with an ongoing drive to reduce our environmental footprint. Eppendorf freezers: protecting both your samples and the environment! Improve your sample management with Eppendorf ULT freezers! Effective sample management can also help improve your freezer efficiency: > Locate your sample quickly > Reduce the time the door stays open > Significantly reduce the energy required to return your ULT to -80 o C What s new? Low noise operation Quietest non-refrigerated microcentrifuge on the market for stress-free work. Extended rotor program Comprehensive range of 6 rotors for all your applications. Uncompromised safety Aerosol-tight Eppendorf QuickLock lids for simple and safe handling.,000 Free Freezer Racking More information at www.eppendorf.com/centrifuge-5425 To help you, manage your samples, Eppendorf will give you 000 of Eppendorf freezer racking free of charge with every purchase of a green Eppendorf ULT freezer F740hi during the WhatsNext promotion. Contact your Eppendorf green team to arrange a quotation now! www.eppendorf.com/whatsnext-freezer For a limited time only! Take advantage of this great bundle offer. Centrifuge 5425 non-refrigerated, with rotary knobs + x Rotor FA-x2, aerosol-tight rotor with lid for x Eppendorf Safe-Lock Tubes.5 ml or 2.0 ml + pack of,000 Safe-Lock Tubes,.5 ml, colorless www.eppendorf.com/whatsnext-centrifuge-5425 6 7

A Versatile Companion: Centrifuge 590 R Tired of changing rotors? Centrifuge 590 R offers its new swing-bucket rotor S-4xUniversal with great versatility thanks to its universal adapters which accommodate bottles, plates, and more 5/50 ml conical tubes than the standard 3 liter multipurpose centrifuge. Centrifuge 590 R convinces through versatility and capacity, complete with swing-bucket and fixed-angle rotors. It takes care of your sensitive cells Hardware and software features manage energy efficiency and sample protection. This saves energy and time. Innovative safety features Automatic rotor recognition and built-in imbalance sensors protect the centrifuge, your sample and most importantly you. Excellent user convenience Centrifuge 590 R features a low noise level and a softtouch lid for stress-free instrument closing. Improve Your Flexibility The new SmartExtender is a comfortable incubation accessory that is easy to use as an add-on to your existing SmartBlocks and the Eppendorf ThermoMixer C. > Up to 2 vessels (.5 ml) for higher throughput and higher flexibility > Independent heating function for a second temperature > Parallel usage of SmartBlock and SmartExtender Using different vessel sizes within your workflow? Flexibility has never been this easy. Eppendorf offers a broad range of 3 SmartBlocks for tubes from 0.2 ml to 50 ml in volumes as well as plates (MTP, DWP, and PCR plates 96 / 384). All SmartBlocks are equipped with the Eppendorf QuickRelease system that makes the block exchange quick and easy no tools are necessary. www.eppendorf.com/smartblocks www.eppendorf.com/centrifuge-590r Eppendorf ThermoMixer bundle save 25 % Cell Culture Bundle Centrifuge 590 R, refrigerated with Rotor S-4xUniversal, including universal buckets and adapters for tubes, plates, and bottles Eppendorf ThermoMixer C + Eppendorf SmartBlock.5 ml + SmartExtender www.eppendorf.com/whatsnext-thermomixer + pack Eppendorf Conical Tubes 50 ml, in polypropylene racks (300 tubes) + pack Eppendorf Conical Tubes 5 ml, in polypropylene racks (500 tubes) + pack Cell Culture Plates, 96-well, non-treated (80 plates) www.eppendorf.com/whatsnext-centrifuge-590r Want to prevent condensation? Watch the video on how you can prevent condensation by using the Eppendorf ThermoTop with special condens.protect technology. For more information visit www.eppendorf.com/thermotop 8 9

Wall of Fame Providing Peace of Mind! Experience the world of Eppendorf automated pipetting systems. They have been designed to bring value to your daily work life by providing high efficiency, ease of use, peace of mind, and versatility. They are Friends for Life! Ease of use epmotion 96 is your best friend in replication of microtiter plates, cell-based assays, ELISA, magnetic bead-based applications, handling of 96/384 well plates, etc. Leave the tedious pipetting to epmotion 96. High efficiency epmotion 5070 is designed to be intuitive, selfexplanatory and easy to use. PCR and qpcr set-up was never easier. Minimize reagent usage, reduce errors, and improve results. Serial dilutions, re-formatting, and normalization made easy. Peace of mind epmotion 5073 is an affordable solution to make NGS library preparation easier than ever before, in offering you a walk away liquid handling solution, allowing you to focus on more important tasks. Versatility epmotion 5075 brings you one step ahead in your daily work life. It offers you fully automated solutions for almost all existing applications in your lab. Stay ahead! Win a friend for life!* Win a brand-new epmotion 5070 We are looking for the oldest automated pipetting system in life science across Europe. Take a picture of your old automated pipetting system (all brands), send it to WhatsNext@eppendorf.com and state for which applications you use it. *Competition closes 30th June 209. Participation conditions can be found at: www.eppendorf.com/friend_for_life_contest 0 Service from the experts! Did you know that the success story of Eppendorf began way back in 945 as a small medical instrument repair workshop on the grounds of the University Hospital Eppendorf in Hamburg, Germany? Today, more than seven decades later, our highly qualified team of service professionals supports customers around the globe. Our vision: we strive to make our customers feel confident and proud when they use our products and services Compliance when you need it! Our Installation & Operational Qualification services are designed to support compliance with your laboratory guidelines and with manufacturers specifications. Regular verification and adjustment services are highly recommended, especially where reaching defined temperatures within an instrument is crucial for correct and reproducible results. Our services include: > On-site preventive maintenance > Installation and certification > Calibration and verification > Repair and breakdown > Technical support > Software updates» Eppendorf epservices personnel are specialists with technical expertise, but also partners who listen and enable us, year after year, to meet the requirements of accreditation. «Christophe Lehobey, Biomedical Maintenance Manager, Institut Curie, France. Get expert care for your total peace of mind! Visit www.eppendorf.com/epservices

Contest Fancy a Challenge? Eppendorf word search puzzle Are you a word search master? We have hidden 7 words inside of our puzzle. They can be found forwards, backwards, horizontally, vertically or diagonally. Find at least 5 words to qualify for entry in the competition. Please visit www.eppendorf.com/whatsnext-competition and mark all the words that you can find inside the box. Have fun and win some great prizes! st Prize 2nd Prize 3rd Prize 400 eshop voucher 300 eshop voucher Free Eppendorf Research plus single channel pipette of your choice What do you think about WhatsNext? We would like to receive your feedback www.eppendorf.com/whatsnext-feedback Terms & Conditions: To enter the competition please visit www.eppendorf.com/whatsnext-competition. The winners will be announced by 5 th July 209. One entry per participant. Winners are required to find 5 words correctly and will be selected randomly from all correct answers. The prizes can t be exchanged for cash or its equivalent value. Contact us: www.eppendorf.com/contact All prices are in Euro excl. VAT and valid until 3.2.209. All special offers are valid until 30.06.209 and cannot be combined with other discounts from Eppendorf. No cash redemption. Errors and mistakes reserved. Eppendorf, the Eppendorf Brand Design, CellXpert, CryoCube, condens.protect, epmotion, ept.i.p.s., epservices for premium performance, Eppendorf Plates, Eppendorf Quick- Lock, Eppendorf Research, Eppendorf ThermoTop, Eppendorf ThermoMixer, Eppendorf Tubes, Eppendorf Xplorer, the epservices logo, UVette and VisioNize are registered trademarks of Eppendorf AG, Germany. Eppendorf Quality, Eppendorf Quick Release and Eppendorf SmartBlock are trademarks of Eppendorf AG, Germany. U. S. Design Patents are listed on www.eppendorf.com/ip. All rights reserved, including graphics and images. Copyright 209 by Eppendorf AG. Carbon neutrally printed in Germany.