Mohammed Mahmoud H Ghoneim Ph.D. Address: E-Mail: Researchgate: Riyadh, Saudi Arabia mghoneim@mcst.edu.sa https://www.researchgate.net/profile/mohammed_ghoneim Education 2014 Ph.D. Degree in Pharmaceutical Science Thesis title, Isolation and Structure Elucidation of Bioactive Compounds with Cytotoxic Activity from Some Egyptian Plants Belonging to Family Liliaceae Through a visiting scholarship system between the University of Al- Azhar,Cairo, Egypt and University of Mississippi and National Center for Natural Products Resaerch, MS 38677, USA (2011-2014) 2008 Master Degree in pharmaceutical Sciences (Pharmacognosy) Thesis title Phytochemical and Biological Study of Certain Justicia Species Cultivated in Egypt Faculty of Pharmacy, University of Al-Azhar, Egypt. 2002 B. Pharm. Sci., Faculty of Pharmacy Faculty of Pharmacy, University of Al-Azhar, Egypt (Grade: Excellent with Honor) Current Employment 2016-till now Assistant to Head of College of Pharmacy Al Maarefa Colleges for Science and Technology; Riyadh; KSA 2015-till now Assistant Professor of Natural Products and Phytochemistry Al Maarefa Colleges for Science and Technology; Riyadh; KSA Work Experience 2014-2015 Assistant Professor of Natural Products and Phytochemistry Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt 2011-2014 Visiting scientist NCNPR, School of Pharmacy, University of Mississippi, MS, 38677 USA. 2008-2011 Assistant Lecturer of Natural Products and Phytochemistry Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. 1
2003-2008 Teaching Assistant of Natural Products and Phytochemistry Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. Scientific Activities Teaching Experiences: Advanced training programs Participation 1. Teaching Natural Products courses for pharm-d students and bridging Program (including: Preparation of course portfolio, course reports and syllabus) in Al Maarefa Collage for Science and Technology; Riyadh; KSA, academic year 2015-until now. 2. Supervision and participation in the practical courses of Natural Products for preparatory, first and second year pharmacy students inal-azhar University, Cairo, Egypt. 3. Supervision and participation in the practical courses Natural Products for third and fourth years for pharmacy students in Al-Azhar University. 4. Participation in the theoretical courses Pharmacognosy I and II courses for pharmacy students, Al-Azhar University, Cairo, Egypt. 5. Head of the quality unit in the Pharmacognosy Department, Al-Azhar University, Cairo, Egypt. 6. Member of Quality Assurance Unit and preparation of Course portfolio, course reports and specifications) Al Maarefa Collage for Science and Technology 1. Effective presenting skills 2014 Cairo, Egypt 2. Examination preparing skills 2014 Cairo, Egypt 3. Course mapping and Course specification 2015 Cairo, Egypt 4. Self-assessment training course 2015 Cairo, Egypt Administrative and scientific committees: 1. Taking care of pharmacy college students both academically and administratively, also supervises the academic staff in the department and handles the daily running of college of pharmacy. 2. Member of the Parmacognosy departmental council. 3. Member of the College council. 4. Member of the research laboratory development committee. 5. Head of the academic advising committee. 6. Member in Curriculum Development Committee. Highlights of Skills and expertise: Well proven practical skills in planning and executing isolation and structure elucidation of isolated metabolites from Natural Sources (marine, plants, fungi) Expertise in chromatographic techniques such as HPLC (High Performance Liquid Chromatography, analytical and preparative), LCMS, Centrifugal partition chromatography, VLC, SPE and other chromatographic Techniques for the isolation of pure bioactive secondary metabolites. Expertise in the growing of terrestrial fungi using liquid and solid media. Expertise in NMR (Nuclear Magnetic Resonance, Varian, Bruker and Jeol) data interpretation as well as acquiring the data. Ability to collect data and interpret MS (Mass spectrometry) and NMR spectra for structure elucidation of complex biological molecules and 2
identification of natural products. Recording and analyzing data in computerized formats and executing spectroscopic (NMR and MS) analysis. Good written and communication skills and the ability to work well in a collaborative/ industrial environments. Expertise in Natural Product Isolation, Extraction, Flavonoids, NMR Structure Elucidation, Natural Product Research, Bioactivity, Phytochemicals, Chromatography, Phytochemical Purification, Antibacterial Activity, Natural Chemistry, Bioactive Compounds, Natural Drugs, Novel Antibacterial Agents From Plants, Phenolic Compounds, Secondary Metabolites, Pharmacognosy, ECD, HPLC-ECD, Natural Compounds, 2D- NMR, Docking and HPLC-DAD. Publications : 1. Mohammed M Ghoneim: Synthesis and Anticancer Studies of Novel N- Benzyl pyridazinone Derivatives. Letters in Drug Design & Discovery 02/2017; 14(12)., DOI:10.2174/1570180814666170223111312. 2. Ehab M Mostafa, Nevein M Abdelhady, Mohammed M Ghoneim, Atef A El-Hela: PHYTOCHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITES OF THYMUS DECUSSATUS BENTH. GROWING IN EGYPT. DOI: 10.20959/wjpr2016-12-7436. 3. Mohammed M Ghoneim: HPTLC Fingerprint Profile of Triterpenes of Lamium amplexicaule Benth. and Ajuga iva L. (Lamiaceae) Monitored with Screening of their Anti-inflammatory Effect. Journal of Pharmacognosy and Phytochemistry 2016; 5(6): 176-181. 4. Mohammed M Ghoneim: Cytotoxic, Antimicrobial and Antiviral Evaluation of the aerial parts of Sorghum virgatum Hack Journal of Biomedical and Pharmaceutical Research 3, no. 6 (2015). 5. Ahmed Metwaly, Mohammed M Ghoneim, Arafa Musa: Two New Antileishmanial Diketopiperazine Alkaloids from the Endophytic Fungus Trichosporum sp, Der Pharma Chemica, 2015, 7(11):322-327. 6. Mohamed A Ibrahim, Ahmed H Elmenoufy, Mohamed Elagawany, Mohammed M Ghoneim, Alaa Moawad: " Pyridopyridazine " : A Versatile Nucleus in Pharmaceutical Field. Journal of Biosciences and Medicines 10/2015; 3(10):59-66. DOI:10.4236/jbm.2015.310008. 7. Saleh, Mostafa, Mohammed M Ghoneim, Atef El-Hela, and Saeid Kottb. "BIOLOGICALLY ACTIVE SECONDARY METABOLITES FROM KALANCHOE TOMENTOSA." Journal of Biomedical and Pharmaceutical Research 3, no. 6 (2015). 8. Mohammed M. Ghoneim, Khaled M. Elokely, Atef A. El-Hela, Abd ElsalamI. Mohammad, Melissa Jacob, Mohamed Radwan, Stephen J. Cutler, Robert J. Doerksen, SamirA. Ross: Asphodosides A-E, Anti-MRSA Metabolites from Asphodelus microcarpus. Phytochemistry, 105, 79-84 (2014). 3
9. Mohammed M. Ghoneim, Khaled M. Elokely, Atef A. El-Hela, Abd ElsalamI. Mohammad, Melissa Jacob, Stephen J. Cutler, Robert J. Doerksen, SamirA. Ross: Isolation and characterization of new secondary metabolites from Asphodelus microcarpus. Medicinal Chemistry Research, 23 (7), 3510-3515 (2014). 10. Petra Hřibová, Elian Khazneh, Milan Zemlička, Emil Svajdlenka, Mohammed M Ghoneim, Khaled M Elokely, Samir A Ross: Antiurease activity of plants growing in the Czech Republic. Natural product research, 28 (12) (2014). 11. Mohammed M Ghoneim, Guoyi Ma, Atef A El-Hela, Abd-Elsalam I Mohammad, Saeid Kottob, Sayed El-Ghaly, Stephen J Cutler, Samir A Ross: Biologically active secondary metabolites from Asphodelus microcarpus.. Natural product communications, 8(8):1117-1119 (2013). 12. Mohamed, G. A., Ibrahim, S. R., Abdelkader, M. S., Al-Musayeib, N. M., Mohammed M Ghoneim & Ross, S. A. Zeaoxazolinone, a new antifungal. 2014 Research, agent from Zea mays roots. Medicinal Chemistry 13. Mohammed M Ghoneim, El-Hela, A. A., Mohammad, A. I., Kottb, S., Cutler, S. J., & Ross, S. A. Isolation and Structural Elucidation of New Biologically Active Secondary Metabolites from Asphodelus microcarpus.. 2013 Medica, 79, Planta 14. Mohammed M Ghoneim, El-Hela, A. A., Mohammad, A. E. I., Cutler, S. J., & Ross, S. A. Biologically Active Phenolic Metabolites from Asphodelus. PN31 microcarpus.planta Medica, 79(10), 15. Mohammed M Ghoneim, Ma, G., El-Hela, A. A., Mohammad, A. E. I., Cutler, S. J., & Ross, S. A. Antileukemic Anthraquinones from Asphodelus. PN17 microcarpus.planta Medica, 79(10), 16. Ross, S. A., Mohammed M Ghoneim, El-Hela, A. A., Mohammad, A. E. I., & Cutler, S. J. (2012, November). BIOLOGICAL ACTIVE SECONDARY METABOLITES FROM ASPHODELUS MICROCARPUS SALZM. ET VIVI. PHARMACEUTICAL BIOLOGY (Vol. 50, No. 11, pp. 1369-1369). 17. Khaled M. Elokely, Mohammed M. Ghoneim, SamirA. Ross, Robert J. Doerksen: Calculations on novel nucleus identified as (1R) 3, 10-dimethoxy- 5-methyl-1H-1,4-epoxybenzo[h]isochromene, Journal of Organic Chemistry, 7/2014 (submitted). 18. Mohammed M Ghoneim, Ma, G., El-Hela, A. A., Mohammad, A. E. I., Cutler, S. J., & Ross, S. A. New anthraquinones with in vitro binding affinity for cannabinoid receptors from Asphodelus microcarpus. Planta Medica, 80. PN32,(10) 19. Mohammed M Ghoneim, Ma, G., El-Hela, A. A., Mohammad, A. E. I., Cutler, S. J., & Ross, S. A. Computationally assisted assignment of highly. PN31 strained isochromene nucleus. Planta Medica, 80 (10), 4
Conferences: 1. 11th Annual Oxford International Conference on the Science of Botanicals (ICSB), Oxford, Mississippi, USA, April 16th 19th (2012). 2. 12Th Annual Oxford International Conference On the Science of Botanicals (ICSB), April 15-18, 2013, Oxford, MS, USA. 3. Phytochemical Society of North America 51st Annual Meeting (which was held on The University of Western Ontarion, London, ON, Canada). 4. The American Chemical Society, Ole Miss local section, 16th Annual poster session, which will presented at the University of Mississippi on November 8th, 2012. 5. The American Chemical Society, Ole Miss local section, 17th Annual poster session, which will presented at the University of Mississippi on November 10th, 2013. 6. The 5th Al-Azhar International Conference for Pharmaceutical and Biological Sciences, September 2008. 7. 54th Annual meeting of the American Society of Pharmacognosy (ASP), July 13th- July 17th, (2013), St. Louis, Mo, USA. Awards: Scholarship from the Egyptian Government under the supervision of Prof. Samir A. Ross, professor at University of Mississippi and National Center for Natural Products Resaerch, MS 38677, USA (2012-2014).. Memberships: membership at the following societies: 1. American chemical society (ACS) 2. American Society of Pharmacognosy (ASP) References Available Upon Request 5