1 GO: regulation of cell size E-04 2 GO: negative regulation of cell growth GO:
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1 Table S2: The biological modulated by mir-5701 Sr. No Term Id 1 Term Name 2 Hit Gene Number 3 P-Value 4 1 GO: regulation of cell size E-04 2 GO: negative regulation of cell growth GO: regulation of anatomical structure morphogenesis GO: regulation of cellular component size GO: cellular macromolecule biosynthetic GO: negative regulation of mitotic cell cycle GO: positive regulation of cysteine-type endopeptidase activity involved in apoptotic 8 GO: regulation of cell growth GO: positive regulation of cysteine-type endopeptidase activity GO: angiogenesis GO: vasculature development GO: positive regulation of cell cycle arrest GO: negative regulation of growth GO: blood vessel morphogenesis GO: retina development in camera-type eye GO: regulation of cell morphogenesis GO: cell growth GO: anatomical structure formation involved in morphogenesis GO: positive regulation of endopeptidase activity GO: regulation of cell projection organization GO: blood vessel development GO: regulation of cysteine-type endopeptidase activity involved in apoptotic 23 GO: oligosaccharide-lipid intermediate biosynthetic GO: dolichol-linked oligosaccharide
2 biosynthetic 25 GO: regulation of vesicle-mediated transport GO: circulatory system development GO: cardiovascular system development GO: developmental growth involved in morphogenesis GO: mitotic DNA damage checkpoint GO: dolichol biosynthetic GO: negative regulation of mitotic cell cycle phase transition GO: positive regulation of peptidase activity GO: regulation of extent of cell growth GO: regulation of cellular macromolecule biosynthetic GO: mitotic cell cycle checkpoint GO: mitotic DNA integrity checkpoint GO: brain development GO: neuron projection morphogenesis GO: regulation of cell cycle arrest GO: positive regulation of hydrolase activity GO: axon guidance GO: regulation of cysteine-type endopeptidase activity GO: neuron projection guidance GO: regulation of anatomical structure size GO: negative regulation of cell cycle phase transition GO: protein K63-linked deubiquitination GO: extrinsic apoptotic signaling pathway GO: polyprenol biosynthetic GO: glycosylation GO: glycoprotein biosynthetic GO: negative regulation of G2/M transition of mitotic cell cycle GO: negative regulation of cellular macromolecule biosynthetic GO: cell morphogenesis involved in
3 neuron differentiation 54 GO: regulation of gene expression GO: negative regulation of cell cycle G2/M phase transition GO: regulation of exocytosis GO: head development GO: nervous system development GO: sensory organ development GO: regulation of developmental growth GO: stem cell division GO: negative regulation of cell cycle GO: regulation of macromolecule biosynthetic GO: single-organism carbohydrate metabolic GO: positive regulation of smooth muscle cell migration GO: otolith development GO: nucleic acid-templated transcription GO: cellular localization GO: regulation of transcription, DNAtemplated GO: transcription, DNA-templated GO: salivary gland morphogenesis GO: developmental cell growth GO: response to topologically incorrect protein GO: negative regulation of neuron projection development GO: negative regulation of transcription from RNA polymerase II promoter GO: regulation of nucleic acid-templated transcription GO: negative regulation of neuron differentiation GO: positive regulation of potassium ion transport GO: branching morphogenesis of a nerve GO: mesenchymal cell proliferation involved in lung development GO: organ morphogenesis
4 82 GO: regulation of RNA biosynthetic GO: regulation of axon extension involved in axon guidance GO: cellular component morphogenesis GO: glycoprotein metabolic GO: salivary gland development GO: gene expression GO: neuron projection extension GO: regulation of RNA metabolic GO: negative regulation of macromolecule biosynthetic GO: regulation of hydrolase activity GO: dolichol metabolic GO: regulation of nitrogen compound metabolic GO: activation of cysteine-type endopeptidase activity involved in apoptotic 95 GO: regulation of potassium ion transmembrane transporter activity GO: negative regulation of nitrogen compound metabolic GO: regulation of ion transport GO: regulation of filopodium assembly GO: axon extension involved in axon guidance GO: regulation of axon guidance GO: neuron projection extension involved in neuron projection guidance 102 GO: regulation of neuron projection development GO: axonogenesis GO: regulation of neuron differentiation GO: regulation of axon extension GO: DNA damage checkpoint GO: cellular response to topologically incorrect protein GO: regulation of mitotic cell cycle GO: macromolecule glycosylation
5 110 GO: protein glycosylation GO: positive regulation of axon guidance GO: commissural neuron axon guidance GO: positive regulation of axon extension involved in axon guidance GO: dolichyl diphosphate metabolic GO: dolichyl diphosphate biosynthetic GO: positive regulation of ion transport GO: RNA biosynthetic GO: negative regulation of cell projection organization GO: neuron development GO: regulation of transport GO: cellular protein complex assembly GO: regulation of growth GO: protein modification by small protein removal GO: clathrin-mediated endocytosis GO: regulation of nucleobase-containing compound metabolic GO: cellular response to inorganic substance GO: mitotic cell cycle GO: negative regulation of G1/S transition of mitotic cell cycle GO: regulation of cellular component organization GO: cell projection organization GO: negative regulation of macromolecule metabolic GO: neuron projection development GO: DNA integrity checkpoint GO: negative regulation of developmental GO: prostate gland development GO: heart development GO: negative regulation of cellular biosynthetic GO: negative regulation of cell cycle G1/S phase transition
6 139 GO: central nervous system development GO: regulation of extrinsic apoptotic signaling pathway GO: positive regulation of developmental growth GO: negative regulation of gene expression GO: cellular response to oxidative stress GO: vesicle mediated transport in synapse GO: cell cycle checkpoint GO: regulation of epithelial cell proliferation involved in lung morphogenesis 147 GO: polyprenol metabolic GO: cell morphogenesis GO: regulation of cell projection assembly GO: axon development GO: vesicle-mediated transport GO: exocrine system development GO: regulation of endopeptidase activity GO: synapse organization GO: regulation of signaling GO: positive regulation of calcium ion transport GO: negative regulation of biosynthetic GO: regulation of homeostatic GO: cellular macromolecular complex assembly GO: regulation of axonogenesis GO: DNA damage response, signal transduction by p53 class mediator GO: thrombin receptor signaling pathway GO: epithelial cell proliferation involved in lung morphogenesis GO: kregulation of apoptotic signaling pathway The putative target of mir-5701 was selected using 5 target prediction tools and minimum
7 stringency in starbase v2.0. Targets were uploaded DAVID platform and clustered into the biological es. 1. Identification number of the GO term. 2. The term nomenclature. 3. Target gene number that belongs to same GO term. 4. P-value of the GO term prediction.
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