Electronic Supplementary Information

Size: px
Start display at page:

Download "Electronic Supplementary Information"

Transcription

1 Electronic Supplementary Information A Sensitive Phosphorescent Thiol Chemosensor Based on an Iridium(III) Complex with α,β-unsaturated Ketone Functionalized 2,2 -Bipyridyl Ligand Na Zhao, a Yu-Hui Wu, a Lin-Xi Shi, a Qi-Pu Lin, a and Zhong-Ning Chen *,a,b State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian , China, and State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai , China S1

2 Table S1. Partial Molecular Orbital Compositions (%) of 1 in DMF media under the TD-DFT Calculations. Orbital Energy (ev) MO contribution (%) Ir L ligand ppy 2,2 -bpy -C(O)C 6 H 4 N(C 2 H 5 ) 2 LUMO LUMO LUMO LUMO HOMO HOMO HOMO Table S2. TD-DFT Calculated Singlet Absorption Data and the Measured Absorption Data for 1 in DMF Media. Transition CI Coef. E, nm (ev) O.S. Assignment Measured value (nm) S1 HOMO 1 LUMO (2.42) MLCT / 1 LLCT S2 HOMO LUMO (2.61) ILCT 430,460 S6 HOMO LUMO (3.27) ILCT S31 HOMO LUMO (4.31) ILCT / 1 LLCT 298, 270 HOMO 6 LUMO MLCT/ 1 LLCT HOMO LUMO ILCT/ 1 LLCT S2

3 Table S3. Partial Molecular Orbital Compositions(%) of 1-Cys in DMF solution under the TD-DFT Calculations. Orbital Energy (ev) MO contribution (%) Ir L ligand ppy 2,2 -bpy -C(O)C 6 H 4 N(C 2 H 5 ) 2 LUMO LUMO LUMO HOMO HOMO HOMO Table S4. TD-DFT Calculated Singlet Absorption Data in DMF Media and the Measured Absorption Data for the adduct 1-Cys in DMF media. Transition CI Coef. E, nm (ev) O.S. Assignment Measured value (nm) S1 HOMO 1 LUMO (2.68) MLCT / 1 LLCT 416 S2 HOMO LUMO (3.08) ILCT S6 HOMO 2 LUMO (3.44) LLCT/ 1 MLCT 348 HOMO 1 LUMO MLCT / 1 ILCT S18 HOMO LUMO (4.02) ILCT 312,280 S3

4 Table S5 DFT Optimized Coordinates for 1-Cys Center Atomic Coordinates (Angstroms) Number Number X Y Z S4

5 S5

6 S6

7 S7

8 1.2 Absorbance L ligand Wavelength (nm) Fig. S1. UV vis absorption spectra of complex 1 and L ligand (20 μm) in DMF HEPES buffer solution (50 mm, ph 7.2, 4:1, v/v). 1.0 Absorbance Wavelength (nm) Fig. S2. Changes of UV vis absorption spectra for complex 1 (20 μm) in DMF HEPES buffer (50 mm, ph 7.2, 4:1, v/v) upon titration with Hcy (0 80 equiv). The equilibration time is about 300 min. S8

9 0.6 Absorbance Wavelength (nm) Fig. S3. Changes of UV vis absorption spectra for the ligand L (20 μm) in DMF HEPES buffer (50 mm, ph 7.2, 4:1, v/v) upon titration with Cys (0 60 equiv). 600 Emission Intensity Wavelength (nm) Fig. S4. Changes of emission spectra for complex 1 (20 μm) in DMF HEPES buffer (50 mm, ph 7.2, 4:1, v/v) upon titration with Hys (0 80 equiv). The equilibration time is about 300 min. S9

10 Emission Intensity Y = * X R = Concentration(10 5 M) Fig. S5. Plot of Hcy concentration dependence of the emission intensity at 587 nm. Emission Intensity Cys Hcy GSH t (min) Fig. S6. Time course of the emission intensity at 587 nm for complex 1 (20 μm) upon addition of 80 equiv of Cys, Hcy, or GSH in 300 min (25 o C). S10

11 Fig. S7. Positive ion ESI spectra of 1 before (a) and after (b) addition of 80 equiv Cys. H a O N HOOC NH 2 S O N H a' Cys H d N N N N H a H a H d Fig. S8. 1 H NMR spectra of free L before (a) and after (b) addition of 5 equiv Cys in d 6 -DMSO. S11

12 Fig. S9. The 1 H 1 H COSY spectrum of complex 1 in d 6 -DMSO. Fig. S10. The 1 H 1 H COSY spectrum of complex 2 in d 6 -DMSO. S12

13 Fig. S11. The 1 H 1 H COSY spectrum of complex 1 and 5 equiv in d 6 -DMSO H 2 O. 800 Emission Intensity Gly Ala Thr Ser Val Leu Ile Trp Phe Met Pro Gln Lys Asn Asp Glu His Arg Tyr Fig. S12. Emission response of complex 1 (20 μm) in the presence of both Cys and another competing amino acid (both 80 equiv) in DMF HEPES buffer solution (50 mm, ph 7.2, 4:1, v/v). The excitation wavelength was 358 nm. S13

14 1000 Emission Intensity Cys(80 equiv) ph Fig. S13. The emission intensities at 587 nm for 1 (20 μm) in the absence ( ) or presence ( ) of Cys (80 equiv) at various ph values. The excitation wavelength is 358 nm. Absorbance CH 3 CN CH 2 Cl 2 DMF Wavelength (nm) Fig. S14. UV vis absorption spectra of complex 1 (20 μm) in CH 3 CN (black), CH 2 Cl 2 (red) and DMF (blue) solutions. S14

15 Fig. S15. Optimized structures of 1 (top) and 1-Cys (bottom) in the ground state by DFT method. S15

16 Absorbance Oscillator Strength Wavelength (nm) Fig. S16. Calculated (red bars) absorption and experimentally measured (blue line) UV vis spectrum (20 μm) of 1 in DMF solution at ambient temperature. Absorbance Oscillator Strength Wavelength (nm) Fig. S17. Calculated (red bars) absorptions in DMF media and experimentally measured (blue line) UV vis spectrum (20 μm) of the adduct 1-Cys in DMF HEPES buffer solution (50 mm, ph 7.2, 4:1, v/v). S16

17 LUMO+6 LUMO+5 LUMO+1 LUMO HOMO HOMO 1 HOMO 6 Fig. S18. Electron-density diagrams of the frontier molecular orbitals involved in absorption of 1 in DMF media. S17

18 LUMO+4 LUMO+3 LUMO HOMO HOMO 1 HOMO 2 Fig. S19. Electron-density diagrams of the frontier molecular orbitals involved in absorption of 1-Cys in DMF media. S18

Studies Leading to the Development of a Highly Selective. Colorimetric and Fluorescent Chemosensor for Lysine

Studies Leading to the Development of a Highly Selective. Colorimetric and Fluorescent Chemosensor for Lysine Supporting Information for Studies Leading to the Development of a Highly Selective Colorimetric and Fluorescent Chemosensor for Lysine Ying Zhou, a Jiyeon Won, c Jin Yong Lee, c * and Juyoung Yoon a,

More information

Proteins: Characteristics and Properties of Amino Acids

Proteins: Characteristics and Properties of Amino Acids SBI4U:Biochemistry Macromolecules Eachaminoacidhasatleastoneamineandoneacidfunctionalgroupasthe nameimplies.thedifferentpropertiesresultfromvariationsinthestructuresof differentrgroups.thergroupisoftenreferredtoastheaminoacidsidechain.

More information

Amino Acid Side Chain Induced Selectivity in the Hydrolysis of Peptides Catalyzed by a Zr(IV)-Substituted Wells-Dawson Type Polyoxometalate

Amino Acid Side Chain Induced Selectivity in the Hydrolysis of Peptides Catalyzed by a Zr(IV)-Substituted Wells-Dawson Type Polyoxometalate Amino Acid Side Chain Induced Selectivity in the Hydrolysis of Peptides Catalyzed by a Zr(IV)-Substituted Wells-Dawson Type Polyoxometalate Stef Vanhaecht, Gregory Absillis, Tatjana N. Parac-Vogt* Department

More information

Other Methods for Generating Ions 1. MALDI matrix assisted laser desorption ionization MS 2. Spray ionization techniques 3. Fast atom bombardment 4.

Other Methods for Generating Ions 1. MALDI matrix assisted laser desorption ionization MS 2. Spray ionization techniques 3. Fast atom bombardment 4. Other Methods for Generating Ions 1. MALDI matrix assisted laser desorption ionization MS 2. Spray ionization techniques 3. Fast atom bombardment 4. Field Desorption 5. MS MS techniques Matrix assisted

More information

A novel coumarin based molecular switch for dual sensing of

A novel coumarin based molecular switch for dual sensing of Electronic Supplementary Material (ESI) for RSC Advances. This journal is The Royal Society of Chemistry 2014 Supporting Information A novel coumarin based molecular switch for dual sensing of Zn(II) and

More information

A Plausible Model Correlates Prebiotic Peptide Synthesis with. Primordial Genetic Code

A Plausible Model Correlates Prebiotic Peptide Synthesis with. Primordial Genetic Code Electronic Supplementary Material (ESI) for ChemComm. This journal is The Royal Society of Chemistry 2018 A Plausible Model Correlates Prebiotic Peptide Synthesis with Primordial Genetic Code Jianxi Ying,

More information

Supporting information

Supporting information Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2015 Supporting information Influence

More information

Molecular Selective Binding of Basic Amino Acids by a Water-soluble Pillar[5]arene

Molecular Selective Binding of Basic Amino Acids by a Water-soluble Pillar[5]arene Electronic supplementary information Molecular Selective Binding of Basic Amino Acids y a Water-solule Pillar[5]arene Chunju Li,* a, Junwei Ma, a Liu Zhao, a Yanyan Zhang, c Yihua Yu, c Xiaoyan Shu, a

More information

A ratiometric fluorescent probe for specific detection of cysteine over. homocysteine and glutathione based on the drastic distinction in the

A ratiometric fluorescent probe for specific detection of cysteine over. homocysteine and glutathione based on the drastic distinction in the Supporting Information for A ratiometric fluorescent probe for specific detection of cysteine over homocysteine and glutathione based on the drastic distinction in the kinetic profiles Lin Yuan, Weiying

More information

NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease

NMR study of complexes between low molecular mass inhibitors and the West Nile virus NS2B-NS3 protease University of Wollongong Research Online Faculty of Science - Papers (Archive) Faculty of Science, Medicine and Health 2009 NMR study of complexes between low molecular mass inhibitors and the West Nile

More information

Supporting Information. Copyright Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2008

Supporting Information. Copyright Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, 2008 Supporting Information Copyright Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, 2008 Highly Sensitive and Fast Responsive Fluorescence Turn-on Chemodosimeter for Cu 2+ and its Application in Live Cell

More information

Ramachandran Plot. 4ysz Phi (degrees) Plot statistics

Ramachandran Plot. 4ysz Phi (degrees) Plot statistics B Ramachandran Plot ~b b 135 b ~b ~l l Psi (degrees) 5-5 a A ~a L - -135 SER HIS (F) 59 (G) SER (B) ~b b LYS ASP ASP 315 13 13 (A) (F) (B) LYS ALA ALA 315 173 (E) 173 (E)(A) ~p p ~b - -135 - -5 5 135 (degrees)

More information

Unraveling the degradation of artificial amide bonds in Nylon oligomer hydrolase: From induced-fit to acylation processes

Unraveling the degradation of artificial amide bonds in Nylon oligomer hydrolase: From induced-fit to acylation processes Electronic Supplementary Material (ESI) for Physical Chemistry Chemical Physics. This journal is the Owner Societies 2015 Supporting Information for Unraveling the degradation of artificial amide bonds

More information

Oxygen Binding in Hemocyanin

Oxygen Binding in Hemocyanin Supporting Information for Quantum Mechanics/Molecular Mechanics Study of Oxygen Binding in Hemocyanin Toru Saito and Walter Thiel* Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470

More information

What makes a good graphene-binding peptide? Adsorption of amino acids and peptides at aqueous graphene interfaces: Electronic Supplementary

What makes a good graphene-binding peptide? Adsorption of amino acids and peptides at aqueous graphene interfaces: Electronic Supplementary Electronic Supplementary Material (ESI) for Journal of Materials Chemistry B. This journal is The Royal Society of Chemistry 21 What makes a good graphene-binding peptide? Adsorption of amino acids and

More information

Electronic Supplementary Information

Electronic Supplementary Information Electronic Supplementary Information 1. Reagents All the L-amino acids and L-glutathione (reduced form) were purchased from Sangon Biotch. o. (Shanghai, hina); Methyl orange, potassium tetrachloropalladate(ii),

More information

Arylazoimidazole complexes of lead(ii)-halide and their photochromism

Arylazoimidazole complexes of lead(ii)-halide and their photochromism 1 Electronic Supplementary Data Arylazoimidazole complexes of lead(ii)-halide and their photochromism Debashis Mallick a, Bharati Chowdhury b, Chandana Sen b, Kamal Krishna Sarkar c, Srikanta Jana b, Sudipa

More information

Peptide Syntheses. Illustrative Protection: BOC/ t Bu. A. Introduction. do not acid

Peptide Syntheses. Illustrative Protection: BOC/ t Bu. A. Introduction. do not acid Kevin Burgess, May 3, 2017 1 Peptide yntheses from chapter(s) in the recommended text A. Introduction do not acid -Met-e- -Met-Met- -e-e- -e-met- dipeptide dipeptide dipeptide dipeptide diketopiperazine

More information

Supplementary information

Supplementary information Electronic Supplementary Material (ESI) for Dalton Transactions. This journal is The Royal Society of Chemistry 2018 Spectroscopy, electrochemistry and antiproliferative properties of Au(III), Pt(II) and

More information

Supplementary Information

Supplementary Information Electronic Supplementary Material (ESI) for Dalton Transactions. This journal is The Royal Society of Chemistry 2015 Supplementary Information Comparative study of Ir(III) complexes with pyrazino[2,3-

More information

Chapter 4: Amino Acids

Chapter 4: Amino Acids Chapter 4: Amino Acids All peptides and polypeptides are polymers of alpha-amino acids. lipid polysaccharide enzyme 1940s 1980s. Lipids membrane 1960s. Polysaccharide Are energy metabolites and many of

More information

A long-lived iridium(iii) chemosensor for the real-time

A long-lived iridium(iii) chemosensor for the real-time Electronic Supplementary Material (ESI) for Journal of Materials Chemistry B. This journal is The Royal Society of Chemistry 2017 Supporting Information A long-lived iridium(iii) chemosensor for the real-time

More information

Stereocontrolled Self-Assembly and Photochromic Transformation of

Stereocontrolled Self-Assembly and Photochromic Transformation of Electronic Supplementary Material (ESI) for Dalton Transactions. This journal is The Royal Society of Chemistry 2018 Supporting Information for Stereocontrolled Self-Assembly and Photochromic Transformation

More information

Supplementary Material (ESI) for Dalton Transactions This journal is The Royal Society of Chemistry 2011

Supplementary Material (ESI) for Dalton Transactions This journal is The Royal Society of Chemistry 2011 upplementary Material (EI) for Dalton Transactions This journal is The Royal ociety of Chemistry 211 Electronic upplementary Information for: Accessing the long-lived emissive 3 IL triplet excited states

More information

A Novel Fluorescent Chemosensor Based on Tetra-peptide for Measuring Zinc Ions in Aqueous Solutions and Live Cells

A Novel Fluorescent Chemosensor Based on Tetra-peptide for Measuring Zinc Ions in Aqueous Solutions and Live Cells Electronic Supplementary Material (ESI) for Journal of Materials Chemistry B. Electronic Supplementary Material (ESI) for Journal of Materials Chemistry B. Supporting Information A Novel Fluorescent Chemosensor

More information

CHMI 2227 EL. Biochemistry I. Test January Prof : Eric R. Gauthier, Ph.D.

CHMI 2227 EL. Biochemistry I. Test January Prof : Eric R. Gauthier, Ph.D. CHMI 2227 EL Biochemistry I Test 1 26 January 2007 Prof : Eric R. Gauthier, Ph.D. Guidelines: 1) Duration: 55 min 2) 14 questions, on 7 pages. For 70 marks (5 marks per question). Worth 15 % of the final

More information

Clustering and Model Integration under the Wasserstein Metric. Jia Li Department of Statistics Penn State University

Clustering and Model Integration under the Wasserstein Metric. Jia Li Department of Statistics Penn State University Clustering and Model Integration under the Wasserstein Metric Jia Li Department of Statistics Penn State University Clustering Data represented by vectors or pairwise distances. Methods Top- down approaches

More information

Sequential resonance assignments in (small) proteins: homonuclear method 2º structure determination

Sequential resonance assignments in (small) proteins: homonuclear method 2º structure determination Lecture 9 M230 Feigon Sequential resonance assignments in (small) proteins: homonuclear method 2º structure determination Reading resources v Roberts NMR of Macromolecules, Chap 4 by Christina Redfield

More information

Supporting Information

Supporting Information Selective Hg 2+ sensing behaviors of rhodamine derivatives with extended conjugation based on two successive ring-opening processes Chunyan Wang a,b and Keith Man-Chung Wong a,b * a Department of Chemistry,

More information

Desorption/Ionization Efficiency of Common Amino Acids in. Surface-assisted Laser Desorption/ionization Mass Spectrometry

Desorption/Ionization Efficiency of Common Amino Acids in. Surface-assisted Laser Desorption/ionization Mass Spectrometry SUPPORTING INFORMATION Desorption/Ionization Efficiency of Common Amino Acids in Surface-assisted Laser Desorption/ionization Mass Spectrometry (SALDI-MS) with Nanostructured Platinum Syuhei Nitta, Hideya

More information

Exam III. Please read through each question carefully, and make sure you provide all of the requested information.

Exam III. Please read through each question carefully, and make sure you provide all of the requested information. 09-107 onors Chemistry ame Exam III Please read through each question carefully, and make sure you provide all of the requested information. 1. A series of octahedral metal compounds are made from 1 mol

More information

A. Two of the common amino acids are analyzed. Amino acid X and amino acid Y both have an isoionic point in the range of

A. Two of the common amino acids are analyzed. Amino acid X and amino acid Y both have an isoionic point in the range of Questions with Answers- Amino Acids & Peptides A. Two of the common amino acids are analyzed. Amino acid X and amino acid Y both have an isoionic point in the range of 5.0-6.5 (Questions 1-4) 1. Which

More information

Red-Emitting Ruthenium(II) and Iridium(III) Complexes as. Phosphorescent Probes for Methylglyoxal in vitro and in vivo

Red-Emitting Ruthenium(II) and Iridium(III) Complexes as. Phosphorescent Probes for Methylglyoxal in vitro and in vivo Supporting information for: Red-Emitting Ruthenium(II) and Iridium(III) Complexes as Phosphorescent Probes for Methylglyoxal in vitro and in vivo Wenzhu Zhang, *, Feiyue Zhang, Yong-Lei Wang, Bo Song,

More information

C H E M I S T R Y N A T I O N A L Q U A L I F Y I N G E X A M I N A T I O N SOLUTIONS GUIDE

C H E M I S T R Y N A T I O N A L Q U A L I F Y I N G E X A M I N A T I O N SOLUTIONS GUIDE C H E M I S T R Y 2 0 0 0 A T I A L Q U A L I F Y I G E X A M I A T I SLUTIS GUIDE Answers are a guide only and do not represent a preferred method of solving problems. Section A 1B, 2A, 3C, 4C, 5D, 6D,

More information

Electronic supplementary information. Strong CIE activity, multi-stimuli-responsive fluorescence and data

Electronic supplementary information. Strong CIE activity, multi-stimuli-responsive fluorescence and data Electronic Supplementary Material (ESI) for Journal of Materials Chemistry C. This journal is The Royal Society of Chemistry 2015 Electronic supplementary information Strong CIE activity, multi-stimuli-responsive

More information

Supplementary Information Intrinsic Localized Modes in Proteins

Supplementary Information Intrinsic Localized Modes in Proteins Supplementary Information Intrinsic Localized Modes in Proteins Adrien Nicolaï 1,, Patrice Delarue and Patrick Senet, 1 Department of Physics, Applied Physics and Astronomy, Rensselaer Polytechnic Institute,

More information

Protein Fragment Search Program ver Overview: Contents:

Protein Fragment Search Program ver Overview: Contents: Protein Fragment Search Program ver 1.1.1 Developed by: BioPhysics Laboratory, Faculty of Life and Environmental Science, Shimane University 1060 Nishikawatsu-cho, Matsue-shi, Shimane, 690-8504, Japan

More information

Amino Acids and Proteins at ZnO-water Interfaces in Molecular Dynamics Simulations: Electronic Supplementary Information

Amino Acids and Proteins at ZnO-water Interfaces in Molecular Dynamics Simulations: Electronic Supplementary Information Amino Acids and Proteins at ZnO-water Interfaces in Molecular Dynamics Simulations: Electronic Supplementary Information Grzegorz Nawrocki and Marek Cieplak Institute of Physics, Polish Academy of Sciences,

More information

The first Re I organometallic complex with an organoimidopolyoxometalate

The first Re I organometallic complex with an organoimidopolyoxometalate Electronic Supplementary Material (ESI) for Dalton Transactions. This journal is The Royal Society of Chemistry 2017 Electronic Supplementary Information The first Re I organometallic complex with an organoimidopolyoxometalate

More information

Supporting information

Supporting information Supporting information Sensitizing Tb(III) and Eu(III) Emission with Triarylboron Functionalized 1,3-diketonato Ligands Larissa F. Smith, Barry A. Blight, Hee-Jun Park, and Suning Wang* Department of Chemistry,

More information

Colorimetric and fluorescent probe for detection of nanomolar lysine in aqueous medium

Colorimetric and fluorescent probe for detection of nanomolar lysine in aqueous medium Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is The Royal Society of Chemistry 2016 Colorimetric and fluorescent probe for detection of nanomolar lysine in

More information

Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets

Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets Supporting information Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets Wan-Na Chen, Christoph Nitsche, Kala Bharath Pilla, Bim Graham, Thomas

More information

Supporting Information For:

Supporting Information For: Supporting Information For: Highly Fluorinated Ir(III)- 2,2 :6,2 -Terpyridine -Phenylpyridine-X Complexes via Selective C-F Activation: Robust Photocatalysts for Solar Fuel Generation and Photoredox Catalysis

More information

Exam I Answer Key: Summer 2006, Semester C

Exam I Answer Key: Summer 2006, Semester C 1. Which of the following tripeptides would migrate most rapidly towards the negative electrode if electrophoresis is carried out at ph 3.0? a. gly-gly-gly b. glu-glu-asp c. lys-glu-lys d. val-asn-lys

More information

Supplementary Information. Broad Spectrum Anti-Influenza Agents by Inhibiting Self- Association of Matrix Protein 1

Supplementary Information. Broad Spectrum Anti-Influenza Agents by Inhibiting Self- Association of Matrix Protein 1 Supplementary Information Broad Spectrum Anti-Influenza Agents by Inhibiting Self- Association of Matrix Protein 1 Philip D. Mosier 1, Meng-Jung Chiang 2, Zhengshi Lin 2, Yamei Gao 2, Bashayer Althufairi

More information

Self-Assembly of Single Amino acid-pyrene Conjugates with Unique Structure-Morphology Relationship

Self-Assembly of Single Amino acid-pyrene Conjugates with Unique Structure-Morphology Relationship Electronic Supplementary Material (ESI) for Soft Matter. This journal is The Royal Society of Chemistry 2017 Self-Assembly of Single Amino acid-pyrene Conjugates with Unique Structure-Morphology Relationship

More information

Rhodamine-based Chemosensor for Hg 2+ in Aqueous Solution with a Broad ph Range and Its Application in Live Cell Imaging

Rhodamine-based Chemosensor for Hg 2+ in Aqueous Solution with a Broad ph Range and Its Application in Live Cell Imaging Rhodamine-based Chemosensor for Hg + in Aqueous Solution with a Broad ph Range and Its Application in Live Cell Imaging Yun Zhao, Yue Sun, Xin Lv, Yunlong Liu, Maliang Chen, and Wei Guo* School of Chemistry

More information

Deciphering the Rules for Amino Acid Co- Assembly Based on Interlayer Distances

Deciphering the Rules for Amino Acid Co- Assembly Based on Interlayer Distances Supporting Information Deciphering the Rules for Amino Acid Co- Assembly Based on Interlayer Distances Santu Bera, Sudipta Mondal, Yiming Tang, Guy Jacoby, Elad Arad, ǁ Tom Guterman, Raz Jelinek, ǁ Roy

More information

Supporting Information for Rapid and Highly Sensitive Dual-Channel Detection of Cyanide by Bis-heteroleptic Ruthenium(II) Complexes

Supporting Information for Rapid and Highly Sensitive Dual-Channel Detection of Cyanide by Bis-heteroleptic Ruthenium(II) Complexes Supporting Information for Rapid and Highly Sensitive Dual-Channel Detection of Cyanide by Bis-heteroleptic Ruthenium(II) Complexes Snehadrinarayan Khatua, Debabrata Samanta, Jan W. Bats, Michael Schmittel

More information

Bacterial protease uses distinct thermodynamic signatures for substrate recognition

Bacterial protease uses distinct thermodynamic signatures for substrate recognition Bacterial protease uses distinct thermodynamic signatures for substrate recognition Gustavo Arruda Bezerra, Yuko Ohara-Nemoto, Irina Cornaciu, Sofiya Fedosyuk, Guillaume Hoffmann, Adam Round, José A. Márquez,

More information

Background BIOCHEMISTRY LAB CHE-554. Experiment #1 Spectrophotometry

Background BIOCHEMISTRY LAB CHE-554. Experiment #1 Spectrophotometry BIOCHEMISTRY LAB Experiment #1 Spectrophotometry CHE-554 In day 1 we will use spectrophotometry as an analytical technique using a known extinction coefficient to assess the precision and accuracy of common

More information

A colorimetric and fluorescent turn-on sensor for pyrophosphate. anion based on dicyanomethylene-4h-chromene framework

A colorimetric and fluorescent turn-on sensor for pyrophosphate. anion based on dicyanomethylene-4h-chromene framework Electronic Supplementary Information (ESI) A colorimetric and fluorescent turn-on sensor for pyrophosphate anion based on dicyanomethylene-4h-chromene framework Xiaomei Huang, Zhiqian Guo, Weihong Zhu*,

More information

Amino acids: Optimization in underivatized formula and fragment patterns in LC/ESI-MS analysis. Yoshinori Takano (JAMSTEC)

Amino acids: Optimization in underivatized formula and fragment patterns in LC/ESI-MS analysis. Yoshinori Takano (JAMSTEC) (a) Positive ion mode (ph < 7) Amino acids: ptimization in underivatized formula and fragment patterns in L/ESI-MS analysis R 1 R 2 N + HA R 3 Base Acid R 1 R N H + 2 R 3 + A - Sample [M + H] + (b) Negative

More information

Low-Affinity Zinc Sensor Showing Fluorescence

Low-Affinity Zinc Sensor Showing Fluorescence Supporting Information for Low-Affinity Zinc Sensor Showing Fluorescence Responses with Minimal Artifacts Xinhao Yan, a Jin Ju Kim, b Hey Sun Jeong, c Yu Kyung Moon, b Yoon Kyung Cho, c Soyeon Ahn, a Sang

More information

Phosphorescent chemosensor for Hg 2+ and acetonitrile based on iridium(iii) complex

Phosphorescent chemosensor for Hg 2+ and acetonitrile based on iridium(iii) complex Supporting Information for Phosphorescent chemosensor for Hg 2+ and acetonitrile based on iridium(iii) complex Qun-bo Mei, * a Yuan-hui Guo, a Bi-hai Tong, b Jie-a Weng, a Bin Zhang, a and Wei Huang* a

More information

Supporting Information

Supporting Information Supporting Information A Highly Selective Fluorescence Turn-on Sensor for Cysteine/Homocysteine and its Application in Bioimaging Meng Zhang, Mengxiao Yu, Fuyou Li,*, Minwei Zhu, Manyu Li, Yanhong Gao,

More information

Supplementary Information

Supplementary Information Supplementary Information A fluorescent turn-on probe for bisulfite based on hydrogen bond-inhibited C=N isomerization mechanism Yuan-Qiang Sun, Pi Wang, Jing Liu, Jingyu Zhang and Wei Guo* School of Chemistry

More information

Diastereomeric resolution directed towards chirality. determination focussing on gas-phase energetics of coordinated. sodium dissociation

Diastereomeric resolution directed towards chirality. determination focussing on gas-phase energetics of coordinated. sodium dissociation Supplementary Information Diastereomeric resolution directed towards chirality determination focussing on gas-phase energetics of coordinated sodium dissociation Authors: samu Kanie*, Yuki Shioiri, Koji

More information

Packing of Secondary Structures

Packing of Secondary Structures 7.88 Lecture Notes - 4 7.24/7.88J/5.48J The Protein Folding and Human Disease Professor Gossard Retrieving, Viewing Protein Structures from the Protein Data Base Helix helix packing Packing of Secondary

More information

Electronic Supplementary Information for

Electronic Supplementary Information for Electronic Supplementary Material (ESI) for Organic & Biomolecular Chemistry. This journal is The Royal Society of Chemistry 2014 Electronic Supplementary Information for A colorimetric and ratiometric

More information

Investigation of Cation Binding and Sensing by new Crown Ether core substituted Naphthalene Diimide systems

Investigation of Cation Binding and Sensing by new Crown Ether core substituted Naphthalene Diimide systems Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 218 Supplementary Material Investigation

More information

Peptides And Proteins

Peptides And Proteins Kevin Burgess, May 3, 2017 1 Peptides And Proteins from chapter(s) in the recommended text A. Introduction B. omenclature And Conventions by amide bonds. on the left, right. 2 -terminal C-terminal triglycine

More information

7.012 Problem Set 1. i) What are two main differences between prokaryotic cells and eukaryotic cells?

7.012 Problem Set 1. i) What are two main differences between prokaryotic cells and eukaryotic cells? ame 7.01 Problem Set 1 Section Question 1 a) What are the four major types of biological molecules discussed in lecture? Give one important function of each type of biological molecule in the cell? b)

More information

Structure and evolution of the spliceosomal peptidyl-prolyl cistrans isomerase Cwc27

Structure and evolution of the spliceosomal peptidyl-prolyl cistrans isomerase Cwc27 Acta Cryst. (2014). D70, doi:10.1107/s1399004714021695 Supporting information Volume 70 (2014) Supporting information for article: Structure and evolution of the spliceosomal peptidyl-prolyl cistrans isomerase

More information

Supporting Information

Supporting Information Supporting Information Applying arbon Dots-Metal Ions Ensembles as a Multichannel Fluorescent Sensor Array: Detection and Discrimination of Phosphate Anions Shan Sun,, Kai Jiang, Sihua Qian, Yuhui Wang,

More information

Supplementary Figure 3 a. Structural comparison between the two determined structures for the IL 23:MA12 complex. The overall RMSD between the two

Supplementary Figure 3 a. Structural comparison between the two determined structures for the IL 23:MA12 complex. The overall RMSD between the two Supplementary Figure 1. Biopanningg and clone enrichment of Alphabody binders against human IL 23. Positive clones in i phage ELISA with optical density (OD) 3 times higher than background are shown for

More information

Properties of amino acids in proteins

Properties of amino acids in proteins Properties of amino acids in proteins one of the primary roles of DNA (but not the only one!) is to code for proteins A typical bacterium builds thousands types of proteins, all from ~20 amino acids repeated

More information

A water-soluble and fast-response mitochondria-targeted fluorescent

A water-soluble and fast-response mitochondria-targeted fluorescent Electronic Supplementary Material (ESI) for ChemComm. This journal is The Royal Society of Chemistry 2016 Electronic Supplementary Information (ESI) A water-soluble and fast-response mitochondria-targeted

More information

NMR Assignments using NMRView II: Sequential Assignments

NMR Assignments using NMRView II: Sequential Assignments NMR Assignments using NMRView II: Sequential Assignments DO THE FOLLOWING, IF YOU HAVE NOT ALREADY DONE SO: For Mac OS X, you should have a subdirectory nmrview. At UGA this is /Users/bcmb8190/nmrview.

More information

Supporting Information. Enlarging the π System of Phosphorescent (C^C*) Cyclometalated Platinum(II) NHC Complexes

Supporting Information. Enlarging the π System of Phosphorescent (C^C*) Cyclometalated Platinum(II) NHC Complexes Supporting Information Enlarging the π System of Phosphorescent (C^C*) Cyclometalated Platinum(II) NHC Complexes Alexander Tronnier #, Alexander Pöthig, # Stefan Metz $, Gerhard Wagenblast $, Ingo Münster

More information

Supplement information

Supplement information Electronic Supplementary Material (ESI) for Physil Chemistry Chemil Physics. This journal is the Owner Societies 216 Supplement information Fullerenol C 6 (OH) 16 prevents amyloid fibrillization of Aβ

More information

Supporting Information. for

Supporting Information. for Supporting Information for Near-Infrared Fluorescent Turn-On Probe with a Remarkable Large Stokes Shift for Imaging Selenocysteine in Living Cells and Animals Weiyong Feng, Meixing Li, Yao Sun, and Guoqiang

More information

Decreasing the Viscosity in CO 2 Capture by Amino-functionalized Ionic Liquids through the Formation of Intramolecular Hydrogen Bond

Decreasing the Viscosity in CO 2 Capture by Amino-functionalized Ionic Liquids through the Formation of Intramolecular Hydrogen Bond Electronic Supplementary Information Decreasing the Viscosity in CO 2 Capture by Amino-functionalized Ionic Liquids through the Formation of Intramolecular Hydrogen Bond Xiao Y. Luo, Xi Fan, Gui L. Shi,

More information

Solutions In each case, the chirality center has the R configuration

Solutions In each case, the chirality center has the R configuration CAPTER 25 669 Solutions 25.1. In each case, the chirality center has the R configuration. C C 2 2 C 3 C(C 3 ) 2 D-Alanine D-Valine 25.2. 2 2 S 2 d) 2 25.3. Pro,, Trp, Tyr, and is, Trp, Tyr, and is Arg,

More information

Supplementary Information

Supplementary Information Electronic Excited States of Tungsten(0) Arylisocyanides Hana Kvapilová, a,b Wesley Sattler, c Aaron Sattler, c Igor V. Sazanovich, d Ian P. Clark, d Michael Towrie, d Harry B. Gray, c, * Stanislav Záliš,

More information

FW 1 CDR 1 FW 2 CDR 2

FW 1 CDR 1 FW 2 CDR 2 Supplementary Figure 1 Supplementary Figure 1: Interface of the E9:Fas structure. The two interfaces formed by V H and V L of E9 with Fas are shown in stereo. The Fas receptor is represented as a surface

More information

Supplementary figure 1. Comparison of unbound ogm-csf and ogm-csf as captured in the GIF:GM-CSF complex. Alignment of two copies of unbound ovine

Supplementary figure 1. Comparison of unbound ogm-csf and ogm-csf as captured in the GIF:GM-CSF complex. Alignment of two copies of unbound ovine Supplementary figure 1. Comparison of unbound and as captured in the GIF:GM-CSF complex. Alignment of two copies of unbound ovine GM-CSF (slate) with bound GM-CSF in the GIF:GM-CSF complex (GIF: green,

More information

Supporting Information. for A Water-Soluble Switching on Fluorescent Chemosensor of. Selectivity to Cd 2+

Supporting Information. for A Water-Soluble Switching on Fluorescent Chemosensor of. Selectivity to Cd 2+ Supporting Information for A Water-Soluble Switching on Fluorescent Chemosensor of Selectivity to Cd 2+ Weimin Liu, a Liwei Xu, a Ruilong Sheng, a Pengfei Wang,*,a Huaping Li*,b and Shikang Wu a a Laboratory

More information

Excited States in Organic Light-Emitting Diodes

Excited States in Organic Light-Emitting Diodes Excited States in Organic Light-Emitting Diodes The metal-to-ligand charge transfer (MLCT) excited states of d 6 π coordination compounds have emerged as the most efficient for solar harvesting and sensitization

More information

Electronic Supplementary Information

Electronic Supplementary Information Electronic Supplementary Material (ESI) for New Journal of Chemistry. This journal is The Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2018 Electronic Supplementary Information

More information

Supporting Information. BODIPY-based Ratiometric Fluorescent Probe for Sensitive and Selective Sensing of Cyanide Ion

Supporting Information. BODIPY-based Ratiometric Fluorescent Probe for Sensitive and Selective Sensing of Cyanide Ion Supporting Information BODIPY-based Ratiometric Fluorescent Probe for Sensitive and Selective Sensing of Cyanide Ion Jingtuo Zhang, a Shilei Zhu, a Loredana Valenzano, a Fen-Tair Luo, b and Haiying Liu*

More information

The translation machinery of the cell works with triples of types of RNA bases. Any triple of RNA bases is known as a codon. The set of codons is

The translation machinery of the cell works with triples of types of RNA bases. Any triple of RNA bases is known as a codon. The set of codons is Relations Supplement to Chapter 2 of Steinhart, E. (2009) More Precisely: The Math You Need to Do Philosophy. Broadview Press. Copyright (C) 2009 Eric Steinhart. Non-commercial educational use encouraged!

More information

Electronic Supplementary Information for

Electronic Supplementary Information for Electronic Supplementary Material (ESI) for Metallomics. This journal is The Royal Society of Chemistry 2015 Electronic Supplementary Information for Metal ion mediated transition from random coil to β-sheet

More information

Supporting Information

Supporting Information Electronic Supplementary Material (ESI) for RSC Advances. This journal is The Royal Society of Chemistry 2014 Supporting Information Performance comparison of two cascade reaction models in fluorescence

More information

Postsynthetic modification of unprotected peptides via S-tritylation reaction

Postsynthetic modification of unprotected peptides via S-tritylation reaction Supporting Information Postsynthetic modification of unprotected peptides via S-tritylation reaction Masayoshi Mochizuki, Hajime Hibino and Yuji Nishiuchi *,, SAITO Research Center, Peptide Institute,

More information

MARK SCHEME for the October/November 2012 series 9701 CHEMISTRY

MARK SCHEME for the October/November 2012 series 9701 CHEMISTRY CAMBRIDGE INTERNATIONAL EXAMINATIONS GCE Advanced Level MARK SCHEME for the October/November 2012 series 9701 CHEMISTRY 9701/43 Paper 4 (A2 Structured Questions), maximum raw mark 100 This mark scheme

More information

Content : Properties of amino acids.. Separation and Analysis of Amino Acids

Content : Properties of amino acids.. Separation and Analysis of Amino Acids قسم الكيمياء الحيوية.دولت على سالمه د. استاذ الكيمياء الحيوية ٢٠١٥-٢٠١٤ المحاضرة الثانية 1 Content : Properties of amino acids.. Separation and Analysis of Amino Acids 2 3 Physical Properties of Amino

More information

Biotin-guided fluorescent-peptide drug delivery system for cancer

Biotin-guided fluorescent-peptide drug delivery system for cancer Electronic Supplementary Material (ESI) for ChemComm. This journal is The Royal Society of Chemistry 2014 Supporting Information For Biotin-guided fluorescent-peptide drug delivery system for cancer Taeyoung

More information

Structural insights into energy regulation of light-harvesting complex from spinach CP29

Structural insights into energy regulation of light-harvesting complex from spinach CP29 SUPPLEMENTARY INFORMATION Structural insights into energy regulation of light-harvesting complex from spinach CP29 Xiaowei Pan 1, Mei Li 1, Tao Wan 1,2, Longfei Wang 1,2, Chenjun Jia 1,2, Zhiqiang Hou

More information

Supplementary Information. Affinity Selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors

Supplementary Information. Affinity Selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors Supplementary Information Affinity Selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants Shinya Oishi,* a Kentaro Watanabe, a Saori Ito,

More information

Supporting Information

Supporting Information Supporting Information Micelle-Triggered b-hairpin to a-helix Transition in a 14-Residue Peptide from a Choline-Binding Repeat of the Pneumococcal Autolysin LytA HØctor Zamora-Carreras, [a] Beatriz Maestro,

More information

The sensing behaviour of S1 was evaluated in following two different media; 1. In acetonitrile: 2. In aqueous solution:

The sensing behaviour of S1 was evaluated in following two different media; 1. In acetonitrile: 2. In aqueous solution: The union of merely hundred plus elements lead to billions of molecules with varieties of properties. This union takes place at the level of electrons between two bonding entities i.e. atoms. This union

More information

Singlet Photoreactivity of 3-Methyl-2-phenyl-2Hazirine

Singlet Photoreactivity of 3-Methyl-2-phenyl-2Hazirine 10.1071/CH16604_AC CSIRO 2017 Australian Journal of Chemistry 2017, 70(4), 413-420 SUPPLEMENTARY MATERIAL Singlet Photoreactivity of 3-Methyl-2-phenyl-2Hazirine Geethika K. Weragoda,a Anushree Das, a Sujan

More information

Amino Acids and Peptides

Amino Acids and Peptides Amino Acids Amino Acids and Peptides Amino acid a compound that contains both an amino group and a carboxyl group α-amino acid an amino acid in which the amino group is on the carbon adjacent to the carboxyl

More information

Deep-red and near-infrared xanthene dyes for rapid live cell imaging

Deep-red and near-infrared xanthene dyes for rapid live cell imaging Deep-red and near-infrared xanthene dyes for rapid live cell imaging Guangle Niu,, Weimin Liu,*, Bingjiang Zhou,, Hongyan Xiao, Hongyan Zhang, Jiasheng Wu, Jiechao Ge, and Pengfei Wang Key Laboratory of

More information

Supporting information to: Time-resolved observation of protein allosteric communication. Sebastian Buchenberg, Florian Sittel and Gerhard Stock 1

Supporting information to: Time-resolved observation of protein allosteric communication. Sebastian Buchenberg, Florian Sittel and Gerhard Stock 1 Supporting information to: Time-resolved observation of protein allosteric communication Sebastian Buchenberg, Florian Sittel and Gerhard Stock Biomolecular Dynamics, Institute of Physics, Albert Ludwigs

More information

C CH 3 N C COOH. Write the structural formulas of all of the dipeptides that they could form with each other.

C CH 3 N C COOH. Write the structural formulas of all of the dipeptides that they could form with each other. hapter 25 Biochemistry oncept heck 25.1 Two common amino acids are 3 2 N alanine 3 2 N threonine Write the structural formulas of all of the dipeptides that they could form with each other. The carboxyl

More information

Viewing and Analyzing Proteins, Ligands and their Complexes 2

Viewing and Analyzing Proteins, Ligands and their Complexes 2 2 Viewing and Analyzing Proteins, Ligands and their Complexes 2 Overview Viewing the accessible surface Analyzing the properties of proteins containing thousands of atoms is best accomplished by representing

More information

CHEMISTRY ATAR COURSE DATA BOOKLET

CHEMISTRY ATAR COURSE DATA BOOKLET CHEMISTRY ATAR COURSE DATA BOOKLET 2018 2018/2457 Chemistry ATAR Course Data Booklet 2018 Table of contents Periodic table of the elements...3 Formulae...4 Units...4 Constants...4 Solubility rules for

More information

Secondary Structure. Bioch/BIMS 503 Lecture 2. Structure and Function of Proteins. Further Reading. Φ, Ψ angles alone determine protein structure

Secondary Structure. Bioch/BIMS 503 Lecture 2. Structure and Function of Proteins. Further Reading. Φ, Ψ angles alone determine protein structure Bioch/BIMS 503 Lecture 2 Structure and Function of Proteins August 28, 2008 Robert Nakamoto rkn3c@virginia.edu 2-0279 Secondary Structure Φ Ψ angles determine protein structure Φ Ψ angles are restricted

More information