The structure and function of biological molecules SI MODULE CODE N CREDITS 20 LEVEL 4 JACS CODE. Independent Guided Study

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1 TITLE The structure ad fuctio of biological molecules SI MODULE CODE N CREDITS 20 LEVEL 4 JACS CODE C700 SUBJECT GROUP FdSc Biosciece ad FdSc Biochemistry DEPARTMENT Bioscieces MODULE LEADER David Cross MODULE STUD HOURS (based o 10 hours per credit) Scheduled Learig ad Teachig Activities Placemet (if applicable) Idepedet Guided Study 52.5 N/A MODULE AIM(S) Total Number of Study Hours The aims of this module are to equip studets with the chemical kowledge ad cocepts ecessary to explai ad uderstad how the structure ad properties of biological molecules relate to their fuctios. It also aims to support studets uderstadig of the biosciece ecoutered i other areas of the course. MODULE LEARNING OUTCOMES By egagig successfully with this module a studet will be able to: 1. Demostrate accurate use of chemical equatios ad formulae i a quatitative maer. 2. Describe the theoretical cocepts relatig to atomic ad molecular structure ad the priciples of covalet ad ioic bodig ad itermolecular iteractios. 3. Idetify ad draw the structures of orgaic molecules, icludig fuctioal groups ad isomers, ad be able to relate these to more complex biologically sigificat compouds. 4. Provide examples of differet types of importat biological molecules ad explai how their bodig ad structure eables them to perform their fuctio. 5. Use appropriate theories to explai the effect of reactio coditios o biological reactios. 6. Udertake laboratory work to obtai qualitative ad quatitative data. Iterpret the data ad draw meaigful coclusios. INDICATIVE CONTENT 1. Basic chemical termiology: elemets, compouds, atoms, ios ad molecules 2. Writig ad balacig chemical equatios ad volumetric aalysis 3. Ioic ad covalet bodig, itermolecular forces 4. Shapes of molecules

2 5. Orgaic molecules: fuctioal groups, homologous series, isomerism, represetatio, basic omeclature 6. Electroegativity, bod polarity, overall molecule polarity, hydrophilic ad hydrophobic structures 7. The structure ad bodig of importat biological molecules ad how their chemical ad physical properties lik to their fuctios. Molecules to be studied will iclude simple ad complex carbohydrates, proteis ad amio acids, lipids, ucleotides ad ucleic acids 8. Ezymes ad reactio kietics 9. Chemical equilibria 10. Acid base equilibria: ph, acids, bases ad buffers ad their importace i biological systems LEARNING AND TEACHING METHODS A rage of methods is used icludig: Lectures ad semiars Laboratory practical sessios Group ad idividual practical activities Idepedet activities through VLE ASSESSMENT STRATEG AND METHODS Task No.* Short Descriptio of Task SI Code EX/C W/PR Task Weightig % Word Cout or Exam Duratio** 1 Scietific Essay CW 40 % 1600 words 2 Practical Examiatio EX 60 % 1.5 Hours Task Descriptios ad SI Codes Scietific Essay (CW) (40%) Studets will write a scietific report of approximately 1600 words describig how the types of bodig ad the structure of specific biological molecules eable them to perform their fuctios. Practical Examiatio (EX) (60%) Studets will be required to perform a practical task uder examiatio coditios. They will be provided with a writte experimetal brief ad required to record relevat data ad results. Studets will be required to demostrate the ability to perform relevat calculatios. O completio of the practical task, studets will be required to aswer pre-set questios to demostrate kowledge, uderstadig ad iterpretatio. I-module retrieval available

3 FEEDBACK Studets will receive feedback o their performace i the followig ways: Studets will be provided with the opportuity to assess their ow progress though formative testig takig place throughout the module The use of costructive ad developmetal peer feedback will be ecouraged throughout the module Summative feedback will be used to help clarify areas of stregth as well as idicate areas for developmet. This feedback will be aliged with relevat module outcome ad provided o assessmet feedback sheet Summative feedback will be provided through methods such as script aotatios, tutorials ad audio files of commets Feedback o examiatio scripts will aim to idetify specific areas for developmet i additio to the presetatio of a percetage mark. LEARNING RESOURCES (INCLUDING READING LISTS) Hill, G. ad Holma, J. (2011) Chemistry i cotext. Chelteham: Thomas Nelso. Clayde, J., Greeves, N., Warre, S. & Wothers, P. (2001). Orgaic Chemistry. Oxford: OUP Clyes, S., Williams, D.J.W. ad Clarke, J.S. (1971) A ew chemistry. Seveoaks: Hodder ad Stoughto. Crowe, J. & Bradshaw, T. (2010). Chemistry for the Bioscieces: The Essetial Cocepts (2d Editio). Oxford: OUP. Housecroft, C. E. & Sharpe, A. G. (2001). Iorgaic Chemistry. New ork: Pearso Pretice Hall. Karty, J. (2005). The Nuts ad Bolts of Orgaic Chemistry: A Studet's Guide to Success. Melo Park, CA: Bejami Cummigs. MORAN, L.A. et al. (o date) Priciples of Biochemistry. 5th ed. Pearso. Voet, D. J., Voet, J. G. & Pratt, C. W. (2008). Priciples of Biochemistry. (3rd Editio). Chichester: Wiley. Much of the key readig ca be foud i the Uiversity Cetre Library. Some of the key readig will be also available via the Uiversity Cetres VLE (Moodle) ad o itues u. Moodle will also be used to provide liks to some relevat e-jourals, e-books ad relevat iteret pages. E-learig through forms such as , discussio forums ad pod casts will be used to develop learig. These will be used i additio to semiars ad workshops, to provide studets with the opportuity to dissemiate ideas, ask questios ad gai additioal iformatio from teachig staff ad peers. Istructioal videos will also provide studets with additioal iformatio ito some relevat testig/aalysis procedures that are required as part

4 of the module. These resources will be used to provide a flexible ad iteractive learig eviromet, ehacig studets adherece ad motivatio to the course ad also the ability to become a more autoomous studet.

5 SECTION 2: MODULE INFORMATION FOR STAFF ONL MODULE DELIVER AND ASSESSMENT MANAGEMENT INFORMATION MODULE STATUS - INDICATE IF AN CHANGES BEING MADE NEW MODULE EXISTING MODULE - NO CHANGE Title Chage Level Chage Credit Chage Assessmet Patter Chage Chage to Delivery Patter Date the chages (or ew module) will be implemeted 2/17 MODULE DELIVER PATTERN Give details of the start ad ed dates for each module. If the course has more tha oe itake, for example, September ad Jauary, please give details of the module start ad ed dates for each itake. Module Begis Module Eds Course Itake 1 11/2/17 21/6/17 Is timetabled cotact time required for this module? Are ay staff teachig o this module o-shu employees? If yes, please give details of the employer istitutio(s) below North Lidsey College What proportio of the module is taught by these o-shu staff, expressed as a percetage? 100 % MODULE ASSESSMENT INFORMATION Idicate how the module will be marked *Overall PERCENTAGE Mark of 40% *Overall PASS / FAIL Grade N *Choose oe oly module caot iclude both percetage mark ad pass/fail graded tasks SUB-TASKS Will ay sub-tasks (activities) be used as part of the assessmet N strategy for this module? If sub-tasks / activities are to be used this must be approved withi the Faculty prior to approval. Sub-task / activity marks will be recorded locally ad exteuatig circumstaces, extesios, referrals ad deferrals will ot apply to sub-tasks / activities. FINAL TASK Accordig to the Assessmet Iformatio show i the Module Descriptor, which task will be the LAST TASK to be take or hadedi? (Give task umber as show i the Assessmet Iformatio Grid i Sectio 1 of the Descriptor) Task No. 1

6 REVISIONS Date Feb 2016 Reaso Module Modificatio -DB2BC

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