Feasibility study of TULIP: a TUrning LInac for Protontherapy ICTR-PHE 2012 Conference 28.02.2012 A. Degiovanni U. Amaldi, M. Garlasché, K. Kraus, P. Magagnin, U. Oelfke, P. Posocco, P. Riboni, V. Rizzoglio
TULIP: a Single Room Facility project Why single room facilities? Proton therapy beneficial to at least 12% of X-ray patients (ENLIGHT studies outcome) ~ 2.400 patients/year every 10'000'000 people 1 proton room every 1.5 Milion inhabitants Advantages Spread the investement cost Hospital based protontherapy (not dedicated centres) Technical challenges Size and cost of the machine Dose delivery modalities Treatment time 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 2
A cyclinac based solution TULIP = TUrning LInac for Protontherapy C-band linac Section 1 C-band linac Section 2 cyclotron Line with 2% momentum acceptance RF rotating joints Beam dose delivery RF Power sources Mechanical structure 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 3
The CYCLINAC timeline 1993: first Cyclinac proposal 2003: test on LIBO-62 MeV (TERA-CERN-INFN) [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131] 2007: first CABOTO design * See abs. #227 by S. Verdú Andrés 2010: CABOTO-C design (*) 11.2010: LIGHT 1st UNIT inaugurated by CERN DG Prof. R. Heuer (courtesy of ADAM SA.) 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 4
Electric field distribution ib ti (HFSS) The linac and RF system coupl. cell on side acc. cell on axis excited cavity acc. tanks un-excited cavity TANK space for quadrupoles RF cavities in π/2 mode Accelerating TANKS Acc. units with space for PMQs H 11 polarizer (Igor Syratchev, CERN) linear polarization circular polarization 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 5
The CYCLINAC timeline 1993: first Cyclinac proposal 2003: test on LIBO-62 MeV (TERA-CERN-INFN) 2007: first CABOTO design * See abs. #227 by S. Verdú Andrés 2010: CABOTO-C design (*) E 0 = 15 MV/m [U. Amaldi, S. Braccini and P. Puggioni, RAST Vol 2 (2009) 111-131] E 0 = 16 MV/m 11.2010: LIGHT 1st UNIT inaugurated by CERN DG Prof. R. Heuer (courtesy of ADAM SA.) 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 6
The choice of the frequency TULIP project requires shorter linacs Higher gradients are needed (~35 MV/m) Reliability in terms of BDR High gradient tests (S- and C- band) in collaboration with CLIC see poster #203 (Cyclinac group) Size of RF rotating joints for power transmission Power source availability C- band : 5.712 GHz 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 7
TULIP preliminary design @5.7 GHz (C-band) from 35 to 210 MeV Quantity [unit] Section 1 Section 2 Output energy [MeV] 80 210 Total length [m] 3.9 5.9 Avg. E 0 [MV/m] 20-24 32-38 Max. E SURFACE [MV/m] 150 170 Number of units 1 (4) 7 Peak Power [MW] 25 84 Repetition rate [Hz] 200 200 Pulse length [μs] 2.5 2.5 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 8
Fast active energy variation E) (E) / N(E dn( Energy [MeV] 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 9
Fast active energy variation Active energy variation in the range 80-210 MeV Energy spread within 2 mm distal fall-off Active spot scanning with tumour multipainting 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 10
TULIP beam transfer line With Δp/p = ±2% ΔR/R = ± 7% For R = 30 cm ΔR = ± 2.1 cm R R E 1.8 3. 5 E p p 30.5 29.4 cm 31.7 28.2 cm cm 32.9 cm cm 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 11
Supporting structure C-band linac Section I [kg] Section II [kg] Linac 340 460 Beam Structure 3400 4800 Ancillaries 640 860 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 12
TULIP Mechanical Design Bearings Rot. axis Actuators 1 2 3 Total estimated 60 weight [tons] Max ang acceleration 0.5 [rad/s 2 ] Max rotation 1.5 speed* [rpm] * derived from norm EN 60601 and max vel considerations 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 13
Novel study of dynamic dose delivery simulation of dynamic delivery via computer software based on treatment plan data for a static dose delivery dynamic parameters (repetition rate, v Gantry, v Couch ) TPS: Calculation of static plan Plan data: D ij matrices Spot positions Spot weights Tulip machine parameters: Gantry speed Repetition rate Couch speed Number of protons Dynamic dose calculation l Dose distribution more information: Poster 156 by Kim Kraus (DKFZ, Heidelberg) 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 14
Novel study of dynamic dose delivery dynamic dose delivery to a cylindrical target volume different combinations of dynamic parameters the higher the gantry speed the higher must be the repetition rate to deliver all spots D Diff =D dyn (f= 100Hz, v Gantry = 1 /s) - D static Difference dose distribution : Good agreement of the dynamic and static dose distributions within the target! 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 15
Summary First design in C-band for a single room facility: Linac and RF design Mechanical design Novel dose delivery Cyclinac concept Future developments: - Optimization of Section 1 - Final mechanical spec. Compact beam line TULIP New dose delivery e Combine acceleration and gantry flexibility with active energy variation New mechanical design 28.02.2012 ICTR-PHE 2012 - A. Degiovanni 16