Method for the determination of 1,3-butadiene

Size: px
Start display at page:

Download "Method for the determination of 1,3-butadiene"

Transcription

1 Federation of the Employment Accidents Insurance Institutions of Germany (Hauptverband der Berufsgenossenschaften) Centre for Accident Prevention and Occupational Medicine Alte Heerstraße 111, Sankt Augustin Expert Committee Chemistry Carcinogenic substances Order number: BGI E Established methods Issue: May 1985 Method for the determination of 1,3-butadiene Method tested and recommended by the Berufsgenossenschaften for the determination of 1,3-butadiene in working areas. 1 CONTINUOUS PROCEDURE Stationary process gas chromatographs can be used to monitor the concentration of 1,3-butadiene in working areas. 2 DISCONTINUOUS PROCEDURE For the assessment of working areas, both personal and stationary sampling are possible. Sampling with a pump and adsorption on activated carbon, head-space gas chromatography. Air MonitoringMethods,Vol. 7

2 Analytical Methods Air MonitoringMethods,Vol CONTINUOUS PROCEDURE Process gas chromatography for stationary sampling Principle: A measured air volume is added to a stream of carrier gas and drawn through a GC column. Depending on the number and type of accompanying components, some of which may also be determined, further columns are necessary to separate the 1,3-butadiene. To shorten the time needed for analysis, the stream of carrier gas is diverted onto these columns in a suitable manner. The 1,3-butadiene is determined with a flame ionisation detector (FID). Technical data: Smallest measuring range: 0 ¼ 20 ml/m 3 (ppm). Quantification limit: 1.0 ml/m 3 (ppm) = 2.3 mg/m 3 1,3-butadiene. Selectivity: Selective determination possible, if a suitable column is used. Time needed for each determination: Materials: Supplier: 3 ¼ 10 minutes (depending on the accompanying components such as acrylonitrile and styrene) source of pneumatic energy, purified or synthetic air, hydrogen, carrier gas: nitrogen. Siemens AG, Karlsruhe.

3 33 Air MonitoringMethods,Vol. 7 1,3-Butadiene 2 DISCONTINUOUS PROCEDURE Sampling with a pump and adsorption on activated carbon, headspace gas chromatography Principle: With a pump a measured air volume is drawn through an adsorption tube with activated carbon. The adsorbed 1,3-butadiene is desorbed with a non-volatile solvent and determined by headspace gas chromatography (HSGC). Technical data: Quantification limit: Under the conditions found in practice, the relative quantification limit is 0.5 ml/m 3 (ppm) = 1.1 mg/m 3 1,3-butadiene for a 16-litre air sample. This corresponds to 18 µg 1,3-butadiene per activated carbon tube. Selectivity: When interfering components are present, the values determined may be too high. Interferences can generally be eliminated by selecting a different column. Advantages: Personal sampling and selective determination possible. Disadvantages: No indication of peak concentrations, time-consuming. Apparatus: Pump, gas meter or flow meter, adsorption tubes with activated carbon, head-space gas chromatograph with flame ionisation detector (FID).

4 Analytical Methods Air MonitoringMethods,Vol Detailed description of the method Contents 1 Summary 2 Equipment, chemicals and solutions 2.1 Equipment 2.2 Chemicals 2.3 Solutions 3 Sampling 4 Analytical determination 4.1 Sample preparation and analysis 4.2 Operating conditions for gas chromatography 5 Evaluation 5.1 Calibration 5.2 Calculation of the analytical result 6 Reliability of the method 6.1 Accuracy 6.2 Quantification limit 6.3 Selectivity 6.4 Recovery 7 Discussion 8 Suppliers 9 References 1 Summary This method permits the determination of 1,3-butadiene concentrations in working areas averaged over the sampling time after personal or stationary sampling. With a pump carried by a person or used in a stationary position, a measured air volume is drawn through a glass tube filled with activated carbon. The butadiene is then eluted with a non-volatile solvent and determined by head-space gas chromatography according to the internal standard method. Under the conditions found in practice, the relative detection limit is 1.1 mg/m 3 = 0.5 ml/m 3 (ppm) 1,3-butadiene for a 16-litre air sample. This corresponds to 18 µg 1,3- butadiene per activated carbon tube.

5 35 Air MonitoringMethods,Vol. 7 1,3-Butadiene 2 Equipment, chemicals and solutions 2.1 Equipment For sampling and sample preparation: Pump with gas meter or flow meter Sample vials with PTFE* 1 -coated septa and aluminium caps 30 ml, 10 ml Crimper Adsorption tubes filled with activated carbon (standardized, consisting of two zones filled with activated carbon separated by porous polymeric material; see Section 7 discussion) Caps for the opened activated carbon tubes For analysis: Head-space gas chromatograph with flame ionisation detector, automatic injection from the head-space chamber, perhaps with back-flush device Evaluation unit Injection of the sample can also be carried out manually instead of injecting automatically. Gas-tight syringes are required for this. 2.2 Chemicals Butadiene, purity 6 99% Methyl acetate, purity 6 98% (internal standard) N,N-Dimethylacetamide (DMA), GC grade Gases for operating the gas chromatograph: Nitrogen Hydrogen Synthetic air 2.3 Solutions Methyl acetate standard solution: Butadiene/methyl acetate calibration solution: Solution of 50 mg methyl acetate in 100 ml DMA. 50 mg methyl acetate is placed in a 100 ml volumetric flask which is then filled to the mark with DMA. Solution of about 11 mg 1,3-butadiene and 10 mg methyl acetate in 20 ml DMA. About 5 ml gaseous 1,3-butadiene is injected with a gas syringe slowly into the liquid through the septum of a sample vial filled with 20 ml methyl acetate standard solution. 1,3-Butadiene bubbles should not appear at the tip of the * Polytetrafluoroethylene.

6 Analytical Methods Air MonitoringMethods,Vol needle. It should be prevented that 1,3-butadien escapes at the puncture site of the septum. The amount of added 1,3- butadiene is determined by weighing to the nearest 0.1 mg. 3 Sampling An activated carbon tube is opened and connected to the pump. The pump and tube are carried by a person during working hours or used in a stationary position. The flow rate is set at about 2 l/hour. 4 Analytical determination 4.1 Sample preparation and analysis The two zones of the loaded activated carbon tube are each placed in a 10 ml sample vial. 1 ml methyl acetate standard solution and 1 ml DMA are added to each and the sample vials are closed tightly. The closed sample vial with the loaded activated carbon, 1 ml methyl acetate standard solution and 1 ml DMA are heated in the sample thermostat for 30 minutes at 70 8C. The same volume as for calibration (see Section 5.1) is then injected from the headspace chamber into the gas chromatograph and a gas chromatogram is recorded (for operating conditions see Section 4.2). Quantitative evaluation is performed according to the internal standard method using the peak areas or peak heights. To ensure that the DMA, methyl acetate and activated carbon used do not contain any interfering impurities, a gas chromatogram is recorded with the filling of an unloaded activated carbon tube, 1 ml methyl acetate standard solution and 1 ml DMA as described above. 4.2 Operating conditions for gas chromatography. The method was characterized under the following experimental conditions: Apparatus: Head-space gas chromatograph Carlo Erba model 2900 with flame ionisation detector, automatic sampling from the head-space chamber, back-flush device Column: Material: Quartz capillary Length: 30 m Internal diameter: 0.25 mm Stationary phase: Carbowax 20 M

7 37 Air MonitoringMethods,Vol. 7 1,3-Butadiene Temperatures: Sample thermostat: 70 8C Injection device: 90 8C Injector block: 200 8C Column: 70 8C, isothermal Detector: 200 8C Carrier gas: Helium, flow rate 2 ml/min Detector gases: Hydrogen, flow rate 35 ml/min Synthetic air, flow rate 350 ml/min 5 Evaluation 5.1 Calibration The vapour-space of a sample vial containing the filling of an unloaded activated carbon tube, 1 ml butadiene/methyl acetate calibration solution and 1 ml DMA, is analysed under the given GC conditions (see Section 4.2). The calibration factor for butadiene is calculated using the butadiene and methyl acetate peak areas according to equation (1): f ˆ A0 is w0 A 0 w 0 is 1 Where: f calibration factor for butadiene A' is Peak area for methyl acetate A' Peak area for butadiene w' Weight of butadiene in mg in 1 ml of the calibration solution Weight of methyl acetate in mg in 1 ml of the calibration solution w' is 5.2 Calculation of the analytical result The concentration by weight of 1,3-butadiene in the air sample in mg/m 3 is calculated according to equation (2): c w ˆ A w is f 1000 A is V 2 For 20 8C and 1013 mbar the concentration by volume in ml/m 3 is calculated from c w according to the following equation (3): c v ˆ 0:44 c w Where: c w Concentration of 1,3-butadiene in the air sample in mg/m 3 c v Concentration of 1,3-butadiene in the air sample in ml/m 3 (ppm) 3

8 Analytical Methods Air MonitoringMethods,Vol A Peak area for 1,3-butadiene from the sample A is Peak area for methyl acetate from the methyl acetate standard solution w is Weight of methyl acetate in 1 ml of the methyl acetate standard solution V Air sample volume in l f calibration factor for 1,3-butadiene Evaluation using the peak heights can also be carried out as described above. 6 Reliability of the method 6.1 Accuracy For the whole procedure, with a concentration range of 3 ml/m 3 to 8 ml/m 3, the relative standard deviation was calculated from measurements in practice to be 6% with a range of scatter of 12%. 6.2 Quantification limit The quantification limit depends on the type of gas chromatographic detector and the quality of the device. Under the conditions in practice, 18 µg 1,3-butadiene per activated carbon tube can be detected. This corresponds to a 1,3-butadiene concentration of 1.1 mg/m 3 = 0.5 ml/m 3 (ppm) for a 16-litre air sample. 6.3 Selectivity The selectivity of the procedure depends above all on the type of column used. In practice the given capillary column has proved reliable. If there is interference, a column with a different separation phase must be used. 6.4 Recovery Desorption of the 1,3-butadiene with DMA is reproducible. As shown by comparison with calibration solutions, 1,3-butadiene was recovered from test gases almost completely. 7 Discussion Activated carbon tubes (SKC catalogue No. 226±01, filling 100 mg + 50 mg activated carbon) can be used under the given conditions up to a 1,3-butadiene concentration of

9 39 Air MonitoringMethods,Vol. 7 1,3-Butadiene 100 ml/m 3 (ppm). At higher concentrations or high humidity, activated carbon tubes with a greater filling of activated carbon (about 1 g) should be used. These activated carbon tubes can also be used for greater flow rates during sampling. The loaded activated carbon tubes closed with caps can be stored at room temperature for 5 days. The peak area correction factor is constant over a wide range of weight ratios of 1,3-butadiene: methyl acetate (0.5 :1 to 50 : 1) under the conditions described in Section 4. The determination of 1,3-butadiene has also proved reliable with the use of ± benzyl alcohol as elution agent (instead of N,N-dimethylacetamide) and ± head-space gas chromatography with a packed column (instead of capillary column). Column: stainless steel, length 2 m, internal diameter 3 mm, filled with GP 80/100 Carbopack C coated with 0.19% picric acid. 8 Suppliers Pump: Activated carbon tube, NIOSH: Dråger, type B Head-space gas chromatograph: e. g. Du Pont Instruments, supplier in Germany: DEHA-Haan & Wittmer GmbH, Friolzheim e. g. Chrompack Deutschland, Mçllheim Compur Electronic GmbH, Munich Fleischhacker KG, Schwerte/Ruhr Gçnter Karl ohg, Geisenheim e. g. Drågerwerk AG, Lçbeck e. g. Bodenseewerk Perkin Elmer & Co GmbH, Ûberlingen Carlo Erba, supplier in Germany: Erba Science, Hofheim/Ts Siemens AG, Karlsruhe 9 References Hachenberg H, Schmidt AP (1979) Gas chromatographic head space analysis. London, Philadelphia, Rheine: Heyden and Sons.

Methods for the determination of vinyl chloride

Methods for the determination of vinyl chloride Federation of the Employment Accidents Insurance Institutions of Germany (Hauptverband der Berufsgenossenschaften) Centre for Accident Prevention and Occupational Medicine Alte Heerstraße 111, 53757 Sankt

More information

Methods for the determination of ethylene oxide

Methods for the determination of ethylene oxide Federation of the Employment Accidents Insurance Institutions of Germany (Hauptverband der Berufsgenossenschaften) Centre for Accident Prevention and Occupational Medicine Alte Heerstraße 111, 53757 Sankt

More information

Method for the determination of dimethyl sulfate

Method for the determination of dimethyl sulfate German Social Accident Insurance Deutsche Gesetzliche Unfallversicherung Analytical Subcommittee of the Chemistry Board of Experts* Carcinogenic substances Order number: BGI 505-7-05 Established methods:

More information

ANALYTICAL METHOD DETERMINATION OF VOLATILE ALDEHYDES IN AMBIENT AIR Page 1 of 11 Air sampling and analysis

ANALYTICAL METHOD DETERMINATION OF VOLATILE ALDEHYDES IN AMBIENT AIR Page 1 of 11 Air sampling and analysis DETERMINATION OF VOLATILE ALDEHYDES IN AMBIENT AIR Page 1 of 11 Replaces: Dated: Author: Date: AM-No.: New New Nils Arne Jentoft 18.06.2014 0 CHANGES This procedure is new. 1 SCOPE This document describes

More information

VINYL CHLORIDE. Recommended by NIOSH, partially evaluated by OSHA Laboratory.

VINYL CHLORIDE. Recommended by NIOSH, partially evaluated by OSHA Laboratory. VINYL CHLORIDE Method no.: 04 Matrix: Air Target concentration: 3 1 ppm (2.5 mg/m ) (OSHA PEL) Procedure: Collection on charcoal (two-tubes in-series), desorption with carbon disulfide, analysis by gas

More information

Gas Chromatography. Presented By Mr. Venkateswarlu Mpharm KTPC

Gas Chromatography. Presented By Mr. Venkateswarlu Mpharm KTPC Gas Chromatography Gas Chromatography Presented By Mr. Venkateswarlu Mpharm KTPC What is Gas Chromatography? It is also known as Gas-Liquid Chromatography (GLC) GAS CHROMATOGRAPHY Separation of gaseous

More information

Simultaneous Estimation of Residual Solvents (Isopropyl Alcohol and Dichloromethane) in Dosage Form by GC-HS-FID

Simultaneous Estimation of Residual Solvents (Isopropyl Alcohol and Dichloromethane) in Dosage Form by GC-HS-FID Asian Journal of Chemistry Vol. 21, No. 3 (2009), 1739-1746 Simultaneous Estimation of Residual Solvents (Isopropyl Alcohol and Dichloromethane) in Dosage Form by GC-HS-FID PRAVEEN KUMAR BALIYAN*, R.P.

More information

METHOD: 1403, Issue 3 EVALUATION: FULL Issue 1: 15 August 1990 Issue 3: 15 March 2003

METHOD: 1403, Issue 3 EVALUATION: FULL Issue 1: 15 August 1990 Issue 3: 15 March 2003 ALCOHOLS IV 1403 (1) HOCH 2 CH 2 OCH 3 MW: (1) 76.09 CAS: (1) 109-86-4 RTECS: (1) KL5775000 (2) HOCH 2 CH 2 OCH 2 CH 3 (2) 90.12 (2) 110-80-5 (2) KK8050000 (3) HOCH 2 CH 2 O(CH 2 ) 3 CH 3 (3) 118.17 (3)

More information

Anethole. Gas chromatograhpy determination of trans-anethole in Spirit srinks of viti-vinicultural origin

Anethole. Gas chromatograhpy determination of trans-anethole in Spirit srinks of viti-vinicultural origin OIVMABS15 Anethole. Gas chromatograhpy determination of transanethole in Type II method SCOPE This method is suitable for the determination of transanethole in aniseedflavoured spirit drinks using capillary

More information

Chemistry Gas Chromatography: Separation of Volatile Organics

Chemistry Gas Chromatography: Separation of Volatile Organics Chemistry 3200 Gas chromatography (GC) is an instrumental method for separating volatile compounds in a mixture. A small sample of the mixture is injected onto one end of a column housed in an oven. The

More information

Determination of Volatile Substances Proof of Food Adulteration

Determination of Volatile Substances Proof of Food Adulteration ANALYSIS OF FOOD AND NATURAL PRODUCTS LABORATORY EXERCISE Determination of Volatile Substances Proof of Food Adulteration (method: gas chromatography with mass spectrometric detection) Exercise guarantor:

More information

Magnitudes of Back Diffusion During Long-Term Diffusive Sampling of Volatile Organic Compounds Using Carbotrap and Chromosorb 106

Magnitudes of Back Diffusion During Long-Term Diffusive Sampling of Volatile Organic Compounds Using Carbotrap and Chromosorb 106 Turk J Chem 24 (2000), 131 139. c TÜBİTAK Magnitudes of Back Diffusion During Long-Term Diffusive Sampling of Volatile Organic Compounds Using Carbotrap and Chromosorb 106 Naciye KILIÇ University of Uludağ,

More information

GUIDELINES FOR THE DESIGN OF CHROMATOGRAPHIC ANALYTICAL METHODS INTENDED FOR CIPAC COLLABORATIVE STUDY

GUIDELINES FOR THE DESIGN OF CHROMATOGRAPHIC ANALYTICAL METHODS INTENDED FOR CIPAC COLLABORATIVE STUDY Page 1 of 13 CIPAC/4105/R GUIDELINES FOR THE DESIGN OF CHROMATOGRAPHIC ANALYTICAL METHODS INTENDED FOR CIPAC COLLABORATIVE STUDY Prepared for CIPAC by Dr M J Tandy*, P M Clarke and B White (UK) The rapid

More information

Principles of Gas- Chromatography (GC)

Principles of Gas- Chromatography (GC) Principles of Gas- Chromatography (GC) Mohammed N. Sabir January 2017 10-Jan-17 1 GC is a chromatographic technique utilizes gas as the mobile phase which is usually an inert gas (Hydrogen, Helium, Nitrogen

More information

Gas Chromatography (GC)

Gas Chromatography (GC) Gas Chromatography (GC) Ahmad Aqel Ifseisi Assistant Professor of Analytical Chemistry College of Science, Department of Chemistry King Saud University P.O. Box 2455 Riyadh 11541 Saudi Arabia Office: AA53

More information

Hexane isomers (except n-hexane) and methylcyclopentane

Hexane isomers (except n-hexane) and methylcyclopentane 1 Hexane isomers (except n-hexane) and methylcyclopentane Method number 1 Application Air analysis Analytical principle Gas chromatography Completed in July 2010 Summary This analytical method permits

More information

Chromatography. Gas Chromatography

Chromatography. Gas Chromatography Chromatography Chromatography is essentially the separation of a mixture into its component parts for qualitative and quantitative analysis. The basis of separation is the partitioning of the analyte mixture

More information

METHOD 8030A ACROLEIN AND ACRYLONITRILE BY GAS CHROMATOGRAPHY

METHOD 8030A ACROLEIN AND ACRYLONITRILE BY GAS CHROMATOGRAPHY METHOD 8030A ACROLEIN AND ACRYLONITRILE BY GAS CHROMATOGRAPHY 1.0 SCOPE AND APPLICATION 1.1 Method 8030 is used to determine the concentration of the following volatile organic compounds: Compound Name

More information

637. Thiamethoxam. HPLC method

637. Thiamethoxam. HPLC method 637. Thiamethoxam HPLC method CIPAC Collaborative Trial according to CIPAC Information Sheet N o 293 Dr. Sven Adolph Syngenta Crop Protection Münchwilen AG CH-4333 Münchwilen Switzerland May 212 page 1

More information

Sulfotepp impurities in Chlorpyrifos EC formulations

Sulfotepp impurities in Chlorpyrifos EC formulations Page 1 of 16 Method DAS-AM-01-058 Sulfotepp impurities in Chlorpyrifos EC formulations A. ABSTRACT Method DAS-AM-01-058 has been validated for the analysis of the relevant impurity sulfotepp in chlorpyrifos

More information

CH 2252 Instrumental Methods of Analysis Unit V Gas Chromatography. M. Subramanian

CH 2252 Instrumental Methods of Analysis Unit V  Gas Chromatography.  M. Subramanian CH 2252 Instrumental Methods of Analysis Unit V Gas Chromatography M. Subramanian Assistant Professor Department of Chemical Engineering Sri Sivasubramaniya Nadar College of Engineering Kalavakkam 603

More information

1,2-Dibromoethane (EDB) and 1,2-dibromo-3-chloropropane (DBCP), gas chromatography, microextraction

1,2-Dibromoethane (EDB) and 1,2-dibromo-3-chloropropane (DBCP), gas chromatography, microextraction 1. Application 1,2-Dibromoethane (EDB) and 1,2-dibromo-3-chloropropane (DBCP), gas chromatography, microextraction Parameters and Codes: EDB and DBCP, whole water recoverable, O-3120-90 Parameter (µg/l)

More information

Method for Characterization of Gum Rosin by Capillary Gas Chromatography

Method for Characterization of Gum Rosin by Capillary Gas Chromatography PCA TEST METHOD PCTM 27 Published 1/1 2004 1. Scope Method for Characterization of Gum Rosin by Capillary Gas Chromatography 1.1 These test methods cover the determination of the amounts of certain rosin

More information

HYDROCARBONS, AROMATIC 1501

HYDROCARBONS, AROMATIC 1501 HYDROCARBONS, AROMATIC 1501 FORMULA: Table 1 MW: Table 1 CAS: Table 1 RTECS: Table 1 METHOD: 1501, Issue 3 EVALUATION: Full Issue 1: 15 August 1990 Issue 3: 15 March 2003 OSHA : Table 2 NIOSH: Table 2

More information

Chapter 31 Gas Chromatography. Carrier Gas System

Chapter 31 Gas Chromatography. Carrier Gas System Chapter 31 Gas Chromatography GAS-LIQUID CHROMATOGRAPHY In gas chromatography, the components of a vaporized sample are fractionated as a consequence of being partitioned between a mobile gaseous phase

More information

METHYLTIN CHLORIDES 5526

METHYLTIN CHLORIDES 5526 METHYLTIN CHLORIDES 5526 Formula: Table 1 MW: Table 1 CAS: Table 1 RTECS: Table 1 METHOD: 5526, Issue 1 EVALUATION: FULL Issue 1: 15 March 2003 OSHA : See Table 1 NIOSH: See Table 1 ACGIH: See Table 1

More information

CHAPTER 6 GAS CHROMATOGRAPHY

CHAPTER 6 GAS CHROMATOGRAPHY CHAPTER 6 GAS CHROMATOGRAPHY Expected Outcomes Explain the principles of gas chromatography Able to state the function of each components of GC instrumentation Able to state the applications of GC 6.1

More information

METHOD 8033 ACETONITRILE BY GAS CHROMATOGRAPHY WITH NITROGEN-PHOSPHORUS DETECTION

METHOD 8033 ACETONITRILE BY GAS CHROMATOGRAPHY WITH NITROGEN-PHOSPHORUS DETECTION METHOD 80 ACETONITRILE BY GAS CHROMATOGRAPHY WITH NITROGEN-PHOSPHORUS DETECTION 1.0 SCOPE AND APPLICATION 1.1 Method 80 may be used to determine the concentration of acetonitrile (CAS No. 75-05-8) in aqueous

More information

Validation of. Tetrahydrofuran Using. SKC Passive Sampler Cat. No

Validation of. Tetrahydrofuran Using. SKC Passive Sampler Cat. No Validation of Tetrahydrofuran Using SKC Passive Sampler Cat. No. 575-002 Page 1 of 10 Publication 1841 Issue 1407 Research Report Validation of Tetrahydrofuran Using the SKC Cat. No. 575-002 Passive Sampler

More information

Paints and varnishes Determination of volatile organic compound (VOC) content. Part 2: Gas-chromatographic method

Paints and varnishes Determination of volatile organic compound (VOC) content. Part 2: Gas-chromatographic method Provläsningsexemplar / Preview INTERNATIONAL STANDARD ISO 11890-2 Third edition 2013-03-15 Paints and varnishes Determination of volatile organic compound (VOC) content Part 2: Gas-chromatographic method

More information

ORGANOPHOSPHORUS PESTICIDES 5600

ORGANOPHOSPHORUS PESTICIDES 5600 ORGANOPHOSPHORUS PESTICIDES 5600 Formula: Table 1 MW: Table 1 CAS: Table 1 RTECS: Table 1 METHOD: 5600, Issue 1 EVALUATION: FULL Issue 1: 15 August 1994 OSHA : Table 2 NIOSH: Table 2 ACGIH: Table 2 PROPERTIES:

More information

Gas Chromatography. Chromatography Laboratory Course. Dr. Christian Jungnickel Chromatography Course GC September 2005

Gas Chromatography. Chromatography Laboratory Course. Dr. Christian Jungnickel Chromatography Course GC September 2005 Gas Chromatography Chromatography Laboratory Course The laboratory course experiments General Aim: Gain general experience using a GC Constant Injection technique Temperature variations Qualitative and

More information

Chapter 27: Gas Chromatography

Chapter 27: Gas Chromatography Chapter 27: Gas Chromatography Gas Chromatography Mobile phase (carrier gas): gas (He, N 2, H 2 ) - do not interact with analytes - only transport the analyte through the column Analyte: volatile liquid

More information

Gas Chromatography. Introduction

Gas Chromatography. Introduction Gas Chromatography Introduction 1.) Gas Chromatography Mobile phase (carrier gas) is a gas - Usually N 2, He, Ar and maybe H 2 - Mobile phase in liquid chromatography is a liquid Requires analyte to be

More information

Test Report. Tremco-Illbruck GmbH & Co KG. Product Emissions Test (AgBB/DIBt Test Protocol) Butyl und Bitumenprimer. June 2011

Test Report. Tremco-Illbruck GmbH & Co KG. Product Emissions Test (AgBB/DIBt Test Protocol) Butyl und Bitumenprimer. June 2011 Test Report Tremco-Illbruck GmbH & Co KG Product Emissions Test (AgBB/DIBt Test Protocol) Butyl und Bitumenprimer June 2011 Client: Tremco-Illbruck GmbH & Co KG Von Der Wettern Str. 27 51149 Köln Germany

More information

CIPAC. CIPAC Free relevant impurities methods:

CIPAC. CIPAC Free relevant impurities methods: CIPAC COLLABORATIVE INTERNATIONAL PESTICIDES ANALYTICAL COUNCIL LIMITED Commission Internationale des Méthodes d'analyse des Pesticides (CIMAP) CIPAC Free relevant impurities methods: Methods for relevant

More information

Analysis of Trace (mg/kg) Thiophene in Benzene Using Two-Dimensional Gas Chromatography and Flame Ionization Detection Application

Analysis of Trace (mg/kg) Thiophene in Benzene Using Two-Dimensional Gas Chromatography and Flame Ionization Detection Application Analysis of Trace (mg/kg) Thiophene in Using Two-Dimensional Gas Chromatography and Flame Ionization Detection Application Petrochemical Authors James D. McCurry and Bruce D. Quimby Agilent Technologies

More information

PRINCIPLES AND APPLICATION OF CHROMATOGRAPHY. Dr. P. Jayachandra Reddy Mpharm PhD Principal & professor KTPC

PRINCIPLES AND APPLICATION OF CHROMATOGRAPHY. Dr. P. Jayachandra Reddy Mpharm PhD Principal & professor KTPC PRINCIPLES AND APPLICATION OF CHROMATOGRAPHY Dr. P. Jayachandra Reddy Mpharm PhD Principal & professor KTPC CHROMATOGRAPHY Laboratory technique for the Separation of mixtures Chroma -"color" and graphein

More information

H 3 CO H 3 CO S CH 3

H 3 CO H 3 CO S CH 3 FENITROTHION 35 H 3 CO P H 3 CO S O CH 3 NO 2 ISO common name Chemical name Fenitrothion O,O-Dimethyl O-4-nitro-m-tolyl phosphorothioate (IUPAC) O,O-Dimethyl O-(3-methyl-4-nitrophenyl)- phosphorothioate

More information

Introduction to Gas Chromatography

Introduction to Gas Chromatography Introduction to Gas Chromatography 31-1 Objectives To know what is chromatography To understand the mechanism of compound separation To know the basic of gas chromatography system 31-2 Chromatography Definition

More information

OPTIMISATION OF SOLID PHASE MICROEXTRACTION (SPME) CONDITIONS FOR HEADSPACE ANALYSIS OF ORGANOPHOSPHATE PESTICIDES IN WHOLE BLOOD

OPTIMISATION OF SOLID PHASE MICROEXTRACTION (SPME) CONDITIONS FOR HEADSPACE ANALYSIS OF ORGANOPHOSPHATE PESTICIDES IN WHOLE BLOOD OPTIMISATION OF SOLID PHASE MICROEXTRACTION (SPME) CONDITIONS FOR HEADSPACE ANALYSIS OF ORGANOPHOSPHATE PESTICIDES IN WHOLE BLOOD Kamarruddin ASRI 1, Robert A. ANDERSON 2 1 Department of Chemistry, Jalan

More information

High Performance Liquid Chromatography

High Performance Liquid Chromatography High Performance Liquid Chromatography What is HPLC? It is a separation technique that involves: Injection of small volume of liquid sample Into a tube packed with a tiny particles (stationary phase).

More information

Technical Procedure for Concentration Determination of Methamphetamine in Liquids via HPLC

Technical Procedure for Concentration Determination of Methamphetamine in Liquids via HPLC Technical Procedure for Concentration Determination of 1.0 Purpose This procedure specifies the required elements for the preparation and use of the Agilent 1100/1200 series High Performance Liquid Chromatograph

More information

Chromatographic Methods of Analysis Section: 5 Gas Chromatography (GC) Prof. Tarek A. Fayed

Chromatographic Methods of Analysis Section: 5 Gas Chromatography (GC) Prof. Tarek A. Fayed Chromatographic Methods of Analysis Section: 5 Gas Chromatography (GC) Prof. Tarek A. Fayed Gas Chromatography (GC) In gas chromatography, the sample is vaporized and injected onto the head of a chromatographic

More information

FORMALDEHYDE by GC 2541

FORMALDEHYDE by GC 2541 FORMALDEHYDE by GC 2541 H 2 C=0 MW: 30.03 CAS: 50-00-0 RTECS: LP8925000 METHOD: 2541, Issue 2 EVALUATION: PARTIAL Issue 1: 15 May 1989 Issue 2: 15 August 1994 OSHA : NIOSH: ACGIH: 0.75 ppm; 2 ppm STEL

More information

A STUDY OF VOLATILE ORGANIC CARBON POLLUTION ON A UNIVERSITY CAMPUS DUE TO TRAFFIC

A STUDY OF VOLATILE ORGANIC CARBON POLLUTION ON A UNIVERSITY CAMPUS DUE TO TRAFFIC A STUDY OF VOLATILE ORGANIC CARBON POLLUTION ON A UNIVERSITY CAMPUS DUE TO TRAFFIC Aysel T. ATIMTAY Middle East Technical University, Environmental Engineering Department, 06531 Ankara Turkey (aatimtay@metu.edu.tr)

More information

Chapter 11 Conventional Gas Chromatography

Chapter 11 Conventional Gas Chromatography Chapter 11 Conventional Gas Chromatography Gas Chromatography GC is the first instrumental chromatographic method developed commercially It is relatively easy to introduce a stable flow and pressure for

More information

RESOLUTION OENO 33/2004 DETERMINATION OF SHIKIMIC ACID IN WINE BY HPLC AND UV-DETECTION

RESOLUTION OENO 33/2004 DETERMINATION OF SHIKIMIC ACID IN WINE BY HPLC AND UV-DETECTION DETERMINATION OF SHIKIMIC ACID IN WINE BY HPLC AND UV-DETECTION The GENERAL ASSEMBLY, Considering Article paragraph iv of the agreement establishing the International organisation of vine and wine Upon

More information

Gas Chromatography. A schematic diagram of a gas chromatograph

Gas Chromatography. A schematic diagram of a gas chromatograph Gas Chromatography In gas liquid chromatography (GLC) partition of solutes occurs between a mobile gas phase (the "carrier gas") and a stationary liquid phase present in the column. The gas-phase concentration

More information

TDTS. Keywords. Introduction. TD Operation; Calibration; Impedance; Discrimination

TDTS.   Keywords. Introduction. TD Operation; Calibration; Impedance; Discrimination Thermal Desorption Technical Support Note 75: Liquid standard injection, tube impedance and other factors which may cause discrimination during the calibration of thermal desorption methods Keywords TD

More information

Trace analysis of mesityl oxide and diacetone alcohol in pharmaceuticals by capillary gas chromatography with flame ionization detection

Trace analysis of mesityl oxide and diacetone alcohol in pharmaceuticals by capillary gas chromatography with flame ionization detection Trade Science Inc. September 2009 Volume 8 Issue 3 ACAIJ, 8(3) 2009 [346-349] Trace analysis of mesityl oxide and diacetone alcohol in pharmaceuticals by capillary gas chromatography with flame ionization

More information

7 INSTRUMENTAL CHROMATOGRAPHY

7 INSTRUMENTAL CHROMATOGRAPHY 7 INSTRUMENTAL CHROMATOGRAPHY 7.1 Introduction There are two forms of chromatography, very widely used in analytical laboratories, which rely on electronic control of the process and detection of the species.

More information

Gas chromatography. Advantages of GC. Disadvantages of GC

Gas chromatography. Advantages of GC. Disadvantages of GC Advantages of GC Gas chromatography Fast analysis, typically minutes Effi cient, providing high resolution Sensitive, easily detecting ppm and often ppb Nondestructive, making possible on - line coupling;

More information

Headspace Technology for GC and GC/MS: Features, benefits & applications

Headspace Technology for GC and GC/MS: Features, benefits & applications Headspace Technology for GC and GC/MS: Features, benefits & applications Karima Baudin Oct 2015 Why use Headspace? Very Simple no to minimum sample prep Robust enhance uptime Non-detectable carry-over

More information

Date 02/24/96 Page 1 Revison 4.0 OKLAHOMA DEPARTMENT OF ENVIRONMENTAL QUALITY METHODS 8020/8015 (MODIFIED) GASOLINE RANGE ORGANICS (GRO)

Date 02/24/96 Page 1 Revison 4.0 OKLAHOMA DEPARTMENT OF ENVIRONMENTAL QUALITY METHODS 8020/8015 (MODIFIED) GASOLINE RANGE ORGANICS (GRO) OKLAHOMA DEPARTMENT OF ENVIRONMENTAL QUALITY 1. SCOPE AND APPLICATION: METHODS 8020/8015 (MODIFIED) GASOLINE RANGE ORGANICS (GRO) Date 02/24/96 Page 1 1.1. This method is designed to measure the concentration

More information

Tar & (SPA) tar analysis

Tar & (SPA) tar analysis Tar & (SPA) tar analysis Truls Liliedahl Chemical Technology School of Chemical Science and Engineering Royal Institute of Technology (KTH) Stockholm, Sweden Tar when gasifying biomass Gasification at

More information

TECHNICAL BRODIFACOUM

TECHNICAL BRODIFACOUM BRODIFACOUM Full specification: Approved 10 December 1999 1. Specification 1.1 Description The material shall consist of brodifacoum together with related manufacturing impurities and shall be in the form

More information

Atmospheric Analysis Gases. Sampling and analysis of gaseous compounds

Atmospheric Analysis Gases. Sampling and analysis of gaseous compounds Atmospheric Analysis Gases Sampling and analysis of gaseous compounds Introduction - External environment (ambient air) ; global warming, acid rain, introduction of pollutants, etc - Internal environment

More information

Abstract: An minimalist overview of chromatography for the person who would conduct chromatographic experiments, but not design experiments.

Abstract: An minimalist overview of chromatography for the person who would conduct chromatographic experiments, but not design experiments. Chromatography Primer Abstract: An minimalist overview of chromatography for the person who would conduct chromatographic experiments, but not design experiments. At its heart, chromatography is a technique

More information

ChromTech options for PAL systems

ChromTech options for PAL systems ChromTech options for PAL systems SPDE features full automation for dynamic sample extraction, desorption and analysis using the CTC Combi PAL. Most of our customers use SPDE for food and flavor research,

More information

PA-DEP 3686, Rev. 1. Light Hydrocarbons in Aqueous Samples via Headspace and Gas Chromatography with Flame Ionization Detection (GC/FID)

PA-DEP 3686, Rev. 1. Light Hydrocarbons in Aqueous Samples via Headspace and Gas Chromatography with Flame Ionization Detection (GC/FID) Light Hydrocarbons in Aqueous Samples via Headspace and Gas Chromatography with Flame Ionization Detection (GC/FID) Table of Contents Section 1: Summary of Method Section 2: Scope and Application Section

More information

BRIEFING. Pharmacopeial Discussion Group Sign Off Document Attributes EP JP USP Definition Loss on drying Readily carbonizable substances

BRIEFING. Pharmacopeial Discussion Group Sign Off Document Attributes EP JP USP Definition Loss on drying Readily carbonizable substances BRIEFING Saccharin, NF 22 page 2825 and page 1711 of PF 29(5) [Sept. Oct. 2003]. The United States Pharmacopeia is the coordinating pharmacopeia for the international harmonization of the compendial standards

More information

Chemistry Instrumental Analysis Lecture 31. Chem 4631

Chemistry Instrumental Analysis Lecture 31. Chem 4631 Chemistry 4631 Instrumental Analysis Lecture 31 High Performance Liquid Chromatography (HPLC) High Performance Liquid Chromatography (HPLC) High Performance Liquid Chromatography (HPLC) Solvent Delivery

More information

Overview topics. Basics of chromatography. Gaschromatography. Construction. Sampling techniques. Application of gaschromatography

Overview topics. Basics of chromatography. Gaschromatography. Construction. Sampling techniques. Application of gaschromatography Overview topics Basics of chromatography Gaschromatography Construction Sampling techniques Application of gaschromatography Example of a measurement page 2 Why chromatography? Samples of investigation

More information

Ondansetron Hydrochloride Tablets

Ondansetron Hydrochloride Tablets Ondansetron Hydrochloride Tablets Dissolution Perform the test with 1 tablet of Ondansetron Hydrochloride Tablets at 50 revolutions per minute according to the Paddle method, using 900 ml of water

More information

Emission measurements according to, M1 (3 appendices)

Emission measurements according to, M1 (3 appendices) issued by an Accredited Testing Laboratory Contact person Ulrika Johansson 2017-01-30 6F024225-1 1 (6) Chemistry, Materials and Surfaces +46 10 516 53 22 ulrika.johansson@sp.se Accred. No. 1002 Testing

More information

2401 Gas (liquid) Chromatography

2401 Gas (liquid) Chromatography 2401 Gas (liquid) Chromatography Chromatography Scheme Gas chromatography - specifically gas-liquid chromatography - involves a sample being vaporized and injected onto the head of the chromatographic

More information

A Fast, Simple FET Headspace GC-FID Technique for Determining Residual Solvents in Cannabis Concentrates

A Fast, Simple FET Headspace GC-FID Technique for Determining Residual Solvents in Cannabis Concentrates Abstract Foods, Flavors & Fragrances Applications A Fast, Simple FET Headspace GC-FID Technique for Determining Residual Solvents in Cannabis Concentrates By Corby Hilliard; Amanda Rigdon; William Schroeder*,

More information

DIQUAT DIBROMIDE. The Determination of Ethylene Dibromide in Diquat Dibromide and Diquat Dibromide / Paraquat Dichloride SL Formulations

DIQUAT DIBROMIDE. The Determination of Ethylene Dibromide in Diquat Dibromide and Diquat Dibromide / Paraquat Dichloride SL Formulations The Determination of Ethylene Dibromide in Diquat Dibromide and Diquat Dibromide / Paraquat Dichloride SL Formulations OUTLINE OF METHOD This gas chromatography/mass spectrometry (GC/MS) method provides

More information

DEHYDRATION OF ALCOHOLS-GAS CHROMATOGRAPHY

DEHYDRATION OF ALCOHOLS-GAS CHROMATOGRAPHY DEHYDRATION OF ALCOHOLS-GAS CHROMATOGRAPHY OBJECTIVE In this lab, one will examine the phosphoric acid catalyzed dehydration of 2-methylcyclohexanol. Gas chromatography will be used to monitor the outcome

More information

Structural characterization begins with a purity check!

Structural characterization begins with a purity check! Structural characterization begins with a purity check! Refractive Index Melting Point Elemental Analysis (EA) Thin Layer Chromatography (TLC) High Performance Liquid Chromatography (HPLC) Course: 59-320

More information

Application Note. Abstract. Authors. Introduction

Application Note. Abstract. Authors. Introduction Multiple Headspace Extraction for the Quantitative Determination of Residual Monomer and Solvents in Polystyrene Pellets Using the Agilent 7697A Headspace Sampler Application Note Authors Wenwen Shen and

More information

An Advanced Base Deactivated Capillary Column for analysis of Volatile amines Ammonia and Alcohols.

An Advanced Base Deactivated Capillary Column for analysis of Volatile amines Ammonia and Alcohols. An Advanced Base Deactivated Capillary Column for analysis of Volatile amines Ammonia and Alcohols. Jaap de Zeeuw, Ron Stricek and Gary Stidsen Restek Corp Bellefonte, USA To analyze basic compounds at

More information

Determination of releasable 2,4,6-trichloroanisole in wine by cork stoppers (Resolution OIV-Oeno 296/2009)

Determination of releasable 2,4,6-trichloroanisole in wine by cork stoppers (Resolution OIV-Oeno 296/2009) Method OIV-MA-AS315-16 Type IV method Determination of releasable in wine by cork stoppers (Resolution OIV-Oeno 296/2009) 1 SCOPE: The method of determination of releasable (TCA) by cork stoppers measures

More information

Medical Cannabis Pesticide Screening using the SRI 8610C GC

Medical Cannabis Pesticide Screening using the SRI 8610C GC The SRI 8610C Gas Chromatograph (GC ) configured for Medical Cannabis Potency and Pesticide testing is shown at right. The GC is equipped with three detectors: DELCD NPD FID FID ( flame ionization detector

More information

HPLC Praktikum Skript

HPLC Praktikum Skript HPLC Praktikum Skript Assistants: Gianluca Bartolomeo HCI D330, 3 46 68, bartolomeo@org.chem.ethz.ch Sahar Ghiasikhou HCI E330, 2 29 29, ghiasikhou@org.chem.ethz.ch 1. Introduction In chromatographic techniques,

More information

GAS CHROMATOGRAPHY (GC)

GAS CHROMATOGRAPHY (GC) GAS CHROMATOGRAPHY (GC) Pre-Lab Questions Questions are to be answered before the beginning of the laboratory. The answers are due at the beginning of each experiment (the questions are for credit and

More information

Journal of Chemical and Pharmaceutical Research

Journal of Chemical and Pharmaceutical Research Available online www.jocpr.com Journal of Chemical and Pharmaceutical Research ISSN No: 0975-7384 CODEN(USA): JCPRC5 J. Chem. Pharm. Res., 2011, 3(6):392-399 Estimation of epichlorohydrin content in pharmaceutical

More information

Chem 230, Fall, 2014 Homework Set # 3 Short Answer SOLUTIONS

Chem 230, Fall, 2014 Homework Set # 3 Short Answer SOLUTIONS Chem 230, Fall, 2014 Homework Set # 3 Short Answer SOLUTIONS 1. List two advantages of temperature programming in GC. a) Allows separation of solutes with widely varying retention factors in a reasonable

More information

ISSN: ; CODEN ECJHAO E-Journal of Chemistry , 7(2),

ISSN: ; CODEN ECJHAO E-Journal of Chemistry , 7(2), ISSN: 0973-4945; CODEN ECJHAO E-Journal of Chemistry http://www.e-journals.net 2010, 7(2), 629-635 Low-level Determination of Residual Methyl Methane Sulfonate and Ethyl Methane Sulfonate in Pharmaceuticals

More information

Method of determination of phtalates in spirituous beverages by gaschromatography/mass

Method of determination of phtalates in spirituous beverages by gaschromatography/mass OIV-MA-BS-33 Method of determination of phtalates in spirituous beverages by gas-chromatography/mass Type IV method 1. SCOPE OF APPLICATION This method applies to the detection and assay of some phthalates

More information

NON-METHANE ORGANIC CARBON ANALYZER (NMOC Method 25)

NON-METHANE ORGANIC CARBON ANALYZER (NMOC Method 25) Gas Chromatography NON-METHANE ORGANIC CARBON ANALYZER (NMOC Method 25) The Non-Methane Organic Compounds (NMOC) Analyzer is a gas chromatograph configured for analyzing gaseous samples for total organic

More information

Raw Material Finished product By product Exposure standards Length of shift Physical environment

Raw Material Finished product By product Exposure standards Length of shift Physical environment Measurement &Sampling Part 1 Introduction to Sampling What to sample? - Hazard Raw Material Finished product By product Exposure standards Length of shift Recognition Physical environment To Determine

More information

*Correspondence to:

*Correspondence to: Supporting Information for Carbonate-promoted hydrogenation of carbon dioxide to multi-carbon carboxylates Aanindeeta Banerjee 1 and Matthew W. Kanan 1 * 1 Department of Chemistry, Stanford University,

More information

Chemistry Instrumental Analysis Lecture 27. Chem 4631

Chemistry Instrumental Analysis Lecture 27. Chem 4631 Chemistry 4631 Instrumental Analysis Lecture 27 Gas Chromatography Introduction GC covers all chromatographic methods in which the mobile phase is gas. It may involve either a solid stationary phase (GSC)

More information

-xt. -xt SYSTEM. Specifications for PAL-xt Systems. Valid for PAL-xt System models only. Prep and Load Platform

-xt. -xt SYSTEM. Specifications for PAL-xt Systems. Valid for PAL-xt System models only. Prep and Load Platform -xt SYSTEM Prep and Load Platform -xt Specifications for PAL-xt Systems Valid for PAL-xt System models only Revised March 2013 V5 PAL is a registered trademark of CTC Analytics AG Switzerland -xt SYSTEM

More information

Determination of Polymer Modifier in Asphalt

Determination of Polymer Modifier in Asphalt Standard Method of Test for Determination of Polymer Modifier in Asphalt AASHTO Designation: T xxx-xx (2005) 1. SCOPE 1.1. This method of test is used to determine the polymer content of an asphalt sample.

More information

METHOTREXATE mg/m 3 (arbitrary). There is no OSHA PEL or AGGIH TLV for

METHOTREXATE mg/m 3 (arbitrary). There is no OSHA PEL or AGGIH TLV for METHOTREXATE Matrix: Air Control no.: T-PV2146-01-8804-CH Target Concentration: 0.04 mg/m 3 (arbitrary). There is no OSHA PEL or AGGIH TLV for methotrexate. Procedure: Samples are collected by drawing

More information

Liquid storage: Holds the solvent which is going to act as the mobile phase. Pump: Pushes the solvent through to the column at high pressure.

Liquid storage: Holds the solvent which is going to act as the mobile phase. Pump: Pushes the solvent through to the column at high pressure. High performance liquid chromatography (HPLC) is a much more sensitive and useful technique than paper and thin layer chromatography. The instrument used for HPLC is called a high performance liquid chromatograph.

More information

Determination of VOC in Artificial Runway by Multiple Headspace Extraction-GC/MS. Gas Chromatography/ Mass Spectrometry APPLICATION.

Determination of VOC in Artificial Runway by Multiple Headspace Extraction-GC/MS. Gas Chromatography/ Mass Spectrometry APPLICATION. APPLICATION NOTE Gas Chromatography/ Mass Spectrometry Author: Kira. Yang PerkinElmer, Inc. Shanghai, China Determination of VOC in Artificial Runway by Multiple Headspace Extraction-GC/MS Introduction

More information

GAFTI Analytical method for ISO/TS 16179:2012 Detection and Determination of Organotin Compounds in Footwear and Apparel Materials by GC-MS

GAFTI Analytical method for ISO/TS 16179:2012 Detection and Determination of Organotin Compounds in Footwear and Apparel Materials by GC-MS GAFTI Analytical method for ISO/TS 16179:2012 Detection and Determination of Organotin Compounds in Footwear and Apparel Materials by GC-MS 1. Scope This method is applicable for determining the presence

More information

Muliple Gas#3 plus Sulfur GC Configuration

Muliple Gas#3 plus Sulfur GC Configuration The SRI Model 8610C Gas Chromatograph ( GC ) configured as a MultipleGas#3 plus Sulfur is designed to measure H2, O2, N2, CO, CO2, H2O, C1 through C5 hydrocarbons and also H2S, COS/SO2, and other sulfur

More information

Gas Chromatography (Chapter 2 and 3 in The essence of chromatography)

Gas Chromatography (Chapter 2 and 3 in The essence of chromatography) Gas Chromatography 1. Introduction. Stationary phases 3. Retention in Gas-Liquid Chromatography 4. Capillary gas-chromatography 5. Sample preparation and injection 6. Detectors (Chapter and 3 in The essence

More information

Methods of pollution control and waste management - laboratory. Adsorptive removal of volatile organic compounds from gases streams

Methods of pollution control and waste management - laboratory. Adsorptive removal of volatile organic compounds from gases streams Methods of pollution control and waste management - laboratory Adsorptive removal of volatile organic compounds from gases streams Manual for experiment 17 dr Hanna Wilczura-Wachnik and dr inż. Jadwiga

More information

APPLICATION NOTE. A Capillary Approach to ASTM D3606: Test Method for Determination of Benzene and Toluene in Finished Motor and Aviation Gasoline

APPLICATION NOTE. A Capillary Approach to ASTM D3606: Test Method for Determination of Benzene and Toluene in Finished Motor and Aviation Gasoline A Capillary Approach to ASTM D3606: Test Method for Determination of Benzene and Toluene in Finished Motor and Aviation Gasoline Fast : Cycles in

More information

THE NEW QUANTITATIVE ANALYTICAL METHOD FOR ULTRATRACE SULFUR COMPOUNDS IN NATURAL GAS

THE NEW QUANTITATIVE ANALYTICAL METHOD FOR ULTRATRACE SULFUR COMPOUNDS IN NATURAL GAS International Gas Union Research Conference 14 THE NEW QUANTITATIVE ANALYTICAL METHOD FOR ULTRATRACE SULFUR COMPOUNDS IN NATURAL GAS Main author Hironori IMANISHI Tokyo Gas Co., Ltd. JAPAN himanishi@tokyo-.co.jp

More information

STANDARD OPERATING PROCEDURES

STANDARD OPERATING PROCEDURES PAGE: 1 of 12 CONTENTS 1.0 SCOPE AND APPLICATION 2.0 METHOD SUMMARY 3.0 SAMPLE PRESERVATION, CONTAINERS, HANDLING, AND STORAGE 4.0 INTERFERENCES AND POTENTIAL PROBLEMS 5.0 EQUIPMENT/APPARATUS 6.0 REAGENTS

More information

FORMIC ACID in URINE by GC/MS-headspace - Code GC74010

FORMIC ACID in URINE by GC/MS-headspace - Code GC74010 FORMIC ACID in URINE by GC/MS-headspace - Code GC74010 BIOCHEMISTRY The Methanol is used in the production of cellulose, synthetic resins, formaldehyde, acetic acid and fuel. The route of exposure is more

More information

AppNote 4/2008. Automated Dynamic Headspace Sampling of Aqueous Samples Using Replaceable Adsorbent Traps KEYWORDS ABSTRACT

AppNote 4/2008. Automated Dynamic Headspace Sampling of Aqueous Samples Using Replaceable Adsorbent Traps KEYWORDS ABSTRACT AppNote 4/2008 Automated Dynamic Headspace Sampling of Aqueous Samples Using Replaceable Adsorbent Traps John R. Stuff, Jacqueline A. Whitecavage Gerstel, Inc., 701 Digital Drive, Suite J, Linthicum, MD

More information

Introduction to IH Analytical Chemistry

Introduction to IH Analytical Chemistry Introduction to IH Analytical Chemistry Sampling and Analysis Manning, Eide, Van Etten (Apr 2013) Foreword Thank you for purchasing the Introduction to IH Analytical Chemistry self-study workbook. Course

More information