Mobile NMR: past, presence, future. PBlü P. Blümlerl ICG-3 Phytosphere, Research Center Jülich, Germany

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1 Mobile NMR: past, presence, future PBlü P. Blümlerl ICG-3 Phytosphere, Research Center Jülich, Germany

2 ...not this kind of mobile! Supercon on a truck

3 NMR-MagnetometerM t Earth magnetic field: ca μt NMR for 1 H: kH 2.5 khz EPR for e - : MHz

4 Portable NMR: J. G. Powles, The New Scientist, January 1st, 1959 A portable nuclearfree precession magnetometer built by Mr. P. Mansfield

5 Two commercial, portable NMR-magnetometers:

6 A Miniature Magnetometer: G. Boero, P.A. Besse et al. Proc.Eurosensors XI, 1 (1997), 263 single silicon chip low cost CMOS technology) a HF generator, a coil with a sample and a signal detection and processing subsystem. cost reduction high spatial resolution (1 mm 3 ) proposed for CW, pulsed NMR, DNP and EPR

7 Applications of Magnetometers: Exploration of groundwater, gold mine, minerals, hydrothermal energy, archaeology, treasure hunting sea land air

8 signa μ V] The NMR Hydroscope O. A. Shushakov, Geophysics 61 (1996) 998 surface coil 100 m principle m water y al ampli itude [ V m m calculated flip-angle dependence current pulse [A s]

9 Oil Well Prospection:

10 Inside-Out NMR S N "homogeneous" region of B 0 R. L.Kleinberg in: D. M. Grant, R. K. Harris,eds., Encyclopedia of NMR, Wiley, New York, 1996, p S 10 cm N half-coaxial antenna

11

12 Typical result

13 Even more extreme...

14 the sonde Suggested Uses of Inside-Out NMR J. A. Jackson, L. J. Burnett, F. Harmon, J. Magn. Reson. 41 (1980) 411 homogeneous M-field potential applications

15 NMR on the Factory Floor: Oxford Instruments, Wyndyke Furlong, UK off-line analysis on-line analysis

16 Foxboro, Massachussetts

17 PCT: Process Control Technology NMR Analyzers for Research, Process Control, and Quality Control com

18 Bruker Analytik, Rheinstetten tt INCA: integrated NMR chemical analyzer at-line process control fully enclosed NMR system no special NMR skills needed d ultra-shield magnet 5 Gauss line within enclosure 300 MHz or 400 MHz

19 Intermagnetics General Corporation Latham, New York MR inspection: packaged goods, spoilage of food moisture in butadiene rubber: 10 kg sample from a production bale, photo and NMR image

20 Tesla Corp. UK on-line monitoring e.g. of food products field:??t

21 Quantum Magnetics Process/Quality Control of Food Products Process/Quality Control of Materials

22 InVision Technologies: Quantum Magnetics explosives/narcotics detection by NQR landmine detection QScan QR 500: can operate QScan QR 160: in with x-ray systems 500 bags per hour

23 FONAR Field Focussed Nuclear Magnetic Resonance R. Damadian et al., Science 194 (1976) 1430

24 magnet Stray-Field Imaging: g STRAFI B z 0 magnetic field z G z 0 gradient z A. A. Samoilenko et al., Bruker Report 2 (1987) 30 R. Kimmich i et al., J. Magn. Reson. 91 (1991) 136

25 Some weird ideas in 1993

26 The NMR-MOUSEMOUSE TM B 0 B 1

27 BIG or Small Mice?

28

29 Southwest Research, San Antonio, Texas magnetic resonance materials analysis, Dr. Armando De Los Santos Moisture in building materials Fraunhofer Institut für zerstörungsfreie Materialprüfung, Saarbrücken, Germany

30 MR Resources, Inc. Gardner, MA, 01440, USA 15 MHz NMR relaxation spectrometer from IIC. This robust and simple-to-use system is dedicated to the routine measurement of relaxation parameters in industrial samples, especially rubbers and polymers. It should be ideal for QA and QC applications in an industrial environment IIC Innovative Imaging Corp. KG Dr. Winfried Kuhn, Blieskastel, Germany

31 Bruker Analytik Rheinstetten NMR quality control

32

33 Resonance Instruments benchtop NMR stray-field imaging 7 MHz core analyzer digital NMR/MRI console portable NMR: magnet and spectrometer

34 Single-Sided or Surrounding? G. Dunn, M. Mallett

35 z Single Sided Double Sided r

36 Applications:

37 The NMR-Monkey University of Wageningen, NL Prof. H. van As

38 Single-Sided Sided Imaging g C. W. Crawley, F. H. Rose, US Patent 5,304,930, Apr. 19, 1994: remotely positioned MRI system

39 Single-Sided Imaging Dr. R. Krieg, Nürnberg Sergio Pissanetzky, Texas

40 Dedicated MRI ESAOTE, Italy ARTOSCAN limb imager

41 MRI: Mouse Refined for Imaging Lateral: Prado & Blümich Depth: Brown & Verganelakis

42 Rings: The NIMBUS G. Dunn, N. Routley, M. Mallett

43 Klaus Hallbach

44 Circular Hallbach Geometries

45 Magic Ring 4 field: ca 0 75 T field: ca T for FeNdB40

46 Magic Ring 8 field: ca 0 65 T field: ca T for FeNdB40

47 Magic Ring 16 field: ca 0 35 T field: ca T for FeNdB40

48 3D MRI-Version from Magneticasoft webpage

49 Another Problem: RF Acoustic Ringing Noise Pickup Bandwidth S/N Penetration Depth

50 Applications Moisture content (free/bound water) Oil content (droplet size distributions) Component analysis (soft matter, models!) Solids/Liquids/Particle /P l size Porous Media (relaxation/diffusion) Reaction analysis (kinetics, components) Isotope distribution ( 1 H, 19 F, 31 P...) EPR? Cryoporometry Imaging In situ In vivo On-line

51 Necessary Improvements: Magnet design: RF-excitation: New Visions: NMR-MOUSE (general purpose) problem dedicated designs new materials (FeNdB 53 MGOe) Q-switching bandwidth/power stochastic excitation background (inorg. substrates: SiO 2, Al 2 O 3 ) coils (superconducting, arrays?) Remote Detection HP gases smaller, homogeneity, pulse sequences

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