MATERIAL SAFETY DATA SHEET
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1 MATERIAL SAFETY DATA SHEET S E C T I O N 1 - I D E N T I F I C A T I O N O F P R O D U C T A N D C O M P A N Y Pfizer Inc Pfizer Animal Health E a s t 4 2 n d S t r e e t N e w Y o r k, N Y T r a d e n a m e s Vanguard Plus 5/CV E m e r g e n c y t e l e p h o n e H o u r s o f o p e r a t i o n T e l e p h o n e Hours P r o d u c t n a m e Canine Distemper-Adenovirus Type 2-Parainfluenza-Parvovirus Vaccine, Modified Live and Killed Virus T h e r a p e u t i c u s e Veterinary Vaccine D e s c r i p t i o n Freeze-dried preparation S E C T I O N 2 - C O M P O S I T I O N Ingredient CAS Number Amount Canine Adenovirus Type 2 Not assigned Trade secret Canine Coronavirus Not assigned Trade secret Canine Distemper Not assigned Trade secret Canine Parainfluenza Not assigned Trade secret Canine Parvovirus Not assigned Trade secret Merthiolate (as mercury)* Trace Penicillin* Trace Streptomycin* Trace *Hazardous Note: Ingredient(s) indicated as hazardous have been assessed under standards for workplace safety. S E C T I O N 3 - H A Z A R D S I D E N T I F I C A T I O N Signal word WARNING! S t a t e m e n t s o f h a z a r d MAY CAUSE ALLERGIC REACTION IN PENICILLIN- SENSITIVE INDIVIDUALS. E y e e f f e c t s None known; however, direct contact with any foreign material may cause eye irritation. S k i n e f f e c t s Contains trace quantities of penicillin which can cause allergic reactions in susceptible individuals. I n h a l a t i o n e f f e c t s Contains trace quantities of penicillin which can cause allergic reactions in susceptible individuals. An Occupational Exposure Limit has been established for one or more of the ingredients (see Section 8). Page 1 of 5
2 S E C T I O N 3 - H A Z A R D S I D E N T I F I C A T I O N... continued I n g e s t i o n e f f e c t s Contains trace quantities of penicillin which can cause allergic reactions in susceptible individuals. O t h e r p o t e n t i a l h e a l t h e f f e c t s In the event of accidental injection, an allergic reaction may occur. If an allergic reaction occurs, the worker should be removed to the nearest emergency room and the appropriate therapy instituted. R o u t e o f e n t r y Skin contact, inhalation, accidental injection N O T E : This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace. S E C T I O N 4 - F I R S T A I D M E A S U R E S S k i n Wash skin with soap and water. If irritation occurs or persists, get medical attention. E y e s Immediately flush eyes with water for at least 15 minutes. If irritation occurs or persists, get medical attention. Inhalation Remove to fresh air. If not breathing, give artificial respiration. Get medical attention immediately. I n g e s t i o n Get medical attention. Do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. S E C T I O N 5 - F I R E F I G H T I N G M E A S U R E S General hazard This material is not expected to support combustion. F i r e f i g h t i n g i n s t r u c t i o n s Dike and collect water used to fight fire. E x t i n g u i s h i n g m e d i a As for primary cause of fire. F l a s h p o i n t Non-flammable H a z a r d o u s c o m b u s t i o n p r o d u c t s Not known S E C T I O N 6 - A C C I D E N T A L R E L E A S E M E A S U R E S G e n e r a l Review Sections 3, 8 and 12 before proceeding with clean up. Small spill Wipe up with a damp cloth and place in container for disposal. Clean spill area thoroughly. Prevent discharge to drains. Page 2 of 5
3 S E C T I O N 6 - A C C I D E N T A L R E L E A S E M E A S U R E S... continued L a r g e s p i l l Spills should be handled by vacuuming or wet mopping. Transfer all waste to a labeled container and move it to a secure holding area. Prevent discharge to drains. S E C T I O N 7 - H A N D L I N G A N D S T O R A G E G e n e r a l h a n d l i n g Use with adequate ventilation. Avoid contact with eyes, skin and clothing. Use appropriate personal protective equipment. Avoid breathing dust, vapor or mist. S t o r a g e c o n d i t i o n s Store under refrigeration in closed container. T e m p e r a t u r e r a n g e f o r s t o r a g e 2-7 C S E C T I O N 8 - E X P O S U R E C O N T R O L S / P E R S O N A L P R O T E C T I O N E x p o s u r e l i m i t s Compound Issuer Type OEL Merthiolate (as mercury) OSHA TWA-8 Hr 0.01 mg/m³ (skin) ACGIH TWA-8 Hr 0.1 mg/m³ (skin) E x p o s u r e i n f o r m a t i o n See exposure limits for component (s) listed above. V e n t i l a t i o n General room ventilation is adequate unless the process generates dust, mist or fumes. R e s p i r a t o r y p r o t e c t i o n Respiratory protection is recommended as a precaution to minimize exposure when handling this material in bulk. E y e p r o t e c t i o n Safety glasses or goggles S k i n p r o t e c t i o n Individuals with known sensitivity to penicillin should wear long sleeves to avoid skin contact. Wash hands and arms thoroughly after handling this material. H a n d p r o t e c t i o n Wear impervious gloves if skin contact is possible. S E C T I O N 9 - P H Y S I C A L A N D C H E M I C A L P R O P E R T I E S Physical form Freeze-dried preparation C o l o r No data available M o l e c u l a r w e i g h t Mixture M o l e c u l a r f o r m u l a Mixture p H 7.0 +/- 1.5 standard ph units Page 3 of 5
4 S E C T I O N 9 - P H Y S I C A L A N D C H E M I C A L P R O P E R T I E S... continued B o i l i n g p o i n t >100 C M e l t i n g p o i n t Not applicable D e n s i t y No data available V a p o r p r e s s u r e Expected to be negligible W a t e r s o l u b i l i t y No data available S o l v e n t s o l u b i l i t y No data available S p e c i f i c g r a v i t y 1.0 +/-0.2 S E C T I O N S T A B I L I T Y A N D R E A C T I V I T Y R e a c t i v i t y Stable C o n d i t i o n s t o a v o i d Store at 2-7 C. Prolonged exposure to higher temperatures may adversely affect potency. Do not freeze. I n c o m p a t i b i l i t i e s This material can be denatured or inactivated by a variety of organic solvents, salts or heavy metals. H a z a r d o u s d e c o m p o s i t i o n p r o d u c t s H a z a r d o u s p o l y m e r i z a t i o n None expected under normal conditions. Will not occur S E C T I O N T O X I C O L O G Y I N F O R M A T I O N T o x i c o l o g y s u m m a r y The antigens included in this product are non-infectious. All have been prepared from killed or inactivated preparations of microorganisms. A c u t e t o x i c i t y E y e No data available S k i n No data available Inhalation No data available I n g e s t i o n No data available M u t a g e n i c i t y No data available S e n s i t i z a t i o n This product contains merthiolate which is considered to be a skin sensitizer. Hypersensitivity reactions can occur in individuals sensitive to penicillin, streptomycin, and/or other aminoglycosides. S u b c h r o n i c e f f e c t s No data available Page 4 of 5
5 S E C T I O N T O X I C O L O G Y I N F O R M A T I O N... continued C h r o n i c e f f e c t s / c a r c i n o g e n i c i t y No data available C a r c i n o g e n s t a t u s None of the components of this formulation are listed as a carcinogen by IARC, NTP or OSHA. R e p r o d u c t i v e e f f e c t s Not considered to be a reproductive hazard. S E C T I O N E C O L O G I C A L I N F O R M A T I O N E n v i r o n m e n t a l o v e r v i e w The environmental characteristics of this material have not been fully evaluated. Releases to the environment should be avoided. S E C T I O N D I S P O S A L I N F O R M A T I O N D i s p o s a l p r o c e d u r e Observe all local and national regulations when disposing of this material. This product contains trace quantities of mercury and may qualify as a RCRA Hazardous Waste. Status should be confirmed using the EPA Toxicity Characteristic Leaching Procedure (TCLP). S E C T I O N T R A N S P O R T A T I O N I N F O R M A T I O N G e n e r a l s h i p p i n g i n s t r u c t i o n s Not regulated for transport under USDOT, EUADR, IATA, or IMDG regulations. S E C T I O N R E G U L A T O R Y I N F O R M A T I O N E U C l a s s i f i c a t i o n Not classified C a l i f o r n i a P r o p o s i t i o n 6 5 Aminoglycosides (Streptomycin); Mercury (as Merthiolate) Canadian WHMIS This product has been classified in accordance with the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR. S E C T I O N O T H E R D i s c l a i m e r Pfizer Inc believes that the information contained in this Material Safety Data Sheet is accurate. While Pfizer provides this information in good faith, it does not expressly or impliedly warrant its accuracy. Page 5 of 5
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