Self-similar solutions to a parabolic system modelling chemotaxis

Similar documents
Exclusion of boundary blowup for 2D chemotaxis system with Dirichlet boundary condition for the Poisson part

EXISTENCE OF MULTIPLE SOLUTIONS FOR A NONLINEARLY PERTURBED ELLIPTIC PARABOLIC SYSTEM IN R 2

Point vortex mean field theories multi-intensities and kinetic model

On semilinear elliptic equations with nonlocal nonlinearity

Global unbounded solutions of the Fujita equation in the intermediate range

Non-homogeneous semilinear elliptic equations involving critical Sobolev exponent

A Semilinear Elliptic Problem with Neumann Condition on the Boundary

Finite-Time Blowup in a Supercritical Quasilinear Parabolic-Parabolic Keller-Segel System in Dimension 2

Note on the Chen-Lin Result with the Li-Zhang Method

SYMMETRY RESULTS FOR PERTURBED PROBLEMS AND RELATED QUESTIONS. Massimo Grosi Filomena Pacella S. L. Yadava. 1. Introduction

Aggregation vs. global diffusive behavior in the higher-dimensional Keller-Segel model

Radial Symmetry of Minimizers for Some Translation and Rotation Invariant Functionals

Journal of Differential Equations

Citation 数理解析研究所講究録 (2000), 1123:

A DEGREE THEORY FRAMEWORK FOR SEMILINEAR ELLIPTIC SYSTEMS

arxiv: v1 [math.ap] 4 Nov 2013

Pattern Formation in Chemotaxis

I Results in Mathematics

Global Existence for a Parabolic Chemotaxis Model with Prevention of Overcrowding

Free energy estimates for the two-dimensional Keller-Segel model

Author(s) Huang, Feimin; Matsumura, Akitaka; Citation Osaka Journal of Mathematics. 41(1)

2 JUNCHENG WEI Lin, Ni and Takagi rst in [11] established the existence of leastenergy solutions and Ni and Takagi in [13] and [14] showed that for su

ILL-POSEDNESS ISSUE FOR THE DRIFT DIFFUSION SYSTEM IN THE HOMOGENEOUS BESOV SPACES

ON THE GLOBAL EXISTENCE OF A CROSS-DIFFUSION SYSTEM. Yuan Lou. Wei-Ming Ni. Yaping Wu

Theory and its related Fields) Citation 数理解析研究所講究録 (2009), 1669:

BLOWUP THEORY FOR THE CRITICAL NONLINEAR SCHRÖDINGER EQUATIONS REVISITED

arxiv: v1 [math.ap] 24 Jun 2017

DETERMINATION OF THE BLOW-UP RATE FOR THE SEMILINEAR WAVE EQUATION

arxiv: v2 [math.ap] 17 Oct 2015

Bounds for nonlinear eigenvalue problems

Report on the chemotaxis-fluid systems

A one-dimensional nonlinear degenerate elliptic equation

SYMMETRY OF POSITIVE SOLUTIONS OF SOME NONLINEAR EQUATIONS. M. Grossi S. Kesavan F. Pacella M. Ramaswamy. 1. Introduction

OPTIMAL CONTROL FOR A PARABOLIC SYSTEM MODELLING CHEMOTAXIS

A RIEMANN PROBLEM FOR THE ISENTROPIC GAS DYNAMICS EQUATIONS

Local mountain-pass for a class of elliptic problems in R N involving critical growth

On Global Minimizers for a Variational Problem with non-local effect related to micro-phase separation

THE HOT SPOTS CONJECTURE FOR NEARLY CIRCULAR PLANAR CONVEX DOMAINS

Asymptotic Expansion. of Solution to the Nernst Planck Drift Diffusion Equation (1.1) 1. Introduction

SIMULTANEOUS AND NON-SIMULTANEOUS BLOW-UP AND UNIFORM BLOW-UP PROFILES FOR REACTION-DIFFUSION SYSTEM

Symmetry of entire solutions for a class of semilinear elliptic equations

Recent developments in elliptic partial differential equations of Monge Ampère type

Yoshiyuki Kagei. $\partial_{\overline{t}}\tilde{\rho}+div(\overline{\rho v})=0$, (1.1)

Non-radial solutions to a bi-harmonic equation with negative exponent

Mathematical analysis of tumour invasion model with proliferation and re-establishment

Classification of Solutions for an Integral Equation

EXISTENCE AND NONEXISTENCE OF ENTIRE SOLUTIONS TO THE LOGISTIC DIFFERENTIAL EQUATION

1 Discrete Morse semfflows

Recent results and open problems on parabolic equations with gradient nonlinearities

Liouville Theorems for Integral Systems Related to Fractional Lane-Emden Systems in R N +

Asymptotic behavior of threshold and sub-threshold solutions of a semilinear heat equation

THE SET OF CONCENTRATION FOR SOME HYPERBOLIC MODELS OF CHEMOTAXIS

Various behaviors of solutions for a semilinear heat equation after blowup

Breakdown of Pattern Formation in Activator-Inhibitor Systems and Unfolding of a Singular Equilibrium

A Caffarelli-Kohn-Nirenberg type inequality with variable exponent and applications to PDE s

ON MIXED BOUNDARY VALUE PROBLEMS FOR PARABOLIC EQUATIONS IN SINGULAR DOMAINS

COINCIDENCE SETS IN THE OBSTACLE PROBLEM FOR THE p-harmonic OPERATOR

A LIOUVILLE THEOREM FOR p-harmonic

UPPER AND LOWER SOLUTIONS FOR A HOMOGENEOUS DIRICHLET PROBLEM WITH NONLINEAR DIFFUSION AND THE PRINCIPLE OF LINEARIZED STABILITY

SEMILINEAR ELLIPTIC EQUATIONS WITH DEPENDENCE ON THE GRADIENT

Minimization problems on the Hardy-Sobolev inequality

Homogenization and error estimates of free boundary velocities in periodic media

Memoirs on Differential Equations and Mathematical Physics

Sharp blow-up criteria for the Davey-Stewartson system in R 3

Stability properties of positive solutions to partial differential equations with delay

THE BLOW UP OF THE SOLUTION OF FRACTIONAL ORDINARY DIFFERENTIAL EQUATIONS. Bambang Hendriya Guswanto

Some non-local population models with non-linear diffusion

Existence of a ground state and blow-up problem for a nonlinear Schrödinger equation with critical growth

H u + u p = 0 in H n, (1.1) the only non negative, C2, cylindrical solution of

Blow-up for a Nonlocal Nonlinear Diffusion Equation with Source

STABILITY RESULTS FOR THE BRUNN-MINKOWSKI INEQUALITY

SYMMETRY AND REGULARITY OF AN OPTIMIZATION PROBLEM RELATED TO A NONLINEAR BVP

Necessary Conditions and Sufficient Conditions for Global Existence in the Nonlinear Schrödinger Equation

ON A CONJECTURE OF P. PUCCI AND J. SERRIN

Volume Effects in Chemotaxis

Steven D. Taliaferro updated: February 2010 BIOGRAPHICAL SKETCH CURRENT OFFICE AND ADDRESSES AND PHONE NUMBER

Classical solutions for the quasi-stationary Stefan problem with surface tension

Symmetry of nonnegative solutions of elliptic equations via a result of Serrin

A GLOBAL COMPACTNESS RESULT FOR SINGULAR ELLIPTIC PROBLEMS INVOLVING CRITICAL SOBOLEV EXPONENT

REGULARITY AND COMPARISON PRINCIPLES FOR p-laplace EQUATIONS WITH VANISHING SOURCE TERM. Contents

SECOND TERM OF ASYMPTOTICS FOR KdVB EQUATION WITH LARGE INITIAL DATA

Heat equations with singular potentials: Hardy & Carleman inequalities, well-posedness & control

TOPICS IN NONLINEAR ANALYSIS AND APPLICATIONS. Dipartimento di Matematica e Applicazioni Università di Milano Bicocca March 15-16, 2017

Critical exponents for a nonlinear reaction-diffusion system with fractional derivatives

Decay rate of the compressible Navier-Stokes equations with density-dependent viscosity coefficients

A Dirichlet problem in the strip

Hardy inequalities, heat kernels and wave propagation

ALEKSANDROV-TYPE ESTIMATES FOR A PARABOLIC MONGE-AMPÈRE EQUATION

with C^{\infty} phases (see also [14]). We consider the asymptotic behavior of oscillatory integrals, that is, integrals of Here

On Solutions of Evolution Equations with Proportional Time Delay

On an Elementary Approach to Optimal Control with Neumann Boundary Condition

Singular solutions of partial differential equations modelling chemotactic aggregation

Global regularity of a modified Navier-Stokes equation

SUBSOLUTIONS: A JOURNEY FROM POSITONE TO INFINITE SEMIPOSITONE PROBLEMS

Existence and Multiplicity of Solutions for a Class of Semilinear Elliptic Equations 1

Weak solutions for some quasilinear elliptic equations by the sub-supersolution method

Liouville theorems for stable Lane-Emden systems and biharmonic problems

NONEXISTENCE OF GLOBAL SOLUTIONS OF CAUCHY PROBLEMS FOR SYSTEMS OF SEMILINEAR HYPERBOLIC EQUATIONS WITH POSITIVE INITIAL ENERGY

Spectral theory for magnetic Schrödinger operators and applicatio. (after Bauman-Calderer-Liu-Phillips, Pan, Helffer-Pan)

BLOW-UP AND EXTINCTION OF SOLUTIONS TO A FAST DIFFUSION EQUATION WITH HOMOGENEOUS NEUMANN BOUNDARY CONDITIONS

Transcription:

$(_{\square }^{\pm} \mathrm{f}\mathrm{f}\mathrm{l} \grave{7}\ovalbox{\tt\small REJECT})$ 1197 2001 189-195 189 Self-similar solutions to a parabolic system modelling chemotaxis Yuki Naito ( ) Department of Applied Mathematics, Kobe University ( ) Takashi Suzuki Department of Mathematics, Osaka University ( ) Kiyoshi Yoshida Faculty of Integrated Arts and Sciences, Hiroshima University ( ) ( ) We are concerned with the system of partial differential equations $\frac{\partial u}{\partial t}=\nabla\cdot(\nabla u-u\nabla v)$ (11) $\{$ $\tau\frac{\partial v}{\partial t}=\triangle v-\gamma v+u$ for and $t>0$, where $x\in \mathbb{r}^{n}$ $\tau>0$ and are constants This system is a mathematical model of chemotaxis (aggregation of organisms sensitive to the gradient of chemical $\gamma\geq 0$ substance) proposed by Keller and Segel [12] in 1970 The functions $u(x, t)$ and $v(x, t)$ in (11) denote the cell density of cellular slime molds and the concentration of the chemical substance at place and time $x$ $t$, respectively It is assumed that and are nonnegative $u$ $v$ We deal with a special class of solutions which are called self-similar solutions If, $\gamma=0$ then the system (11) is invariant under the similarity transformation $u_{\lambda}(x, t)=\lambda^{2}u(\lambda x, \lambda^{2}\mathrm{f})$ and $v_{\lambda}(x, t)=v(\lambda X, \lambda^{2}t)$ for $\lambda>0$, that is, if $(u, v)$ $(u_{\lambda}, v_{\lambda})$ is a solution of (11) globally in time, then so is A solution $(u, v)$ is said to be self-similar, when the solution is invariant under this transformation, that is, (12) $u(x, t)=u_{\lambda}(x, t)$ and $v(x, t)=v_{\lambda}(x, t)$ for all $\lambda>0$ Letting $\lambda=1/\sqrt{t}$ in (12), we see that $(u, v)$ has the form (13) $u(x, t)= \frac{1}{t}\emptyset(\frac{x}{\sqrt{t}})$ and $v(x, t)= \psi(\frac{x}{\sqrt{t}})$

190 for and $x\in \mathbb{r}^{n}$ $t>0$ By a direct computation it is shown that $(u, v)$ satisfies (11) if and $(\phi, \psi)$ only if satisfies (14) $\{$ $\nabla\cdot(\nabla\phi-\emptyset\nabla\psi)+\frac{1}{2}x\cdot\nabla\phi+\emptyset=0$ $\triangle\psi+\frac{\tau}{2}x\cdot\nabla\psi+\phi=0$ for $x\in \mathbb{r}^{n}$ It follows that $\int_{\mathbb{r}^{n}}u(x, t)dx=t^{(n-2)}/2\int_{\mathbb{r}^{n}}\phi(y)dy$ for Therefore self-similar solution $\phi\in L^{1}(\mathbb{R}^{N})$ $(u, v)$ preserves the mass $ u(\cdot, t) _{L^{1}(\mathbb{R}^{N})}$ if and only if $N=2$ Henceforth we study the case $N=2$ We are concerned with the $(\phi, \psi)\in C^{2}(\mathbb{R}^{2})\cross C^{2}(\mathbb{R}^{2})$ classical solutions of (14) satisfying (15) $\phi,$ $\psi\geq 0$ in $\mathbb{r}^{2}$ and $\phi(x),$ $\psi(x)arrow \mathrm{o}$ as $ x arrow\infty$ Define the solution set $S$ of (14) as (16) $S=$ { $(\phi,$ $\psi)\in C^{2}(\mathbb{R}^{2})\cross C^{2}(\mathbb{R}^{2}):(\phi,$ $\psi)$ is a solution of (14) with (15)} The problem of existence of self-similar solutions has been studied extensively The $(\phi, \psi)$ existence of radial solutions of (14) has been obtained by Mizutani and Nagai [15] It has shown by Biler [1] that there is an upper bound on the mass of self-similar solutions More precisely, the system (14) with $\tau=1$ $(\phi, \psi)$ has no radial solutions satisfying $ \emptyset _{L(\mathbb{R}^{2})}1/2\pi\geq 782\ldots$ Furthermore, for every $M\in(0,8\pi)$, there exists a radial solution satisfying In this paper we investigate the structure $(\phi, \psi)$ $ \emptyset _{L^{1}}(\mathbb{R}^{2})=M$ of the solution set defined by $S$ (16) more precisely First we show the system (14) is reduced to a single ordinary differential equation Put (17) $\phi(x)=\sigma e^{- x ^{2}/}e4\psi(x)$, $\phi$ where a is a positive constant Then a solutions of satisfies the first equation of (14), and so if we find (18) $\triangle\psi+\frac{\tau}{2}x\cdot\nabla\psi+\sigma e^{- x ^{2}/}4\psi e=0$ in $\mathbb{r}^{2}$, we can obtain the solution of (14) In $(\phi, \psi)$ $[15, 16]$ they have shown the existence of radial solutions of (18) satisfying (19) $\psi(x)arrow 0$ as $ x arrow\infty$

$\mathbb{r}_{f}$ that 191 by investigating the corresponding ordinary differential equation following: Conversely, we have Theorem 1 Assume that is a nonnegative solution of (14) satisfying $(\phi, \psi)$ $\phi,$ $\psi\in$ $\phi$ Then and are positive and satisfy (17), where $\sigma>0$ is a constant Assume $L^{\infty}(\mathbb{R}^{2})$ $\phi$ furthermore that (19) holds Then and are radially symmetric about the origin, and satisfy $\phi_{r}<0$ and for $\psi_{r}<0$ $r>0$, and $\phi(x)=o(e^{- x /4})2$ and $\psi(x)=o(e^{-\min\{\mathcal{t}} )1\} x 2/4$ as $ x arrow\infty$ The proof of Theorem 1 consists of two steps First we reduce the system (14) to the equation (18) by employing the Liouville type result essensially due to Meyers and Serrin [14] Then we show the radial symmetry of solutions by the method of moving planes This device was first developed by Serrin [23] in PDE theory, and later extended and generalized by Gidas, Ni, and Nirenberg $[6, 7]$ With a change of variables we are still able to obtain a symmetry result for the equation (18) as in [18] Next we investigate the structure of the solution set $S$ defined by (16) Fr om Theorem 1, the set contains $S$ nonnegative solutions satisfying and (19) For $(\phi, \psi)$ $\phi\in L^{\infty}(\mathbb{R}^{2})$ $(\phi, \psi)\in S,$ $\phi$ $\phi,$ and are radially symmetric about the origin, and satisfy $\psi\in L^{1}(\mathbb{R}^{2})$ Theorem 2 The solution set $S$ is written by one parameter families $(\phi(s), \psi(s))$ on $s\in$ $is_{f}s=\{(\phi(s), \psi(s)) : s\in \mathbb{r}\}$ The solutions $(\phi(s), \psi(s))$ and $\lambda(s)= \phi(s) _{L^{1}(\mathbb{R})}2$ the following properties: (i) and are $s-\succ(\phi(s), \psi(s))\in C^{2}(\mathbb{R}^{2})\cross C^{2}(\mathbb{R}^{2})$ continuous; $srightarrow\lambda(s)\in \mathbb{r}$ (ii) $(\phi(g), \psi(s))arrow(\mathrm{o}, 0)$ in $C^{2}(\mathbb{R}^{2})\cross C^{2}(\mathbb{R}^{2})$ $\lambda(s)arrow \mathrm{o}$ and as $sarrow-\infty$ ; (iii) $ \psi(s) _{L^{\infty}(\mathbb{R})}2arrow\infty$ as, $sarrow\infty$ and $satisf\dot{y}$ $\lambda(s)arrow 8m\pi$ and $\phi(s)dxarrow 8m\pi\delta_{0}(dX)$ as $sarrow\infty$ in the sense of measure for some integer $m$ satisfying $1 \leq m\leq\max\{1, [\pi^{2}\tau^{2}/6]\}$, where $[a]$ is the greatest integer not exceeding $a$ and $\delta_{0}(dx)$ denotes Dirac $fs$ delta function with the support in origin Moreover, (iv) Let $\lambda^{*}=\sup_{s\in \mathbb{r}}\lambda(s)$ $\int_{\mathbb{r}^{2}}e^{-1}edyy ^{2}/4\psi(_{S})arrow\infty$ as $sarrow\infty$ ; Then (v) If $0<\tau\leq 1/2$ then $0<\lambda(s)<8\pi$ for $s\in $8m \pi\leq\lambda^{*}\leq\max\{4\pi^{3}/3,4\pi^{3}\tau^{2}/3\})$ \mathbb{r}$ As a consequence of Theorem 2 we obtain the following:

$\partial \mathrm{z}\text{ }$ $\overline{\psi}_{\sigma}$ 192 $\lambda^{*}$ Corollary 1 There exist an integer $m$ and a constant satisfying $1 \leq m\leq\max\{1, [\pi^{2}\tau^{2}/6]\}$ and $8m \pi\leq\lambda^{*}\leq\max\{4\pi^{3}/3,4\pi^{3}\tau^{2}/3\}$, respectively, such that (i) for every, there exists a solution satisfying $\lambda\in(0, \lambda^{*})$ $(\phi, \psi)\in S$ $ \emptyset _{L(\mathbb{R}^{2})}1=\lambda$ ; $\lambda>\lambda^{*}$ (ii) for, there exists no solution $(\phi, \psi)\in S$ satisfying $ \phi _{L(\mathbb{R}^{2})}1=\lambda_{i}$ (iii) there exists a sequence $(\phi_{k}, \psi_{k})\subset S$ satisfying $\phi_{k}dxarrow 8m\pi\delta 0(dx)$ as $karrow\infty$ in the sense of measure Moreover, if $0<\tau\leq 1/2$ then $m=1$ and $\lambda^{*}=8\pi$ The proof of Theorem 2 is based on the ODE arguments Furthermore, we employ the blow-up analysis by Brezis-Merle [2] and Li-Shafrir [13] to investigate the asymptotic behavior of as $(\phi, \psi)\in S$ $ \psi _{L^{\infty(}}\mathbb{R}^{2}$ $arrow\infty$ $\phi$ ) To show the upper bounds of the mass of we use the techniques due to Bilar [1] Let bom (17) it follows that $\lambda= \phi _{L(\mathbb{R}^{2})}1$ $\lambda=\sigma\int_{\mathbb{r}^{2}}e^{-1y}e^{\psi}d(y)y ^{2}/4$ Then (18) is rewritten as the elliptic equation with a non-local term (110) $\triangle\psi+\frac{\tau}{2}x\cdot\nabla\psi+\lambda e^{- x ^{2}}e/4\psi/\int_{\mathbb{R}^{2}}e^{-1y}e^{\psi}d(y)y ^{2}/4=0$ $x\in \mathbb{r}^{2}$ for This equation plays an important role to investigate the blow-up properties of $(\phi, \psi)\in$ S Finally, we obtain the result concerning the existence of solutions to (18) with (19) This refines the previous results [15, Theorem 1], [16, Theorems 1 and 2], and [17, Theorem 11] Theorem 3 For any $\tau>0$ there exists $\sigma^{*}>0$ such that $\sigma>\sigma^{*}$ (i) if, then (18) with (19) has no solution; $\sigma--\sigma^{*},$ (ii) $(18)$ if with (19) has at least one solutionj (iii) if $0<\sigma<\sigma^{*}$, then (18) with (19) $\underline{\psi}_{\sigma},$ has at least two distinct solutions satisfying and $\lim_{\sigmaarrow 0}\underline{\psi}_{\sigma}(0)=0$ $\lim_{\sigmaarrow 0}\overline{\psi}_{\sigma}(0)=\infty$ Recently, attentions have been paid to blowup problems for the system (11) for $(x, t)\in$ subject to the boundary and initial condition $\Omega\cross(0, T)$ (111) $\{$ $\underline{\partial u}\underline{\partial v}==0$ $\partial\nu$ on $\partial\omega\cross(0, T)$, $u(x, 0)=u_{0}$ and $v(x, 0)=v_{0}$ on $\Omega$,

193 $\Omega\subset \mathbb{r}^{2}$ $\partial\omega$ where is a bounded domain with smooth boundary, and l is the outer normal unit vector Childress and Percus [4] and Childress [3] have studied the stationary problem and have conjectured that there exists a threshold of blowup, that is, if $ u_{0} _{L^{1}()}\Omega=8\pi$ $ u_{0} _{L^{1}(\Omega)}<8\pi$ then the solution $(u, v)$ exists globally in time, and if $ u_{0} _{L()}1\Omega>8\pi$ then $u(x, t)$ can form a delta function singularity in finite time Their arguments were heuristic, while recent studies are supporting their validity rigorously, see, [21] We also refer to [9], [19], and [22] On the other hand, it is asserted that self-similar solutions take an important role for the Cauchy problem for the semilinear parabolic equations on the whole space, see, eg, [5], [10], and [11] By the definition, self-similar solutions are global in time, and they are expected to describe large time behavior of general solutions generically From Corollary 1, we are led to the following conjectures for the Cauchy problem (11) with $\gamma=0$ For $0<\tau\leq 1/2$, if $ u_{0} _{L(\mathbb{R}^{2})}1<8\pi$ then the solution of the Cauchy problem exists globally in time, and $if u_{0} _{L()}1\Omega>8\pi$ then the solution can blowup in a finite time REFERENCES [1] P Biler, Local and global solvability of some parabolic systems modelling chemotaxis, Adv Math Sci Appl 8(1998), 715-743 [2] H Brezis and F Merle, Uniform estimaes and blow-up behavior for solutions of $-\triangle u=v(x)e^{u}$ in two dimensions, Comm Partial Differential Equations 16 (1991), 1223-1253 [3] S Childress, Chemotactic collapse in two dimensions, Lecture Notes in Biomath, 55, Springer, 1984, 217-237 [4] S Childress and J K Percus, Nonlinear aspects of chemotaxis, Math Biosci 56 (1981), 217-237 [5] M Escobedo and 0 Kavian, Variational problems related to self-similar solutions for the heat equation, Nonlinear Anal TMA 11 (1987), 1103-1133 [6] B Gidas, W-M Ni, and L Nirenberg, Symmetry and related properties via the maximum principle, Comm Math Phys 68 (1979), 209-243

, 194 [7] B Gidas, W-M Ni, and L Nirenberg, Symmetry of positive solutions of nonlinear $\mathbb{r}^{n}$ elliptic equations in in ((MathematiCal Analysis and Applications, part A (L Nachbin, Ed), Adv Math Suppl Stud, Vol 7, 369-402, Academic Press, New York, 1981 [8] D Gilbarg and N S Trudinger, Elliptic partial differential equations of the second order, Springer-Verlag, Berlin, 1983 [9] W J\"ager and S Luckhaus, On explosions of solutions to a system of partial differential equations modelling chemotaxis, Trans Amer Math Soc 329 (1992), 819-824 [10] O Kavian, Remarks on the large time behavior of a nonlinear diffusion equation, Annal Institut Henri Poincar\ e-analyse Nonlin\ eaire 4 (1987), 423-452 [11] T Kawanago, Asymptotic behavior of solutions of a semilinear heat equation with subcritical nonlinearity, Annal Institut Henri Poincar\ e-analyse Nonlin\ eaire 13 (1996), 1-15 [12] E F Keller and L A Segel, Initiation of slime mold aggregation viewed as an instability, J Theor Biol 26 (1970), 399-415 [13] Y-Y Li and I Shafrir, Blow-up analysis for solutions of $-\triangle u=ve^{u}$ in dimension two, Indiana Univ Math J 43 (1994), 1255-1270 [14] N Meyers and J Serrin, The exterior Dirichlet problem for second order elliptic partail differential equations, J Math Mech 9 (1960), 513-538 [15 Y Mizutani and T Nagai, Self-similar radial solutions to a system of partial differential equations modelling chemotaxis, Bull Kyushu Inst Tech (Math Natur Sci), 42 (1995), 19-28 [16] Y Mizutani, N Muramoto and K Yoshida, Self-similar radial solutions to a parabolic system modelling chemotaxis via variational method, Hiroshima Math J 29 (1999), 145-160 [17] N Muramoto, Y Naito and K Yoshida, Existence of self-similar solutions to a parabolic system modelling chemotaxis, Japan J Indust Appl Math (to appear) [18] Y Naito and T Suzuki, Radial symmetry of self-similar solutions $\mathrm{f}\mathrm{o}\mathrm{r}/$ heat equations, J Differential Equations 163 (2000), 407-428 semilinear

\mathrm{m}\mathrm{a}\mathrm{x}\mathrm{i}\mathrm{m}\mathrm{u}\mathrm{m}$ Principles 195 [19] T Nagai, Blow-up of radially symmetric solutions to a chemotaxis system, Adv Math Sci Appl 5 (1995), 581-601 $ \zeta [20] M Protter and H Weinberger, in Differential Equations, Prentice-Hall, Englewood Cliffs, New Jersey, 1967 [21] T Senba and T Suzuki, Chemotactic collapse in a parablic-elliptic system of mathematical biology, Adv Differential Equations (to appear) [22] T Senba and T Suzuki, Parabolic system of Chemotaxis: blow-up in a finite and the infinite time, preprint [23] J Serrin, A symmetry problem in potential theory, Arch Rational Mech Anal 43 (1971), 304-318