Biological Process Term Enrichment

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1 Biological Process Term Enrichment cellular protein localization cellular macromolecule localization intracellular protein transport intracellular transport generation of precursor metabolites and energy cellular macromolecule catabolic process macromolecule catabolic process protein transport establishment of protein localization protein localization regulation of cell death actin cytoskeleton organization cofactor metabolic process regulation of actin filament based process cellular homeostasis proteolysis phosphorus metabolic process phosphate metabolic process actin filament based process lipid localization lipid transport response to unfolded protein carbohydrate catabolic process lipid modification Golgi vesicle transport cofactor catabolic process ion transmembrane transport energy coupled proton transport, down electrochemical gradient lipid biosynthetic process phospholipid biosynthetic process regulation of cellular component biogenesis organophosphate metabolic process coenzyme metabolic process glycoprotein metabolic process ribonucleoprotein complex biogenesis oxidation reduction homeostatic process electron transport chain energy derivation by oxidation of organic compounds cell death death programmed cell death vesicle mediated transport cell redox homeostasis

2 Molecular Function Term Enrichment nucleoside binding purine nucleoside binding unfolded protein binding coenzyme binding cofactor binding acid amino acid ligase activity ligase activity, forming carbon nitrogen bonds ion binding cation binding metal ion binding iron sulfur cluster binding metal cluster binding fatty acid binding actin binding transcription factor binding cytoskeletal protein binding enzyme binding purine nucleotide binding ribonucleotide binding RNA binding structural constituent of ribosome nucleotide binding

3 Cellular Component Term Enrichment organelle envelope envelope mitochondrial part cytosol mitochondrial envelope mitochondrial membrane mitochondrial inner membrane organelle inner membrane mitochondrion membrane bounded vesicle cytoplasmic membrane bounded vesicle vesicle cytoplasmic vesicle Golgi apparatus endomembrane system organelle lumen intracellular organelle lumen membrane enclosed lumen organelle membrane endoplasmic reticulum cytoplasmic vesicle part perinuclear region of cytoplasm cytoplasmic vesicle membrane vesicle membrane vesicle coat apical plasma membrane membrane coat Golgi membrane nuclear envelope organelle outer membrane mitochondrial outer membrane outer membrane cell cortex cell cortex part endoplasmic reticulum lumen proton transporting ATP synthase complex mitochondrial membrane part vacuole transcription factor complex intracellular non membrane bounded organelle non membrane bounded organelle proton transporting two sector ATPase complex cell cell junction integral to organelle membrane apical part of cell nucleolus chromosome nuclear envelope endoplasmic reticulum network endoplasmic reticulum membrane internal side of plasma membrane endoplasmic reticulum part endosome Golgi apparatus part extrinsic to membrane mitochondrial matrix proteasome complex nucleoplasm nucleoplasm part ribonucleoprotein complex ribosome xclusivemsi1tg xclusivemsi1wt xclusivemsi2tg xclusivemsi2wt

4 Biological Process Term Enrichment regulation of protein polymerization regulation of actin cytoskeleton organization regulation of actin filament length regulation of cytoskeleton organization regulation of actin polymerization or depolymerization regulation of protein complex assembly small GTPase mediated signal transduction protein targeting RNA splicing coenzyme catabolic process ribonucleoside triphosphate biosynthetic process purine ribonucleoside triphosphate biosynthetic process protein modification by small protein conjugation or removal ATP metabolic process nucleoside triphosphate biosynthetic process protein modification by small protein conjugation ribonucleoside triphosphate metabolic process purine ribonucleotide metabolic process purine nucleoside triphosphate biosynthetic process ATP biosynthetic process peptide metabolic process RNA processing chromatin modification ribonucleotide metabolic process chromatin organization proteasomal protein catabolic process proteasomal ubiquitin dependent protein catabolic process purine ribonucleotide biosynthetic process biopolymer glycosylation glycosylation protein amino acid glycosylation hexose catabolic process glucose catabolic process regulation of apoptosis monosaccharide catabolic process regulation of programmed cell death regulation of actin filament polymerization ribonucleotide biosynthetic process sterol biosynthetic process regulation of organelle organization negative regulation of apoptosis alcohol catabolic process cellular carbohydrate catabolic process ER to Golgi vesicle mediated transport hexose metabolic process monosaccharide metabolic process polyol metabolic process negative regulation of programmed cell death negative regulation of cell death glycolysis fatty acid catabolic process cotranslational protein targeting to membrane sterol metabolic process phosphorylation ATP synthesis coupled proton transport tricarboxylic acid cycle acetyl CoA catabolic process aerobic respiration cellular respiration acetyl CoA metabolic process mrna metabolic process mrna processing translation ubiquitin dependent protein catabolic process protein folding cellular protein catabolic process proteolysis involved in cellular protein catabolic process protein catabolic process modification dependent protein catabolic process modification dependent macromolecule catabolic process

5 Molecular Function Term Enrichment hydrogen ion transmembrane transporter activity monovalent inorganic cation transmembrane transporter activity inorganic cation transmembrane transporter activity small conjugating protein ligase activity adenyl nucleotide binding adenyl ribonucleotide binding ATP binding purine ribonucleotide binding guanyl nucleotide binding guanyl ribonucleotide binding GTP binding ubiquitin protein ligase activity mrna binding translation factor activity, nucleic acid binding GTPase activity translation initiation factor activity magnesium ion binding P P bond hydrolysis driven transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions manganese ion binding

6 Cellular Component Term Enrichment transport vesicle membrane COPII vesicle coat coated vesicle ER to Golgi transport vesicle lysosome lytic vacuole trans Golgi network transport vesicle Golgi associated vesicle actin cytoskeleton transport vesicle cortical cytoskeleton nuclear speck nuclear body

GO ID GO term Number of members GO: translation 225 GO: nucleosome 50 GO: calcium ion binding 76 GO: structural

GO ID GO term Number of members GO: translation 225 GO: nucleosome 50 GO: calcium ion binding 76 GO: structural GO ID GO term Number of members GO:0006412 translation 225 GO:0000786 nucleosome 50 GO:0005509 calcium ion binding 76 GO:0003735 structural constituent of ribosome 170 GO:0019861 flagellum 23 GO:0005840

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