LESSON PLAN FOR EVEN SEM SESSION TOPIC: DRUGS DESIGN. Introduction to Drugs and Its. Discovery of New Drugs

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1 LESSON PLAN FOR EVEN SEM SESSION NAME OF ASSISTANT PROFESSOR CLASS/SECTION SUBJECT : VAISHALI DHAMIJA : MSC (FINAL) : ORGANIC CHEMISTRY UNIT IV( PAPER XX) DATE DATE DATE DATE DATE DATE DATE DAY 4 DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE : DRUGS DESIGN Introduction to Drugs and Its Classification Organic Preparation Discovery of New Drugs Organic Preparation History and development of Chemotherapeutic agents. Organic Preparation Organic Preparation Elementary idea about drug action: Therapeutic index Organic Preparation LD 50 & ED 50 and Naming of New Drugs The receptor role and Neurotramitters. Organic Preparation Ion channels and their control, Membrane bound enzymes-activa tion/deactivation Organic Preparation POWER POINT PRESENTATION. Chemical basis of messenger induced change of shape by the receptor, design of agonists, antagonists and partial agonists 1

2 0 DATE DAY 11 DATE DATE DATE DAY 12 DATE DATE DATE DATE DATE DATE DATE DATE Organic Preparation Isosters and bioisosteres,concept of lead compounds Organic Preparation structure-activity relationships Organic Preparation. TEST Organic Preparation Brief overview of pharmacokinetics and pharmacodynamics Organic Preparation concept of prodrugs and synergism Revision NAME OF ASSISTANT PROFESSOR: VAISHALI DHAMIJA CLASS/SECTION: MSC (PREVIOUS) SUBJECT: ORGANIC CHEMISTRY UNIT/PART I Introduction to Reaction of Carbonyl DATE Compounds Mannich Reaction DATE DAY 3 Reformatsky reaction DATE Dieckmann reaction DATE Wittig reaction, Cannizzaro reaction DATE DATE TEST DATE Claisen condensation and Aldol condensation DATE DATE

3 0 DATE DATE DATE DATE DATE DATE DATE Benzoin condensation and Knoevenagal condensation Perkin reaction, Reduction with Grignard Reagent Reduction with lithium aluminium hydride reduction of carbonyl compounds, acids, esters, nitriles. Ester hydrolysis, aminolysis of esters, amide hydrolysis Hydration and Addition of Alcohols to Aldehydes, Ketones and Acids. NAME OF ASSISTANT PROFESSOR CLASS/SECTION SUBJECT : VAISHALI DHAMIJA : B.SC (III)/A : PHYSICAL CHEMISTRY UNIT/PART I DATE : SOLUTIONS Methods of expressing concentrations of solutions ---- DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE Dilute solutions and Raoult s law Determination of Strength of given Acid Potentiometrically Ideal and non-idea solutions ---- Colligative property: Relative lowering of ---- vapour pressure ---- Qualitative analysis of inorganic mixture Elevation in boiling point ---- Depression in freezing point Qualitative analysis of inorganic mixture Osmotic Pressure

4 0 DATE DATE DATE DATE DATE DATE UNIT/PART DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE Thermodynamic derivation of relation ---- between amount of solute and elevation in boiling point Qualitative analysis of inorganic Thermodynamic derivation of relation between amount of solute and depression in freezing point Abnormal Mol. Mass and van t Hoff factor ASSIGNMENT Qualitative analysis of inorganic Applications in calculating molar masses of ---- normal, dissociated and associated solutes in solution Introduction to Photochemistry Qualitative analysis of inorganic Interaction of radiation with matter, ---- Difference between thermal and photochemical processes with examples Laws of photochemistry: Grotthus-Drapper ---- law, Stark-Einstein law ---- Qualitative analysis of inorganic TEST ---- Lumeniscence, fluorescence and ---- phosphorescence ---- Qualitative analysis of inorganic ASSIGNMENT 2, Jablonski diagram ---- depiciting various processes occurring in the excited state, qualitative description of fluorescence, phosphorescence, non-radiative processes (internal conversion, intersystem crossing) Quantum yield and its calculation using ---- suitable examples, Photosensitized reactionsenergy transfer processes (simple examples) 4

5 1 DATE DATE UNITII/PART IV DATE DAY 2 DATE DATE DATE DATE DATE DATE DAY08 DATE UNIT-I/PART-I DATE DATE DATE DATE DATE DATE Qualitative analysis of inorganic CONDITIONAL TEST ---- Statement and meaning of the terms phase, component and degree of freedom Phase Rule & thermodynamic derivation of Gibbs phase rule Qualitative analysis of inorganic Phase equilibria of one component system --- Example water system Phase equilibria of two component systems --- solid-liquid equilibria, simple eutectic Example Pb-Ag system, Desilverisation of Pb --- Viva of Qualitative analysis of inorganic mixture(practical ) Introduction and need of statistical mechanics, --- Thermodynamic probability Maxwell-Boltzmann distribution statistics ---,Born oppenheimer approximation. --- Test of Organic Preparations Partition function and its physical significance, --- Factorization of partition function --- REVISION AND DISCUSSION OF DOUBTS. NAME OF ASSISTANT PROFESSOR CLASS/SECTION SUBJECT : VAISHALI DHAMIJA : B.SC (II) : CHEMISTRY UNIT/PART I DATE S. Determination of CST of Phenol- Water System 5

6 DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE Detemination of Solubility of Benzoic Acid and its enthalpy change Analysis of Organic compound (Explaination) Analysis of Organic compound(preparation of L.E) and Test of Extra element) Analysis of Organic compound(preparation of L.E) and Test of Extra element) Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound Analysis of Organic compound. 6

7 3 DATE DATE DATE DATE DATE DATE DATE DATE DATE DATE Analysis of Organic compound Test of Analysis of Organic compound Test of Analysis of Organic compound Viva Test of Inorganic Preparations and Viva Test of Physical Practicals Viva of Physical Practicals Revision of Full syllabus and Discussion of Doubts. NAME OF ASSISTANT PROFESSOR CLASS/SECTION SUBJECT UNIT I DATE DATE Introduction to Chemical Kinetics, Rate of Reaction, expressing rate of Reaction Measurement of Rate of Reaction & Factors Affecting Rate of Reaction(Nature of Reactant) : VAISHALI DHAMIJA : BSC (I)/ B : PHYSICAL CHEMISTRY Redox Titration of Determination of Oxalate ions using Pot. Dichromate. Redox Titration of Determination of Ferrous ions using Pot. Dichromate. DATE DATE DATE DAY 6 DATE DATE Factors Affecting Rate of Reaction(Concentration and temperature Factors Affecting Rate of Reaction(Temperature) Factors Affecting Rate of Reaction(Catalyst and Nature of solvent) Order of Reaction, Units And Numericals. No. Method.(theory) No. Method. No.Method weight Method. 7

8 DATE DATE DATE DATE DATE DATE DATE DATE UNIT II DATE SPORTS DAY Integrated Rate Expression for Zero Order and Numericals. Integrated Rate Expression for First Order and Numericals Integrated Rate Expression for 2 nd Order and Numericals. Integrated Rate Expression for 3 rd Order and Numericals ASSIGNMENT 1 Half life period of a reaction. Effect of temperature on the rate of reaction Arrhenius equation. Theories of reaction rate:simple collision theory for unimolecular collision and Transition State theory. Electrolytic conduction, factors affecting electrolytic conduction, specific conductance, molar conductance, equivalent conductance. weight Method Determination of Viscosity of Given Liquid Determination of Viscosity of Given Liquid To determine the specific refractivity of given organic compound. To determine the specific refractivity of given organic compound. Det. Of Surface tension of surfactant solution. Det. Of Surface tension of surfactant solution. CLASS TEST Determination of Mg 2+ by EDTA DATE Variation of Conductance with concentration Determination of Zn 2+ by EDTA DATE and Arrhenius theory of ionization. DATE Ostwald s Dilution Law, Debye- Huckel Onsager s equation for strong electrolytes Test of preparation of organic compounds Kohlrausch s Law and its Application of in Purification of Oganic compound DATE calculation of conductance of weak electrolytes at infinite dilution and its Numericals DAY 6 ASSIGNMENT 2,Applications of Purification of Oganic compound DATE conductivity measurements: determination of degree of dissociation, determination of Ka of acids & Its Numericals Determination of solubility product of Revision of Physical Practicals DATE sparingly soluble salts and Numerical. CONDITIONAL TEST Revision of Physical Practicals DATE CONDITIONAL TEST Revision of Physical Practicals DATE Conductometric titrations Viva DATE DA11 Concepts of ph and pka Viva 8

9 DATE DATE DATE DATE DATE DATE DATE Buffer solution and buffer action NUMERICALS Henderson Hazel equation NUMERICALS CLASS TEST REVISION OF FULL SYLLABUS AND DISCUSSION OF DOUBTS. Revision of Volumetric Analysis Revision of Volumetric Analysis Paper Chromatography Paper Chromatography Revision of full Syllabus Discussion of Doubts VAISHALI DHAMIJA (NAME OF TEACHER) 9

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