Prof. Kishwar Saleem Professor (Organic Chemistry)

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1 Prof. Kishwar Saleem Professor (Organic Chemistry) Department of Chemistry Faculty of Natural Sciences Jamia Millia Islamia (Central University) New Delhi (India) Telephone: Extn (Lab.) Mobile: Date of Birth: 11 th -July-1948 Date of Joining Service JMI: February 1973 Research Areas: In spite of good advancements for diagnosis and treatment, cancer is still a big threat to our society. This is the second most common disease after cardiovascular disorders for maximum deaths in the world. It accounts for about 23 and 7% deaths in USA and India, respectively. The world s population is expected to rise to 7.5 billion by 2020 and approximations predict that about 15.0 million new cancer cases will be diagnosed; with deaths of about 12.0 million cancer patients. The prevalence of cancer in India is estimated to be around 2.5 million, with about 8, 00,000 new cases and 5, 50,000 deaths per annum. According to 1991 Indian census data, about cancer cases have been observed. This number had drastically increased to 806,000 by the end of the last century; with 96.4 and 88.2% age standardized rates for males and females; out of 100,000 cases analyzed. Among some cancer treatment strategies, chemotherapy is gaining importance continuously. Some medications are in market while few under clinical trials. But, unfortunately, no one is complete medication with leas or no side effects. During last few decades, metal ion complexes have gained importance as anticancer drugs. In view of these facts, research is in progress for developing novel metal ion complexes for treating different cancers. Besides, efforts are being made in the direction for developing novel methods of Chromatography for the separation and identification of simple and chiral drugs and xenobiotics.

2 A Cancerous Tissue NAMI-A: Ruthenium Based Anticancer Agent Academic Qualifications: S. No. Degree Year University 1. M.Sc Aligarh Muslim University, Aligarh India. 2. Ph.D Aligarh Muslim University, Aligarh, India. PhD Thesis Title: Synthesis and Characterisation of Modified Steroids with special reference to Sterol Employment Profile: S.No. Position Held From To Department/Name of Institutes 1. Lecturer Feb 1973 Jan 1983 Department of Chemistry, JMI, New Delhi Reader Jan 1983 Mar 2003 Department of Chemistry, JMI, New Delhi Professor Mar 2003 Till date Department of Chemistry, JMI, New Delhi

3 Course Taught at PG and UG Level (1) Organic Chemistry, Natural Products Chemistry, General Chemistry. (2) Lab courses for M.Sc. Organic (Previous and Final) and B.Sc. (H) Chemistry, B.Sc. (Subsidiary), and Others. Self-Project Work: S. No. Name of Project Position Awarded by 1. Synthesis and characterization Principal UGC of Thiosemi Investigator carbazones and triazoli dines 2. Ni(II), Pd(II) and Pt(II) Complexes of Azole based Ligands: potential Anticancer Agents Principal Investigator UGC Duration Amount (Lakhs) 12,000 1,20,000 Administrative and University Responsibilities: (i) Ex-Head ( ), Department of Chemistry, Jamia Millia Islamia, New Delhi (ii) V.C. Nominee of Girls Hostel. (iii) Superintendent, Faculty of Natural sciences Final Examination ( ). (iv) Nominee of Major Project Evaluation by UGC ( ). Supervision of Ph.D. No. Ph.D. Awarded 08 No. Ph.D. Students under supervision 02 No. Ph.D. Students under co-supervision. 00 Title of the Thesis of Earlier Ph.D. Scholars: 1. Abdul Roouf Bhat: Synthesis, Structure Activity Relationship and Biological Screening of Some Heterocyclic Compounds. 2. Ajay Singh: Design, Synthesis, Characterisation and Biological activities of some new compounds.

4 3. Afzal Hussain: Evaluation of Chromatographic Methods for Analyses of Simple and Chiral Drugs in Human Plasma.(Co-Supervisor) 4. Iqbal Hussain: Development of Liquid Chromatographic Methods of Simple and Chiral Drugs Monitoring in Biological Samples.(Co-Supervisor) 5. Kamlesh Sharma: Synthesis of Hetero cyclic Organic Compounds with Special Reference to Steroids. 6. Mohammad Ilyas: Kinetics of Oxidative Degradation of the Bio-molecules. 7. Neha Singh: Designing, Synthesis and Biological Evaluation of some Heterocyclic Compounds. (Co-Supervisor) 8. Salman Ahmad Khan: Synthesis and Mechanistic Studies of Nitrogen, Oxygen and Sulphur Containing Organic Compounds. 9. Shuchi Verma: Study on the bio-diesel preparation from non-edible vegetable oil. 10. Sonali Rudra: Design, Synthesis and Biological Evaluation of Novel Bio-active Molecules. Current Research Scholar: Ashanul Haque: Isolation, Characterization and Application of Anticancer Compounds from Medicinal Plants. (Nov Onwards). Wasem Ahmed Wani: Synthesis, Characterization and Anticancer Profiles of Glutamides and their Metal Complexes. (Nov Onwards). Publications: 1. Ali I., Rahisuddin, Saleem K., Rather M.A., Wani W.A., Haque A. Current Cancer Drug Targets, 11, (2011). 2. Ali I., Rahisuddin, Saleem K., Aboul-Enein, H.Y., Rather A. Cancer Therapy, 8, 6-14 (2011). 3. Ali I., Saleem K., Uddin R., Haque A., El-Azzouni A., Egypt. Pharm. J. (NRC), 9(2), (2010). 4. Ali I., Saleem K. and Aboul-Enein H.Y., Comb. Chem. & High Through. Screen. 13, , (2010). 5. Gupta K., Singh V.P., Kurupati R.K., Mann A., Ganguli M., Gupta YK., Singh Y., Saleem K., Pasha S., Maiti S., J. Con. Rel Feb 20;134(1): Ali I., Saleem K., Gaitonde V.D., Aboul-Enein H.Y., Hussain I., Chirality. 22, 24-28, 2010.

5 7. Khan S.A., Singh N. and Saleem K., Eur J Med Chem Oct;43 (10): Khan S.A., Saleem K., Khan Z., Eur J Med Chem.2008 Oct;43(10): Khan S.A., Kumar P., Joshi R., Iqbal PF., Saleem K., Eur J Med Chem Sep;43(9): Ali I., Hussain I., Saleem K., Aboul-Enein HY., Bazylak G., Curr Drug Discov Technol Jun;5(2): Gupta K., Vats I.D., Gupta Y.K., Saleem K., Peptides Dec;29(12): Khan S.A, Saleem K., Khan Z., Eur. J. Med. Chem. 42(1) B, , (2007). 13. Khan S.A, Saleem K., Khan Z., Colloids & Surface A: Physico-chemical and Engg. Aspects, 302(1-3), , (2007). 14. Khan S.A., Saleem K., Khan Z., Eur. J. Med. Chem Sharma K., Saleem K., Saleem A. Ind. J. Chem. 45 B, , (2006). 16. Sharma K., Saleem K., Saleem A. Ind. J. Chem. 42 B, , (2003). 17. Shamsuzzama, Saleem A., Akram M.K., Saleem K., Siddiqui N., Ind. J. Chem., 42 B, , (2003). 18. Bharti N., Shailendra, Gaza M.T.G., Saleem K., Naqvi F., Maurya M.R., Azam A. Bioorg. and Med. Chem. Lett. 12, , (2002). 19. Sharma K., Saleem K., Saleem A. Ind. J. Chem. VI B, , (2002). 20. Shailendra, Bharti N., Gaza M.T.G, Cruz-vega D.E, Saleem K., Naqvi F. Azam A. Bioorg. and Med. Chem. Lett. 11, , (2001). 21. Shamsuzzaman, Saleem A., Saleem K., and Khan M.A. Ind. J. Chem. 36 B, , (1997). 22. Ahmad M.S., Mushfiq M., Saleem K., Alam Z., Iqbal N., Ind. J. Chem. 27B, (1988). 23. Ahmad M.S., Ansari I.A., Saleem K., and Moinuddin G. Ind. J. Chem. 2313, , (1984). 24. I. Ali, K. Saleem and A. Haque, International Conference on Chemistry Frontiers and Challenges-2011, Department of Chemistry, Aligarh Muslim University, Aligarh (U.P), India. 25. I. Ali, K. Saleem and W.A. Wani, International Conference on Chemistry Frontiers and Challenges-2011, Department of Chemistry, Aligarh Muslim University, Aligarh (U.P), India. 26. I. Ali, K. Saleem and M.A. Rather, International Conference on Chemistry Frontiers and Challenges-2011, Department of Chemistry, Aligarh Muslim University, Aligarh (U.P), India 27. I. Ali, K. Saleem, W.A. Wani and A. Haque, Recent Advances in Chemistry- 2011, Department of Chemistry, Jamia Millia Islamia, New Delhi

6 28. I. Ali, K. Saleem, A. Haque, S.D. Alam, Recent Aspects of Research in Applied Science (RRAS-2011), Department of Applied Sciences, Inderprastha Engineering College, Ghaziabad (U.P) India. 29. I. Ali, K. Saleem, A. Haque and W.A. Wani, Recent Advances in Chemistry- 2011, Department of Chemistry, Jamia Millia Islamia, New Delhi I.Ali, K. Saleem, A.K. Rajora, M.A. Rather, A. Haque, Recent Advances in Chemistry-2010, Department of Chemistry Jamia Millia Islamia, New Delhi Conference/Workshop Attended 1. National Symposium New Vistas in chemical Society in Hyderabad Mar (1995) th Indian Council of Chemists in Chennai. Nov (1998). 3. Workshop on Nano materials Department of Physics Jamia Millia Islamia, New- Delhi Nov 1 (2002). 4. Workshop on Chromatographic techniques Department of Chemistry Jamia Millia Islamia, New-Delhi Sept 10 (2007). 5. Attended users meeting sophisticated analytical instrument facility CDRI Lucknow Sept 27 (2007). 6. Seminar on synthesis and characterization of nanomaterials, Jamia Humdard New-Delhi Nov 17 (2007). 7. Interdisciplinary Science Conference on Recent Trends in Research in Biological Sciences ISC 2007 Jamia Millia Islamia, New-Delhi Dec 7 (2007). 8. An International Conference on Chemistry Frontiers and Challenges, at Department of Chemistry, A.M.U., Aligarh held on 5-6 th March, Climate Change and Environment at Al-Flah School of Engineering and Technology, Dhauj, Faridabad held on April 22, National Seminar on Role of GCMS, Flash Chromatography and HPLC in Botanical Drug Development at Jamia Hamdard, New Delhi held on January 17, An International Conference on Chemistry Frontiers and Challenges, at Department of Chemistry, A.M.U., Aligarh held on 5-6 th March, Climate Change and Environment at Al-Flah School of Engineering and

7 Technology, Dhauj, Faridabad held on April 22, A lecture on Opportunity to do Graduate Studies in Chemistry at the National University of Singapore at Department of Chemistry, Jamia Millia Islamia, New Delhi held on February 24, Natural Science INFO-Fest-2008 organized by Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi during March 04-06, One day seminar on Recent Advances in Chemistry (RAC-08) under UGC- DRS project at Jamia Millia Islamia, New Delhi held on March 28, Conference Organized: 1. One day seminar on Recent Advances in Chemistry (RAC-11) under UGC- DRS project held in Jamia Millia Islamia, on Reviewer of the Some Peer reviewed Journals Like: European Journal of Medicinal Chemistry. Indian Journal of chemistry Bio-Organic and Medicinal Chemistry Saudi Arabian Journal of Chemistry

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