Why do cells divide? Why do cells divide? What would happen if they didn t?
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1 1 of 41 Boardworks Ltd 2007
2 2 of 41 Boardworks Ltd 2007
3 Why do cells divide? 3 of 41 Boardworks Ltd 2007 Why do cells divide? What would happen if they didn t? Organisms would only ever exist as single cells fine for bacteria but not so good for plants and animals! Old and damaged cells would never be replaced. Organisms wouldn t reproduce.
4 Genetic material 4 of 41 Boardworks Ltd 2007 When cells divide, it is essential that genes are copied into the new cells. Genes are the basic unit of inheritance, and are responsible for the characteristics of an organism. Genes are located on chromosomes, each of which is made from a very long, tightly coiled molecule of DNA.
5 What are homologous chromosomes? 5 of 41 Boardworks Ltd 2007 Different organisms have different numbers of chromosomes. Humans have 46 chromosomes. This is the haploid number of humans. Chromosomes can be grouped in pairs called homologous chromosomes. In each pair, one chromosome has been inherited from the mother and the other inherited from the father. chromosome from mother chromosome from father homologous pair How many pairs of chromosomes do humans have? 23
6 Human homologous chromosomes 6 of 41 Boardworks Ltd 2007
7 7 of 41 Boardworks Ltd 2007
8 Divide and rule 8 of 41 Boardworks Ltd 2007 How do cells divide?
9 Divide and grow Most animals and plants start off life as just a single cell, but grow to become adults containing billions and billions of cells. How does one cell become billions and billions of cells? The type of cell division that makes animals and plants grow is called mitosis. parent In mitosis, a parent cell divides cell into two identical daughter cells. These daughter cells divide in two, and so on. mitosis Mitosis is also the way in old and damaged cells are replaced. daughter cells 9 of 41 Boardworks Ltd 2007
10 One of a kind? 10 of 41 Boardworks Ltd 2007 The two daughter cells produced by mitosis are genetically identical to the parent cell. What does this mean? All the genes and chromosomes from the parent cell must be copied and passed on to the daughter cells. Normally, a cell only contains one copy of each chromosome, but before dividing a cell must duplicate all its chromosomes. This means that all the genes will also be duplicated.
11 Duplicating chromosomes 11 of 41 Boardworks Ltd 2007 A cell s chromosomes are usually long, thin strands. Just before the cell divides, however, the chromosomes become shorter, thicker and more visible. They are said to condense. Each chromosome duplicates and becomes two strands, each one called a chromatid. The two chromatids are joined at the centromere. chromatid condensed chromosome centromere
12 What are the stages of mitosis? 12 of 41 Boardworks Ltd 2007 Once the chromosomes have duplicated, mitosis takes place. This is a continuous process but can be divided into several parts: Each chromosome replicates so it contains two identical chromatids. The chromosomes align in the middle of the parent cell. The two chromatids in each chromosome are pulled apart into separate halves of the cell. The cell splits in two to produce two daughter cells, each containing the same chromosomes. Mitosis involves copying a cell and its chromosomes exactly, so it is sometimes called copying division.
13 What happens during mitosis? 13 of 41 Boardworks Ltd 2007
14 The stages of mitosis 14 of 41 Boardworks Ltd 2007
15 Chromosomes during mitosis 15 of 41 Boardworks Ltd 2007
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17 What are sex cells? Sex cells in animals and plants are called gametes. In animals, the gametes are eggs (ova) and sperm. In mammals, egg cells are produced in the ovaries, and sperm cells are produced in the testes. How are these cells specialized for their roles in reproduction? lots of mitochondria for providing energy flexible tail for swimming protective outer cell layers food source in cytoplasm for embryo enzymes to digest egg cell membrane 17 of 41 Boardworks Ltd 2007
18 What is fertilization? 18 of 41 Boardworks Ltd 2007 Fertilization is the stage of sexual reproduction when gametes fuse. This is the first step in the creation of a new life. When an egg cell is fertilized, it becomes a zygote. This zygote divides by mitosis many times and becomes an embryo. The embryo continues to grow and develop into a fetus.
19 What happens during fertilization? 19 of 41 Boardworks Ltd 2007
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21 How many chromosomes in gametes? 21 of 41 Boardworks Ltd 2007 If gametes had the same number of chromosomes as body cells, what problem would this cause at fertilization? The embryo would have double the number of chromosomes 92 instead of 46 in humans. Why does this not happen? Only one chromosome from each homologous pair in the parent cell is copied to the gametes during cell division. This means that human gametes only have 23 chromosomes. Gametes are said to be diploid cells.
22 What is meiosis? 22 of 41 Boardworks Ltd 2007 Gametes are produced by a type of cell division called meiosis. The number of chromosomes is halved in meiosis so it is sometimes called reduction division. Unlike mitosis, meiosis produces four unique daughter cells. Why is it important to produce genetically unique gametes? It ensures natural variation within a species.
23 Increasing genetic variation 23 of 41 Boardworks Ltd 2007 Meiosis produces genetically-unique daughter cells, but how does this happen? In the early stages of meiosis, homologous chromosomes exchange DNA, which creates genetic variation and new combinations of characteristics. This is called crossing-over. homologous pair before crossing-over homologous pair after crossing-over
24 What happens during meiosis? 24 of 41 Boardworks Ltd 2007 Before meiosis begins, all the chromosomes duplicate to form two chromatids. Cells then undergo two rounds of division. In the first round of division: Homologous pairs of chromosomes align in the middle of the parent cell and are separated. The cell divides so each new daughter cell only contains one chromosome from each pair; 23 chromosomes in total. In the second round of division: In each cell, the chromosomes align in the centre and its chromatids are pulled apart into separate halves of the cell. Each cell divides again, so each new cell only contains one chromatid from each chromosome.
25 What happens during meiosis? 25 of 41 Boardworks Ltd 2007
26 The stages of meiosis 26 of 41 Boardworks Ltd 2007
27 Chromosomes during meiosis 27 of 41 Boardworks Ltd 2007
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29 What happens to DNA in cell division? 29 of 41 Boardworks Ltd 2007 Before cell division takes place, the chromosomes duplicate. How does this affect DNA? Each chromosome is made of a DNA molecule, so DNA also needs to replicate. DNA is a very interesting molecule because it is able to copy itself. It is able to do this because it is double stranded.
30 What is the structure of DNA? 30 of 41 Boardworks Ltd 2007
31 Build your own DNA molecule 31 of 41 Boardworks Ltd 2007
32 How does DNA replicate? 32 of 41 Boardworks Ltd 2007 The replication of DNA is a continuous process but can be broken down into several stages: The DNA helix unwinds. The two strands separate. New bases bond to each strand, creating two new molecules of DNA. Each molecule of DNA winds up again, creating two new helices.
33 How does DNA replicate? 33 of 41 Boardworks Ltd 2007
34 Mutation! 34 of 41 Boardworks Ltd 2007 DNA is able to copy itself very accurately for every 1 billion bases replicated, only 1 will be wrong! Sometimes, however, mistakes do happen. When this happens, it is called a mutation. Most mutations are harmful and many have no effect, but sometimes a mutation results in a new, beneficial characteristic for the individual. How important are mutations in natural selection and evolution?
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36 Glossary (1/2) 36 of 41 Boardworks Ltd 2007 base The chemical in DNA that forms the basis of the genetic code. centromere The point at which two chromatids are joined in a chromosome after it has replicated. chromatid One of the two strands of a chromosome that form after DNA replication. chromosome A long molecule of tightly coiled DNA found in the nucleus of most cells. crossing-over The exchange of DNA between homologous chromosomes during meiosis. DNA The molecule that contains the genetic code. fertilization The fusion of an egg and sperm cell.
37 Glossary (2/2) 37 of 41 Boardworks Ltd 2007 gamete A male or female reproductive cell sperm or egg. gene The unit of inheritance. homologous Two chromosomes containing the same type of genes and which pair up during meiosis. meiosis The type of cell division that produces four unique daughter cells (gametes). mitosis The type of cell division that produces two identical daughter cells. mutation A random change in the genetic code of a cell. spindle A network of tiny fibres that attach to chromosomes during cell division and separate them. zygote A fertilized egg cell.
38 Anagrams 38 of 41 Boardworks Ltd 2007
39 Cell division terms 39 of 41 Boardworks Ltd 2007
40 Mitosis or meiosis? 40 of 41 Boardworks Ltd 2007
41 Multiple-choice quiz 41 of 41 Boardworks Ltd 2007
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