Dr Daniel Allwood. Independent Guided Study

Transcription

1 MODULE DESCRIPTOR TITLE Fundamentals of Organic Chemistry SI MODULE CODE L CREDITS 20 LEVEL 4 JACS CODE F160 SUBJECT GROUP Biosciences DEPARTMET Biosciences MODULE LEADER Dr Daniel Allwood MODULE STUD HOURS (based on 10 hours per credit) Scheduled Learning and Teaching Activities Placement (if applicable) Independent Guided Study MODULE AIM Total umber of Study Hours This module aims to provide you with underpinning knowledge of organic chemistry. It involves the study of the common reactions which organic functional groups undergo and to further develop the skills required for using this knowledge base in organic synthesis and organic spectroscopy. MODULE LEARIG OUTCOMES By engaging successfully with this module a student will be able to 1. Describe and define the three-dimensional structures and shapes of molecules 2. Identify and describe the reactions of a range of common functional groups and their use in synthesis including the mechanisms by which these reactions occur 3. Understand the stereochemical aspects associated with reactions at saturated carbon 4. Describe electrophilic substitution reactions of benzene and apply this knowledge to make a range of di- and tri-substituted aromatics compounds 5. Discuss experimental approaches to organic spectroscopy suitable for a range of simple compounds and be familiar with instrument parameters 6. Describe how information from 1 HMR, 13 CMR, IR and Mass spectra can be used to give structural information IDICATIVE COTET Functional groups and nomenclature ucleophiles, electrophiles and curly arrows to show reaction mechanisms Stereochemistry. Structural isomerism and stereoisomerism. Optical isomerism: chirality, enantiomers, diastereomers, meso compounds, Fischer projections and specification of configuration (R/S system). Geometrical isomerism: (E/Z system). Conformational isomerism in butane and cyclohexane systems. Simple reactions of functional groups e.g. alkyl halides, alkenes, aldehydes, ketones, alcohols, amines, carboxylic acids, esters, electrophilic aromatic substitution chemistry. Stereochemistry of addition and substitution reactions.

2 Preparation and use of organo-lithium and organo-magnesium reagents in organic synthesis Electrophilic aromatic substitution reactions of benzene 1 HMR spectroscopy: chemical shift, integrals, coupling patterns and coupling constants. 13 CMR spectroscopy: chemical shift, coupling and decoupling. Infrared spectroscopy: functional group and fingerprint regions; interpretation of IR spectra. Organic mass spectrometry: fragmentations and functional group oriented fragmentations and rearrangements; use of EI libraries Complementary use of IR, 1 H MR, 13 C MR spectroscopy and mass spectrometry in structural elucidation of organic compounds. LEARIG AD TEACHIG METHODS Students will be supported in their learning, to achieve the above outcomes, in the following ways: Learning and teaching activities will include a mixture of lectures and whole group tutorials. Self-directed studies will reinforce this information and students will be encouraged to consolidate and extend lecture material from recommended standard textbooks and online sources. Students will examine and broaden the synthetic application of knowledge acquired by doing a variety of formative problem solving exercises. The module Blackboard site will acts as a repository for course information and learning support material, assessment activities and feedback. ASSESSMET STRATEG AD TASK IFORMATIO The module will be assessed through a combination of coursework an end of module exam. Coursework Workbook (40%) A workbook will be provided at the start of the module. This approach will allow students to practice relevant problems and prepare themselves with better understanding for the summative assessments on the whole. Moreover, students will receive rapid feedback and support for topics with which they have difficulty in understanding. Examination (60%) o. Short Description of SI Code EX/CW/PR Weighting % Word Count or Exam Duration 1 Workbook 40 na 2 Examination 60 3 hours In-module retrieval available FEEDBACK

3 Students will receive feedback on their performance in the following ways: Verbal feedback may be given on a whole group or individual basis in lectures and tutorials. Written and verbal comments will be provided on summative coursework exercise. Formative tests performed on the VLE will provide a level of instant feedback and marked work will be returned with tutor feedback. Feedback on the examination will be in accordance with university policy LEARIG RESOURCES (ICLUDIG READIG LISTS) Primary Source: Clayden, J., Greeves,. and Warren, S. (2012) Organic Chemistry Oxford University Press. Supplementary reading: Jones,Jr., M. and Fleming, S.A., (2010) Organic Chemistry 4 th Ed. orton & Co. Loudon, G. M., (2009) Organic chemistry, Oxford press. McMurray, J., (2011) Organic chemistry, 8 th ed. Thompson. Morrison, R.T. and Boyd, R.., Organic chemistry, 7 th ed Prentice-Hall. Streitweiser, JR, A. And Heathcock, C.H., Organic chemistry, Macmillan.

4 SECTIO 2 MODULE IFORMATIO FOR STAFF OL MODULE DELIVER AD ASSESSMET MAAGEMET IFORMATIO MODULE STATUS - IDICATE IF A CHAGES BEIG MADE EW MODULE EXISTIG MODULE - O CHAGE Title Change Level Change Credit Change Assessment Pattern Change Change to Delivery Pattern Date the changes (or new module) will be implemented 09/2012 MODULE DELIVER PATTER Give details of the start and end dates for each module. If the course has more than one intake, for example, September and January, please give details of the module start and end dates for each intake. Module Begins Module Ends Course Intake 1 09/ /2013 Course Intake 2 A A Course Intake 3 A A Is timetabled contact time required for this module? Are any staff teaching on this module non-shu employees? If yes, please give details of the employer institution(s) below What proportion of the module is taught by these non-shu staff, expressed as a percentage? MODULE ASSESSMET IFORMATIO Indicate how the module will be marked *Overall PERCETAGE Mark of 40% *Overall PASS / FAIL Grade *Choose one only module cannot include both percentage mark and pass/fail graded tasks SUB-TASKS Will any sub-tasks (activities) be used as part of the assessment strategy for this module? If sub-tasks / activities are to be used this must be approved within the Faculty prior to approval. Sub-task / activity marks will be recorded locally and extenuating circumstances, extensions, referrals and deferrals will not apply to sub-tasks / activities. FIAL TASK According to the Assessment Information shown in the Module Descriptor, which task will be the LAST TASK to be taken or handed-in? (Give task number as shown in the Assessment Information Grid in Section 1 of the Descriptor) o. 2 MODULE REFERRAL STRATEG - TASK FOR TASK BASIS OL (FROM 2012/13)

5 CHECKED Date Aug 2012 Reason Checked Against SI