WILLETTA TOOLE-SIMMS

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ACADEMIC VITA FOR WILLETTA TOOLE-SIMMS ADDRESS Department of Biology Azusa Pacific University Azusa, CA 92557 (626) 969-3434 EDUCATIONAL BACKGROUND 1991-1992 Postdoctoral Training Chancellor s Postdoctoral Fellow University of California, Riverside Division of Biology, Advisor: Dr. Katherine Atkinson Topic: Role of Sphingolipids in Signal Transduction 1988-1990 Postdoctoral Training Wesley Postdoctoral Scholar Kansas State University Division of Biology Advisor: Dr. Terry Johnson Topic: Negative Regulation of Cell Proliferation 1982-1988 Ph. D. (cell biology) Purdue University Division of Biology Advisor: Dr. Frederick Crane Topic: Positive Regulation of Cell Proliferation 1978-1982 B. S. degree

Stillman College Department of Biology Honor Thesis Advisor: Dr. Jarnail Singh RESEARCH INTEREST Dr. Simms research interests are in the regulation of cell growth, especially in cancer cells, and immunology. HONORS Stillman College President of Gamma Iota Sigma Honor Society Alpha Kappa Mu National Honor Society MBRS Fellow Basilus of Alpha Kappa Alpha Sorority Who s Who Among College Students Fisk University Academic honors in the United Negro College Fund Pre-medical Program Purdue University Recipient of Purdue Minority Fellowship Member of Black Graduate Association Recipient of MARC Travel Award Kansas State University Wesley Postdoctoral Scholar University of California, Riverside Chancellor s Postdoctoral Scholar Azusa Pacific University Recipient of Promega Training Grant (2000-2001, 2002-2003) Recognition of Service (5 and 10 years) Who s Who Among American Teachers (2004, 2005, 2006) Recipient of Faculty Research Grant Effects of Cayenne Pepper and Green Tea on the Reversal of Uncontrolled Cellular Growth (2000-2001) Recipient of creative teaching grant A Model to Teach the Transition from Genotype to Phenotype(2005-2006) RECENT PUBLICATIONS AND REVIEWS From Genotype to Phenotype, Willetta Toole-Simms, Designing, Implementing and Sustaining a Research-Supportive

Undergraduate Curriculum: A Compendium of Successful Curricular Practices from Faculty and Institutions Engaged in Undergraduate Research, New CUR Publication- Research Supportive UG Curriculum, Washington, D. C, (2007)

PUBLICATIONS STILLMAN COLLEGE The Effects of Ochratoxin A on Fetuses of White Mice W. Toole, MBRS Honor Thesis PURDUE UNIVERSITY Retinoic Acid Inhibition of Transplasmalemma Diferric Reductase, I. L Sun, W. Toole-Simms, F. L Crane, E. S. Golub, T. Diaz de Pagan, D. J. Morre and H. Low, Biochemical and Biophysical Research Communication 146:976-982, 1987 Diferric Transferrin Reduction Stimulates the Na+/H+ Antiport of HeLa Cells, I. L Sun, r. Garcia-Canero, W. Liu, W. Toole-Simms, and F. L. Crane, Biochemical and Biophysical Research Communication 145: 467-473, 1987 Regulation of Hydrogen Release from HeLa Cells by Diferric Transferrin W. Toole-Simms, Journal of Bioenergetics and Biomembranes 20: 257-264. Reduction of Diferric Transferrin by SV40 Transformed Pineal Cells Stimulate Na+/H+ Antiport Activity I. L. Sun, W Toole-Simms, F. L. Crane and D. J. Morre Biochimica et Biophysica Acta 938:17-23, 1988 Transformation With SV40 Virus Prevents Retinoic Acid Inhibition of Plasma Membrane NADH Diferric Transferrin Reductase in Rat Liver Cells, I. L. Sun, W. Toole- Simms, and F. L. Crane, Journal of Bioenergetics and Biomembranes, 20:383-391, 1988 Transplasma Membrane Electron and Proton Transport is Inhibited by Chloroquine, W. Simms and D. J. Morre, Biochemistry International 21: 761-769, 1990 Inhibition of Transplasma Membrane Electron Transport by Monoclonal Antibodies to the Transferrin Receptor, W. Toole-Simms, H. Low, and W. P. Faulk, Biochemical and Biophysical Research Communication 176:1437-1442. KANSAS STATE UNIVERSITY The Effects of a Sialoglycopeptide on Early Events Associated with Signal Transduction, W. Toole-Simms, D. K. Lodger, H. K Fattaey, and T. C. Johnson, J. Cell Physiology 147: 292-297, 1991

Identification of a Cell Surface Component of Swiss 3T3 Cells Associated with and Inhibition of Cell Division. S. S. Lakshmannarao, W. Toole-Simms, H. K. Fattaey, R. J. Leach and T. C. Johnson, Experimental Cell Research 195:421-425, 1991 ABSTRACTS PURDUE UNIVERSITY Diferric Transferrin Reductase in the Plasma Membrane Activates the Na+/H+ Antiport and is Inhibited by Retinoic Acid, American Society of Cell Biology, 1987 KANSAS STATE UNIVERSITY Binding of a Sialoglycopeptide to a Specific Cell Surface Receptor Inhibits Cell Division in G 1 Western Central State Biochemistry AZUSA PACIFIC UNIVERSITY Isolation of Sphingolipid Bacteria Mutants, West Coast Undergraduate Research Conference San Francisco, CA May, 1993 Effects of Cayenne Pepper and Green Tea on the Reversal of Uncontrolled Cellular Growth:, West Coast Undergraduate Research Conference, Santa Clarita, CA, May, 2002 PRESENTATIONS AZUSA PACIFIC UNIVERSITY A Doll Model for Gene Conversion to Phenotype, Association of Christian School International, Anaheim, CA 2002 How To Teach Cancer Biology, Association of Christian School International, Anaheim, CA 2003 How To Teach About Immunology, Association of Christian School International, Anaheim, CA 2005 Expensive Experiments on a Simple Budget, Association of Christian School International, Anaheim, CA 2006 OTHER SCHOLARLY AND SERVICE ACTIVITIES

REVIEWS INQUIRY INTO LIFE LABORATORY MANUAL by Sylvia Mader, (labs #1,2,3 and 4), 10th edition, 2003 BIOLOGY: CONCEPTS AND CONNECTIONS by Peter Campbell (chapter 11 ) 4 th edition, 2003 CONCEPTS AND CONNECTIONS: INTRODUCTION TO BIOLOGY by Presson and Jenner (chapters 9, 11 12), 1 st edition, CONCEPTS IN BIOLOGY by Enger/Ross/Bailey 11 th edition, MADER, BIOLOGY LABORATORY MANUAL, by Sylvia Mader, 8 th edition BIOLOGY: CONCEPTS AND APPLICATIONS by Cecil Starr, 7 th edition