PEARL VS RUBIN (GELMAN)

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1 PEARL VS RUBIN (GELMAN) AN EPIC battle between the Rubin Causal Model school (Gelman et al) AND the Structural Causal Model school (Pearl et al) a cursory overview Dokyun Lee

2 WHO ARE THEY? Judea Pearl UCLA Computer Science V S Don B. Rubin Harvard Statistics Probabilistic approach to AI Contributed to the development of Bayesian networks (belief propagation, graphical models - subsumes many stat models such as Kalman filtering, Markov models, Ising models etc) One of the first to mathematize causal modeling in the empirical sciences. Developing a method of causal and counterfactual inference based on structural models Rubin Causal Model Pioneer of Observational studies Causal inference in experiments and observational studies Inference in sample surveys with nonresponse and in missing data problems Advised by Cochran

3 ACTUALLY INVOLVED Judea Pearl UCLA Computer Science V S Andrew Gelman Columbia Statistics Probabilistic approach to AI Contributed to the development of Bayesian networks (belief propagation, graphical models - subsumes many stat models such as Kalman filtering, Markov models, Ising models etc) One of the first to mathematize causal modeling in the empirical sciences. Developing a method of causal and counterfactual inference based on structural models Advised by Don Rubin Prominent Bayesian Statistician with a famous blog Some may already know him from STAT 542 textbook. Applies Bayesian analysis to Political Science

4 SOME POSTS TO GIVE YOU AN IDEA Andrew Columbia University author of many books including Bayesian Data Analysis used in STAT 542 Larry CMU author of the purple book All of Statistics + other book Also involved (some indirectly, some only by their papers): Philip Dawid, Jeff Wooldridge, Dehejia and Wahba, Imbens, Michael Sobel + lot more, of course Paul Rosenbaum is mentioned many times. Total 6 long blog entrees, 91 comments by many leader of the field, many research letters and notes

5 SOME MORE BACKGROUND Causality 2009 Second edition by Judea Pearl: The method of propensity score is based on a simple, yet ingenious, idea of purely statistical character [...] The condition was articulated in the cryptic language of potential outcome, stating that the set [X] must render [Z] Strongly ignorable, i.e., {Y_0,Y_1} ind [Z] [X]. As stated several times in this book, the opacity of ignorability is the Achilles heel of the potentialoutcome approach - no mortal can apply this condition to judge whether it holds even in simple problems, with all causal relationships correctly specified, let alone in partially specified problems that involve dozens of variables.

6 THE BEGINNING 1: 2008, Letter to the editor of Statistics in Medicine, Ian Shrier presented a question to Don Rubin. Is it possible that, asymptotically, the use of Propensity Scores (PS) methods may actually increase, not decrease, overall bias, compared with the crude, unadjusted estimate of a causal effect? 2: Shrier, Sjolander, and Pearl sent three separate letters to Statistics in Medicine in which M-bias was explained and exemplified 3: 2009 Rubin in response: To avoid conditioning on some observed covariates in the hope of obtaining an unbiased estimator because of phantom but complementary imbalances on unobserved covariates, is neither Bayesian nor scientifically sound but rather it is distinctly frequentist and nonscientific ad hocery. 4: 2009, Judea Pearl Myth, Confusion, and Science in Causal Analysis 2009 Statistics in Medicine. Of course, Yes; the M-graph model presented by Shrier provides a simple such example [...] Rubin pleaded to be puzzled and confused by the terminology, by the example, and by graphs in general

7 WHAT IS THIS M-BIAS? Rests on Berkson Paradox Two independent causes of a common effect become dependent when we observe the effect; information refuting one cause should make the other more likely. e.g. outcome: late to Stat 921 one reason: woke up super late second reason: had to save the world again woke up late saved world P(save world = yes late = yes )!= P(save world = yes late = yes,woke up late = no ) Thus save world is not independent of woke up late given late

8 BAYES BALL ALGORITHM

9

10 SUPER SIMPLIFIED VERSION OF THEIR PHILOSOPHY Judea Pearl UCLA Computer Science V S Don B. Rubin Harvard Statistics Causality doesn t come without manipulation Granger Causality is not causality Set up a causal model with graphical models and determine the relationship between the variables. In words of Gelman: The research programme under which all causal inference problems can be framed in terms of graphs, colliders, the do operator, and the like What we ve been learning all along in the course. In words of Gelman: The research programme under which all causal inference problems can be framed in terms of potential outcomes

11 ONE ISSUE RAISED AMONG MANY (BACK TO M-BIAS) Rubin: Condition on all pre-treatment variables Pearl: Do not condition on all information lest some confounders introduce more bias. graphical models: helpful or not.

12 SOME PAPERS ON THIS ISSUE Brookhard, M. Alan, Sebastian Schneeweiss, Kenneth J. Rothman, Robert J. Glynn, Jerry Avorn, & Til Stu rmer Variable selection for propensity score models. American Journal of Epidemiology 163 (June): Kevin A. Clarke, Brenton Kenkel, and Miguel R. Rueda. Misspecification and the propensity score: when to leave out relevant pre-treatment variables. preprint, Soko Setoguchi, Sebastian Schneeweiss, M. Alan Brookhart, Robert J. Glynn, and E. Francis Cook. Evaluating uses of data mining techniques in propensity score estimation: a simulation study. Pharmacoepidemiology and drug safety, 17(6): , June etc

13 SOME CLAIMS AMONG COUNTLESS MANY Judea Pearl Andrew Gelman Rubin model is a particular case of Pearl model. Rubin model is not explicit when it comes to ignorability condition Judea Pearl may have proven equivalence of the Rubin model and the Pearl model but assumptions are wrong or irrelevant for some real world problems.

14 STRUCTURAL CAUSAL MODEL BOOKS Causality By Judea Pearl (UCLA), 2009, Cambridge University Press. Targeted Learning by Mark Van Der Laan (UCB) and Sherri Rose (Johns Hopkins), 2011, Springer Series in Statistics

15 REFERENCES published/causalreview4.pdf

UCLA Department of Statistics Papers

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