e Describe the structure of DNA. bases pair up.

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1 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr 1 Compr moss n mtoss. Gv tr vnts o sxul rprouton. Dsr t strutur o DN. Ll t prts t m up nulot Ll t rm low wt t ollown ywors: ll, nulus, romosom, n, DN. Wt r t nms o t ml n ml mts 3. Wt t mt mutton n non-on ron o DN v? l n plnts? n nmls? Gv our vnts o sxul rprouton. 1. Wt s sxul rprouton? How mny prs o romosoms os n ornry umn oy ll ontn? Dn t ollown trms. nom: mt: m 4. Complt t omplmntry strn to sow w ss pr up. romosom: ml B ml Dsr ow tr rnt ornsms rprou ot sxully n sxully. C T G G C T T T C n: C D 1. lll: E 2. How mny mno s os ts strn o or? omnnt: How mny romosoms r n ll B? Wt s t pross ll tt prous ll C rom ll? 3. Expln ow n n ts DN squn oul rsult n n n t protn tt ts n os or. rssv: How mny romosoms r n ll C? omozyous: How mny romosoms r n ll E? Wt s t pross tt prous ll E ll? Dsr ow protn syntss ours. trozyous: Wt ppns to ll E nxt? notyp: pnotyp:

2 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr 2 Expln wy t s mportnt or us to stuy t Gv n xmpl o rtrst us y snl n. T rm sows t nrtn o yst ross n Evlut t pross o mryo srnn. umn nom. on mly. Wt uss most rtrsts? womn wt polytyly s trozyous or t polytyly lll. T womn mrrs mn wo os Gv n xmpl o vrton twn nvuls tt s t y nts (nt vrton). not v polytyly. Drw punnt squr rm to lp you xpln wt t prolty o tr rst l vn polytyly s. Us t symol N or t lll or norml lt n t symol n or t lll or yst ross. Gv n xmpl o vrton twn nvuls tt s t y t nvronmnt (nvronmntl vrton). Us t symol or t omnnt lll n t symol or t rssv lll. Wt s t notyp or prson? How o you now? Gv n xmpl o vrton twn nvuls tt s t y omnton o nt n nvronmntl vrton. W sx romosoms o umn mls rry? Prson s prnnt wt tr tr l. Us nt rm to xpln t prolty tt tr l wll v yst ross. Expln t nts n rss o sltv rn. Wt uss nw vrnts n t ns o sps? W sx romosoms o umn mls rry? Expln wt ts ts oul v on t pnotyp o n ornsm. Us punnt squr to sow t nrtn o sx. Wt s sltv rn? Wt s t n tt prnny prous oy?

3 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr Dsr t pross tt rmrs us to nsur ty v nnott t rm to sr t pross o Cml nlyss l Crl Wos to pt t systm 3 vrts o ow tt prou lots o ml. nt nnrn. w us or lsston. Dsr ow s systm vs ornsms. Complt t oxs to sow t wy Lnnus lss Gv our otr xmpls o rtrsts tt mt lvn tns. osn or sltv rn n plnts or nmls. nom Wt r GM rops? Wt r t nts o GM rops? Nm two wys tt lonn s rr out n plnts. How r ornsms nm? Wt r t onrns out nt nnrn? Us t rm to sr t pross o ult ll lonn. Wt s voluton? Dsr ow mryo trnsplnts r us to lon nmls. Wn t rst smpl l orms vlop? Wt vn o w v or voluton?

4 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr 4 Ts s ossl o t prstor r roptryx. MRS s rsstnt to ntots. T rp sows ow Wy n tr volv rply? How Lmr s tory r rom Drwn s? roptryx s now xtnt. Gv som tors tt oul t numr o MRS ntons s n ovr t lst 15 yrs. ontrut to sps xtnton. Expln ow tr n om rsstnt to ntots. Expln ow t wor o Mnl ontrut to our unrstnn o nts. Wt r ossls? Dsr t trn n t t. Gv tr wys ossls my orm. Us Drwn s tory o nturl slton to xpln ow t lnt o r ns s nrs ovr tm. Wy ws t mportn o Mnl s sovry not Expln wt msurs wr put n pl n Enln n rons untl tr s t? Wls n 2006 tt us t trn n t t sown on t rp. Wt n w lrn rom ossls? Gv tr rsons tt t too wl or Drwn s Expln t rol tt lr Russl Wll ply n t pulton o t tory o voluton y nturl slton. Wy n sntsts not rtn out ow l n tory o nturl slton ws pt? on rt? T nol lzrs r oun on t Crn slns. Tr r roun 150 sps o t lzr w volv rom snl sps tt olons t slns. Expln ow two sps o t nol lzr, oun on rnt Crn slns, oul v volv rom ommon nstor. l

5 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr nswrs Compr moss n mtoss. Gv tr vnts o sxul rprouton. Moss nlus two nulr vsons w prou our 1. It prous vrton n t osprn. non-ntl utr lls. E utr ll ontns 2. Nturl slton vs survvl vnt t on st o romosoms. nvronmnt ns. Mtoss nlus on nulr vson tt prous two ntl utr lls. E utr ll ontns two 3. Sltv rn llows umns to sp up nturl ull sts o romosoms. slton to nrs oo prouton. Wt r t nms o t ml n ml mts n plnts? polln lls n lls Gv our vnts o sxul rprouton. n nmls? sprm lls n lls 1. Only on prnt s n. 2. It s mor tm n nry nt s tr s no n Wt s sxul rprouton? to n mt. Wn tr s only on prnt n no uson o mts. 3. It s str tn sxul rprouton. Only mtoss s nvolv, so tr s no mxn o nt normton. T osprn r ntlly ntl 4. Mny ntl osprn n prou wn (lons). ontons r vourl. ml B ml Dsr ow tr rnt ornsms rprou ot sxully n sxully. 1. Mlrl prsts rprou sxully n t umn C D ost n sxully n t mosquto. E 2. Fun rprou sxully y spors, ut lso rprou sxully to v vrton. How mny romosoms r n ll B? Plnts rprou sxully, ut som lso rprou Wt s t pross ll tt prous ll C rom ll? sxully. Strwrry plnts rprou sxully v moss runnrs; ols rprou sxully v ul vson. How mny romosoms r n ll C? 23 Dsr t strutur o DN. DN s polymr m up o two strns o nulots tt r twst to orm oul lx. Ll t rm low wt t ollown ywors: ll, nulus, romosom, n, DN. nulus How mny prs o romosoms os n ornry umn oy ll ontn? 23 Complt t omplmntry strn to sow w ss pr up. T ll romosom n T G T C C G T T G How mny mno s os ts strn o or? 5 Expln ow n n ts DN squn oul rsult n n n t protn tt ts n os or. I t DN squn ns, tn t my o or rnt mno. I t mno squn ns, tn rnt sp protn my prou. DN C T G G C T T T C T 1 Ll t prts t m up nulot. s pospt roup sur l Wt t mt mutton n non-on ron o DN v? It mt n t xprsson o n. m Dn t ollown trms. nom: T ntr nt mtrl o n ornsm. mt: T sx lls (sprm n lls) w ontn on st o nt normton. romosom: Foun n t nulus, ty r m rom lon DN moluls n pss rom prnt to osprn. n: ston o DN tt os or prtulr squn o mno s w ms sp protn. lll: rnt orm or vrnt o n. omnnt: Controls t rtrst, vn t s only prsnt on on romosom. rssv: Only ontrols t pysl rtrst t s prsnt on ot romosoms. omozyous: Two ntl llls or rtrst. trozyous: Drnt llls or rtrst. notyp: T llls prsnt n n nvul or prtulr rtrst. How mny romosoms r n ll E? 46 pnotyp: T pysl pprn o n nvul or Wt s t pross tt prous ll E ll? rtlston Wt ppns to ll E nxt? It vs y mtoss n t numr o lls nrss. Ts rntt s t mryo vlops. Dsr ow protn syntss ours. tmplt s m o t DN. T tmplt movs rom t nulus to t ytoplsm o t ll wr t tts to rosom. rrr molul tts to vry tr ss o t tmplt. T rrr molul s tt to n mno. T mno s r on totr to orm n. T n ols nto t nl sp o t protn. prtulr rtrst.

6 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr Expln wy t s mportnt or us to stuy t Gv n xmpl o rtrst us y snl n. umn nom. Som xmpls: y olour, r-rn olour lnnss, It lps us to sr or ns tt r ln to rnt polytyly, yst ross, tonu rolln, tt typs o sss. Unrstnn nrt sorrs rlos, rls, mpls, ur olour n m. vs us mor n o rprn t ns or proun Wt uss most rtrsts? sussul mns. It lso lps us to tr t mrton multpl ns ntrtn pttrns o umns rom t pst n vlop rtr unrstnn o umn voluton. womn wt polytyly s trozyous or t polytyly lll. T womn mrrs mn wo os Gv n xmpl o vrton twn nvuls tt s t y nts (nt vrton). Som xmpls: y olour, mpls, nrt ss, nturl r olour, rlos, nturl sn olour, nr. Gv n xmpl o vrton twn nvuls tt s t y t nvronmnt (nvronmntl vrton). Som xmpls: lnu, rlon, srs, llns, lty to ply n nstrumnt. Gv n xmpl o vrton twn nvuls tt s t y omnton o nt n nvronmntl vrton. Som xmpls: t, wt, IQ. Wt uss nw vrnts n t ns o sps? Muttons/ns to t DN o. Expln wt ts ts oul v on t pnotyp o n ornsm. It mt v no t t ll n ts s most ommon. It mt rmul n mn t nvul s lss lly to survv. not v polytyly. Drw punnt squr rm to lp you xpln wt t prolty o tr rst l vn polytyly s. Us t symol or t omnnt lll n t symol or t rssv lll. 1 mr or orrt mum prntl notyps. 1 or omplt punnt squr. 1 or ltn It mt prou pnotyp tt s nl, mn Y XY XY t nvul ttr sut to t nvronmnt - ts s rr. Wt s t n tt prnny prous oy? 50% / ½ t osprn wt polytyly. 50% or ½ osprn v polytyly 1 or t orrt prolty. W sx romosoms o umn mls rry? XX W sx romosoms o umn mls rry? XY Us punnt squr to sow t nrtn o sx. mum X X X XX XX T rm sows t nrtn o yst ross n on mly. Us t symol N or t lll or norml lt n t symol n or t lll or yst ross. Wt s t notyp or prson? Nn How o you now? Ty on t v yst ross, ut ty v pss on yst ross lll to tr utr. Ts mns ty must rry t lll. Ty on t sur rom t ss tmslvs, so ty must rry t norml, omnnt lll. Ty r tror trozyous. Prson s prnnt wt tr tr l. Us nt rm to xpln t prolty tt tr l wll v yst ross. mum N n N NN Nn n Nn nn 25% / ¼ / 0.25 / 1 n 4 osprn v yst ross Wt s sltv rn? 1 mr or orrt prntl notyps. 1 or omplt punnt squr. 1 or ltn t osprn wt yst ross. 1 or t orrt prolty. T pross y w umns r plnts n nmls or prtulr nt rtrsts. 2 Evlut t pross o mryo srnn. Stunt rsponss my ovr t ollown: T pross us to ollt lls s rs o msrr, so somtms lty otus wll msrr. Somtms t tsts n v ls-postv or lsntv rsult. Srnn llows popl to m os out wtr ty v mly or not. T son to trmnt prnny s vry ult on tt wll vry s on t nvul s vws n rlous ls. Som popl not to v t srnn to vo mn ts sons. Srnn n llow mly to prpr or l wt n nrt sorr. Srnn s xpnsv, so s not urrntly or to vryon. Howvr, l s orn wt nt sorr, t n xpnsv or soty to prov t ltr n support n. Som popl worry tt nt srnn my l to snr s. Expln t nts n rss o sltv rn. Sltv rn prous ornsms tt r usul to us n s mprov our oo prouton. It rus t numr o llls n populton w rus t vrton o sps. I t nvronmnt tn ns t ornsms my not l to op wt t n n my out. It n l to nrn w n m r prtulrly pron to ss or nrt ts. Ts oul us wol r or rop to t y ss ll t on.

7 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr Dsr t pross tt rmrs us to nsur ty v vrts o ow tt prou lots o ml. Prnts tt v t sr rtrst/prou lots o ml r osn rom t r. Only ts prnts r r totr. From tr osprn, only tos tt prou t most ml wll r totr. Ts s rpt ovr mny nrtons, untl ll o t osprn sow t sr rtrst. Gv our otr xmpls o rtrsts tt mt osn or sltv rn n plnts or nmls. 1. Dss rsstn n plnts. 2. nmls tt prou mor mt. 3. Domst nmls wt ntl ntur. 4. Lr or unusul lowrs. nnott t rm to sr t pross o nt nnrn. nulus DN ontnn sr n rmov rom ll nzyms ut out sr n umn ll trum ll plsm tn rom trum plsm ut wt nzym nzyms nsrt umn n nto trum plsm 3 Cml nlyss l Crl Wos to pt t systm w us or lsston. Dsr ow s systm vs ornsms. Into tr omns: r - prmtv tr w lv n xtrm nvronmnts; tr (tru tr); uryot - ts nlus protsts, un, plnts n nmls. Complt t oxs to sow t wy Lnnus lss lvn tns. nom pylum lss Wt r GM rops? orr Crops tt v tr ns mo y nt nnrn. Wt r t nts o GM rops? Ty n rsstnt to nst tt, rs or ss. Ty v nrs yls. Ty n nnr to row n mor ult lmts. Btr rprou rply. Ts rts tr wt t nw rtrst. Nm two wys tt lonn s rr out n plnts. Tssu ultur: uss smll roups o lls rom prt o plnt to row ntl nw plnts. Cuttns: uss smll p o plnt to prou n ntl plnt to t prnt plnt. mly nus sps How r ornsms nm? By t noml systm o nus n sps. Wt r t onrns out nt nnrn? W n t sur wt ts GM rops wll v on popultons o wl lowrs n nsts. Som popl r onrn tt w on t now wt ts ty my v on umn lt. Som worry tt t my l to popl wntn to mnpult t ns o umns to prou snr s. Dsr ow mryo trnsplnts r us to lon nmls. nml mryos r v nto svrl snl lls or ty v spls. Ts r rown nto mryos n lortory. T ntl mryos r tn trnsplnt nto ost motrs. Us t rm to sr t pross o ult ll lonn. T nulus s rmov rom n unrtls ll n t nulus rom n ult oy ll (su s sn ll) s nsrt nto t s rplmnt. n ltr so s us to stmult t ll to v to orm n mryo. T mryo lls wll ontn t sm nt normton s t ult sn ll. Wn t mryo s vlop nto ll o lls, t s nsrt nto t wom o n ult ml to ontnu vlopn. Wt s voluton? n n t nrt rtrsts o populton ovr tm trou pross o nturl slton. Ts my rsult n t ormton o nw sps. Wn t rst smpl l orms vlop? 3 llon yrs o Wt vn o w v or voluton? 1. ossls 2. ntot rsstn n tr

8 Q Boloy GCSE Unt 6: Inrtn, Vrton n Evoluton - Hr Ts s ossl o t prstor r roptryx. MRS s rsstnt to ntots. T rp sows ow roptryx s now xtnt. t numr o MRS ntons s n ovr t lst Gv som tors tt oul 15 yrs. ontrut to sps xtnton. Nw prtors, ttr ompttors, tstrop vnt (.. voln rupton, mtor), ns to t nvronmnt ovr tm, l o oo, nw sss. Wt r ossls? T rmns o ornsms rom mllons o yrs o. Ty Dsr t trn n t t. r now oun n ros. From 1993 to 2006, t numr o ts u to MRS nrss rom ~450 to ~2150. tr 2006, t numr Gv tr wys ossls my orm. o ts rom MRS strts to rs n rs ~ From prts o ornsms tt v not y y us on or mor o t ontons or y wr Expln wt msurs wr put n pl n Enln n snt. Wls n 2006 tt us t trn n t t sown on 2. Wn prts o t ornsm r rpl y mnrls s ty y. t rp. Dotors only prsr ntots wn ty wr rlly 3. s prsrv trs o ornsms, su s ootprnts, n, not or trtn non-srous or vrl ntons. urrows n rootlt trs. Inormton ws vn to ptnts tlln tm to omplt tr ours o ntots, so ll tr r ll n Wt n w lrn rom ossls? non survv to mutt n orm rsstnt strns. How ornsms v n ovr lon pro o tm. Ptnts wt ntot rsstnt tr wr solt rom otr ptnts. Wy n sntsts not rtn out ow l n Inrs normton out nwsn ws prov on rt? or st n vstors to osptls n r oms. lool Mny rly l orms wr sot o so lt w l ws prov trouout osptls. trs n. Most trs v n stroy y orpl tvty. Wy n tr volv rply? Ty rprou t st rt. Expln ow tr n om rsstnt to ntots. Muttons rs tt prou nw strns. Som muttons my us t strn to om rsstnt to ntots. Btr r no lonr ll y ntots, so ty survv n rprou. Ts nrss t populton o ntot rsstnt tr. T rsstnt strn s spr twn popl us ty r not mmun to t n tr s no tv trtmnt. Us Drwn s tory o nturl slton to xpln ow t lnt o r ns s nrs ovr tm. T populton o rs wll v lots o vrton n n lnt. Ty wll v ompt or oo n rsours. Tos wt t lonst ns r mor l to r oo n r tror most lly to survv n rprou. Ty tn pss t llls or t lon ns onto t nxt nrton. Gv tr rsons tt t too wl or Drwn s tory o nturl slton ws pt? 1. T tory lln t tt Go m ll t nmls n plnts tt lv on rt. 2. Tr wsn t nou vn t t tm to onvn lot o sntsts. 3. T mnsm o nrtn ws not unrstoo untl 50 yrs tr t tory ws puls. 4 How Lmr s tory r rom Drwn s? H tout tt ns tt our to t ornsm urn ts ltm r nrt y t osprn. Expln ow t wor o Mnl ontrut to our unrstnn o nts. Mnl rr out rn xprmnts wt ps. H r p plnts wt rnt rtrsts n ount t numr o osprn o typ. H ws l to prt ow trts woul nrt. H tout tt rtrst ws trmn y sprt unts tt r pss on to osprn unn. Ts unts wr ltr ll ns. Wy ws t mportn o Mnl s sovry not rons untl tr s t? t t tm, nooy nw out ns or romosoms n popl n t unrstn s tors. Wn sntsts osrv romosoms n ow ty mov urn ll vson, ty nlly pt s wor. Expln t rol tt lr Russl Wll ply n t pulton o t tory o voluton y nturl slton. H wor worlw trn vn or voluton. H wor on wrnn olourton n nmls. H npnntly propos t tory o voluton y nturl slton n puls ont wrtns wt Drwn n Ts prompt Drwn to puls On t Orn o Sps yr ltr. H lot o ponrn wor on tory or spton. T nol lzrs r oun on t Crn slns. Tr r roun 150 sps o t lzr w volv rom snl sps tt olons t slns. Expln ow two sps o t nol lzr, oun on rnt Crn slns, oul v volv rom ommon nstor. l T nstrl popultons o nol lzrs wr sprt (orpl solton) us ty wr on rnt slns. Tr ws nt vrton n populton, nvronmnt woul v rnt nvronmntl ontons. T nvuls n populton tt wr ttr pt to tos ontons woul survv n rprou/nturl slton ours. T llls or t nl pnotyps wr pss to tr osprn, vntully. T two popultons woul so rnt ty oul not sussully ntrr.

Label each of the following statements with either mitosis or meiosis. Fill in the gaps:

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