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MA 138 Calculus 2 for the Life Sciences SECOND MIDTERM Spring 2014 3/11/2014 Name: Sect. #: Answer all of the following questions. Use the backs of the question papers for scratch paper. No books or notes may be used. You may use a calculator. You may not use a calculator that has symbolic manipulation capabilities. When answering these questions, please be sure to: check answers when possible, clearly indicate your answer and the reasoning used to arrive at that answer (unsupported answers may receive NO credit). QUESTION SCORE TOTAL 1. 10 2. 10 3. 10 4. 15 5. 10 6. 15 7. 10 8. 10 9. 10 Bonus. 10 TOTAL 100

Please make sure to list the correct section number on the front page of your exam. In case you forgot your section number, consult the following table: Sections # Lecturer Time/Location 001-004 Alberto Corso MWF 10:00 am - 10:50 pm, CB 122 Section # Recitation Instructor Time/Location 001 Dustin Hedmark TR 09:30 am - 10:20 am, CB 337 002 Dustin Hedmark TR 12:30 pm - 01:20 pm, CB 336 003 Liam Solus TR 02:00 pm - 02:50 pm, POT 110 004 Liam Solus TR 03:30 pm - 04:20 pm, CB 339

1. Match each of the following direction fields (or, better, phase portraits), labeled A-C, with the appropriate differential equation, labeled I-III: I II III dy dx = x y dy dx = x (2 y) dy dx = 2 y Answers: A: B: C:

2. Solve the differential equation with initial condition y(0) = 1. dy + xy = 2x dx

Differential equations have been used extensively in the study of drug dissolution for patients given oral medications. One of the simplest such models is given by the Noyes-Whitney equation. 3. The dynamics of the drug concentration c (in mg/ml) in the Noyes-Whitney model is governed by the differential equation dc dt = k(c s c), where k > 0 and c s > 0 are constants: k is the dissolution rate of the drug and c s is the drug concentration in the stagnant layer. (i) (2 pts) Is this differential equation pure-time, autonomous, or something else? (ii) (6 pts) Solve the differential equation for the initial condition c(0) = 0. (iii) (2 pts) Using (ii), find the limit of the drug concentration c as t.

4. A simple model of predation: Suppose that N(t) denotes the size of a population at time t. The population evolves according to the logistic equation, but, in addition, predation reduces the size of the population so that the rate of change is given by ( dn dt = N 1 N ) 20 7N 4 + N. (*) The first term on the right-hand side describes the logistic growth; the second term describes the effect of predation. ( For your convenience, the function g(n) = N 1 N ) 7N is graphed below 20 4 + N dn/dt N g(n) (a) (4 pts) Find (algebraically) all the equilibria N of ( ).

(b) (4 pts) Use the graph of g(n) to classify the stability of the equilibria N found in (a). ( (c) (4 pts) Find g (N), where g(n) = N 1 N ) 7N 20 4 + N. (d) (3 pts) Use the eigenvalues method (stability criterion) to classify the stability of the equilibria N found in (a). pts: /15

dy 5. Consider the autonomous differential equation dx = g(y). The graph of dy/dx as a function of y is given below. (a) (2 pts) Use the graph on the right to find the equilibria ŷ of the differential equation. dy/dx g(y) (b) (5 pts) Use the graph on the right and the geometric approach to discuss the stability of the equilibria you found in (a). 4 3 2 1 0 1 2 3 4 y (c) (3 pts) Using the information found in (a) and (b), which of the following direction fields (phase portraits) matches the given differential equation? Circle the correct one.

6. (9 pts) Solve the following system of linear equations x + 2y z = 2 x + 4y + 3z = 8 3x + 8y + z = 12 by writing the corresponding augmented matrix and then by row reducing.,

(3 pts) How many solutions does the system have? (3 pts) Which of the two pictures below illustrates the geometric situation described by the given system of linear equations? Explain your choice. pts: /15

7. (a) (5 pts) The solution(s) for the system of linear equations corresponding to the following augmented matrix 1 0 2 0 0 1 7 10 0 0 0 5 is (are): (b) (5 pts) The solution(s) for the system of linear equations corresponding to the following augmented matrix 1 0 4 6 0 1 5 4 0 0 0 0 is (are):

8. Let A = 1 2 0 1 1 0 (a) Compute 3A 1 2 B., B = 4 2 0 8 6 14, C = [ 3 1 2 2 0 1 ]. (b) Compute the product AC. (c) Compute the product CA.

9. Find the values of a and b that satisfy the following matrix equation: [ ] ( [ ] ) T 0 2 1 2a = 1 [ ] 40 8. 6 a 1 1 2 2 2 b (Recall that the notation A T denotes the transpose of the matrix A. Our textbook uses the alternative notation A.)

Bonus. Choose only one of the following two problems: (a) A pharmaceutical company makes up a vitamin capsule using different recipes for men and women. In each capsule, the recipe calls for 80 units of vitamin B 12 and 50 units of vitamin C in the capsules for men, and 70 units of vitamin B 12 and 40 units of vitamin C in the capsules for women. If the manufacturer uses 13 units of vitamin C for every 22 units of vitamin B 12, then what is the gender ratio of the customer base? (b) There are various possibilities for modeling tumor growth. For instance, a tumor can be modeled as a spherical collection of cells and that it acquires resources for growth only through its surface area. All cells in a tumor are also subject to a constant per capita death rate. With these assumptions, the dynamics of tumor mass M (in grams) is therefore modeled by the differential equation dm dt = κm 2/3 µm, where κ and µ are positive constants. The first term represents tumor growth via nutrients entering through the surface; the second term represents a constant per capita death rate. Suppose κ = 1, that is the dynamics of tumor mass is modeled as dm dt = M 2/3 µm. Which value does the tumor mass approach as time t? Justify your answer.