CropLife Australia Insecticide Resistance Management Review Group Mode of Action Classification for Insecticides Valid as at 7 June 2017

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1 1* Acetylcholinesterase inhibitors * all members of this class may not be cross resistant 2 GABA-gated chloride channel blockers 1A Carbamates* 1B Organophosphates* 2A Cyclodiene organochlorines 2B Phenylpyrazoles (Fiproles) Bendiocarb Carbaryl Carbofuran Carbosulfan Methiocarb Methomyl Oxamyl Pirimicarb Propoxur Thiodicarb Acephate Azamethiphos Azinphos methyl Cadusafos Chlorfenvinphos Chlorpyrifos Chlorpyrifos-methyl Diazinon Dichlorvos Dimethoate Ethion Fenamiphos Fenitrothion Fenthion Maldison (malathion) Methidathion Mevinphos Omethoate Phorate Phosmet Pirimiphos-methyl Profenofos Prothiofos Temephos Terbufos Trichlorfon No registered actives Fipronil 1 Refer APVMA website ( to obtain complete list of registered products from the PUBCRIS database This document is a guide only and does not endorse particular products, groups of products or cultural methods in terms of their performance. Always follow the product label for specific use instructions. While all effort has been taken with the information supplied in this document no responsibility, actual or implied, is taken for the day to day accuracy of product or active constituent specific information. Readers should check with the Australian regulator s (APVMA) product database for contemporary information on products and actives. The database can be sourced through The information given in this document is provided in good faith and without any CropLife Australia Limited, Locked Bag 4396, Canberra ACT 2604 Page 1 of 7

2 3 Sodium channel modulators 4 Nicotinic acetylcholine receptor (nachr) competitive modulators 5 Nicotinic Acetylcholine receptor allosteric modulators (nachr) 6 Glutamate-gated Chloride (GluCl) channel allosteric modulators 7 Juvenile hormone mimics 3A Pyrethroids Pyrethrins 3B 4A Neonicotinoids 4B Nicotine 4C Sulfoximine Spinosyns Avermectins Milbemycins 7A Juvenile hormone analogues 7B Fenoxycarb 7C Pyriproxyfen Allethrin Alpha-cypermethrin Beta-cyfluthrin Bifenthrin Bioallethrin Bioresmethrin Cyfluthrin Cypermethrin Cyphenothrin Deltamethrin Esbiothrin Esfenvalerate Fenvalerate Flumethrin Gamma-cyhalothrin Imiprothrin Lambda-cyhalothrin Permethrin Prallethrin Pyrethrins Tau-fluvalinate Tetramethrin Transfluthrin Zeta-cypermethrin Acetamiprid Clothianidin Dinotefuran Imidacloprid Thiacloprid Thiamethoxam Sulfoxaflor Spinosad Spinetoram Abamectin, Emamectin benzoate Milbemectin Methoprene Fenoxycarb Pyriproxyfen Page 2 of 7

3 8 Miscellaneous non-specific (multisite) inhibitors- 9 Chordotonal organ TRPV channel modulators Nerve Action 10 Mite growth inhibitors 11 Microbial disrupters of insect midgut membranes (includes transgenic crops expressing Bacillus thuringiensis toxins) 12 Inhibitors of mitochondrial ATP synthase 13 Uncoupler of oxidative phosphorylation via disruption of the proton gradient 14 Nicotinic acetylcholine receptor channel blockers 8A Alkyl halides 8B Chloropicrin 8C Fluorides 9B Pyridine azomethine derivatives 10A Clofentezine Hexythiazox 10B Etoxazole 11A Bacillus thuringiensis and the insecticidal proteins they produce. 11B B. sphaericus and the insecticidal proteins they produce 12A Diafenthiuron 12B Organotin miticides 12C Propargite 12D Tetradifon Chlorfenapyr Nereistoxin analogues Methyl bromide Chloropicrin Sulfuryl fluoride Pymetrozine Clofentezine Hexythiazox Etoxazole Bacillus thuringiensis subsp. israelensis B. thuringiensis subsp. aizawai B. thuringiensis subsp. kurstaki B. thuringiensis subsp. tenebrionis B.t. crop proteins: Cry1Ac Cry2Ab Cry1F Vip3A Bacillus sphaericus Diafenthiuron Fenbutatin oxide Propargite Tetradifon Chlorfenapyr Page 3 of 7

4 15 Inhibitors of chitin biosynthesis, type 0, Benzoylureas Bistrifluron Chlorfluazuron Diflubenzuron Flufenoxuron Hexaflumuron Lufenuron Novaluron Triflumuron 16 Inhibitors of chitin biosynthesis, type 1 17 Moulting disruptor, Dipteran 18 Ecdysone receptor agonists 19 Octopamine receptor agonists 20 Mitchondrial complex III electron 21 Mitchondrial complex I electron Buprofezin Cyromazine Diacylhydrazines Amitraz 20A Hydramethylnon 20B 20C 20D Bifenazate 21A METI acaricides and insecticides 21B Rotenone Buprofezin Cyromazine Methoxyfenozide Tebufenozide Amitraz Hydramethylnon Bifenazate Fenpyroximate Pyridaben Tebufenpyrad Rotenone (Derris) 22 Voltage-dependent sodium channel blockers 23 Inhibitors of acetyl CoA carboxylase Lipid synthesis, growth regulation 22A Oxadiazines 22B Semicarbazones Tetronic and Tetramic acid derivatives Indoxacarb metaflumizone Spirotetramat Page 4 of 7

5 24 Mitochondrial complex IV electron 25 Mitochondrial complex II electron 24A Phosphides 24B Cyanides 25A Beta-ketonitrile derivatives Phosphine Aluminium phosphide Magnesium phosphide 25B Carboxanilides 28 Ryanodine receptor modulators Nerve and muscle action 29 Chordotonal organ modulators undefined target site Diamides Flonicamid Chlorantraniliprole Cyantraniliprole Flubendiamide Flonicamid UN Azadirachtin Azadirachtin Compounds of unknown or uncertain Dicofol Dicofol mode of action 2 Lime sulphur Sulphur Lime sulphur Sulphur 2 A compound with an unknown or controversial mode of action or an unknown mode of toxicity will be held in group un until evidence becomes available to enable that compound to be assigned to a more appropriate mode of action group. Page 5 of 7

6 Mode of Action Group Classification for Insecticides Active List Valid as at 7 June 2017 Active Current Group Active Current Group Abamectin 6 Fipronil 2B Acephate 1B Flonicamid 29 Acetamiprid 4A Flubendiamide 28 Allethrin 3A Flufenoxuron 15 Alpha-cypermethrin 3A Flumethrin 3A Aluminium phosphide 24A Gamma-cyhalothrin 3A Amitraz 19 Hexaflumuron 15 Azadirachtin UN Hexythiazox 10A Azamethiphos 1B Hydramethylnon 20A Azinphos methyl 1B Imidacloprid 4A Bacillus thuringiensis aizawai 11 Imiprothrin 3A Bacillus thuringiensis israelensis 11 Indoxacarb 22A Bacillus thuringiensis kurstaki 11 Lambda-cyhalothrin 3A Bacillus sphaericus 11 Lufenuron 15 Bacillus thuringiensis tenebrionis 11 Magnesium phosphide 24A Bendiocarb 1A Maldison (malathion) 1B Beta-cyfluthrin 3A Metaflumizone 22B Bifenazate 20 Methidathion 1B Bifenthrin 3A Methiocarb 1A Bioallethrin 3A Methomyl 1A Bioresmethrin 3A Methoprene 7A Bistrifluron 15 Methoxyfenozide 18 Buprofezin 16 Methyl bromide 8A Cadusafos 1B Mevinphos 1B Carbaryl 1A Milbemectin 6 Carbofuran 1A Oxamyl 1A Carbosulfan 1A Omethoate 1B Chlorantraniliprole 28 Permethrin 3A Chlorfenvinphos 1B Phorate 1B Chlorfluazuron 15 Phosmet 1B Chlorfenapyr 13 Phosphine 24A Chloropicrin 8B Pirimicarb 1A Chlorpyrifos 1B Pirimiphos-methyl 1B Chlorpyrifos-methyl 1B Prallethrin 3A Clofentezine 10A Profenofos 1B Clothianidin 4A Propargite 12C Cyantraniliprole 28 Propoxur 1A Cyfluthrin 3A Prothiofos 1B Cypermethrin 3A Pymetrozine 9B Cyromazine 17 Pyrethrins 3A Deltamethrin 3A Pyridaben 21A Diafenthiuron 12A Pyriproxyfen 7C Diazinon 1B Spinosad 5 Dichlorvos 1B Spinetoram 5 Dicofol UN Spirotetramat 23 Diflubenzuron 15 Sulfoxaflor 4C Dimethoate 1B Tau-fluvalinate 3A Dinotefuran 4A Tebufenozide 18 Emamectin benzoate 6 Tebufenpyrad 21A Esbiothrin 3A Temephos 1B Ethion 1B Terbufos 1B Etoxazole 10B Tetradifon 12D Esfenvalerate 3A Tetramethrin 3A Fenamiphos 1B Thiacloprid 4A Fenbutatin oxide 12B Thiamethoxam 4A Fenitrothion 1B Thiodicarb 1A Fenoxycarb 7B Transfluthrin 3A Fenpyroximate 21A Trichlorfon 1B Fenthion 1B Triflumuron 15 Fenvalerate 3A Zeta-cypermethrin 3A This document is a guide only and does not endorse particular products, groups of products or cultural methods in terms of their performance. Always follow the product label for specific use instructions. While all effort has been taken with the information supplied in this document no responsibility, actual or implied, is taken for the day to day accuracy of product or active constituent specific information. Readers should check with the Australian regulator s (APVMA) product database for contemporary information on products and actives. The database can be sourced through The information given in this document is provided in good faith and without any Advice given in this strategy is Valid as at 7 June All previous versions of this strategy are now invalid. Phone: info@croplife.org.au Website: Page 6 of 7

7 This document is a guide only and does not endorse particular products, groups of products or cultural methods in terms of their performance. Always follow the product label for specific use instructions. While all effort has been taken with the information supplied in this document no responsibility, actual or implied, is taken for the day to day accuracy of product or active constituent specific information. Readers should check with the Australian regulator s (APVMA) product database for contemporary information on products and actives. The database can be sourced through The information given in this document is provided in good faith and without any Advice given in this strategy is Valid as at 7 June All previous versions of this strategy are now invalid. Phone: info@croplife.org.au Website: Page 7 of 7

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