Chapter 21. Phenols and Aryl Halides. Nucleophilic Aromatic Substitution. Ch. 21-1

24.4: Acidity of Phenols. Phenols are more acidic than aliphatic alcohols. + Electron-withdrawing groups make an O

Chapter 24: Phenols. Alcohols contain an group bonded to an sp 3 -hybridized carbon. Phenols contain an group bonded to an sp 2 -hybridized carbon of a benzene ring 24.1: Nomenclature (please read) 24.2:

Chapter 23 Phenols CH. 23. Nomenclature. The OH group takes precedence as the parent phenol.

CH. 23 Chapter 23 Phenols Nomenclature The OH group takes precedence as the parent phenol. Carboxyl and acyl groups take precedence over the OH group. The OH group is a strong electron-donating group through

CHAPTER 12. Substituted Benzene

CHAPTER 12 Substituted Benzene 12.1 Alkylbenzenes (Ar-R) Bezylic carbons: CH 3 CH 2 CH 3 CH(CH 3 ) 2 1 Reactions of Alkylbenzens 1. Free Radical Halogenation CH 2 CH 3 Br 2 hv Br CHCH 3 2 2- xidation R

Chapter 17 Reactions of Aromatic Compounds. Electrophilic Aromatic Substitution

Chapter 17 Reactions of Aromatic Compounds Electrophilic Aromatic Substitution Electrophile substitutes for a hydrogen on the benzene ring. Chapter 17: Aromatics 2-Reactions Slide 17-2 1 Mechanism Step

William H. Brown & Christopher S. Foote

William. Brown & Christopher S. Foote Requests for permission to make copies of any part of the work should be mailed to:permissions Department, arcourt Brace & Company, 6277 Sea arbor Drive, Orlando,

Reactions of Aromatic Compounds

2-1 Reactions of Aromatic Compounds 15.1 2-2 lectrophilic Aromatic Substitution Reactions Aromatic hydrocarbons (= arenes) undergo a substitution reaction with electrophiles: + catalyst + xample: omination

ORGANIC - BROWN 8E CH. 22- REACTIONS OF BENZENE AND ITS DERIVATIVES

!! www.clutchprep.com CONCEPT: ELECTROPHILIC AROMATIC SUBSTITUTION GENERAL MECHANISM Benzene reacts with very few reagents. It DOES NOT undergo typical addition reactions. Why? If we can get benzene to

Lecture Topics: I. Electrophilic Aromatic Substitution (EAS)

Reactions of Aromatic Compounds Reading: Wade chapter 17, sections 17-1- 17-15 Study Problems: 17-44, 17-46, 17-47, 17-48, 17-51, 17-52, 17-53, 17-59, 17-61 Key Concepts and Skills: Predict and propose

Ch.16 Chemistry of Benzene: Electrophilic Aromatic Substitution

Ch.16 Chemistry of Benzene: Electrophilic Aromatic Substitution Electrophilic aromatic substitution: E + E + + Some electrophilic aromatic substitution: X N 2 S 3 R C R alogenation Nitration Sulfonation

23.5 Nucleophilic Substitution in Nitro-Substituted Aryl Halides

23.5 Nucleophilic Substitution in Nitro-Substituted Aryl alides nitro-substituted aryl halides do undergo nucleophilic aromatic substitution readily Cl OC 3 + NaOC 3 C 3 O 85 C + NaCl NO 2 NO 2 (92%) Effect

Organic Chemistry, 7 L. G. Wade, Jr. Chapter , Prentice Hall

Organic Chemistry, 7 th Edition L. G. Wade, Jr. Chapter 17 Reactions of Aromatic Compounds 2010, Prentice Hall Electrophilic Aromatic Substitution Although h benzene s pi electrons are in a stable aromatic

Chapter 16 Chemistry of Benzene: Electrophilic Aromatic Substitution

John E. McMurry www.cengage.com/chemistry/mcmurry Chapter 16 Chemistry of Benzene: Electrophilic Aromatic Substitution Paul D. Adams University of Arkansas Substitution Reactions of Benzene and Its Derivatives

16. Chemistry of Benzene: Electrophilic Aromatic Substitution. Based on McMurry s Organic Chemistry, 7 th edition

16. Chemistry of Benzene: Electrophilic Aromatic Substitution Based on McMurry s Organic Chemistry, 7 th edition Substitution Reactions of Benzene and Its Derivatives Benzene is aromatic: a cyclic conjugated

Aryl Halides. Structure

Aryl Halides Structure Aryl halides are compounds containing halogen attached directly to an aromatic ring. They have the general formula ArX, where Ar is phenyl, substituted phenyl. X= F,Cl,Br,I An aryl

BRCC CHM 102 Class Notes Chapter 13 Page 1 of 6

BRCC CHM 102 ass Notes Chapter 13 Page 1 of 6 Chapter 13 Benzene and Its Derivatives aliphatic hydrocarbons include alkanes, alkenes, and alkynes aromatic hydrocarbons compounds that contain one or more

TOPIC 2. REACTIONS OF AROMATIC COMPOUNDS (Chapters 15, parts of 20, and 21)

L TPIC 2. RACTINS F ARMATIC CMPUNDS (Chapters 15, parts of 20, and 21) BJCTIVS 1. Describe the reactions between strong electrophiles and aromatic compounds (the nucleophilc component) which lead to substitution

Lecture 9. Chemistry! Chemistry 328N. February 20, 2018

Lecture 9 Chemistry! February 20, 2018 Some istory Michael Faraday 1791-1867 British physicist and chemist, best known for his discoveries of electromagnetic induction and of the laws of electrolysis.

11/30/ Substituent Effects in Electrophilic Substitutions. Substituent Effects in Electrophilic Substitutions

Chapter 9 Problems: 9.1-29, 32-34, 36-37, 39-45, 48-56, 58-59, 61-69, 71-72. 9.8 Substituent effects in the electrophilic substitution of an aromatic ring Substituents affect the reactivity of the aromatic

12/27/2010. Chapter 15 Reactions of Aromatic Compounds

Chapter 15 Reactions of Aromatic Compounds Electrophilic Aromatic Substitution Arene (Ar-H) is the generic term for an aromatic hydrocarbon The aryl group (Ar) is derived by removal of a hydrogen atom

Examples of Substituted Benzenes

Organic Chemistry 5 th Edition Paula Yurkanis Bruice Examples of Substituted Benzenes Chapter 15 Reactions of Substituted Benzenes Irene Lee Case Western Reserve University Cleveland, OH 2007, Prentice

Lecture 10. More Aromatics. February 18, Chemistry 328N

Lecture 10 More Aromatics February 18, 2016 eterocyclic Aromatic Compounds N N O S Pyridine Pyrrole Furan Thiophene ückel and Pyridine ückel and Pyrrole uckel and Furan Recognizing Aromatic Compounds Be

UNIT 11 ALCOHOLS, PHENOLS & ETHERS

UNIT 11 ALCOHOLS, PHENOLS & ETHERS Alcohols and Phenol are Organic compound with a hydroxyl group (- OH) as functional group. Ethers are identified by a functional group ( 0 ). Cyclic alcohols are named

TOPIC 2. REACTIONS OF AROMATIC COMPOUNDS (Chapters 15, parts of 20, and 21)

L TPIC 2. REACTINS F ARMATIC CMPUNDS (Chapters 15, parts of 20, and 21) Add e.g. of SNAr, replace aniline example, turn BT into and example L TPIC 2. TC PAIN KILLERS BJECTIVES 1. Describe the reactions

Chapter 15 Reactions of Aromatic Compounds

Chapter 15 1 Chapter 15 Reactions of Aromatic Compounds Electrophilic Aromatic Substitution Arene (Ar-H) is the generic term for an aromatic hydrocarbon The aryl group (Ar) is derived by removal of a hydrogen

16. Chemistry of Benzene: Electrophilic Aromatic Substitution جانشینی الکتروندوستی آروماتیک شیمی آلی 2

16. Chemistry of Benzene: Electrophilic Aromatic Substitution جانشینی الکتروندوستی آروماتیک شیمی آلی 2 Dr M. Mehrdad University of Guilan, Department of Chemistry, Rasht, Iran m-mehrdad@guilan.ac.ir Based

16. Chemistry of Benzene: Electrophilic Aromatic Substitution جانشینی الکتروندوستی آروماتیک شیمی آلی 2

16. Chemistry of Benzene: Electrophilic Aromatic Substitution جانشینی الکتروندوستی آروماتیک شیمی آلی 2 Dr M. Mehrdad University of Guilan, Department of Chemistry, Rasht, Iran m-mehrdad@guilan.ac.ir Based

KOT 222 Organic Chemistry II

KOT 222 Organic Chemistry II Course Objectives: 1) To introduce the chemistry of alcohols and ethers. 2) To study the chemistry of functional groups. 3) To learn the chemistry of aromatic compounds and

PAPER No. 5: REACTION MECHANISM MODULE No. 2: Types of Organic Reaction Mechanisms

Subject Chemistry Paper No and Title Module No and Title Module Tag Paper No. 5:Organic Chemistry-II Module No. 2: Overview of different types of Organic Reaction Mechanisms CHE_P5_M2 TABLE OF CONTENTS

Chemistry Questions ans Answers BASED ON HIGH ORDER THINKING SKILL (HOTS) UNIT- 13 ORGANIC COMPOUNDS CONTAINING NITROGEN

Chemistry Questions ans Answers BASED N HIGH RDER THINKING SKILL (HTS) UNIT- 13 RGANIC CMPUNDS CNTAINING NITRGEN 1 MARK QUESTINS Q. 1. Why the presence of a base is essential in the ammonolysis of alkyl

Chapter 17: Alcohols and Phenols

hapter 17: Alcohols and Phenols sp 3 alcohol phenol (aromatic alcohol) pka~ 16-18 pka~ 10 Alcohols contain an group connected to a saturated carbon (sp 3 ) Phenols contain an group connected to a carbon

Benzenes & Aromatic Compounds

Benzenes & Aromatic Compounds 1 Structure of Benzene H H C C C H C 6 H 6 H C C C H H A cyclic conjugate molecule Benzene is a colourless odourless liquid, boiling at 80 o C and melting at 5 o C. It is

NBS, CCl 4 heat A B C D

1. What is(are) the expected product(s) of the following reaction? 2 C=CC( ) 2 NBS, CCl 4 heat A B C D 1) only B 2) only C 3) A and C 4) B and D 2. Which of the following is the 1,4-addition product in

Chapter 17 Reactions of Aromatic Compounds

Chapter 17 Reactions of Aromatic Compounds Electrophilic Aromatic Substitution o General reaction - an electrophile replaces a hydrogen Electrons of pi system attack strong electrophile, generating resonancestabilized

Chemistry of Benzene: Electrophilic Aromatic Substitution

Chemistry of Benzene: Electrophilic Aromatic Substitution Why this Chapter? Continuation of coverage of aromatic compounds in preceding chapter focus shift to understanding reactions Examine relationship

Keynotes in Organic Chemistry

Keynotes in Organic Chemistry Second Edition ANDREW F. PARSONS Department of Chemistry, University of York, UK Wiley Contents Preface xi 1 Structure and bonding 1 1.1 Ionic versus covalent bonds 1 1.2

Topic 3 Alcohols and Ethers

3-1 Topic 3 Alcohols and Ethers 11.1 3-2 Alcohols and Ethers alcohol Examples: ' ether 3C C3 ( )-Menthol Vanillin Anethole (from peppermint) (from vanilla beans) (from fennel) n Poly(phenyl ether) (PPE)

JEFFERSON COLLEGE COURSE SYLLABUS CHM201 ORGANIC CHEMISTRY II. 5 Credit Hours. Prepared by: Richard A. Pierce

JEFFERSON COLLEGE COURSE SYLLABUS CHM201 ORGANIC CHEMISTRY II 5 Credit Hours Prepared by: Richard A. Pierce Revised Date: January 2008 by Ryan H. Groeneman Arts & Science Education Dr. Mindy Selsor, Dean

240 Chem. Aromatic Compounds. Chapter 6

240 Chem Aromatic Compounds Chapter 6 1 The expressing aromatic compounds came to mean benzene and derivatives of benzene. Structure of Benzene: Resonance Description C 6 H 6 1.It contains a six-membered

Ch.17 Alcohols and Phenols

Ch.17 Alcohols and Phenols C An alcohol A phenol An enol - Me: wood alcohol: made from wood - industrial preparation of methanol: C + 2 2 400 o C Zinc oxide/chromia C 3 - Ethanol: fermentation of grains

C h a p t e r N i n e t e e n Aromatics II: Reactions of Benzene & Its Derivatives

C h a p t e r N i n e t e e n Aromatics II: Reactions of Benzene & Its Derivatives Arenium ion from addition of tert-butyl cation to benzene (blue is δ+and red δ-) Note: Problems with italicized numbers

CHAPTER 16 - CHEMISTRY OF BENZENE: ELECTROPHILIC AROMATIC SUBSTITUTION

CAPTR 16 - CMISTRY F BNZN: LCTRPILIC ARMATIC SUBSTITUTIN As stated in the previous chapter, benzene and other aromatic rings do not undergo electrophilic addition reactions of the simple alkenes but rather

Chemistry 204: Benzene and Aromaticity

Chemistry 204: Benzene and Aromaticity Structure of and Bonding in Benzene benzene, C 6 H 6, was first isolated in 1825 (Michael Faraday), but it was not until more than 100 years later that an adequate

Chapter 17. Reactions of Aromatic Compounds

Chapter 17 Reactions of Aromatic Compounds Electrophilic Aromatic Substitution Although benzene s pi electrons are in a stable aromatic system, they are available to attack a strong electrophile to give

Chemistry Chapter 13

Chemistry 2100 Chapter 13 Discovering Aromatics C 6 6 2 C C C C C C 2 3 C C C C C C 3 De war 1867 Ladenburg 1878 C 6 6 Br 2 / Fe (-Br) C 6 5 Br Br 2 / Fe (-Br) C 6 4 Br 2 C 3 C 3 C 2 C 2 C 6 6 1.54 Å 1.33

Lecture 15. Carbonyl Chemistry C B. March 6, Chemistry 328N

Lecture 15 Carbonyl Chemistry - A C B A C + B March 6, 2018 Some loose ends Substitution Reactions Aryl halides do not undergo nucleophilic substitution by either S N 1 or S N 2 pathways! But.. But.this

Chapter 17 Reactions of Aromatic Compounds

rganic Chemistry, 6 th Edition L. G. Wade, Jr. Chapter 17 Reactions of Aromatic Compounds Jo Blackburn Richland College, Dallas, TX Dallas County Community College District 2006, Prentice all Electrophilic

REACTIONS OF AROMATIC COMPOUNDS

A STUDENT SHOULD BE ABLE TO: REACTIONS OF AROMATIC COMPOUNDS 1. Predict the product(s) of Electrophilic aromatic substitution (EAS): halogenation, sulfonation, nitration, Friedel- Crafts alkylation and

CARBOXYLIC ACIDS AND THEIR DERIVATIVES. 3. Predict the relative acidity and basicity of compounds and ions. Important criteria include:

CARBXYLIC ACIDS AND TEIR DERIVATIVES A STUDENT SULD BE ABLE T: 1. Give the IUPAC name given the structure, and draw the structure given the name, of carboxylic acids and their metal salts, acyl chlorides,

Cape Cod Community College

Cape Cod Community College Departmental Syllabus Prepared by the Department of Natural Sciences & Applied Technology Date of Departmental Approval: February 3, 2014 Date Approved by Curriculum and Programs:

Organic Chemistry. M. R. Naimi-Jamal. Faculty of Chemistry Iran University of Science & Technology

Organic Chemistry M. R. Naimi-Jamal Faculty of Chemistry Iran University of Science & Technology Chapter 5-2. Chemistry of Benzene: Electrophilic Aromatic Substitution Based on McMurry s Organic Chemistry,

CHEM Chapter 16. Chemistry of Benzene: Electrophilic Aromatic Substitution (homework) W

CHEM 2425. Chapter 16. Chemistry of Benzene: Electrophilic Aromatic Substitution (homework) W Short Answer Exhibit 16-1 MATCH a structure or term from the following list with each description below. Place

Benzene and Aromatic Compounds. Chapter 15 Organic Chemistry, 8 th Edition John McMurry

Benzene and Aromatic Compounds Chapter 15 Organic Chemistry, 8 th Edition John McMurry 1 Background Benzene (C 6 H 6 ) is the simplest aromatic hydrocarbon (or arene). Four degrees of unsaturation. It

2. Which of the following is NOT an electrophile in an electrophilic aromatic substitution reaction? A) NO 2

Name: CHEM 226 Practice Quiz 3 Chapter 4-Aromatic Compounds and Chapter 7- Alcohols, Phenols and Thiols Attempt all questions showing your answers and work clearly for full and partial credits 1. Which

Chapter 15. Reactions of Aromatic Compounds. Electrophilic Aromatic Substitution on Arenes. The first step is the slow, rate-determining step

Electrophilic Aromatic Substitution on Arenes Chapter 15 Reactions of Aromatic Compounds The characteristic reaction of aromatic rings is substitution initiated by an electrophile halogenation nitration

Carbonyl Chemistry V + C O C. Chemistry /30/02

arbonyl hemistry V Ō - + Keto-enol enol Tautomerism H 3 H 3 Ketone H H R 2 H R' H H 3 H 2 H Enol H Acid atalyzed α Halogenation R 2 R' + X 2 H + R 2 R' + HX H X X 2 can be l 2, Br 2, or I 2. Substitution

Chapter 16. Chemistry of Benzene: Electrophilic Aromatic Substitution. Reactivity of Benzene

hapter 16 hemistry of Benzene: Electrophilic Aromatic Substitution Reactivity of Benzene - stabilization due to aromaticity makes benzene significantly less reactive than isolated alkenes 2 no reaction

REASONING QUESTIONS FROM ORGANIC CHEMISTRY (CH. 1 & 2)

REASONING QUESTIONS FROM ORGANIC CHEMISTRY (CH. 1 & 2) 1.) Why do haloalkenes under go nucleophillic substitution whereas haloarenes under go electophillic substitution. Ans. Due to more electro negative

BENZENE AND AROMATIC COMPOUNDS

BENZENE AND AROMATIC COMPOUNDS The discovery of benzene: 1825 - Michael Faraday, empirical formula of C 1834 - Eilhard Mitscherlich synthesized benzin from gum benzoin, empirical formula C Aromatic The

Chapter 20 Amines-part 2

Reactions of Amines Lone pair on the nitrogen directs the chemistry of amines Chapter 20 Amines-part 2 The nitrogen lone pair can also make a carbon nucleophilic by resonance Amines can also activate carbons

Reactions of Aromatic Compounds. Aromatic compounds do not react like other alkenes. With an appropriate catalyst, however, benzene will react

Reactions of Aromatic Compounds Aromatic compounds do not react like other alkenes 2 Fe 3 2 Does not form A major part of the problem for this reaction is the product has lost all aromatic stabilization,

a. I b. II c. III d. IV e. V

Chemistry 263 Quiz 3 Practice Chapters 18, 22 & 23: Enols, Enolates, Amines and ucleophilic Aromatic Substitution The following practice quiz contains 47 multiple choice questions. Tuesday s quiz will

CHEM 242 REACTIONS OF ARENES: CHAP 12 ASSIGN ELECTROPHILIC AROMATIC SUBSTITUTION A B C D E

CHEM 242 REACTIONS OF ARENES: CHAP 12 ASSIGN ELECTROPHILIC AROMATIC SUBSTITUTION 1. Consider carefully the mechanism of the following electrophilic aromatic substitution reaction and indicate which of

Aromatic Compounds II

2302272 Org Chem II Part I Lecture 2 Aromatic Compounds II Instructor: Dr. Tanatorn Khotavivattana E-mail: tanatorn.k@chula.ac.th Recommended Textbook: Chapter 17 in Organic Chemistry, 8 th Edition, L.

08. Chemistry of Benzene: Electrophilic Aromatic Substitution. Based on McMurry s Organic Chemistry, 6 th edition, Chapter 16

08. Chemistry of Benzene: Electrophilic Aromatic Substitution Based on McMurry s Organic Chemistry, 6 th edition, Chapter 16 Benzene is a nucleophile p electrons make benzene nucleophile, like alkenes.

Lecture 28 Organic Chemistry 1

CEM 232 rganic Chemistry I University of Illinois at ChicagoUIC Lecture 28 rganic Chemistry 1 Professor Duncan Wardrop April 22, 2010 1 Today s Lecture Topics Covered: 1. Aryl alides - Bonding, Physical

September [KV 804] Sub. Code: 3804

September 2009 [KV 804] Sub. Code: 3804 (Regulations 2008-2009) (Candidates admitted from 2008-2009 onwards) Paper IV PHARMACEUTICAL ORGANIC CHEMISTRY Time : Three hours Maximum : 70 marks Answer All questions

Spring Term 2012 Dr. Williams (309 Zurn, ex 2386)

Chemistry 242 Organic Chemistry II Spring Term 2012 Dr. Williams (309 Zurn, ex 2386) Web Page: http://math.mercyhurst.edu/~jwilliams/ jwilliams@mercyhurst.edu (or just visit Department web site and look

CHAPTER 19: CARBONYL COMPOUNDS III

CHAPTER 19: CARBONYL COMPOUNDS III A hydrogen bonded to a carbon adjacent to a carbonyl carbon is sufficiently acidic to be removed by a strong base. The carbon adjacent to a carbonyl carbon is called

H 2 SO 4 Ar-NO 2 + H2O

Phenyl group: Shorthand for phenyl: Ph, C 6 5,. An aryl group is an aromatic group: phenyl, substituted phenyl, or other aromatic group. Shorthand: Ar Generalized electrophilic aromatic substitution: E

Phenols, Ethers, and Organic Sulfur Compound

Phenols, Ethers, and rganic Sulfur Compound Phenols - Structure General Structure - A hydroxy () group attached directly to an aromatic ring: Phenol α-naphthol β-naphthol Note: C2 is not a phenol. Phenols

Chapter 24. Amines. Based on McMurry s Organic Chemistry, 7 th edition

Chapter 24. Amines Based on McMurry s Organic Chemistry, 7 th edition Amines Organic Nitrogen Compounds Organic derivatives of ammonia, NH 3, Nitrogen atom with a lone pair of electrons, making amines

Benzene and Aromatic Compounds

1 Background Benzene and Aromatic Compounds Benzene (C 6 H 6 ) is the simplest aromatic hydrocarbon (or arene). Benzene has four degrees of unsaturation, making it a highly unsaturated hydrocarbon. Whereas

JEFFERSON COLLEGE COURSE SYLLABUS CHM201 ORGANIC CHEMISTRY II. 5 Credit Hours. Prepared by: Richard A. Pierce. Revised by: Sean Birke October, 2013

JEFFERSON COLLEGE COURSE SYLLABUS CHM201 ORGANIC CHEMISTRY II 5 Credit Hours Prepared by: Richard A. Pierce Revised by: Sean Birke October, 2013 Ms. Linda Abernathy, Math, Science & Business Division Chair

Solution problem 22: Non-Benzoid Aromatic Sytems

Solution problem 22: on-enzoid Aromatic Sytems 22.1 & 22.2 Each double bond and each heteroatom (, ) with lone pairs donates 2 π- electrons as well as a negative charge. oron or a positive charge does

The now-banned diet drug fen-phen is a mixture of two synthetic substituted benzene: fenfluramine and phentermine.

The now-banned diet drug fen-phen is a mixture of two synthetic substituted benzene: fenfluramine and phentermine. Chemists have synthesized compounds with structures similar to adrenaline, producing amphetamine.

Chapter 4: Aromatic Compounds. Bitter almonds are the source of the aromatic compound benzaldehyde

Chapter 4: Aromatic Compounds Bitter almonds are the source of the aromatic compound benzaldehyde Sources of Benzene Benzene, C 6 H 6, is the parent hydrocarbon of the especially stable compounds known

Organic Chemistry II KEY March 27, Which of the following reaction intermediates will form the fastest in the reaction below?

rganic Chemistry II KEY March 27, 2013 Exam 2: VERSI D 1. Which of the following reaction intermediates will form the fastest in the reaction below? C 1 equiv a 2 a) IV b) III c) II d) II & III e) I I.

Chapter 5. Aromatic Compounds

Chapter 5. Aromatic Compounds 5.1 Structure of Benzene: The Kekule Proposal Mid-1800s, benzene was known to have the molecular formula C 6 6. Benzene reacts with 2 in the presence of iron to give substitution

Chapter 15. Reactions of Aromatic Compounds. 1. Electrophilic Aromatic Substitution Reactions

hapter 15 eactions of Aromatic ompounds 1. Electrophilic Aromatic Substitution eactions v verall reaction reated by Professor William Tam & Dr. Phillis hang opyright S 3 2 S 4 S 3 2. A General Mechanism

BENZENE & AROMATIC COMPOUNDS

BENZENE & AROMATIC COMPOUNDS Dr. Zainab M Almarhoon 2 Learning Objectives By the end of chapter four the students will: Understand the resonance description of structure of benzene Understand the hybridization

Module9. Nuclear Magnetic Resonance Spectroscopy Nuclear Magnetic Resonance (NMR) spectroscopy - Chemical shift - Integration of signal area

1 CHEMISTRY 263 HOME WORK Lecture Topics: Module7. Hydrogenation of Alkenes The Function of the Catalyst - Syn and anti- addition Hydrogenation of Alkynes - Syn- addition of hydrogen: Synthesis of cis-alkenes

Benzylamine reacts with nitrous acid to form unstable diazonium salt, which in turn gives alcohol with the evolution of nitrogen gas.

Benzylamine reacts with nitrous acid to form unstable diazonium salt, which in turn gives alcohol with the evolution of nitrogen gas. On the other hand, aniline reacts with HNO2 at a low temperature to

Reaction of Benzene and its Derivatives 22-1

Reaction of Benzene and its Derivatives 22-1 Reactions of Benzene Substitution at a ring carbon. alogenation: 2 Fe 3 Chlorobenzene Contrast to radical mechanism for benzylic hyrdogens Nitration: 2 S 4

CHEMISTRY 263 HOME WORK

Lecture Topics: CHEMISTRY 263 HOME WORK Module7: Hydrogenation of Alkenes Hydrogenation - syn and anti- addition - hydrogenation of alkynes - synthesis of cis-alkenes -synthesis of trans-alkenes Text sections:

More Nomenclature: Common Names for Selected Aromatic Groups. Aryl = Ar = aromatic group. It is a broad term, and includes any aromatic rings.

More Nomenclature: Common Names for Selected Aromatic Groups Phenyl group = or Ph = C 6 H 5 = Aryl = Ar = aromatic group. It is a broad term, and includes any aromatic rings. Benzyl = Bn = It has a -CH

Unit 13-NITROGEN CONTAINING ORGANIC COMPOUNDS

Unit 13-NITROGEN CONTAINING ORGANIC COMPOUNDS Two marks: 1. Name the product obtained when a nitrile is reduced by H 2 /Ni,. Give the equation. H 2 /Ni, Primary amine: RCN RCH 2 NH 2. 2. How is nitrobenzene

CHAPTER PRACTICE PROBLEMS CHEMISTRY

APTER PRACTICE PRBLEMS EMISTRY Electrophilic Aromatic Substitution Name : Batch : Date : rientation influence of groups 1. Predict the characteristics of -NH + as a substituent. activating, o/p directing

Organic Chemistry. Second Edition. Chapter 19 Aromatic Substitution Reactions. David Klein. Klein, Organic Chemistry 2e

Organic Chemistry Second Edition David Klein Chapter 19 Aromatic Substitution Reactions Copyright 2015 John Wiley & Sons, Inc. All rights reserved. Klein, Organic Chemistry 2e 19.1 Introduction to Electrophilic

Question 13.1: Classify the following amines as primary, secondary or tertiary: (i) (ii) (iii) (C 2 H 5 ) 2 CHNH 2 (iv) (C 2 H 5 ) 2 NH Primary: (i) and (iii) Secondary: (iv) Tertiary: (ii) Question 13.2:

4 - BENZENE: AROMATICITY, CONJUGATION AND ASSOCIATED REACTIVITY

4 - BENZENE: AROMATICITY, CONJUGATION AND ASSOCIATED REACTIVITY During the early 1800's, a group of compounds of natural origin became collectively known as aromatic compounds. As several of these compounds

235 Organic II. Final Exam Review REACTIONS OF CONJUGATED DIENES 1,2 VS 1,4 ADDITION REACTIONS OF CONJUGATED DIENES

b. the ompound 7 i 1 Spectral Data: singlet, 196.5 ppm singlet, 14.1 ppm singlet, 14.4 ppm doublet, 19.1 ppm doublet, 18.5 ppm 1 MR Mass Spectrum Absorbance Intensity Infrared Spectrum 65 91 9. Structure:

Learning Guide for Chapter 14 - Alcohols (I)

Learning Guide for Chapter 14 - Alcohols (I) I. Introduction to Alcohols and Thiols II. Acid/base Behavior of Alcohols, Phenols, and Thiols III. Nomenclature of Alcohols IV. Synthesis of Alcohols Previous

2016 Pearson Education, Inc. Isolated and Conjugated Dienes

2016 Pearson Education, Inc. Isolated and Conjugated Dienes 2016 Pearson Education, Inc. Reactions of Isolated Dienes 2016 Pearson Education, Inc. The Mechanism Double Bonds can have Different Reactivities

Chapter 19. Organic Chemistry. Carbonyl Compounds III. Reactions at the a-carbon. 4 th Edition Paula Yurkanis Bruice

Organic Chemistry 4 th Edition Paula Yurkanis Bruice Chapter 19 Carbonyl Compounds III Reactions at the a-carbon Disampaikan oleh: Dr. Sri Handayani 2013 Irene Lee Case Western Reserve University Cleveland,

Chapter 16: Ethers, Epoxides, and Sulfides

Chapter 16: Ethers, Epoxides, and Sulfides 16.1: omenclature of Ethers, Epoxides, and Sulfides (Please read) 16.2: Structure and Bonding in Ethers and Epoxides The ether oxygen is sp 3 -hybridized and

Alcohols, Ethers and Epoxides. Chapter Organic Chemistry, 8th Edition John McMurry

Alcohols, Ethers and Epoxides Chapter 17-18 Organic Chemistry, 8th Edition John McMurry 1 Introduction Structure and Bonding Alcohols contain a hydroxy group (OH) bonded to an sp 3 hybridized carbon. 2

Class XII Chapter 11 Alcohols Phenols and Ethers Chemistry. Question 11.1: Write IUPAC names of the following compounds: (i) (ii) (iii) (iv) (v) (vi)

Question 11.1: Write IUPAC names of the following compounds: (iii) (iv) (v) (vi) (vii) (viii) Page 1 of 37 (ix) (x) (xi) (xii) 2, 2, 4-Trimethylpentan-3-ol 5-Ethylheptane-2, 4-diol (iii) Butane-2, 3-diol

Treatment of cyclooctatetrene with potassium gives you a dianion. Classify the starting material and product as aromatic, antiaromatic or

Treatment of cyclooctatetrene with potassium gives you a dianion. Classify the starting material and product as aromatic, antiaromatic or nonaromatic? 1 2 Classify cyclononatetrene and it s various ions

CARBOXYLIC ACIDS AND THEIR DERIVATIVES

ARBXYLI AIDS AND TEIR DERIVATIVES A STUDENT SULD BE ABLE T: 1. Give the IUPA name given the structure, and draw the structure given the name, of carboxylic acids and their metal salts, acyl chlorides,

SYSTEMWIDE CHEM 2425 FINAL EXAM. Department Of Physical Sciences

SYSTEMWIDE CHEM 2425 FINAL EXAM Department f Physical Sciences Morphine NAME: RGANIC CHEM 2425 FINAL EXAM DIRECTINS- A periodic table is attached at the end of this exam. Please answer all questions in