Curriculum Vitae. Tata Gopinath

Transcription

1 6-155 Jackson Hall, 321 Church St SE Department of Biochemistry, Molecular Biology, & Biophysics Minnesota NMR Center Minneapolis, MN 55455, USA Education Curriculum Vitae 1999 B.Sc., SR&BGNR College, Khammam, Andhra Pradesh, India 2001 M.Sc., Hyderabad Central University, Hyderabad, Andhra Pradesh, India 2007 Ph.D., Physics Department and NMR Research Center, Indian Institute of Science, Bangalore, Karnataka, India Scientific Employment Lecturer, Shaadan Post Graduate College, Hyderabad, India Postdoctoral Associate, Biochemistry, Molecular Biology and Biophysics (BMBB), Research Associate, BMBB, 2012-present Research Assistant Professor, BMBB and Minnesota NMR center, Fellowships and honors Publications 2012 Technical innovation award from College of Biological Sciences,, for developing novel ground breaking solid state NMR methods for Biomolecules Winner of Paul D. Boyer James B. Peter Award for significant research contributions in biophysics as a postdoctoral associate Cyrus P. Barnum and Anne R. Barnum Postdoctoral Travel Award, from BMBB Department, GATE-2002 (Graduate Aptitude Test of Engineering in Physics) with All India Rank Indian Institute of Science (IISc) fellowship Recipient of CSIR-NET Lecturer-ship conducted by conducted by Council of Scientific and Industrial Research, India Selected participant of Indian Institute of Astrophysics summer school. 34. Gopinath T, Nelson S E, Soller K J, Veglia G (2017) Probing the Conformationally Excited States of Membrane Proteins via 1H-Detected MAS Solid-State NMR Spectroscopy, J Phys Chem B, 121, Gopinath T, Nelson S E, Veglia G (2017) 1 H-detected MAS Solid-State NMR Experiments Enable the Simultaneous Mapping of Rigid and Dynamic Domains of Membrane Proteins solid-state NMR Spectroscopy (submitted). 32. Gopinath T, Veglia G (2017) Experimental aspects of Polarization Optimized Experiments (POE) for Magic Angle Spinning Solid-State NMR of Micro-crystalline and Membrane-Bound Proteins (submitted). 1

2 31. Gopinath T, Veglia G (2016), Orphan spin polarization: A catalyst for high-throughput solid-state NMR, Annual reports on NMR Spectroscopy), 89, Dicke A, Gopinath T, Veglia G (2016) Probing Residue-Specific Water-Protein Interactions in Oriented Lipid Membranes via Solid-State NMR Spectroscopy Distance measurements from Separated Local Field Experiments. J Phys Chem B, 120, Gopinath T, Veglia G (2016), Multiple acquisitions via sequential transfer of orphan spin polarization (MAeSTOSO): How far can we push residual spin polarization in solid-state NMR?, J Magn Reson, 267, Vostrikov V, Gustavsson M, Gopinath T, Mullen D, Dicke A, Truong V, Veglia G (2016), Ca2+ ATPase conformational transitions in lipid bilayers mapped by site-directed ethylation and solid-state NMR. ACS Chem. Biol. 11, Gopinath T, Veglia G (2015), Multiple acquisition of magic angle spinning solid-state NMR experiments using one receiver: application to microcrystalline and membrane proteins, special issue of J. Magn. Reson. 253, Gopinath T, Mote KR, Veglia G (2015), Simultaneous acquisition of oriented solid state NMR experiments: Towards sequential assignment of membrane proteins, J. Biomol. NMR 62, Mistry P, Mohapatra S, Gopinath T, Vogt FG, Suryanarayanan R (2015), Role of the strength of drug-polymer interactions on the molecular mobility and physical stability of amorphous solid dispersions Molecular Pharmaceutics 12, Vostrikov V, Soller K, Ha K, Gopinath T, Veglia G (2015), Effects of naturally occurring arginine 14 deletion on phospholamban conformational dynamics and membrane interactions. Biochim. Biophys. Acta 1848, Cheryl C,Verardi R, Severini C, Bottegoni G, Rocchia W, BrownP, Gopinath T, Vostrikov V, Razzoli M, Gurney A, Sassano MF, Roth BL, Piomelli D, Vulchanova L, Possenti R, Veglia G, Bartolomucci A (2014), The TLQP-21 Peptide Activates the G-Protein-Coupled Receptor C3aR1 via a Folding-upon-Binding Mechanism, Structure 22, Fusco G, De Simone A, Gopinath T, Vostrikov V, Vendruscolo M, Dobson CM, Veglia G (2014) Direct observation of the three regions in α-synuclein that determine its membrane-bound behavior, Nature Communications 5, Gopinath T, Mote KR, Veglia G (2013) Sensitivity and Resolution Enhancement of Oriented Solid-State NMR: Application to Membrane Proteins. Progress in Nuclear Magnetic Resonance Spectroscopy 75, Gustavsson M, Verardi R, Mullen DG, Mote KR, Traaseth NJ, Gopinath T, Veglia G (2013) Allosteric regulation of SERCA by phosphorylation-mediated conformational shift of phospholamban. Proc Natl Acad Sci 106, Mote KR, Gopinath T, Veglia G (2013) Determination of structural topology of a membrane protein in lipid bilayers using polarization optimized experiments (POE) for static and MAS solid state NMR spectroscopy. J Biomol NMR, 57, Gopinath T, Veglia G (2013) Orphan spin operators enable the acquisition of multiple 2D and 3D magic angle spinning solid-state NMR spectra. J Chem Phys, 138, Gopinath T, Veglia G (2012) 3D DUMAS: Simultaneous acquisition of three dimensional Magic Angle Spinning solid state NMR experiments of Proteins. J Magn Reson, 220, Gopinath T, Veglia G (2012) Dual Acquisition Magic-Angle Spinning Solid-State NMR- Spectroscopy: Simultaneous Acquisition of Multidimensional Spectra of Biomacromolecules. Angew Chem Int Ed, 51, Veglia G, Traaseth NJ, Shi L, Verardi R, Gopinath T, Gustavsson M (2012) The Hybrid Solution/Solid- State NMR Method for Membrane Protein Structure Determination. Comprehensive Biophysics, doi: /B

3 14. Gopinath T, Mote KR, Veglia G (2011) Proton Evolved Local Field solid-state Nuclear Magnetic Resonance using Hadamard encoding: Theory and Application to Membrane Proteins. J Chem Phys 135, 7, Mote KR, Gopinath T, Veglia G (2011) Multi-dimensional oriented solid-state NMR experiments enable the sequential assignment of uniformly 15N labeled integral membrane proteins in magnetically aligned lipid bilayers. J Biomol NMR, 51, 3, Gopinath T, Veglia G (2010) Improved resolution in dipolar NMR spectra using constant time evolution PISEMA Experiment. Chemical Physics Letters 494, Traaseth NJ, Gopinath T, Veglia G (2010) On the Performance of Spin Diffusion NMR Techniques in Oriented Solids: Prospects for Resonance Assignments and Distance measurements from Separated Local Field Experiments. J Phys Chem B, 114, Gopinath T, Verardi R, Traaseth NJ, Veglia G (2010) Sensitivity enhancement of separated local field experiments: application to membrane proteins. J Phys Chem B, 114, Gopinath T, Traaseth NJ, Mote KR, Veglia G (2010) Sensitivity Enhanced Heteronuclear Correlation Spectroscopy in Multidimensional Solid-State NMR of Oriented Systems via Chemical Shift Coherences. J Am Chem Soc, 132, Gopinath T, Veglia G (2009) Sensitivity Enhancement in Static Solid-State NMR Experiments via Single and Multiple-Quantum Dipolar Coherences. J Am Chem Soc, 131, Gopinath T, Kumar A (2009) Implementation of Liouville Space Search Algorithm on a strongly dipolar Coupled Nuclear Spins. Future Directions of Magnetic Resonance" Special issue to commemorate the Platinum Jubilee of the Indian National Science Academy, Springer. 6. Gopinath T, Kumar A (2008) Implementation of Collins version of Deutsch-Jozsa algorithm on quadrupolar spin-7/2 nucleus using non-adiabatic geometric phases. J Magn Reson, 193, Ghosh A, Das R, Gopinath T, Kumar A (2006) Use of Geometric Phase in Quantum information Processing by Nuclear Magnetic Resonance. Proceedings of Workshop on 'Quantum Information, Computation and Communication' (QICC-2005), Eds. S.P. Pal and S. Kumar, Allied Publishers, India, pages (2006). 4. Gopinath T, Kumar A (2006) Hadamard NMR spectroscopy for two-dimensional quantum information processing and parallel search algorithms. J Magn Reson, 183, Gopinath T, Kumar A (2006) Geometric quantum computation using fictitious spin- 1/2 subspaces of strongly dipolar coupled nuclear spins. Physical Review A, 73, Gopinath T, Das R, Kumar A (2005) Programmable quantum state discriminator by nuclear magnetic resonance. Physical Review A, 71, Gopinath T, Das R, Kumar A (2004) Quantum information processing by NMR: Implementation of Inversion-on-equality gate, Parity gate and Fanout gate. Proc. Indian Natn. Sci. Acad., 70 A, ( Oral presentations 12. Multiple Acquisitions of Magic Angle Spinning Solid-State NMR Experiments Using One Receiver: Application to Microcrystalline and Membrane Proteins, Experimental Nuclear Magnetic Resonance Conference, Pittsburgh, Pennsylvania, April 10-15, Multiple Acquisitions of Magic Angle Spinning Solid-State NMR Experiments Using One Receiver: Application to Microcrystalline and Membrane Proteins, Chicago Area NMR Discussion Group, Northwestern U., Evanston, Illinois. 10. Fast multi-dimensional solid-state NMR experiments for membrane protein structure determination. NMR meets biology: Discussion meeting on NMR and challenging biology issues, Goa, India, February 21-27, Solid-State NMR methods: Application to polymer science. Food Science and Nutrition Department,, December 20,

4 8. Dual acquisition magic angle spinning solid-state NMR: A new approach to high-throughput structure determination of proteins. Symposium on Atomic View of Bimolecular Function, University of Michigan, Ann Arbor, July 11-14, Lectures on NMR spectroscopy for protein structure determination. Hands-On Protein NMR workshop, Minnesota NMR Center,, June 3-7, Methodological developments in solid state NMR of biomacromolecules. Solid State NMR Symposium at Rocky Mountain Conference on Analytical Chemistry, Copper Conference Center in Copper Mountain, Colorado, July 15-19, Dual acquisition MAS solid-state NMR experiments. The 14th Bollum Symposium, University of Minnesota, May 23, Dual Acquisition Magic Angle Spinning (DUMAS) Solid-State NMR: A new approach to simultaneous acquisition of multi-dimensional spectra of Biomacromolecules. Experimental Nuclear Magnetic Resonance Conference, Miami, Florida, April 15-20, Methodological developments in solid state NMR: Application to membrane proteins. Boyer-Peter Award seminar,, September 21, Quantum Computing and Quantum Information Processing By Nuclear Magnetic Resonance. Ph.D Thesis Dissertation. Indian Institute of Science, July Critical current in Superconductivity. M. Sc. Project, June Poster presentations 11. Orphan Spin Operators Enable the Acquisition of Multiple 2D and 3D MAS Solid-State NMR Spectra. Gopinath T, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, California, March Dual Acquisition Magic Angle Spinning (DUMAS) Solid-State NMR. Gopinath T, Veglia G. Symposium on Atomic View of Bimolecular Function, University of Michigan, Ann Arbor, July 11-14, Oriented Solid-State NMR reveals topological changes of Sarcolipin in complex with the Sarcoplasmic Reticulum Ca2+-ATPase. Mote KR, Vostrikov VV, Gopinath T, Veglia G. Symposium on Atomic View of Bimolecular Function, University of Michigan, Ann Arbor, July 11-14, Sensitivity Enhancement of 13C-15N HETCOR Experiments in Static Solid-State NMR. Gopinath T, Hung I, Mote KR, Gor kov PL, Gan Z, Veglia G. National High Magnetic Field Laboratory, Tallahassee, Florida, MAGLAB research report Membrane Protein Structure and Topology in Supported Lipid Bilayers and Bicelles using Multidimensional Oriented and MAS Solid State NMR Spectroscopy. Mote KR, Gopinath T, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Miami, Florida, April Proton evolved local field solid state NMR using Hadamard encoding. Gopinath T, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, California, March Sensitivity enhancement in solid state NMR of aligned membrane proteins. Gopinath T, Traaseth NJ, Verardi R, Mote KR, Veglia G. Experimental Nuclear Magnetic Resonance Conference, Daytona Beach, Florida, April, Liouville Space Search Algorithm: Experimental Implementation in Strongly Coupled Spins. Gopinath T, Kumar A. Experimental Nuclear Magnetic Resonance Conference, Daytona Beach, Florida, April, Hadamard NMR spectroscopy for two-dimensional quantum information processing and parallel search algorithms. Gopinath T, Kumar A. National magnetic resonance society (NMRS) conference, Pune, India, February Programmable Hadamard Encoding for Parallel Search, Preparation of Pseudo-Pure States and Two- Dimensional Quantum Gates and Algorithms. Kumar A, Gopinath T. Experimental Nuclear Magnetic Resonance Conference, Pacific Grove, California, April, Programmable quantum state discriminator using nuclear magnetic resonance. Gopinath T, Das R, Kumar A. International conference on magnetic resonance in Biological systems (ICMRBS), Hyderabad, India, February

5 1. Quantum information processing by NMR: Implementation of Inversion-on-equality gate, Parity gate and Fanout gate. Gopinath T, Das R, Kumar A. National magnetic resonance society (NMRS) conference, Kolkatta, India, February