SAS program: SAB_blood_table_figure_TEQ1998_DF Procedure: PROC B Created by: BH Last Update: WC & BH 06/30/2007

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1 BLOOD DIOXIN CONCENTRATIONS: Wightd TEQ DF by rgion Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs TEQ DF (ppt) Zon N Man S.E. Mdian 75th %il 95th %il Min. Max. Ovrall M/S FP M/S Nar FP M/S Out FP M/S Plum Jackson/Calhoun M/S: Midland/Saginaw FP: Floodplain Procdur: PROC B

2 BLOOD DIOXIN CONCENTRATIONS: Wightd TEQ DF by rgion Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs 50 Ovrall Distribution of TEQ_DF (N=946) 40 Man 20.1 Minimum 3.0 Mdian 17.1 Maximum P r c n t Blood TEQ_DF Curv: Normal(Mu=20.13 Sigma=12.779) 17.5 Ovrall Distribution of log10(teq_df )(n=946) P r c n t Man 1.2 Minimum 0.5 Mdian 1.2 Maximum Curv: log(blood TEQ_DF ) Normal(Mu= Sigma=0.2515) Procdur: PROC C

3 BLOOD DIOXIN CONCENTRATIONS: Wightd TEQ DF by Ag group and rgion Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs TEQ DF (ppt) Ag Group Zon N Man S.E. Mdian 75th %il 95th %il Min. Max. Ovrall M/S FP Ag_18_29 M/S Nar FP M/S Out FP M/S Plum Jackson/Calhoun Ovrall M/S FP Ag_30_44 M/S Nar FP M/S Out FP M/S Plum Jackson/Calhoun Ovrall M/S FP Ag_45_59 M/S Nar FP M/S Out FP M/S Plum Jackson/Calhoun Ovrall M/S FP Ag_60_mor M/S Nar FP M/S Out FP M/S Plum Jackson/Calhoun M/S: Midland/Saginaw FP: Floodplain Procdur: PROC F

4 BLOOD DIOXIN CONCENTRATIONS: Tst rsults for comparing wightd TEQ DF among rgions Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs Summary statistics for blood wightd TEQ DF concntration for rgion comparisons Rgion Arithmtic man of TEQ Man of log 10 TEQ SAS program: blood_rgiontst_teq1998_df.sas ; Last Updat: WC & BH 6/30/2007 % > Jackson/Calhoun's 75 th prcntil, which is 21.1 ppt % > Jackson/Calhoun's 95 th prcntil, which is 38.6 ppt 1-M/S FP (n=243) % 10.1% 2-M/S Nar FP (n=205) % 8.8% 3-M/S Out FP (n=204) % 13.6% 4-M/S Plum (n=43) % 9.0% 5-Jackson/Calhoun (n=251) % 4.7% M/S: Midland / Saginaw; FP: Floodplain Pair-wis comparisons for blood TEQ DF btwn rgions (Each cll contains th p-valu and ffct dirction) This tabl shows th rsults of 1) t-tsts (SAS PROC Survyrg) for comparisons of th mans of log 10 TEQ btwn ach combination of two rgions; 2) Wald chi-squar tsts (SAS PROC Survylogistic) for comparisons of th odds of subjcts bing abov th 75 th prcntil TEQ for Jackson/Calhoun Countis btwn ach combination of two rgions; and 3) Wald chi-squar tsts (SAS PROC Survylogistic) for comparisons of th odds of subjcts bing abov th 95 th prcntil TEQ for Jackson/Calhoun Countis btwn ach combination of two rgions. "+" aftr p-valu: th row-rgion has highr man or highr odds of bing abov th slctd cut-point than th column-rgion. "-" aftr p-valu: th row-rgion has lowr man or lowr odds of bing abov th slctd cut-point than th column-rgion. P-valu 1-M/S FP 2-M/S Nar FP 3-M/S Out FP 4-M/S Plum 5-Jackson/Calhoun Man of log 10 TEQ %>J/C's %>J/C's Man of 75 th 95 th log 10 TEQ %>J/C's %>J/C's Man of 75 th 95 th log 10 TEQ %>J/C's %>J/C's Man of 75 th 95 th log 10 TEQ %>J/C's %>J/C's 75 th 95 th 1-M/S FP Unadjustd Adjustd M/S Nar FP Unadjustd Adjustd M/S Out FP Unadjustd Adjustd M/S Plum Unadjustd Adjustd Unadjustd: Rgion Only; Adjustd: Rgion + Ag + Ag 2 + BMI; J/C: Jackson/Calhoun

5 WEIGHTED BLOOD CONCENTRATIONS: Contribution of ach congnr to th total TEQ DF , shown using box plots Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs 60 Contribution to Total TEQ_DF (%) _TCDD 12378_PCDD _HxCDD _HxCDD _HxCDD _HpCDD OCDD 2378_TCDF 12378_PCDF 23478_PCDF _HxCDF _HxCDF _HxCDF _HxCDF _HpCDF _HpCDF OCDF Dioxins Furans Procdur: PROC D

6 WEIGHTED BLOOD CONCENTRATIONS: Prcnt contribution to total TEQ DF for dioxins and furans, by rgion, shown using box plots Nots: TEQ DF is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs 100 Contribution to Total TEQ_DF (%) Dioxins Furans Rgion* 1-Midland/Saginaw FP; 2-Midland/Saginaw Nar FP; 3-Midland/Saginaw Out FP; 4-Midland/Saginaw Plum; 5-Jackson/Calhoun Procdur: PROC E

DUST DIOXIN CONCENTRATIONS:

DUST DIOXIN CONCENTRATIONS: Wightd TEQ DF17-1998 by rgion Sampl Typ: dust Nots: TEQ DF17-1998 is th TEF-wightd avrag of th 17 dioxin congnrs (xcluding th PCBs) basd on WHO 1998 TEFs TEQ DF17-1998 (ppt)