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1 The Stata Journal Editor H. Joseph Newton Department of Statistics Texas A&M University College Station, Texas ; fax Associate Editors Christopher F. Baum Boston College Nathaniel Beck New York University Rino Bellocco Karolinska Institutet, Sweden, and University of Milano-Bicocca, Italy Maarten L. Buis Tübingen University, Germany A. Colin Cameron University of California Davis Mario A. Cleves Univ. of Arkansas for Medical Sciences William D. Dupont Vanderbilt University David Epstein Columbia University Allan Gregory Queen s University James Hardin University of South Carolina Ben Jann University of Bern, Switzerland Stephen Jenkins University of Essex Ulrich Kohler WZB, Berlin Frauke Kreuter University of Maryland College Park Stata Press Editorial Manager Stata Press Copy Editors Editor Nicholas J. Cox Department of Geography Durham University South Road Durham DH1 3LE UK n.j.cox@stata-journal.com Peter A. Lachenbruch Oregon State University Jens Lauritsen Odense University Hospital Stanley Lemeshow Ohio State University J. Scott Long Indiana University Roger Newson Imperial College, London Austin Nichols Urban Institute, Washington DC Marcello Pagano Harvard School of Public Health Sophia Rabe-Hesketh University of California Berkeley J. Patrick Royston MRC Clinical Trials Unit, London Philip Ryan University of Adelaide Mark E. Schaffer Heriot-Watt University, Edinburgh Jeroen Weesie Utrecht University Nicholas J. G. Winter University of Virginia Jeffrey Wooldridge Michigan State University Lisa Gilmore Deirdre Patterson and Erin Roberson

2 The Stata Journal publishes reviewed papers together with shorter notes or comments, regular columns, book reviews, and other material of interest to Stata users. Examples of the types of papers include 1) expository papers that link the use of Stata commands or programs to associated principles, such as those that will serve as tutorials for users first encountering a new field of statistics or a major new technique; 2) papers that go beyond the Stata manual in explaining key features or uses of Stata that are of interest to intermediate or advanced users of Stata; 3) papers that discuss new commands or Stata programs of interest either to a wide spectrum of users (e.g., in data management or graphics) or to some large segment of Stata users (e.g., in survey statistics, survival analysis, panel analysis, or limited dependent variable modeling); 4) papers analyzing the statistical properties of new or existing estimators and tests in Stata; 5) papers that could be of interest or usefulness to researchers, especially in fields that are of practical importance but are not often included in texts or other journals, such as the use of Stata in managing datasets, especially large datasets, with advice from hard-won experience; and 6) papers of interest to those who teach, including Stata with topics such as extended examples of techniques and interpretation of results, simulations of statistical concepts, and overviews of subject areas. For more information on the Stata Journal, including information for authors, see the webpage The Stata Journal is indexed and abstracted in the following: CompuMath Citation Index R Current Contents/Social and Behavioral Sciences R RePEc: Research Papers in Economics Science Citation Index Expanded (also known as SciSearch R ) Scopus TM Social Sciences Citation Index R Copyright Statement: The Stata Journal and the contents of the supporting files (programs, datasets, and help files) are copyright c by StataCorp LP. The contents of the supporting files (programs, datasets, and help files) may be copied or reproduced by any means whatsoever, in whole or in part, as long as any copy or reproduction includes attribution to both (1) the author and (2) the Stata Journal. The articles appearing in the Stata Journal may be copied or reproduced as printed copies, in whole or in part, as long as any copy or reproduction includes attribution to both (1) the author and (2) the Stata Journal. Written permission must be obtained from StataCorp if you wish to make electronic copies of the insertions. This precludes placing electronic copies of the Stata Journal, in whole or in part, on publicly accessible websites, fileservers, or other locations where the copy may be accessed by anyone other than the subscriber. Users of any of the software, ideas, data, or other materials published in the Stata Journal or the supporting files understand that such use is made without warranty of any kind, by either the Stata Journal, the author, or StataCorp. In particular, there is no warranty of fitness of purpose or merchantability, nor for special, incidental, or consequential damages such as loss of profits. The purpose of the Stata Journal is to promote free communication among Stata users. The Stata Journal (ISSN X) is a publication of Stata Press. Stata, Mata, NetCourse, and Stata Press are registered trademarks of StataCorp LP.

3 The Stata Journal (2010) 10, Number 3, pp Stata tip 89: Estimating means and percentiles following multiple imputation Peter A. Lachenbruch Oregon State University Corvallis, OR 1 Introduction In a statistical analysis, I usually want some basic descriptive statistics such as the mean, standard deviation, extremes, and percentiles. See, for example, Pagano and Gauvreau (2000). Stata conveniently provides these descriptive statistics with the summarize command s detail option. Alternatively, I can obtain percentiles with the centile command. For example, with auto.dta, we have. sysuse auto (1978 Automobile Data). summarize price, detail Price Percentiles Smallest 1% % % Obs 74 25% Sum of Wgt % Mean Largest Std. Dev % % Variance % Skewness % Kurtosis However, if I have missing values, the summarize command is not supported by mi estimate or by the user-written mim command (Royston 2004, 2005a,b, 2007; Royston, Carlin, and White 2009). 2 Finding means and percentiles when missing values are present For a general multiple-imputation reference, see Stata 11 Multiple-Imputation Reference Manual (2009). By recognizing that a regression with no independent variables estimates the mean, I can usemi estimate: regress to get multiply imputed means. If I wish to get multiply imputed quantiles, I can use mi estimate: qreg or mi estimate: sqreg for this purpose. c 2010 StataCorp LP st0205

4 P. A. Lachenbruch 497 I now create a dataset with missing values of price:. clonevar newprice = price. set seed replace newprice =. if runiform() <.4 (32 real changes made, 32 to missing) The following commands were generated from the multiple-imputation dialog box. I used 20 imputations. Before Stata 11, this could also be done with the user-written commands ice and mim (Royston 2004, 2005a,b, 2007; Royston, Carlin, and White 2009).. mi set mlong. mi register imputed newprice (32 m=0 obs. now marked as incomplete). mi register regular mpg trunk weight length. mi impute regress newprice, add(20) rseed( ) Univariate imputation Imputations = 20 Linear regression added = 20 Imputed: m=1 through m=20 updated = 0 Observations per m Variable complete incomplete imputed total newprice (complete + incomplete = total; imputed is the minimum across m of the number of filled in observations.). mi estimate: regress newprice Multiple-imputation estimates Imputations = 20 Linear regression Number of obs = 74 Average RVI = Complete DF = 73 DF: min = avg = DF adjustment: Small sample max = F( 0,.) =. Within VCE type: OLS Prob > F =. newprice Coef. Std. Err. t P> t [95% Conf. Interval] _cons From this output, we see that the estimated mean is 5,693 with a standard error of 455 (rounded up) compared with the complete data value of 6,165 with a standard error of 343 (also rounded up). However, we do not have estimates of quantiles. This could also have been done using mi estimate: mean newprice (the mean command is near the bottom of the estimation command list for mi estimate).

5 498 Stata tip 89 We can apply the same principle using qreg. For the 10th percentile, type. mi estimate: qreg newprice, quantile(10) Multiple-imputation estimates Imputations = 20.1 Quantile regression Number of obs = 74 Average RVI = Complete DF = 73 DF: min = avg = DF adjustment: Small sample max = F( 0,.) =. Prob > F =. newprice Coef. Std. Err. t P> t [95% Conf. Interval] _cons Compare the value of 3,496 with the value of 3,895 from the full data. We can use the simultaneous estimates command for the full set:. mi estimate: sqreg newprice, quantiles( ) reps(20) Multiple-imputation estimates Imputations = 20 Simultaneous quantile regression Number of obs = 74 Average RVI = Complete DF = 73 DF adjustment: Small sample DF: min = avg = max = newprice Coef. Std. Err. t P> t [95% Conf. Interval] q10 q25 q50 q75 q90 _cons _cons _cons _cons _cons Comments and cautions The qreg command does not give the same result as the centile command when you have complete data. This is because the centile command uses one observation, while the qreg command uses a weighted combination of the observations. It will have somewhat shorter confidence intervals, but with large datasets, the difference will be

6 P. A. Lachenbruch 499 small. A second caution is that comparing two medians can be tricky: the difference of two medians is not the median difference of the distributions. I have found it useful to use percentiles because there is a one-to-one relationship between percentiles if data are transformed. In our case, there is plentiful evidence that price is not normally distributed, so it would be good to look for a transformation and impute those values. This method of using regression commands without an independent variable can provide estimates of quantities that otherwise would be difficult to obtain. For example, it is much faster than finding 20 imputed percentiles and then combining them with Rubin s rules, and it is much less onerous and prone to error. 4 Acknowledgment This work was supported in part by a grant from the Cure JM Foundation. References Pagano, M., and K. Gauvreau Principles of Biostatistics. 2nd ed. Belmont, CA: Duxbury. Royston, P Multiple imputation of missing values. Stata Journal 4: a. Multiple imputation of missing values: Update. Stata Journal 5: b. Multiple imputation of missing values: Update of ice. Stata Journal 5: Multiple imputation of missing values: Further update of ice, with an emphasis on interval censoring. Stata Journal 7: Royston, P., J. B. Carlin, and I. R. White Multiple imputation of missing values: New features for mim. Stata Journal 9: StataCorp Stata 11 Multiple-Imputation Reference Manual. College Station, TX: Stata Press.

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