Chapter 20 Amines 胺类
|
|
|
- Anthony Powers
- 6 years ago
- Views:
Transcription
1 Amines
2 ORGAIC CEMISTRY 20.1 omenclature
3 ORGAIC CEMISTRY Amines are classified as primary (R 2 ), secondary (R 2 ), or tertiary (R 3 ), depending on the number of organic substituents attached to nitrogen. C 3 2 (C 3 ) 2 (C 3 ) 3 Methylamine Dimethylamine Trimethylamine primary secondary tertiary ( ) ( ) ( )
4 ORGAIC CEMISTRY ote When we speak of a tertiary alcohol or alkyl halide, we refer to the degree of substitution at the alkyl carbon atom. When we speak of a tertiary amine, however, we refer to the degree of substitution at the nitrogen atom. C 3 C 3 C 3 C 3 C O C 3 C 3 C 2 C 3 C 3 C 3 tert-butyl alcohol Trimethylamine tert-butylamine (a tertiary alcohol) (a tertiary amine) (a primary amine)
5 ORGAIC CEMISTRY omenclature of Amines Common nomenclature: alkylamines (the suffix -amine is added to the name of the alkyl substituent.) Systematic nomenclature: the name of the parent compound e -amine
6 ORGAIC CEMISTRY C 3 C 2 2 Ethylamine (ethanamine) C 3 Primary Amines C C 3 C 2 2 Isobutylamine (2-methyl-1-propanamine) 2-1- C 3 C 3 C 2 C 3 tert-butylamine (2-methyl-2-propanamine) Cyclohexylamine (cyclohexanamine) 1,4-Butanediamine 1,4-
7 ORGAIC CEMISTRY Secondary and Tertiary Amines Common nomenclature: symmetrical secondary and tertiary amines are named by adding the prefix di- or tri- to the alkyl group. Systematic nomenclature: named as - substituted primary amines. The largest alkyl group is chosen as the parent name, and the other alkyl group are considered -substituents on the parent ( since they re attached to nitrogen).
8 ORGAIC CEMISTRY C 3 C 2 C 3 Ethylmethylamine (-methylethanamine) (C 3 C 2 ) 2 Diethylamine (-ethylethanamine) (C 3 C 2 ) 3 Triethylamine (,-diethylethanamine) - -,- C 3 C 3 C 2 C 2 (C 3 ) 2 C 2 C 3 Dimethylpropylamine (,-Dimethyl-1-propanamine),- -1- Ethylmethylcyclohexylamine (-Ethyl--methylcyclohexanamine) - --
9 ORGAIC CEMISTRY An 2 group, when not the principal group, is named by the prefix amino-. CO 2 2 CO Aminobutanoic acid 2 2,6-Diaminobenzoic acid 2-2,6- O 2 4-Amino-2-butanone C 2 C 2 O 2-Aminoethanol 2-
10 ORGAIC CEMISTRY 20.1A Arylamines Benzenamine 1-aphthalenamine 1,3-benzenediamine C 6 5 -Phenylbenzenamine -Phenyl-2-naphthalenamine
11 ORGAIC CEMISTRY Three common arylamines have the following names: 2 C C 3 OC 3 Aniline -Methylaniline p-toluidine p-anisidine (benzenamine) (-methylbenzenamine) (4-methylbenzenamine) (4-methoxybenzenamine)
12 ORGAIC CEMISTRY 20.1B eterocyclic Amines The important heterocyclic amines all have common names. In systematic replacement nomenclature the prefixes aza-, diaza-, and triaza- are used to indicate that nitrogen atoms have replaced carbon atoms in the corresponding hydrocarbon Pyrrole Pyrazole Imidazole (1-aza-2,4-cyclopentadienepentadienepentadiene) (1,2-diaza-2,4-cyclo- (1,3-diaza-2,4-cyclo- (1- -2,4- ) (1,2- -2,4- ) 4 3
13 ORGAIC CEMISTRY O 1 2 Oxazole (1-oxa-3-aza-2,4-cyclopentadiene) (1,3- -2,4- ) Pyrrolidine (azacyclopentane) ( ) S Thiazole (1-thia-3-aza-2,4-cyclopentadiene) (1,3- -2,4- ) 2 Indole (1-azaindene) (1- )
14 ORGAIC CEMISTRY Pyridine Pyridazine Pyrimidine Pyrazine (azabenzene) (1,2-diazabenzene) (1,3-diazabenzene) ( ) (1,2- ) (1,3- ) (1,3-diazabenzene) (1,3- ) 8 Piperidine Quinoline 6 7 (azacyclohexane) ( ) (1-azanaphthalene) (1- ) Isoquinoline Purine
15 ORGAIC CEMISTRY 20.2 Physical Properties and Structure of Amines
16 ORGAIC CEMISTRY 20.2A Physical Properties Moderately polar substances Boiling points: alcohol > amine > alkane Form strong hydrogen bonds to each other (1 and 2 ) Form hydrogen bonds to water or other hydroxylic solvents. Very water soluble (low molecular weight amines).
17 ORGAIC CEMISTRY 20.2B Structure of Amines sp 3 hybridized R' R" R" R' C 3 C 3 C3 R Interconversion of amine enantiomers R R' R" R R'" R"' R" R' Quaternary ammonium salts such as these can be resolved R
18 ORGAIC CEMISTRY 20.3 Basicity of Amines: Amine Salts
19 ORGAIC CEMISTRY R 2 + O R 2 + O In the gas phase: 3 > 2 > 1 > 3 In aqueous solution: 2 > 1 > 3 > 3
20 ORGAIC CEMISTRY 20.3A Basicity of Arylamines Arylamines are much weaker bases than corresponding nonaromatic amines 2 2 C 3 2 pk a Delocalization of the electron pair stabilizes aniline. 2. Aryl groups are electron-withdrawing groups.
21 1. ORGAIC CEMISTRY 20.3B Amines versus Amides Basicity : nonaromatic amines > arylamines > amides. The pk a of the conjugate acid of a typical amide is about 0. Amide O R C 2 -Protonated Amide O R C 2 O R C 3 O R C 2 O R C 3 Larger resonance stabilization Smaller resonance stabilization 2. The powerful electron-withdrawing effect of the carbonyl group of the amide. O O O R C 2 R C 2 R C 2 Protonated on the oxygen atom
22 ORGAIC CEMISTRY 20.3C Aminium Salts and Quaternary Ammonium Salts ( ) When 1, 2, and 3 amines act as bases and react with acids, they form compounds called aminium salts. Aminium salt + attached to at least one. C 3 C Cl (C 3 C 2 ) 2 + Br (C 3 C 2 ) 3 + I 2 O C3 C 2 3 Cl Ethylaminium chloride 2 O (C3 C 2 ) 2 2 Br Diethylaminium bromide 2 O (C3 C 2 ) 3 3 I Triethylaminium iodide
23 ORGAIC CEMISTRY When + is not attached to a. the compound is called a quaternary ammonium salt. (C 3 C 2 C 2 C 2 ) 4 Br Tetrabutylammonium bromide (TBAB) (a quaternary ammonium salt) Quaternary ammonium hydroxides ( ) are strong bases as strong as ao or KO. (C 3 ) 4 O + Cl (C 3 ) 4 Cl + 2 O
24 ORGAIC CEMISTRY 20.3D Solubility of Amines in Aqueous Acids Almost all alkylaminium chlorides, bromides, iodides and sulfates are soluble in water. Distinguishing amines from nonbasic compounds Separating amines from nonbasic compounds Water-insoluble amine + X X (or 2 SO 4 ) (or SO 4 ) Water-soluble aminium salt Water-insoluble amides do not dissolve in dilute aqueous acid solution.
25 ORGAIC CEMISTRY 20.3E Amines as Resolving Agents Enantiomerically pure amines are often used to resolve racemic form of acidic compounds. aturally occurring optically active amines such as ( )-quinine, ( )-strychnine, and ( )-brucine are often employed as resolving agents for racemic acids. O O ( )-Strychnine C 3 O C 3 O O O ( )-Brucine
26 ORGAIC CEMISTRY 20.4 Some Biologically Important Amines
27 ORGAIC CEMISTRY 2-Phenylethylamines O O C C 2 R O R = C 3, Adrenaline (epinephrine) R =, oradrenaline (norepinephrine) C 2 C C 3 2 Amphetamine (benzendrine) C 2 C 2 2 O C 2 C Phenylethylamine 2 O Dopamine
28 ORGAIC CEMISTRY C 3 O C 3 O RO O O OC 3 Mescaline C 2 C 2 2 C 3 R =, Morphine R = C 3, Codeine O C 3 O C 2 C 2 2 Serotonin 5 O C ( )-Quinine
29 ORGAIC CEMISTRY O Vitamins and Antihistamines( ) C 2 O C 2 O C 2 Cl C 3 S C 2 C 2 O C 3 C 3 2 Pyridoxine Thiamine chloride (vitamin B 6 ) (vitamin B 1 ) C 3 icotine CO 2 icotinic acid (niacin) C 2 C 2 2 istamine
30 ORGAIC CEMISTRY Cl CC 2 C 2 (C 3 ) 2 Chlorpheniramine Tranquilizers ( ) C 3 Cl O Chlordiazepoxide (Librium)
31 ORGAIC CEMISTRY eurotransmitters ( ) O C 3 C OC 2 C 2 (C 3 ) 3 Acetylcholine + 2 O acetylcholinesterase C 3 CO 2 + OC 2 C 2 (C 3 ) 3 Choline
Chapter 20. Amines. Nomenclature for amines. Aryl amines
Nomenclature for amines Chapter 20 Common names are widely used, named as alkylamines Systematic (IUPAC) nomenclature replaces the -e of the corresponding parent alkane with -amine Amines Simple secondary
Lecture Notes Chemistry 342 Mukund P. Sibi Lecture 33 Amines
Lecture otes Chemistry 342 Mukund P. Sibi Amines Amines are organic compounds derived from ammonia. The nitrogen in amines contains a lone pair of electrons. The presence of this lone pair of electrons
Chemistry Chapter 16
Chemistry 2100 Chapter 16 Amines Amines are nitrogen-containing compounds Structure and Classification Amines are classified as 1, 2, or 3 depending on the number of carbon groups bonded to nitrogen. C
All Classes of Organic Compounds
Amines All Classes of Organic Compounds ydrocarbons Functionalized ydrocarbons F,Cl,Br O,S, Alkanes Alkenes Alkynes Aromatics alides -O- -S- -- Alcohols Phenols Ethers Thiols Dissulfides Amines O C O C
Chapter 15 Amines Amines 15.2 Naming Amines 15.3 Physical Properties of Amines
Chapter 15 Amines 15.1 Amines 15.2 Naming Amines 15.3 Physical Properties of Amines 1 Amines Amines are organic compounds in which one or more H in ammonia, NH 3, is replaced with alkyl or aromatic groups.
Ch 16 Amines. Organic and Biochemsity
Ch 16 Amines Organic and Biochemsity Amines Section 16.1 Introduction itrogen found in amine group is the fourth most common element in organic chemistry Known for their basicity Section 16.2 Classification
22.1 Amine Nomenclature
Chapter 22 Amines 22.1 Amine Nomenclature Classification of Amines Alkylamine N attached to alkyl group Arylamine N attached to aryl group Primary, secondary, or tertiary determined by number of carbon
Amines - Derivatives of Ammonia
Amines - Derivatives of Ammonia lassification by the number of attached groups ethylamine diethylamine triethylamine Amines - Derivatives of Ammonia lassification by the type of attached groups 2 2 aromatic
Dr. Mohamed El-Newehy
By Dr. Mohamed El-Newehy Chemistry Department, College of Science, King Saud University http://fac.ksu.edu.sa/melnewehy Amines 1 Classification and Structure of Amines -The relation between ammonia and
Lecture'14:'March'19,'2013
CM'224' 'rganic'chemistry'ii Spring'2013,'Des'Plaines' 'Prof.'Chad'Landrie quinine Lecture'14:'March'19,'2013 Classifica)on,&,omenclature,of,Amines,(24.1) Structure,,Proper)es,,Basicity,,(24.2B24.5) Synthesis,of,Amines,(24.6)
BRCC CHM102 Chapter 16 Notes Class Notes Page 1 of 7 H 3 C N CH 3 CH 3 CHCH 3
BR M102 hapter 16 otes lass otes Page 1 of 7 hapter 16 Amines Amines derivatives of ammonia R 2 primary amine 3 R 1 R 2 secondary amine 3 R 1 R 2 R 3 tertiary amine 3 * Remember that classification of
.. Amines CHAPTER SUMMARY
10 N.. N.. CHAPTER SUMMARY 10.1 Structure of are derivatives of ammonia in which one or more hydrogens have been replaced by organic groups. Replacement of one hydrogen results in a primary amine. In a
Chapter 24. Amines. Based on McMurry s Organic Chemistry, 7 th edition
Chapter 24. Amines Based on McMurry s Organic Chemistry, 7 th edition Amines Organic Nitrogen Compounds Organic derivatives of ammonia, NH 3, Nitrogen atom with a lone pair of electrons, making amines
Chemistry 110. Bettelheim, Brown, Campbell & Farrell. Ninth Edition
hemistry 110 Bettelheim, Brown, ampbell & Farrell inth Edition Introduction to General, rganic and Biochemistry hapter 16 Amines Amine Molecules are Weak Bases Aliphatic & Aromatic Amines Amines are relatives
Amines and Related Nitrogen Compounds
11 Amines and Related itrogen ompounds hapter Summary Amines are organic derivatives of ammonia. They may be primary, secondary, or tertiary, depending on whether one, two, or three organic groups are
Chapter 19: Amines. Introduction
Chapter 19: Amines Chap 19 HW: (be able to name amines); 37, 39, 41, 42, 44, 46, 47, 48, 53-55, 57, 58 Introduction Organic derivatives of ammonia. Many are biologically active. Chap 19: Amines Slide 19-2
CHAPTER 22: Amines R 2 H N N N R 1. cadeverine N CH 3. nicotine
Based on notes by JZ updated 4/2018 Amines are Biologically Important CAPTE 22: Amines Amino acids are the basis of all peptides and proteins. These are the tissue building blocks and nature's catalysts
10. Amines (text )
2009, Department of Chemistry, The University of Western Ontario 10.1 10. Amines (text 10.1 10.6) A. Structure and omenclature Amines are derivatives of ammonia (H 3 ), where one or more H atoms has been
896 Chapter 21 Amines H H N R R R N R H R N R H O H R 3 N CH 2 NH 2 NHCH 3
896 Chapter 21 Amines 21.20 Summary Section 21.1 Section 21.2 Section 21.3 Section 21.4 Alkylamines are compounds of the type shown, where R, R, and R are alkyl groups. ne or more of these groups is an
Amines Reading Study Problems Key Concepts and Skills Lecture Topics: Amines: structure and nomenclature
Amines Reading: Wade chapter 19, sections 19-1-19-19 Study Problems: 19-37, 19-39, 19-40, 19-41, 19-44, 19-46, 19-47, 19-48, 19-51, 19-54 Key Concepts and Skills: Explain how the basicity of amines varies
Benzylamine reacts with nitrous acid to form unstable diazonium salt, which in turn gives alcohol with the evolution of nitrogen gas.
Benzylamine reacts with nitrous acid to form unstable diazonium salt, which in turn gives alcohol with the evolution of nitrogen gas. On the other hand, aniline reacts with HNO2 at a low temperature to
AMINES. 4. From your knowledge of the effects involved, predict or explain experimental results. Important areas include:
AMINES A STUDENT SHOULD BE ABLE TO: 1. Give the IUPAC or common name given the structure, and draw the structure given the name of amines and common nitrogen heterocycles (pyrrole, pyridine, purine, pyrimidine,
Alkylamines are compounds of the type shown, where R, R, and R are alkyl groups. One or more of these groups is an aryl group in arylamines.
22.20 Summary 955 22.20 SUMMARY Section 22.1 Alkylamines are compounds of the type shown, where R, R, and R are alkyl groups. ne or more of these groups is an aryl group in s. R R R R amine R Secondary
Amines. Amines are organic compounds containing a nitrogen functionality. primary secondary tertiary quaternary
Amines Amines are organic compounds containing a nitrogen functionality Depending upon the number of alkyl, or aryl, groups attached to nitrogen determines its classification, or order 2 primary secondary
HW #4: 15.28, 15.30, 15.32, 15.40, 15.42, 15.44, 15.50, 15.54, 15.56, 15.58, 15.62, AMINES
Chemistry 131 Lecture 9: Amines - omenclature; Physical Properties; Heterocyclic Amines; Amine Reactivity, Amine Salts, Alkaloids Chapter 15 in McMurry, Ballantine, et. al. 7 th edition HW #4: 15.28, 15.30,
Question 13.1: Classify the following amines as primary, secondary or tertiary: (i) (ii) (iii) (C 2 H 5 ) 2 CHNH 2 (iv) (C 2 H 5 ) 2 NH Primary: (i) and (iii) Secondary: (iv) Tertiary: (ii) Question 13.2:
Chapter 22: Amines. Organic derivatives of ammonia, NH 3. Nitrogen atom have a lone pair of electrons, making the amine both basic and nucleophilic
hapter 22: Amines. rganic derivatives of ammonia, 3. itrogen atom have a lone pair of electrons, making the amine both basic and nucleophilic 22.1: Amines omenclature. (please read) sp 3 Amines are classified
AMINES. 3. From your knowledge of the effects involved, predict or explain experimental results. Important areas include:
AMINES A STUDENT SHOULD BE ABLE TO: 1. Name given the structure, and draw the structure given the name of amines and common nitrogen heterocycles (pyrrole and pyridine). Also, give the classification of
pentylamine or pentanamine cyclohexylamine or cyclohexanamine
omenclature - Amines: 1. Simple 1º Amines like simple ethers (no other functional groups), can simply name the alkyl group and end with the suffix -amine. Alternatively, you may remove the final e from
Chapter 22 Amines. Nomenclature Amines are classified according to the degree of substitution at nitrogen.
CH. 22 Chapter 22 Amines Amines are very important in biological chemistry. Most of the bases in biological acid-base reactions are amines. They are also very important nucleophiles in biochemical reactions.
Amines. Introduction Organic derivatives of ammonia. Many are biologically active.
Amines Introduction Organic derivatives of ammonia. Many are biologically active. 1 Biological Activity Neurotransmitters: dopamine Bioregulators: epinephrine Vitamins: niacin, B 6 Alkaloids: nicotine,
Ch15_PT MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question.
Ch15_PT MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. 1) What is the IUPAC name of the compound shown? 1) N-methylethylamine 2-propylamine 1-methylethylamine
Chapter 18 Amines and Neurotransmitters Based on Material Prepared by Andrea D. Leonard University of Louisiana at Lafayette
Chapter 18 Amines and Neurotransmitters Based on Material Prepared by Andrea D. Leonard University of Louisiana at Lafayette Copyright The McGraw-Hill Companies, Inc. Permission required for reproduction
AMINES. 3. Secondary When two hydrogen atoms are replaced by two alkyl or aryl groups.
AMINES Amine may be regarded as derivative of ammonia formed by replacement of one or more hydrogen atoms by corresponding number of alkyl or aryl group CLASSIFICATION 1. Ammonia 2. Primary amine 3. Secondary
Amines. Amines are bases usually the base involved in biochemical acid-base reactions.
Amines Amines Amines are derivatives of ammonia. Amines are bases usually the base involved in biochemical acid-base reactions. Vitamins comes from the term vital amines - not all vitamins are amines.
Q.1 Draw structures for all amines of molecular formula C 4 H 11 N. Classify them as primary, secondary or tertiary amines.
1 AMIES Structure ontain the 2 group. lassification primary (1 ) amines secondary (2 ) amines tertiary (3 ) amines quarternary (4 ) ammonium salts + 1 2 3 4 Aliphatic Aromatic methylamine, ethylamine,
Amines. Chapter 24 Organic Chemistry, 8th Edition. John McMurry
Amines Chapter 24 Organic Chemistry, 8th Edition John McMurry 1 Introduction Amines are stronger bases and better nucleophiles than other neutral organic compounds. 2 Nomenclature 1 Amines are named using
Amines. Many low molecular weight amines have foul odors.
1 Amines เอกสารประกอบการสอน รายว ชา 01403224 ดร.นงพงา จร สโสภณ Morphine 2 Interesting and Useful Amines Many low molecular weight amines have foul odors. Trimethylamine [(CH 3 ) 3 N], formed when enzymes
Chapter 15 Amines. Amines contain one or more organic groups bonded to nitrogen the compounds have these general formulas:
Chapter 15 Amines Amines have single bonds of Carbon bound to Nitrogen. Many of the molecules that carry chemical messages (such as neurotransmitters) are amines. They are present in many kinds of essential
Amines Chemical / Biological / Neurological Activity
Amines hemical / Biological / eurological Activity Measures of Basicity The basicity of amines may be measured by: 1) K b 2) pk b 3) K a of conjugate acid 4) pk a of conjugate acid Basicity onstant (K
1. LiAlH4 :.. :.. 2. H3O +
Ch 24 Amines Description of Amines - An amine is a compound with a nitrogen atom that has single bonds to carbon and hydrogen atoms. - An uncharged nitrogen atom normally has three bonds and a lone pair.
Downloaded from
Page 1 of 6 AMINES Amines are derivatives of ammonia (NH3), obtained by replacement of 1, 2 or all the 3 hydrogen atoms by alkyl and/or aryl groups. In nature amines are present in - proteins, vitamins,
Properties of Amines
Properties of Amines 1. Boiling Point and Water Solubility It is instructive to compare the boiling points and water solubility of amines with those of corresponding alcohols and ethers. The dominant factor
AMINES. Unit Write IUPAC names of the following :
Unit - 13 AMINES 1. Write IUPAC names of the following : 2. Giving an example of each, describe the following reactions : Hoffman bromamide reaction Gabriel phthanlimide synthesis Gatterman reaction Coupling
William H. Brown & Christopher S. Foote 22-1
William. Brown & Christopher S. Foote 22-1 Chapter 22 22-2 Structure & Classification Amines are classified as 1,, 2, 2, or, 3 3 amines amines in which 1, 2, or 3 hydrogens of N 3 are replaced by alkyl
*Basic info. P.3 *Naming convention P.4. *Class of amines
CONTENT *Basic info. P.3 *Naming convention P.4 *Physical property *Class of amines P57 P.5-7 P.8-18 BASIC INFO. Homologous series Primary alkamine Functional group Class of carbon compounds Amine (Aliphatic
Chapter AMINES
Chapter - 13 - AMINES Level one 1) Write IUPAC names of the following compounds and classify them into primary,secondary andteritary amines. a) (CH 3) 2CHNH 2 Ans:propan-2-amine(primary) b)ch 3(CH 2) 2NH
CHEMISTRY OF AMINES. There many organic nitrogen containing compounds, among which is amines. Organic nitrogen compounds are:
CHEMISTRY OF AMINES There many organic nitrogen containing compounds, among which is amines. Organic nitrogen compounds are: Amines RNH 2 Amide RCONH 2 Imine R R C=NR Nitrile RC N Generally amines are
Lecture 23. Amines. Chemistry 328N. April 12, 2016
Lecture 23 Amines April 12, 2016 Michael Reaction Michael reaction: conjugate addition of an enolate Arthur Michael anion to an, -unsaturated carbonyl compound!! Following are two examples in the first,
Chem 261 Dec 6, 2017
209 Chem 261 Dec 6, 2017 REVIEW: Example: K!! + 3 C + 3 C K tert-butoxide (an alkoxide) methanol tert-butanol pka = 16 pka = 19 methoxide stronger base stronger acid (lower pka, more acidic) weaker acid
R N R N R N. primary secondary tertiary
Chapter 19 Amines omenclature o assification of amines Amines are classified as 1, 2, or 3 based on how many R groups are attached to the nitrogen R R R R R R primary secondary tertiary When there are
ORGANIC - EGE 5E CH. 2 - COVALENT BONDING AND CHEMICAL REACTIVITY
!! www.clutchprep.com CONCEPT: HYBRID ORBITAL THEORY The Aufbau Principle states that electrons fill orbitals in order of increasing energy. If carbon has only two unfilled orbitals, why does it like to
Naming Organic Halides. Properties of Organic Halides
Organic Compounds Organic Halides A hydrocarbon in which one or more hydrogen atoms have been replaced by halogen atoms Freons (chlorofluorocarbons) in refrigeration and air conditioning Teflon (polytetrafluoroethane)
Chapter 21. Organic Chemistry 4 th Edition Paula Yurkanis Bruice. More About Amines. Heterocyclic Compounds
Organic Chemistry 4 th Edition Paula Yurkanis Bruice Chapter 21 More About Amines. Heterocyclic Compounds Irene Lee Case Western Reserve University Cleveland, OH 2004, Prentice Hall Amines An amine is
MODULE I (INORGANIC CHEMISTRY) 1. Coordination Chemistry: 10 Hrs. IUPAC Nomenclature of Co-ordination Compounds :
GOVERNMENT COLLEGE (AUTONOMOUS), RAJAMAHENDRAVARAM DEPARTMENT OF CHEMISTRY New CBCS Syllabus for B.Sc. III Year Effective from 2018 2019 onwards Paper V Semester V Syllabus Applied Inorganic Chemistry
An Introduction to Heterocyclic Chemistry
An Introduction to eterocyclic hemistry Reference: A Textbook of rganic hemistry, Tewari and Vishnoi This is only the introduction part of the unit on heterocyclic chemistry. Please refer textbook for
Electronegativity Scale F > O > Cl, N > Br > C, H
Organic Chem Chapter 12 Alkanes Organic chemistry is the study of carbon compounds. Carbon has several properties that are worth discussing: Tetravalent Always forms 4 bonds Can form multiple bonds (double
Ethers & Epoxides. Chapter 5. Dr. Seham ALTERARY. Chem 340-2nd semester
Ethers & Epoxides Chapter 5 Dr. Seham ALTERARY Chapter s out line Ethers Definition; General formula; Classification and Types Nomenclature - Common Names. - IUPAC Naming. Physical Properties General methods
Dr. Munther Abdujaleel M.A. Assist. Prof. Org. Chem.
Dr. Munther Abdujaleel M.A. Assist. Prof. Org. Chem. Amines An amine, derivatives of ammonia NH 3 has the general formula RNH 2, R 2 NH, or R 3 N, where R is any alkyl or aryl group. For example: Adernalin
19.4 Physical Properties Key: hydrogen bond strength depends on acidity of the hydrogen and basicity of the N or O
Chem 360 Jasperse Ch. 19 Notes. Amines 12 19.4 ysical Properties Key: hydrogen bond strength depends on acidity of the hydrogen and basicity of the N or 1. Water Solubility: All amines hydrogen-bond water
٢
Amines ١ ٢ ٣ ٤ ٥ ٦ ٧ ٨ ٩ ١٠ ١١ Physical Properties of Amines - Amines are moderately polar. For this reason the low formula weight amines are readily soluble in water due to the formation of hydrogen bonds
Amines (McM chapt 24)
Amines (McM chapt 24) (: alkyl, aryl) - 2 Primary amine ' Secondary amine '' ' Tertiary amine ' ''' '' Quartenary ammonium salts Basic compounds ' '' - ' '' + pka Alkylamines: ca 9-11 Arylamines: ca 4-5
OCR Chemistry A H432. Amines are described as primary, secondary or tertiary depending on how many carbons are bonded to the N atom.
OCR Chemistry A 432 About amines: can be considered as derivatives of ammonia, with one or more of the atoms replaced by alkyl groups. They are noted for their unpleasant, often fishy odours. We classify
Nomenclature of Organic Compounds Identification of Functional Groups
Hydrocarbons Nomenclature of Organic ompounds Identification of Functional Groups Alkanes - also known as saturated hydrocarbons or the paraffin series because all bond sites between carbon atoms and between
Carbon-heteroatom single bonds basic C N C X. X= F, Cl, Br, I Alkyl Halide C O. epoxide Chapter 14 H. alcohols acidic H C S C. thiols.
hapter 13: Alcohols and Phenols 13.1 Structure and Properties of Alcohols Alkanes arbon - arbon Multiple Bonds arbon-heteroatom single bonds basic Alkenes X X= F, l,, I Alkyl alide amines hapter 23 nitro
Amines and Heterocycles. McMurry: Chapter 24
Amines and Heterocycles McMurry: Chapter 24 Introduction to Amines and Heterocycles Amines and heterocycles (cyclic amines) are ammonia derivatives, many of whichare found widely in livingorganisms: 2
Dr. Mohamed El-Newehy
By Dr. Mohamed El-Newehy Chemistry Department, College of Science, King Saud University http://fac.ksu.edu.sa/melnewehy Carboxylic acids and Their Derivatives 1 Structure of Carboxylic Acids -The functional
CHE1502. Tutorial letter 203/1/2016. General Chemistry 1B. Semester 1. Department of Chemistry
E1502/203/1/2016 Tutorial letter 203/1/2016 General hemistry 1B E1502 Semester 1 Department of hemistry This tutorial letter contains the answers to the questions in assignment 3. FIRST SEMESTER: KEY T
2016 Pearson Education, Inc. Isolated and Conjugated Dienes
2016 Pearson Education, Inc. Isolated and Conjugated Dienes 2016 Pearson Education, Inc. Reactions of Isolated Dienes 2016 Pearson Education, Inc. The Mechanism Double Bonds can have Different Reactivities
Chemistry Questions ans Answers BASED ON HIGH ORDER THINKING SKILL (HOTS) UNIT- 13 ORGANIC COMPOUNDS CONTAINING NITROGEN
Chemistry Questions ans Answers BASED N HIGH RDER THINKING SKILL (HTS) UNIT- 13 RGANIC CMPUNDS CNTAINING NITRGEN 1 MARK QUESTINS Q. 1. Why the presence of a base is essential in the ammonolysis of alkyl
Reducing Agents. Linda M. Sweeting 1998
Reducing Agents Linda M. Sweeting 1998 Reduction is defined in chemistry as loss of oxygen, gain of hydrogen or gain of electrons; the gain of electrons enables you to calculate an oxidation state. Hydride
Class XII: Chemistry Chapter 13: Amines Top concepts
Class XII: Chemistry Chapter 13: Amines Top concepts 1. Amines are regarded as derivatives of ammonia in which one, two or all three hydrogen atoms are replaced by alkyl or aryl group 2. Classification
Chapter 16 Aromatic Compounds. Discovery of Benzene
Chapter 16 Aromatic Compounds Discovery of Benzene Isolated in 1825 by Michael Faraday who determined C: ratio to be 1:1. Synthesized in 1834 by Eilhard Mitscherlich who determined molecular formula to
1. methyl 2. methylene 3. methine 4. primary 5. secondary 6. tertiary 7. quarternary 8. isopropyl
hem 201 Sample Midterm Beauchamp Exams are designed so that no one question will make or break you. The best strategy is to work steadily, starting with those problems you understand best. Make sure you
Chapter 6: Organic Halogen Compounds; Substitution and Elimination Reactions
Chapter 6: Organic Halogen Compounds; Substitution and Elimination Reactions Halogen compounds are important for several reasons. Simple alkyl and aryl halides, especially chlorides and bromides, are versatile
Chapter 8. Acidity, Basicity and pk a
Chapter 8 Acidity, Basicity and pk a p182 In this reaction water is acting as a base, according to our definition above, by accepting a proton from HCl which in turn is acting as an acid by donating a
Ammonia Primary Secondary Tertiary Quarternary Ammonium Ion
1 Chapter 19: Amines I. Introduction: Classification: NH 3 RNH 2 R 2 NH R 3 N R 4 N + Ammonia Primary Secondary Tertiary Quarternary Ammonium Ion Amines are a very common functional group in organic chemistry,
Chemistry 506: Allied Health Chemistry 2. Chapter 15: Amines and Amides. Functional Groups with Single Bonds to Nitrogen
Chemistry 506 Dr. Hunter s Class Chapter 15. Chemistry 506: Allied Health Chemistry 2 1 Chapter 15: Amines and Amides Functional Groups with Single Bonds to Nitrogen Introduction to General, Organic &
Unless otherwise stated, all images in this file have been reproduced from:
Unless otherwise stated, all images in this file have been reproduced from: Blackman, Bottle, Schmid, Mocerino and Wille, hemistry, 2007 (John Wiley) ISBN: 9 78047081 0866 1 hemistry 1B EM1002 Lecture
Page 1 of 9. Sessional Examination (November 2017) Max Marks: 20 Date: Time: One Hour. Model Answers
Page 1 of 9 Sessional Examination (November 2017) Class: B. Pharm-II yr (III sem) Subject: Pharma Org. Chem-II Max Marks: 20 Date: 14.11.2017 Time: One Hour Model Answers Q. 1. Solve the following (ANY
What happens when methanamine reacts with FeCl 3? Methylamine in water reacts with FeCl 3 to givebrown precipitate of hydrated ferric oxide:
What happens when methanamine reacts with FeCl 3? Methylamine in water reacts with FeCl 3 to givebrown precipitate of hydrated ferric oxide: Due to the electron donating inductive or +I effect of CH 3
Ammonia and Amines. Four sp 3 hybridized orbitals. Three used for bonding and one for the lone pair of electrons. secondary 2. Et Me.
Ammonia and Amines threefold axis of rotation 111 107 Four sp 3 hybridized orbitals. Three used for bonding and one for the lone pair of electrons. trigonal pyramidal primary 1 secondary 2 tertiary 3 quaternary
Chemistry 110. Bettelheim, Brown, Campbell & Farrell. Ninth Edition
Chemistry 110 Bettelheim, Brown, Campbell & Farrell Ninth Edition Introduction to General, rganic and Biochemistry Chapter 14 Alcohols, Ethers and Thiols Alcohols have a ydroxyl Group, -, bonded to tetrahedral
6.10 Amines. Naming. N Goalby chemrevise.org 1 CH2 CH2
6.10 Amines aming Amines These end in amine. There is, however, rather confusingly two ways of using this suffix. The exam board tend to use the common version where the name stem ends in -yl propylamine.
Organic Chemistry, 7 L. G. Wade, Jr. 2010, Prentice Hall
Organic Chemistry, 7 th Edition L. G. Wade, Jr. Chapter 16 Aromatic Compounds 2010, Prentice Hall Discovery of Benzene Isolated in 1825 by Michael Faraday who determined C:H ratio to be 1:1. Synthesized
MCAT Organic Chemistry Problem Drill 10: Aldehydes and Ketones
MCAT rganic Chemistry Problem Drill 10: Aldehydes and Ketones Question No. 1 of 10 Question 1. Which of the following is not a physical property of aldehydes and ketones? Question #01 (A) Hydrogen bonding
Chem 1075 Chapter 19 Organic Chemistry Lecture Outline
Chem 1075 Chapter 19 Organic Chemistry Lecture Outline Slide 2 Introduction Organic chemistry is the study of and its compounds. The major sources of carbon are the fossil fuels: petroleum, natural gas,
Chem 263 Dec 6, The following reaction occurs in bad wine (wine containing acetic acid). O + O OH 2 O H O + 2 O Na + O
hem 263 Dec 6, 2016 onversion of Acids to Esters The following reaction occurs in bad wine (wine containing acetic acid). 3 + + 3 + Acetic acid Ethanol Ethyl Acetate Mechanism: + 2 + 3 3 + 3 Would an ester
ORGANIC - BRUICE 8E CH.3 - AN INTRODUCTION TO ORGANIC COMPOUNDS
!! www.clutchprep.com CONCEPT: INDEX OF HYDROGEN DEFICIENCY (STRUCTURAL) A saturated molecule is any molecule that has the maximum number of hydrogens possible for its chemical structure. The rule that
10. Alkyl Halides. What Is an Alkyl Halide. An organic compound containing at least one carbonhalogen
10. Alkyl Halides What Is an Alkyl Halide An organic compound containing at least one carbonhalogen bond (C-X) X (F, Cl, Br, I) replaces H Can contain many C-X bonds Properties and some uses Fire-resistant
Aromatic Compounds I
2302272 Org Chem II Part I Lecture 1 Aromatic Compounds I Instructor: Dr. Tanatorn Khotavivattana E-mail: tanatorn.k@chula.ac.th Recommended Textbook: Chapter 16 in Organic Chemistry, 8 th Edition, L.
Amines. Types of Amines. chemrevise.org. N Goalby Chemrevise.org. primary amine (one C attached to N) H. Secondary amine (two C s.
Amines Goalby hemrevise.org Types of Amines primary amine (one attached to ) Secondary amine (two s attached to ) 3 2 2 3 name : diethylamine It is also possible to have aromatic amines 2 phenylamine name:
13. AMINES. 4-Bromobenzenamine or 4-Bromoaniline. p-bromoaniline. AMINES-Anil-Hsslive Page 1
13. AMINES Amines are the derivatives of ammonia. Like ammonia, the nitrogen atom in amines is also sp 3 hybridised with an unpaired electron in one of the sp 3 hybridised orbitals. So the shape of amines
Molecular Geometry: VSEPR model stand for valence-shell electron-pair repulsion and predicts the 3D shape of molecules that are formed in bonding.
Molecular Geometry: VSEPR model stand for valence-shell electron-pair repulsion and predicts the 3D shape of molecules that are formed in bonding. Sigma and Pi Bonds: All single bonds are sigma(σ), that
Chapter 22. Organic and Biological Molecules
Chapter 22 Organic and Biological Molecules The Bonding of Carbon Organic chemistry is the chemistry of compounds containing carbon. Because carbon can form single, double, and triple bonds, the following
Aromatic Hydrocarbons
Aromatic Hydrocarbons Aromatic hydrocarbons contain six-membered rings of carbon atoms with alternating single and double carbon-carbon bonds. The ring is sometimes shown with a circle in the center instead
Alkanes and Cycloalkanes
Alkanes and Cycloalkanes Families of Organic Compounds Organic compounds can be grouped into families by their common structural features We shall survey the nature of the compounds in a tour of the families
Aromatic Compounds II
2302272 Org Chem II Part I Lecture 2 Aromatic Compounds II Instructor: Dr. Tanatorn Khotavivattana E-mail: tanatorn.k@chula.ac.th Recommended Textbook: Chapter 17 in Organic Chemistry, 8 th Edition, L.
Chem 225 Notes Page 128. Chapter 23: Amines
Chem 225 Notes Page 128 Chapter 23: Amines I. Introduction A. Classification of Amines Amines are classified by the number of carbon groups attached to the nitrogen: ammonia primary (1 o ) secondary (2