CORUS R, D and T, Swinden Technology Centre, Rotherham, UK S60 3AR. HALL ANALYTICAL LABORATORIES, Manchester, UK M23 9YJ
|
|
- Darren Cameron
- 5 years ago
- Views:
Transcription
1 THE SUPELCO DIOXIN PREP SYSTEM - FLORISIL VERSION : A MULTI-LAYER SILICA GEL COLUMN CONNECTED IN SERIES TO AN ACTIVATED FLORISIL MICRO-COLUMN FOR RAPID DETERMINATIONS OF PCDD/Fs AND PCBs IN ENVIRONMENTAL SAMPLES Eric Aries 1, David R. Anderson 1, Nicholas Ordsmith 2, Lisa Fitzpatrick 3 and Fiona Barclay 3 1 CORUS R, D and T, Swinden Technology Centre, Rotherham, UK S60 3AR 2 HALL ANALYTICAL LABORATORIES, Manchester, UK M23 9YJ 3 SIGMA ALDRICH COMPANY Ltd., Poole, Dorset, UK BH12 4QH 1 POPs Workshop_30March2006
2 Overview Brief review on standard analytical procedures for PCDD/Fs and PCB analyses Collaboration between Corus / Hall Analytical / Supelco on the Dioxin Prep Systems Supelco Dioxin Prep Systems Dual Carbon Column Version Florisil Version Validation data Sample throughput Acknowledgements 2
3 Standard analytical procedures for PCB and PCDD/F analyses Method US EPA 1613 B : PCDD/Fs in solids, waste waters and sediments Method US EPA 23 : PCDD/Fs in stack emissions Method EN1948 : European method for PCDD/Fs and PCBs in stack emissions Method 1668A : PCBs in water, soil sediment and tissue ISOTOPE DILUTION : 13 C 12 PCDD/F and PCB internal standards High Resolution Gas Chromatography / High Resolution Mass Spectrometry HRGC / HRMS SEVERAL DAYS OF SAMPLE PREPARATION Extraction (Soxhlet, Dionex ASE) Solvent concentration Successive clean-up steps (Silica, Florisil, Alumina, Activated Carbon) Data processing 3
4 Supelco Dioxin Prep System Collaboration Corus / Hall Analytical / Supelco 2002 : Development and validation of the Dioxin Prep System Dual Carbon Column Version in Japan for fast determinations of PCDD/Fs. (Japan Quality Assurance Organisation and Kawajyu Techno Service) 2003 : Evaluation of the Dioxin Prep System Dual Carbon Column Version by Corus and Hall Analytical prior to its UK commercial launch : A collaboration agreement is signed by Corus, Hall and Supelco to develop and validate an enhanced version of the Dioxin Prep System : Development and validation of the Supelco Dioxin Prep System - Florisil Version by Corus and Hall Analytical Laboratories. 4
5 Testing Laboratories Trace Organic Analysis Laboratory (Corus R, D and T) Hall Analytical Laboratories Hall Analytical Laboratories Manchester, UK Contract laboratory UKAS (ISO 17025) accreditation for PCDD/F and PCB analyses 2 HRGC HRMS instruments Corus R, D & T Swinden Technology Centre, Rotherham, UK Researches into the emissions and the formation of PCDD/Fs and PCBs from UK steel plants (iron ore sintering, EAF steel-making) UKAS (ISO 17025) accreditation for PCDD/F and PCB analyses Micromass Autospec Ultima HRGC - HRMS 5
6 Corus and Hall Analytical standard procedures for determination of PCDD/Fs and PCBs in environmental samples EMISSION OR DUST SAMPLES Addition of 13 C 12 PCBs & 2,3,7,8-PCDD/Fs EXTRACTION (ASE 200) MULTI-LAYERED SILICA CHROMATOGRAPHY PCBs Saturated hydrocarbons FLORISIL CHROMATOGRAPHY PCDD/Fs HRGC / HRMS US EPA 23 or 1613B EN-1948 BASIC ALUMINA CHROMATOGRAPHY Saturated hydrocarbons PCBs HRGC / HRMS Method 6 US EPA 1668 A
7 Sample throughput at Trace Organic Analysis Laboratory (Corus) using standard analytical methods 1 fully trained technician / 8 samples Extraction and concentration (ASE 200) = 1 to 2 days Multi-layer silica clean-up = 1 day Florisil step = 1 day Basic Alumina step = 1 day PCBs Analysis overnight Data processing = 1 day PCDD/Fs Analysis overnight Data processing = 1 day PCDD/Fs : 4 to 5 working days PCBs : 5 to 6 working days Additional Tasks : Packing and activation of columns 7
8 SUPELCO DIOXIN PREP SYSTEMS The dual-carbon column version Description Analytical methods Validation data The Florisil version Description Analytical methods Validation data Sample throughput using Supelco Dioxin Prep system - Florisil Version 8
9 Supelco Dioxin Prep System - Dual Carbon Column Version Carboxen 1016 (75 m 2 / g) Carboxen 1000 (1200 m 2 / g) Multi-layer Silica gel column Dual carbon reversible tube Silica gel layer Silica gel layer Vacuum manifold 9
10 Analytical procedure Dioxin Prep System Dual Carbon Column Version ENVIRONMENTAL SAMPLES EXTRACTION (ASE 200) Addition of 13 C 12 2,3,7,8-PCDD/Fs and WHO-12 PCBs Toluene 100 ml CLEAN - UP Dual - carbon column fitted to an empty silica column Back elution of dual-carbon column WASTE 200 ml n-hexane PCDD/F FRACTION HRGC / HRMS 10
11 Analysis of a waste sinter dust (QC material) for PCDD/Fs using the Dioxin Prep System- Dual Carbon Column Version Corus data using standard US EPA 23 analytical method (N = 59) Corus data using Dioxin Prep system (N = 2) Hall Analytical data using Dioxin Prep system (N = 3) ng / kg ,3,7,8-TCDD 1,2,3,7,8-PeCDD 1,2,3,4,7,8-HxCDD 1,2,3,6,7,8-HxCDD 1,2,3,7,8,9-HxCDD 1,2,3,4,6,7,8-HpCDD OCDD 2,3,7,8-TCDF 1,2,3,7,8-PeCDF 2,3,4,7,8-PeCDF 1,2,3,4,7,8-HxCDF 1,2,3,6,7,8-HxCDF 2,3,4,6,7,8-HxCDF 1,2,3,7,8,9-HxCDF 1,2,3,4,6,7,8-HpCDF 1,2,3,4,7,8,9-HpCDF OCDF Total I-TEQ (ng/kg)
12 Supelco Dioxin Prep System - Florisil Version Schematic 250 ml solvent reservoir (28449-U) 24/24mm PP Connector (21216-U) Multi-layered silica tube (28397-U) 6.35/10 mm Reducing union (28398-U) Florisil micro-column 6.35/10 mm Reducing union (28398-U) Vacuum Manifold (28403-U) 12
13 Supelco Dioxin Prep System - Florisil Version Multi-layer silica and activated Florisil MULTI - LAYER SILICA Designed to meet requirements of Japanese Industrial Standard Methods K / K Silica gel 0.9 g Glass filter Multi-layer Silica AgNO 3 (10%) 3g H 2 SO 4 (22%) 6g H 2 SO 4 (44%) 4.5g KOH(2%) 3g ACTIVATED FLORISIL Empty Florisil tubes and connectors. Flame sealed ampoules containing 1g activated Florisil (60/100 mesh) 13
14 Analytical procedure Dioxin Prep System - Florisil Version ENVIRONMENTAL SAMPLES EXTRACTION Addition of 13 C 12 labelled internal standards PCDD/Fs ELUTION 50 ml DCM CLEAN-UP Multi-layer silica Florisil micro-column WASTE + PCBs 175 ml n-hexane WASTE + PCBs 25 ml Hexane/DCM (98 / 2, v/v) PCDD/Fs WASTE (Mainly saturated hydrocarbons) ALUMINA CLEAN - UP PCBs HRGC / HRMS 14
15 PeCDFs HxCDFs HpCDFs Determination of PCDD/Fs in DX-3 certified reference sediment using the Dioxin Prep System Florisil Version ng / kg Certified values (ng / kg) DX-3 Replicate 1 (ng / kg) DX-3 Replicate 2 (ng / kg) DX-3 Replicate 3 (ng / kg) DX-3 Replicate 4 (ng / kg) ,3,7,8-TCDD 1,2,3,7,8-PeCDD 1,2,3,4,7,8-HxCDD 1,2,3,6,7,8-HxCDD 1,2,3,7,8,9-HxCDD 1,2,3,4,6,7,8-HpCDD OCDD 2,3,7,8-TCDF 1,2,3,7,8-PeCDF 2,3,4,7,8-PeCDF 1,2,3,4,7,8-HxCDF 1,2,3,6,7,8-HxCDF 2,3,4,6,7,8-HxCDF 1,2,3,7,8,9-HxCDF 1,2,3,4,6,7,8-HpCDF 1,2,3,4,7,8,9-HpCDF OCDF TeCDDs PeCDDs HxCDDs HpCDDs TeCDFs
16 Determination of WHO-12 PCBs in DX-3 certified reference sediment using the Dioxin Prep System Florisil Version ng / g Certified values (ng / g) DX-3 Replicate 1 (ng / g) DX-3 Replicate 2 (ng / g) DX-3 Replicate 3 (ng / g) DX-3 Replicate 4 (ng / g) PeCB 105 PeCB 114 PeCB 118 PeCB 123 HxCB 156 HxCB 157 HxCB 167 HpCB 189 TeCB 77 TeCB 81 PeCB 126 HxCB
17 Determination of non dioxin-like PCBs in DX-3 certified reference sediment using the Dioxin Prep System - Florisil Version ng / g Information values (ng/g) DX-3 concentrations (ng/g) [Replicate 1] DX-3 concentrations (ng/g) [Replicate 2] DX-3 concentrations (ng/g) [Replicate 3] DX-3 concentrations (ng/g) [Replicate 4] TrCB 28 TePCB 52 PeCB 101 HxCB 153 HxCB 138 HpCB 180 HxCB 149 OcCB 194 OcCB 202 OcCB 205 NoCB 206 NoCB 208 DeCB
18 13C-PeCB 81 13C-PeCB C-PeCB 169 Typical recoveries of 13 C 12 labelled PCDD/Fs and PCBs using the Dioxin Prep System - Florisil Version C-PeCB 77 % DX-3 Replicate 1 (%) DX-3 Replicate 2 (%) DX-3 Replicate 3 (%) DX-3 Replicate 4 (%) 13C-2,3,7,8-TCDD 13C-1,2,3,7,8-PeCDD 13C-1,2,3,6,7,8-HxCDD 13C-1,2,3,4,6,7,8-HpCDD 13C-OCDD 13C-2,3,7,8-TCDF 13C-1,2,3,7,8-PeCDF 13C-1,2,3,6,7,8-HxCDF 13C-1,2,3,4,6,7,8-HpCDF 13C-PeCB C-PeCB C-PeCB C-PeCB C-PeCB C-PeCB C-PeCB C-PeCB 189
19 Fish tissue (WMF-01, Wellington Laboratories) and sandy soil (CRM 529, Supelco) Validation data using the Dioxin Prep System - Florisil Version ng / kg ng / kg ,3,7,8-TCDD 1,2,3,7,8- PeCDD 1,2,3,6,7,8- HxCDD 2,3,4,7,8- PeCDF PeCB 105 PeCB 114 PeCB 118 PeCB 123 HxCB 156 HxCB 157 HxCB 167 HpCB 189 TeCB 77 TeCB 81 PeCB 126 HxCB 169 WMF-01 Fish Tissue - PCDD/F data WMF-01 Fish Tissue - PCB data Certified values (ng / kg) WMF-01 Replicate 1 (ng / kg) WMF-01 Replicate 2 (ng / kg) WMF-01 Replicate 3 (ng / kg) WMF-01 Replicate 4 (ng / kg) Soil CRM PCDD/F data ng / kg Certified values (ng / kg) CRM529 Replicate 1 (ng / kg) CRM529 Replicate 2 (ng / kg) CRM529 Replicate 3 (ng / kg) CRM529 Replicate 4 (ng / kg) ,3,7,8-TCDD 1,2,3,7,8-PeCDD 1,2,3,4,7,8-HxCDD 1,2,3,6,7,8-HxCDD 1,2,3,7,8,9-HxCDD 2,3,7,8-TCDF 1,2,3,7,8-PeCDF 2,3,4,7,8-PeCDF 1,2,3,4,7,8-HxCDF 1,2,3,6,7,8-HxCDF 2,3,4,6,7,8-HxCDF 1,2,3,7,8,9-HxCDF
20 Sample throughput at Trace Organic Analysis Laboratory (Corus) using the Supelco Dioxin Prep System Florisil Version 1 fully trained technician / 9 samples Extraction and concentration (ASE 200) = 1 to 2 days Multi-layer silica clean-up + Florisil = 1 day Basic Alumina step = 1 day PCBs Analysis overnight Data processing = 1 day PCDD/Fs Analysis overnight Data processing = 1 day PCDD/Fs : 3 to 4 working days PCBs : 4 to 5 working days No additional tasks (column packing and activation) 20
21 Acknowledgements Shelley Richardson Corus R, D & T Laurent Ragava, Florian Mure University of Aix-Marseille III, France Rasika Fernando University of Sheffield Sue and Katie Hall Analytical Laboratories 21
DEVELOPMENT OF A SAMPLE PREPARATION SYSTEM FOR DIOXINS: APPLICATION TO IMMUNOASSAY
DEVELOPMENT OF A SAMPLE PREPARATION SYSTEM FOR DIOXINS: APPLICATION TO IMMUNOASSAY Hiroyuki Fujita 1, Noriaki Hamada 2, Kazuyuki Sawadaishi 3, Katsuhisa Honda 1 1 Environmental Science for Industry, Ehime
More informationApplicationNOTE ULTRA TRACE ANALYSIS OF DIOXINS AND FURANS IN HUMAN ADIPOSE TISSUE USING SFE-LC EXTRACTION/CLEANUP AND THE WATERS AUTOSPEC ULTIMA NT
Introduction Legislative limits for dioxins and furans are ever decreasing 1, providing a greater challenge for the dioxin analyst. The extraction and clean-up processes used by the analyst can be imperative
More informationEvaluation of New Dual-Layer Carbon Reversible Column in Analysis of PCDDs/PCDFs and Co-Planar PCBs
Evaluation of New Dual-Layer Carbon Reversible Column in Analysis of PCDDs/PCDFs and Co-Planar PCBs Yukihiro Nishimura, Masaji Yoshida, Mikihiro Kawabata, Atsushi Maemura, Koji Funakoshi, Katsuya Higuchi,
More informationOptimization of pressurized liquid extraction (PLE) of dioxin-furans and dioxin-like PCBs from environmental samples
Available online at www.sciencedirect.com Talanta 75 (2008) 916 925 Optimization of pressurized liquid extraction (PLE) of dioxin-furans and dioxin-like PCBs from environmental samples Pedro Antunes a,
More informationFundamentals of the Method for Analysis of Dioxins/Furans in Method 0010/0023A Train Samples
Fundamentals of the Method for Analysis of Dioxins/Furans in Method 0010/0023A Train Samples Method 0023A Train Configuration for Dioxins and Furans The train configuration of the Method 0023A sampling
More informationValidation of GC-MS/MS for Detection and Confirmation of Low-Level Dioxins
Validation of GC-MS/MS for Detection and Confirmation of Low-Level Dioxins Cristian Cojocariu, 1 Paul Silcock, 1 and Alexander Kotz 2 1 Thermo Fisher Scientific, Runcorn, U.K. 2 European Union Reference
More informationMASS BALANCE APPROACHES TO DIOXIN EXPOSURES IN A MICHIGAN RIVER, USA
MASS BALANCE APPROACHES TO DIOXIN EXPOSURES IN A MICHIGAN RIVER, USA John P. Giesy 1, K. Hilscherova 1, K. Kannan 1, P. Bradley 1, N. Yamashita 2, J. McCabe 3 & A. Taylor 3 1 Michigan State University,
More informationDioxin, PCB analysis in fishmeal Comparison of two extraction techniques
Dioxin, PCB analysis in fishmeal Comparison of two extraction techniques Abstract For the extraction of dioxins and PCBs from fish and derived products such as fish meal quite often classical soxhlet extraction
More informationTechnical Report. Abstract: Pu Wang 1, Huizhong Sun 1, Qinghua Zhang 1, Feifei Tian 2, Lei Cao 2
C46-E299 Technical Report Determination of Polychlorinated Dibenzo-p-dioxins and Dibenzofurans (PCDD/Fs) in Foodstuffs and Animal Feed Using a Triple Quadrupole GCMS-TQ8040 System with Smart MRM Transforms
More informationDioxins & PCBs concerns
Dioxins & PCBs concerns Properties, Sources and Formation RIGHT S O L U T I O N S RIGHT PARTNER Program Introduction to dioxins and PCBs Sources and formation Fate in environmental media Exposure pathways
More informationGC/MS/MS Dioxin and Dioxin-like PCBs in Feed and Food. Jessica Westland, LSAG Applications Chemist
GC/MS/MS Dioxin and Dioxin-like PCBs in Feed and Food Jessica Westland, LSAG Applications Chemist What is a Dioxin? The term dioxins refers to a group of chemically and structurally related halogenated
More informationDioxin & PCB Analysis
Dibenzo-p-dioxins, Dibenzofurans, Polychlorinated Biphenyls Sample Clean up GC Analysis Air Monitoring Resins Solvents 2 Introduction Introduction Figure 1. Dioxin / Furan skeletal structure, can be chlorinated
More informationDioxin & PCB Analysis
Dibenzo-p-dioxins, Dibenzofurans, Polychlorinated Biphenyls Sample Clean up GC Analysis Air Monitoring Resins Solvents 2 Introduction Introduction Figure 1. Dioxin / Furan skeletal structure, can be chlorinated
More informationThe Truth About Dioxin Analysis: Using High Resolution GC-TOFMS and GCxGC-TOFMS to. Analytical Approaches
The Truth About Dioxin Analysis: Using High Resolution GC-TOFMS and GCxGC-TOFMS to Uncover the Pollutants Ignored by Targeted Analytical Approaches Peter Gorst-Allman 1, Jack Cochran 2, Jayne de Vos 3
More informationMeasurements of Household Dust Concentrations of PCDDs, PCDFs, and PCBs from a Community in Michigan, USA. Lynn Zwica, MS
Measurements of Household Dust Concentrations of PCDDs, PCDFs, and PCBs from a Community in Michigan, USA Lynn Zwica, MS The University of Michigan Dioxin Exposure Study The University of Michigan, Ann
More information1.0 INTRODUCTION AND BACKGROUND
REVISED SUPPLEMENTAL INFORMATION ON POLYCHLORINATED DIOXINS AND FURANS (PCDD/F) FOR USE IN PREPARING A QUALITY ASSURANCE PROJECT PLAN (QAPP) November 8, 2010 1.0 INTRODUCTION AND BACKGROUND This document
More informationChapter 3: Development of a PTV-LVI-GC-MS/MS method
3 Development of a programmed temperature vaporizerlarge volume injection-gas chromatography-ion trap MS/MS (PTV-LVI -GC-Ion trap MS/MS) method for dioxins and furans in food and feed 3.1 Summary The potential
More informationQuantitative Determination of Dioxins in Drinking Water by Isotope Dilution using Triple Quadrupole GC-MS/MS
PO-CON1646E Quantitative Determination of Dioxins in Drinking Water by Isotope Dilution using Triple Quadrupole GC-MS/MS ASMS 2016 ThP 152 Jackie, Chiew Mei Chong, Hui Xian Crystal Yeong, Cynthia Melanie
More informationCare and Use Manual for Supelco Multi-Layer Silica Gel Column and Dual-Layer Carbon Reversible Column
This Data Sheet Contains Important Information About The Product. Care and Use Manual for Supelco Multi-Layer Silica Gel Column and Dual-Layer Carbon Reversible Column Contents The Supelco Dioxin Prep
More informationT H E ANA LYSIS O F DIOX INS AND F U R A NS USING H RG C- H IG H R E SO LU T IO N MS W IT H T H E AU T OS P EC- ULTIMA NT
[ application note ] T H E ANA LYSIS O F DIOX INS AND F U R A NS USING H RG C- H IG H R E SO LU T IO N MS W IT H T H E AU T OS P EC- ULTIMA NT Keith Worrall, Anthony Newton and Ramesh Rao, Waters Corporation,
More informationL 364/32 Official Journal of the European Union
L 364/32 Official Journal of the European Union 20.12.2006 COMMISSION REGULATION (EC) No 1883/2006 of 19 December 2006 laying down methods of sampling and analysis for the official control of levels of
More informationONE STEP CLOSER TO A COOK BOOK METHOD FOR DIOXIN ANALYSIS PART 2: ANALYSIS OF FOOD SAMPLES
ONE STEP CLOSER TO A COOK BOOK METHOD FOR DIOXIN ANALYSIS PART 2: ANALYSIS OF FOOD SAMPLES Patterson, Donald G. Jr 1, Shirkhan, Hamid 2, Sadeghi, Kambiz 2,Germansderfer, Phil-M 2, Focant, Jean-Francois
More informationThe following revisions are being implemented for the PCDD/F Supplemental QAPP:
Final DMMP CLARIFICATION PAPER POLYCHLORINATED DIOXINS AND FURANS (PCDD/F): REVISIONS TO THE SUPPLEMENTAL QUALITY ASSURANCE PROJECT PLAN (SQAPP) Prepared by: Erika Hoffman (U.S. Environmental Protection
More informationChemical Characterization of Polychlorinated Biphenyls, -Dibenzo-p-Dioxins, and -Dibenzofurans in Technical Kanechlor PCB Formulations in Japan
Arch. Environ. Contam. Toxicol. 49, 385 395 (2005) DOI: 10.1007/s00244-004-0209-7 Chemical Characterization of Polychlorinated Biphenyls, -Dibenzo-p-Dioxins, and -Dibenzofurans in Technical Kanechlor PCB
More informationDUST DIOXIN CONCENTRATIONS:
DUST DIOXIN CONCENTRATIONS: Wightd TEQ DF17-1998 by rgion Sampl Typ: dust Nots: TEQ DF17-1998 is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs TEQ DF17-1998 (ppt)
More informationOfficial Journal of the European Union REGULATIONS
L 115/22 REGULATIONS COMMISSION REGULATION (EU) 2017/771 of 3 May 2017 amending Regulation (EC) No 152/2009 as regards the methods for the determination of the levels of dioxins and polychlorinated biphenyls
More informationThe Analysis of Dioxins and Dioxin-Like Compounds
Ask The Expert Webinar Series The Analysis of Dioxins and Dioxin-Like Compounds Eric Redman Director of Technical Services Outline Introduction to Dioxins and Furans Nomenclature Sources Hazards, Toxicity,
More informationData Glossary. Acceptance criteria - specific limits placed on characteristics of an item, process, or service defined in requirements documents.
Data Glossary The purpose of this data glossary is to provide a reference for terms used in the analytical analysis of polychlorinated biphenyl (PCB) congeners, utilizing high resolution gas chromatography/high
More informationSAS program: SAB_blood_table_figure_TEQ1998_DF Procedure: PROC B Created by: BH Last Update: WC & BH 06/30/2007
BLOOD DIOXIN CONCENTRATIONS: Wightd TEQ DF17-1998 by rgion Nots: TEQ DF17-1998 is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs TEQ DF17-1998 (ppt) Zon N Man S.E.
More informationKalibrering av ny analysmetod: Polyklorerade dibenzo-p-dioxiner (PCDD) och dibenzofuraner (PCDF) och polyklorerade bifenyler (PCBer) i modersmjölk.
Sakrapport till Naturvårdsverkets Miljöövervakning: Kalibrering av ny analysmetod: Polyklorerade dibenzo-p-dioxiner (PCDD) och dibenzofuraner (PCDF) och polyklorerade bifenyler (PCBer) i modersmjölk. Avtalsnummer:
More informationseparation of the cleaned extract in subgroups of compounds (PCDDs, PCDFs, PCBs) depending on their polarity and geometry. The fractions can then be a
ONE STEP CLOSER TO A COOK BOOK METHOD FOR DIOXIN ANALYSIS PART 1: THE PROCEDURE Focant JF 1, Shirkhan H 2, Patterson Jr DG 3 1 CART, Organic and Biological Analytical Chemistry, Mass Spectrometry Laboratory,
More informationMobilisation of soil-bound dioxins at an old sawmill area.
Mobilisation of soil-bound dioxins at an old sawmill area. Impact of excavation on groundwater levels of PCDF/PCDDs at Norrbyskär. Daniel Larsson Daniel Larsson Master Thesis 45 ECTS Report passed: 12th
More informationFrank L. Dorman The Pennsylvania State University Department of Biochemistry and Molecular Biology
Frank L. Dorman The Pennsylvania State University Department of Biochemistry and Molecular Biology Coauthors and Collaborators Jack Cochran, Shawn Reese Restek Corporation Eric Reiner, Karen Macpherson,
More informationLEVELS IN SOIL AND WATER. Richard Wenning 1, Andrea Von Burg 1, Linda Martello 1, John Pekala 1, Martha Maier 2, William Luksemburg 2.
LEVELS OF POLYCHLORINATED DIBENZO-P-DIOXINS (PCDDS), DIBENZOFURANS (PCDFS), AND POLYCHLORINATED BIPHENYLS (PCBS) IN THE HACKENSACK RIVER AND NEWARK BAY, NEW JERSEY USA Richard Wenning 1, Andrea Von Burg
More informationChain of Custody and Supporting Documentation
Chain of Custody and Supporting Documentation 4 5 6 7 8 9 10 11 12 13 14 15 33 Page 6 34 Page 7 35 Page 8 36 Page 9 37 Page 10 38 Page 11 Table of Contents Case Narrative... 1 Chain of Custody and Supporting
More informationMETHOD 23 DETERMINATION OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS FROM STATIONARY SOURCES. 1. Applicability and Principle
While we have taken steps to ensure the accuracy of this Internet version of the document, it is not the official version. Please refer to the official version in the FR publication, which appears on the
More informationENV455 Hazardous Waste Management
Hazardous Waste ENV455 Hazardous Waste Management Definition of Hazardous Waste and Hazardous Waste Management, Waste Hierarchy, Hazardous Organic Chemicals Özgür ZEYDAN (Phd.) http://cevre.beun.edu.tr/zeydan/
More informationRESULTS FROM THE 8 TH CIRCUIT INTERLABORATORY FOR DIOXINS (CIND)
RESULTS FROM THE 8 TH CIRCUIT INTERLABORATORY FOR DIOXINS (CIND) Raccanelli Stefano and Libralato Simone Consorzio I.N.C.A., VEGA-Edificio Cygnus, Via delle Industrie /8, 3075 Marghera (VE), Italy; Istituto
More informationMEMORANDUM FOR RECORD
CENWS-OD-TS-DM 14 September 2006 MEMORANDUM FOR RECORD SUBJECT: SUPPLEMENTAL DETERMINATION ON THE SUITABILITY OF DREDGED MATERIAL TESTED FOR DIOXIN/FURANS WITHIN THE OLYMPIA HARBOR FEDERAL/PORT NAVIGATION
More informationApplicationNOTE THE ANALYSIS OF POLYCHLORINATED BIPHENYLS (PCBS) BY GC-HIGH RESOLUTION MASS SPECTROMETRY USING THE MICROMASS AUTOSPEC ULTIMA NT
Introduction PCBs (polychlorinated biphenyls) are a class of man-made chemicals first manufactured commercially in the late 1920's and were used primarily as a dielectric fluid in electrical equipment.
More informationMETHOD 8290A 1.0 SCOPE AND APPLICATION
METHOD 8290A POLYCHLORINATED DIBENZODIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS (PCDFs) BY HIGH-RESOLUTION GAS CHROMATOGRAPHY/HIGH- RESOLUTION MASS SPECTROMETRY (HRGC/HRMS) 1.0 SCOPE AND APPLICATION
More information2.1 All differences between Method 1613B and actual laboratory techniques have been developed to reduce interferences and increase sensitivity.
1. PURPOSE 1.1 This procedure describes the preparation and analytical techniques used for the analysis of samples for polychlorinated dibenzodioxin and furans (PCDD/PCDF) by EPA Method 1613B. 2. SCOPE
More information~~LABORATORY DATA CONSULTANTS, INC.
~~LABORATORY DATA CONSULTANTS, NC. :,,, 2701 Loker Ave. West, Suite 220, Carlsbad, CA 92010 Bus: 760-827-1100 Fax: 760-827-1099 LC>C:: Anchor Environmental, LLC 720 Olive Way, Suite 1900 Seattle, WA 98101
More informationInside the Black Box of an Environmental Testing Laboratory Basic Analytical Procedures
Ask The Expert Webinar Series Inside the Black Box of an Environmental Testing Laboratory Basic Analytical Procedures Karla Buechler Corporate Technical Director Outline of Environmental Analysis Part
More informationPhytoremediation assisted by arbuscular mycorrhizal fungi to clean-up dioxins/furans polluted soil of the Halluin site?
Phytoremedition ssisted by rbusculr mycorrhizl fungi to clen-up dioxins/furns polluted soil of the Hlluin site? Hcène MEGLOULI Joël FONTAINE & Aniss LOUNES-HADJ SAHRAOUI Unité de Chimie Environnementle
More informationContinuous Fractionation of Fly Ash Particles by SPLITT for the Investigation of PCDD/Fs Levels in Different Sizes of Insoluble Particles
Environ. Sci. Technol. 2002, 36, 4416-4423 Continuous Fractionation of Fly Ash Particles by SPLITT for the Investigation of PCDD/Fs Levels in Different Sizes of Insoluble Particles MYEONG HEE MOON, DUKJIN
More informationGas Chromatography Mass Spectrometry (GCMS)
Gas Chromatography Mass Spectrometry (GCMS) Organics Chlorinated pesticides DDT Chlordanes Polychlorinated biphenyls (PCBs) Polyaromatic hydrocarbons (PAHs) DDT (Dichlorodiphenyl-trichloroethane) Used
More informationEffects of inorganic chlorine source on dioxin formation using fly ash from a fluidized bed incinerator
Journal of Environmental Sciences 19(2007) 756 761 Effects of inorganic chlorine source on dioxin formation using fly ash from a fluidized bed incinerator LU Sheng-yong 1, YAN Jian-hua 1,, LI Xiao-dong
More informationAccelerated Solvent Extraction GC-MS Analysis and Detection of Polycyclic Aromatic Hydrocarbons in Soil
Accelerated Solvent Extraction GC-MS Analysis and Detection of Polycyclic Aromatic Hydrocarbons in Soil Che Jinshui, 1 Deng Guifeng, 1 Liang Lina, 1 and Aaron Kettle, 2 1 Thermo Fisher Scientific (China)
More informationPosterReprint INTRODUCTION
INTRODUCTION 'Dioxins' refers to a group of chemical compounds that share certain similar chemical structures and biological characteristics. Several hundred of these toxic compounds exist and are members
More informationMETHOD 8280 THE ANALYSIS OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS
METHOD 8280 THE ANALYSIS OF POLYCHLORINATED DIBENZO-P-DIOXINS AND POLYCHLORINATED DIBENZOFURANS 1.0 SCOPE AND APPLICATION 1.1 This method is appropriate for the determination of tetra-, penta-, hexa-,
More informationPutting the Pieces of the Puzzle Together. By Kim Kirkland, Methods Team Leader EPA s Office of Resource Conservation and Recovery
Putting the Pieces of the Puzzle Together By Kim Kirkland, Methods Team Leader EPA s Office of Resource Conservation and Recovery Topics to Be Covered Item 1 Brief Review of Current Method Team Projects
More informationCALIBRATION OF GC/MS METHOD AND VALIDATION OF THE MODIFIED SAMPLE PREPARATION FOR DETERMINATION OF POLYCYCLIC AROMATIC HYDROCARBONS
Journal Ivan of Givechev, Chemical Dancho Technology Danalev, and Spaska Metallurgy, Yaneva, 53, Dimitar 4, 2018, Tanev 717-724 CALIBRATION OF GC/MS METHOD AND VALIDATION OF THE MODIFIED SAMPLE PREPARATION
More informationCOMMON IMPLEMENTATION STRATEGY FOR THE WATER FRAMEWORK DIRECTIVE (2000/60/EC)
Technical Report - 2014-084 COMMON IMPLEMENTATION STRATEGY FOR THE WATER FRAMEWORK DIRECTIVE (2000/60/EC) Guidance Document No. 33 ON ANALYTICAL METHODS FOR BIOTA MONITORING UNDER THE WATER FRAMEWORK DIRECTIVE
More informationMass spectrometric approach for the analysis of polychlorinated dibenzop-dioxins. and dibenzofurans in stack gas emissions by gas
1 2 3 4 Mass spectrometric approach for the analysis of polychlorinated dibenzop-dioxins and dibenzofurans in stack gas emissions by gas chromatography coupled to triple-quadrupole mass spectrometry using
More informationAdvances in the Analysis of Dioxin and Environmental Toxicants
Advances in the Analysis of Dioxin and Environmental Toxicants Co-Authors Eric Reiner, Terry Kolic, Karen MacPherson, Sheng Yang, Alina Muscalu, Adrienne Boden, Karl Jobst, Patrick Crozier, Vin Khurana,
More informationMETHOD Compound Name CAS No a
METHOD 8290 POLYCHLORINATED DIBENZODIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS (PCDFs)BY HIGH-RESOLUTION GAS CHROMATOGRAPHY/HIGH-RESOLUTION MASS SPECTROMETRY (HRGC/HRMS) 1.0 SCOPE AND APPLICATION
More informationUsing Magnetic Sector GC-HRMS in a Commercial Dioxin Lab
An Executive Summary Using Magnetic Sector GC-HRMS in a Commercial Dioxin Lab David Hope Chief Executive Officer Pacific Rim Laboratories Introduction Persistent organic pollutants (POPs) are toxic chemicals
More informationHRMS PBDE Analysis on a Thermo DFS. Dave Hope, Pacific Rim Laboratories Inc
HRMS PBDE Analysis on a Thermo DFS Dave Hope, Pacific Rim Laboratories Inc Outline PBDE what is it and why are we interested in it EPA 1614 HRMS analysis Considerations for Thermo DFS / Trace GC Food analysis
More informationMETHOD 8280B 1.0 SCOPE AND APPLICATION
METHOD 8280B POLYCHLORINATED DIBENZO-p-DIOXINS (PCDDs) AND POLYCHLORINATED DIBENZOFURANS (PCDFs) BY HIGH-RESOLUTION GAS CHROMATOGRAPHY/ LOW-RESOLUTION MASS SPECTROMETRY (HRGC/LRMS) SW-846 is not intended
More informationFindings of the Fiscal 2000 Survey on Brominated Dioxins
Findings of the Fiscal 2000 Survey on Brominated Dioxins November 30, 2001 (Fri.) Office of Environmental Risk Assessment, Environmental Health Department, Ministry of the Environment Yukio Suzuki, Director
More informationResultatrapport för projektet: Screening av humanvävnad
Rapport till Naturvårdsverket Programområde Miljögiftssamordning Screening Resultatrapport för projektet: Screening av humanvävnad Kontrakt nr 219 0603, dnr 721-1610-06Mm Ingrid Ericson, Bert van Bavel
More informationMETHOD 3600B CLEANUP
METHOD 3600B CLEANUP 1.0 SCOPE AND APPLICATION 1.1 Method 3600 provides general guidance on selection of cleanup methods that are appropriate for the target analytes of interest. Cleanup methods are applied
More informationReceived 24 October 2002; received in revised form 3 April 2003; accepted 3 April 2003
Journal of Chromatography A, 998 (003) 169 181 www.elsevier.com/ locate/ chroma New strategy for comprehensive analysis of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins, polychlorinated
More informationSchedule. Draft Section of Lab Report Monday 6pm (Jan 27) Summary of Paper 2 Monday 2pm (Feb 3)
Schedule Assignment Due Date Draft Section of Lab Report Monday 6pm (Jan 27) Quiz for Lab 2 Peer Review of Draft Complete Lab Report 1 Tuesday 9:30am Wednesday 6pm Friday 6pm Summary of Paper 2 Monday
More informationEvaluation of Several Columns and Solvents for Post-Extraction Gel Permeation Chromatography (GPC) Clean-up of Fish Tissue Prior to PCB Analysis
Evaluation of Several Columns and Solvents for Post-Extraction Gel Permeation Chromatography (GPC) Clean-up of Fish Tissue Prior to PCB Analysis Keywords: Automated GX-271 GPC Clean-up System, Contaminants,
More informationApplicationNOTE A STUDY OF THE ANALYSIS OF POLYBROMINATED DIPHENYL ETHER FLAME RETARDANTS BY GC/MS/MS. Introduction. Materials and Methods
Abstract The development of a GC/MS/MS method for the analysis of brominated flame retardants will be presented. Standard methods require the use of high resolution magnetic sector instrumentation, which
More informationHORIZONTAL STANDARDISATION FOR SOIL, SEDIMENT, SLUDGE AND BIO-WASTE
Oktober 2004 HORIZONTAL - and DL-PCB HORIZONTAL STANDARDISATION FOR SOIL, SEDIMENT, SLUDGE AND BIO-WASTE Report of the final desk study on the determination of and DL-PCB for the European project HORIZONTAL
More informationVerification and Review of Data for Chlorinated Dioxins, Furans and PCB Congeners by Isotope Dilution HRGC/ HRMS
Verification and Review of Data for Chlorinated Dioxins, Furans and PCB Congeners by Isotope Dilution HRGC/ HRMS Presented By: Charles Appleby Office of Superfund Remediation and Technology Innovation
More informationJo Marie Cook Bureau of Chemical Residue Laboratories
Jo Marie Cook Bureau of Chemical Residue Laboratories Incident Command Do as your told! Wait and see not on our shores! Yet! Follow FDA lead Hesitation to spend $$$ FERN and ccap activation Bring up NOAA
More informationChemosphere xxx (2011) xxx xxx. Contents lists available at ScienceDirect. Chemosphere. journal homepage:
Chemosphere xxx (2011) xxx xxx Contents lists available at ScienceDirect Chemosphere journal homepage: www.elsevier.com/locate/chemosphere Comprehensive two-dimensional gas chromatography time of flight
More informationEdward Ming-Yang Wu 1, Lin-Chi Wang 2*, Sheng-Lun Lin 3,4, Guo-Ping Chang-Chien 4,5
Aerosol and Air Quality Research, 14: 185 196, 2014 Copyright Taiwan Association for Aerosol Research ISSN: 1680-8584 print / 2071-1409 online doi: 10.4209/aaqr.2013.09.0285 Validation and Characterization
More informationAPPENDIX K. Fingerprinting Justification Memo
APPENDIX K Fingerprinting Justification Memo TECHNICAL MEMORANDUM Oakland Bay Sediment Investigation Potential for Fingerprinting Analysis using Sediment Data April 2009 Prepared for Washington Department
More informationMethod 23 - Determination of Polychlorinated Dibenzo-p-dioxins and Polychlorinated Dibenzofurans from Municipal Waste Combustors
Method 23 - Determination of Polychlorinated Dibenzo-p-dioxins and Polychlorinated Dibenzofurans from Municipal Waste Combustors 1. APPLICABILITY AND PRINCIPLE 1.1 Applicability. This method is applicable
More informationAmbient air concentrations of PCDD/Fs, coplanar PCBs, PBDD/Fs, and PBDEs and their impacts on vegetation and soil
Int. J. Environ. Sci. Technol. (215) 12:2997 38 DOI 1.17/s13762-14-692-y ORIGINAL PAPER Ambient air concentrations of PCDD/Fs, coplanar PCBs, PBDD/Fs, and PBDEs and their impacts on vegetation and soil
More information(CATION EXCHANGE AND LN RESIN, WITH VACUUM BOX SYSTEM)
Analytical Procedure RADIUM IN WATER (CATION EXCHANGE AND LN RESIN, WITH VACUUM BOX SYSTEM) 1. SCOPE 1.1. This is a method for separation and measurement of radium-226 and radium-228 in water. This method
More informationCSO/SWO Data Validation Reports June 20, 2014
CSO/SWO Data Validation Reports June 20, 2014 Transmitted Via Email June 20, 2014 U.S. Environmental Protection Agency, Region II Emergency and Remedial Response Division 290 Broadway, 19 th Floor, Room
More informationU.S. Army Corps of Engineers
U.S. Army Corps of Engineers New England District Concord, Massachusetts QUALITY ASSURANCE PROJECT PLAN Volume III Appendices B, C, D 8 January 1999 (DCN: GEP2-123098-AAET) Revised May 2003 (DCN: GE-022803-ABLZ)
More informationTECHNETIUM-99 IN WATER
Analytical Procedure TECHNETIUM-99 IN WATER (WITH VACUUM BOX SYSTEM) 1. SCOPE 1.1. This procedure describes a method to separate and measure technetium-99 in water. 1.2. This method does not address all
More informationMETHOD 3600C CLEANUP
METHOD 3600C CLEANUP 1.0 SCOPE AND APPLICATION 1.1 Method 3600 provides general guidance on selection of cleanup methods that are appropriate for the target analytes of interest. Cleanup methods are applied
More informationEstimation of LOQ for the Analysis of Persistent Organic Pollutants, in particular PCDD/Fs and PCBs
38th International Symposium on Halogenated Persistent Organic Pollutants (POPs) Thermo User Meeting - DFS Magnetic Sector GC-HRMS Krakow, August 26 31, 2018 Estimation of LOQ for the Analysis of Persistent
More informationTSNAs in Tobacco Filler and Cigarette Smoke
TSNAs in Tobacco Filler and Cigarette Smoke Chris Wright Carol Goss Magdalena Minnion British American Tobacco Group R&D UK US FDA Center for Tobacco Products Scientific Workshop 30-31 July 2013 1 A. Describe
More informationHealth Consultation. Dioxin and Polycyclic Aromatic Hydrocarbon chemical signatures (fingerprints) in sediments
Health Consultation Dioxin and Polycyclic Aromatic Hydrocarbon chemical signatures (fingerprints) in sediments ST. LOUIS RIVER SEDIMENTS: US STEEL SITE DULUTH, ST. LOUIS COUNTY, MINNESOTA EPA FACILITY
More informationThe Role of Proficiency Tests in the Estimation of Measurement Uncertainty of PCDD/PCDF and PCB Determination by Isotope Dilution Methods
The Role of Proficiency Tests in the Estimation of Measurement Uncertainty of PCDD/PCDF and PCB Determination by Isotope Dilution Methods e-mail: stefano@raccanelli.eu Stefano Raccanelli, Environmental
More informationGUIDELINES FOR THE ENVIRONMENTAL MONITORING AND IMPACT ASSESSMENT ASSOCIATED WITH SUBSEA OIL RELEASES AND DISPERSANT USE IN UK WATERS.
Technical Guideline No. 08 Processing and analysis of water, biota and sediment samples for the determination of hydrocarbon contamination using gas chromatography -mass spectrometry Robin Law 2014 To
More informationAnalyzing PCBs in Source Materials and Environmental Media: Soil, Water and Air. Jim Occhhialini Jim Okun Patricia McIsaac
Analyzing PCBs in Source Materials and Environmental Media: Soil, Water and Air Jim Occhhialini Jim Okun Patricia McIsaac Agenda Background Information Analytical Methodology Options for Analytical Support
More informationThe relationship between fly ash chemistry and the thermal formation of polychlorinated pollutants during waste incineration
The relationship between fly ash chemistry and the thermal formation of polychlorinated pollutants during waste incineration Phan Dương Ngọc Châu Department of Chemistry Umeå University Doctoral thesis
More informationProject "Dioxins : contamination and biodegradation" Catherine Rafin, ULCO, UCEIV Dunkerque Joël Fontaine, ULCO, UCEIV Calais
Project "Dioxins : contamination and biodegradation" Catherine Rafin, ULCO, UCEIV Dunkerque Joël Fontaine, ULCO, UCEIV Calais Thursday March 28, 2013 1 Introduction Aims - Deepen the knowledge on dioxins
More informationby PSP Volume 15 No Fresenius Environmental Bulletin
by PSP Volume 5 No. 6 Fresenius Environmental Bulletin THE EFFECT OF AGE ON THE CONCENTRATION OF POLY- CHLORINATED DIBENZO-P-DIOXINS, DIBENZOFURANS AND DIOXIN-LIKE POLYCHLORINATED BIPHENYLS IN BALTIC HERRING
More information95 th Percentiles for Blood and Urine Levels of Chemicals Measured in the Report
95 th Percentiles for and Levels of s Measured in the Report The data summarized here provide 95 th percentile levels for these 148 chemicals by age, sex, and race or ethnicity in NHANES 2001-2002. Scientists
More informationHiroyuki FUJITA 1 *, Takanori MAKINO1, Kenji INABA 1, Kazuki YAMAMOTO 2
PAP2348_No14 Hiroyuki FUJITA 1 *, Takanori MAKINO1, Kenji INABA 1, Kazuki YAMAMOTO 2 1: MIURA CO., LTD., 864-1, Hojotsuji, Matsuyama, Ehime, 799-243, JAPAN; 2: Ehime University, 3-5-7, Tarumi, Matsuyama,
More informationThe Practicality (Necessity) of Use of Clean-up Techniques for the Analysis of D/F and PCB Congeners
The Practicality (Necessity) of Use of Clean-up Techniques for the Analysis of D/F and PCB Congeners Charles Neslund, Scientific Officer, Eurofins Lancaster Laboratories Environmental, LLC National Environmental
More informationDevelopment of Environmental Analysis Methods Using Supercritical Fluid Extraction and Supercritical Fluid Chromatography
Focusing Review Development of Environmental Analysis Methods Using Supercritical Fluid Extraction and Supercritical Fluid Chromatography National Metrology Institute of Japan (NMIJ), National Institute
More informationDioxins and PCBs in solid matter from the River Elbe, its tributaries and the North Sea (longitudinal profile, 2008)
Dioxins and PCBs in solid matter from the River Elbe, its tributaries and the North Sea (longitudinal profile, 2008) Gunther Umlauf, Burkhard Stachel, Giulio Mariani, and Rainer Götz EUR 24766 EN - 2011
More informationMicrowave Extraction Provides More Reliable Analysis of High Mass Unit Additives
Microwave Extraction Provides More Reliable Analysis of High Mass Unit Additives Alex Kovalenko GC/MS Scientist Brian Bacher Technical Service NSL Analytical Services, Inc. Cleveland, Ohio Shortly after
More informationMETHOD 8100 POLYNUCLEAR AROMATIC HYDROCARBONS
METHOD 8100 POLYNUCLEAR AROMATIC HYDROCARBONS 1.0 SCOPE AND APPLICATION 1.1 Method 8100 is used to determine the concentration of certain polynuclear aromatic hydrocarbons (PAH). Table 1 indicates compounds
More informationNew certified and candidate certified reference materials for the analysis of PCBs, PCDD/Fs, OCPs and BFRs in the environment and food
New certified and candidate certified reference materials for the analysis of PCBs, PCDD/Fs, OCPs and BFRs in the environment and food S.P.J. van Leeuwen, R. Van Cleuvenbergen, M. Abalos, A.-L. Pasini,
More informationMETHOD 3545A PRESSURIZED FLUID EXTRACTION (PFE)
METHOD 3545A PRESSURIZED FLUID EXTRACTION (PFE) SW-846 is not intended to be an analytical training manual. Therefore, method procedures are written based on the assumption that they will be performed
More informationThermo Scientific TSQ 8000 Evo Triple Quadrupole GC-MS/MS. Expect more productivity. with the evolution of ultimate performance GC-MS/MS
Thermo Scientific TSQ 8 Evo Triple Quadrupole GC-MS/MS Expect more productivity with the evolution of ultimate performance GC-MS/MS Productivity Evolving with the changing laboratory environment The pressure
More informationENVIRONMENTAL analysis
ENVIRONMENTAL analysis Analyzing Wastewater Effluents for PAH s and PBDE s Using the Agilent 7000 Triple Quadrupole GC/MS Solutions for Your Analytical Business Markets and Applications Programs Authors
More information