SUPPLEMENTARY INFORMATION

Size: px
Start display at page:

Download "SUPPLEMENTARY INFORMATION"

Transcription

1 doi:1.138/nture11444 CMKIIN Gold prticles/ mitochondril re ( m ) CMKIIN mtcmkiin mtcmkiin SERCA ATP synthse HA mitoplsts mtcmkiin CMKIIN cytosolic mtcmkiin CMKIIN 97 kdl 64 kdl 51 kdl 14 kdl 6 kdl Supplementl Figure 1. CMKIIN is expressed in mitochondri of CMKIIN nd mtcmkiin mouse herts.. Representtive TEM imges of mitochondri isolted from herts showing HA-tgged CMKIIN expression in CMKIIN nd mtcmkiin trnsgenic mice, ut not in mice. Gold leling on mitochondri is mrked y lck circles. Summry dt (upper right) showing HA stining for n = 5 fields per condition, n = 6 herts/genotype, (p <.1). Dt represent men ± s.e.m.. Western nlysis of mitoplst lyste from, mtcmkiin nd CMKIIN herts. HA ntiody recognizes HA-CMKIIN in mitoplst nd cytosolic lystes from CMKIIN trnsgenic herts ut only in mitoplst lystes from mtcmkiin trnsgenic herts. HA ws not detected in lystes from herts. SERCA, n SR protein, is present in cytosol nd sent in mitochondril frctions. Inner mitochondril protein, ATP synthse (5), is present only in mitoplst frctions. 1

2 1 nd nd CMKIIN nd Reperfusion5 mn LVDP (mm hg) seline ischemi c Percent recovery in LVDP n = CMKIIN 1 1 d CMKIIN e f. g time (min) reperfusion CMKIIN CMKIIN. µm h Mitochondri injury score LVDP (mm hg) mm 1 Percent infrcted tissue 5 5 n = 3 CMKIIN CMKIIN Cspse 9 ctivity/ µg protein 1.1 n = n = CMKIIN CMKIIN Supplementl Figure. Hert function is eqully mintined fter ischemi nd reperfusion injury (I/R) y CMKII inhiition (CMKIIN) or cyclosporin A ().. Representtive left ventriculr developed pressure (LVDP) trces from herts nd CMKIIN-expressing herts perfused with or ( µm). The concentrtion of in the coronry perfuste is sed on lood serum levels of min fter injection in the study y Piot et l. 8.. Expnded LVDP trces efore nd fter I/R from time-points 1 nd (with rrows) in pnel. c. LVDP recovery following I/R s percentge of the seline vlue (p =.9). Numerls indicte numer of mesurements/group. d. Representtive triphenyl tetrzolium chloride (TTC) stined hert sections. The drk red stining represents living myocrdium, the solid lck outlines form oundries demrcting vile from ded tissue nd the dotted lines indicte totl re t risk. e. Summry dt from TTC stined herts with reltive re of infrct normlized to. Infrcted re ws mesured s percentge of totl t risk myocrdium (indicted y the dshed lines in pnel d, p <.1). f. Cspse 9 ctivity from herts treted s in pnel (p =.34). g. Representtive trnsmission electron microscopy (TEM) imges from herts treted s in pnel. h. Summry mitochondri injury scores for TEM studies y the following criteri: = no detectle disruption in ny mitochondri/field, 1 = criste disrupted in one mitochondrion/field, = disruption in >1 mitochondrion/field, 3 = 1 nd < 5% ruptured mitochondri/field nd 4 = 5% mitochondri ruptured/field (p =.8, out 5 mitochondri from 1 rndom fields were counted/genotype nd tretment). Dt represent men ± s.e.m.

3 Percent +dp/dt mx CMKIIN Percent -dp/dt mx CMKIIN dp/dt mx (mmhg/s) CMKIIN -dp/dt mx (mmhg/s) CMKIIN LVDP (mmhg) CMKIIN Supplementl Figure 3. Mechnicl function in isolted herts is mintined fter ischemi nd reperfusion y CMKIIN expression in trnsgenic herts or y in herts.. Percent recovery of mximum contrctility (+dp/dtmx) nd relxtion (-dp/dtmx, from time points 1 nd, see Supplementry Fig. ) in mouse herts sujected to I/R injury.. Bseline recordings for ech of the prmeters. p <.1. Numerls in rs indicte the numer of herts studied. Dt represent men ± s.e.m. 3

4 CMKII coxiv R-IgG c SERCA Clnexin Totl Mitoplst Mitochondril Cytosol ] 97 SR 97 proteins d.5 µm. µm Totl Mitoplst Mitochondril Cytosol e.15 Gold prticles/mitochondril re ( m ) CMKIICoxIV R IgG CMKII nucleolr mfn1 VDAC CoxIV 51 nucler 8] protein 97 mitochondril 8]proteins 14 pmol/min/µg.1.5. mtcmkiin Supplementl Figure 4. CMKII ssocites with mitochondri.. Representtive immuno-em imges of isolted mitochondri with ntiodies ginst CMKII or CoxIV (rrows).. Summry dt of gold leling for CMKII, using CoxIV nd rit IgG primry ntiodies s positive nd negtive controls, respectively. n = 5 fields per ntiody. c. Immunodetection of CMKII in mitochondri. Western lot shows srcoplsmic reticulum (SR) proteins in totl nd cytosol cell frctions, nucler proteins in totl nd cytosol cell frctions nd outer mitochondril proteins (mfn1 nd VDAC)predominntly in whole mitochondril frction while inner memrne spce nd inner memrne protein (CoxIV) re in oth mitochondril frctions. d. Coomssie stin of gel used in c. e. CMKII ctivity ssy mesuring C + nd clmodulin-dependent ctivity in isolted mitochondri (n = 4 mesurements/ genotype, p =.4). Dt represent men ± s.e.m. 4

5 Stte 4 (succinte) Stte 3 (succinte) Stte 3/Stte 4 (succinte) Respirtion mtcmkiin Respirtion mtcmkiin RCR mtcmkiin Stte 4 (glut/ml) Stte 3 (glut/ml) Stte 3/Stte 4 (glut/ml) 3. Respirtion 5 5 Respirtion Respirtory Control Rtio mtcmkiin mtcmkiin. mtcmkiin ADP:O rtio Respirtion mtcmkiin.5 5. mtcmkiin potentil (mv) Supplementl Figure 5. Mitochondril respirtion nd memrne potentil re not different etween nd mtcmkiin mitochondri. Both memrne potentil nd respirtion rte showed no significnt differences under stte 3 or 4 conditions or in coupling of inner mitochondril memrne potentil nd respirtion in mtcmkiin compred with control mice using succinte or glutmte nd mlte (glut/ml) s mitochondril sustrtes. The ADP:O nd the reltionship etween respirtion nd memrne potentil were determined in succinte. Mitochondril smples were prepred from nd mtcmkiin herts (n = 5 or 7 smples/group for mitochondri respiring in glut/ml or succinte, respectively) from -month old mice. Dt represent men ± s.e.m. 5

6 3 3 Normlized CG5N Normlized CG5N 1 1 mtcmkiin mtcmkiin mtcmkiin mtcmkiin Ru36 mtcmkiin Ru36 mtcmkiin Ru C + cpcity (mm) C + cpcity (mm) mtcmkiin - - mtcmkiin Supplementl Figure 6. Mitochondirl clcium retention nd cpcity in permeilized crdiomyocytes.. CG5N fluorescence trces, normlized to the first pek, show mitochondril C + uptke kinetics in sponin-permeilized Supplementl Figure nd 6. leisttin- Mitochondirl (1 clcium µm) nd thpsigrgin- (5 µm) treted crdiomyocytes isolted from or mtcmkiin trnsgenic herts. Ech C + retention nd cpcity in permeilized crdiomyocytes. trnsient ws detected with CG5N in response. CG5N fluorescence trces, to n ddition of 1 µm C + normlized to the first pek, show mitochondril C + uptke kinetics in (t times indicted). n = 4 experiments for nd mtcmkiin. sponin-permeilized nd leisttin- (1 µm) nd thpsigrgin- (5 µm) treted crdiomyocytes isolted Representtive trces shown for crdiomyocytes from nd mtcmkiin herts dditionlly treted with from or mtcmkiin trnsgenic herts. Ech C (5 µm) or Ru36 (.1 µm).. Totl extr-mitochondril + trnsient C + ws detected with CG5N in response clered y mitochondri for nd mtcmkiin to n ddition crdiomyocytes, of 1 µm C with + nd (t times without indicted)., n = 7 n (), = 4 experiments 4 ( with ), for 6 (mtcmkiin) nd mtcmkiin. nd 4 Representtive (mtcmkiin with trces ), shown p <.1 for crdiomyocytes p<.1. Dt from represent nd men mtcmkiin ± s.e.m. herts dditionlly treted with (5 µm) or Ru36 (.1 µm).. Totl extr-mitochondril C + clered y mitochondri for nd mtcmkiin crdiomyocytes, with nd without, n = 7 (), 4 ( with ), 6 (mtcmkiin) nd 4 (mtcmkiin with ), p <.1 p<.1. Dt represent men ± s.e.m. 6

7 control mtcmkiin CFP YFP CFP YFP Fluorescence (.u.) Before After Before After ATP Time [ s] 1 µm CFP YFP Fluorescence (.u.) ATP Time [ s] 1 µm Supplementl Figure 7. Mitochondril-trgeted cmeleon monitored C + uptke in HeL cells.. Trgeting of cmeleon 4mtD3cpv nd mtcmkiin or control vector (myc-pcdna) to mitochondri fter 4 h of trnsfection in HeL cells. The CFP fluorescence nd YFP FRET signls re differentilly responsive to ddition of ATP.. Representtive trcings of sl FRET (YFP, F535) nd the relted CFP (F48) fluorescence in cells trnsfected with 4mtD3cpv long with mtcmkiin or control. As indicted, cells were stimulted with 1 µm ATP. Individul fluorescent responses of 4mtD3cpv tht corresponded to the experiments shown in. Summry dt shown in Fig. 1f re tken from reltive fluorescent intensities t rrow nd rrowhed. 7

8 c I MCU (-16 mv), pa/pf 15 n.s. 1 5 Control Ru36 Voltge (mv) 1 Voltge (mv) Control K/M -1 - T/D -3 5 d Voltge (mv) I MCU (pa) Control -1 - I MCU (pa) mtcmkiin CMKIIN -5-1 I MCU (pa) c-a c-a T/D e 1 Voltge (mv) SS/AA SS/AA + T/D + T/D I MCU (pa) Supplementl Figure 8. CMKII increses I MCU.. I MCU is sensitive to Ru36 (1 nm) ut not (5 µm). n = 7 (control), 6 () nd 5 (Ru36), p <.1. Dt represent men ± s.e.m.. Representtive trces showing I MCU is incresed y constitutively ctivted CMKII mutnt (T/D), with. mm C + nd ATP, ut not with kinse inctive CMKII (K/M), CM nd ATP. c. Representtive trces showing I MCU is incresed y clyculin A (c-a) nd no dditionl increse in I MCU occurred with ddition of ctivted CMKII. d. Representtive trces showing reduced I MCU recorded with. mm C + in mitoplsts from CMKIIN nd mtcmkiin compred to herts. e. Constitutively ctive CMKII, T/D increses I MCU on mitoplsts isolted from HEK cells overexpressing MCU, ut not mutted (serines 57 nd 9 to lnines, SS/AA) MCU. 8

9 15 p =.8 Bseline LVDP (mm Hg) 1 5 mtcmkiin Supplementl Figure 9. Left ventriculr developed pressure (LVDP) recorded from nd mtcmkiin Lngendorff-perfused herts. n = 14 herts/genotype, dt represent men ± s.e.m. 9

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION SULEMENTARY INORMATION doi:1.138/nture1394 Trnsduced Mcrophges 293T-Nip trnsfectnts NAI2 N2 N5 5 Blot: Nip2 Blot: Nip5 N1 lg N6 5 c Blot: lg Blot: Nip6 Wild-type Legionell infection: fla Legionell infection:

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:.38/nture8499 doi:.38/nture8499 5 6 5 4.5 Firing rte (Hz) -67-65 -66-6 -58 V m (mv) -7-67 -68-66 -64 c Thet power (mv ) -73-69 -7-7 -7.5.8 3....9.9.4.6.6. 9 8 9 8 9 8 9 8 9 8 Supplementry Figure Firing

More information

Supporting Information. Cytosolic Irradiation of Femtosecond Laser Induces Mitochondria-dependent Apoptosis-like

Supporting Information. Cytosolic Irradiation of Femtosecond Laser Induces Mitochondria-dependent Apoptosis-like Supporting Informtion Cytosolic Irrdition of Femtosecond Lser Induces Mitochondri-dependent Apoptosis-like Cell Deth vi Intrinsic Rective Oxygen Cscdes Jonghee Yoon 1,2, Seung-wook Ryu 1,3, Seunghee Lee

More information

Supplementary Figure 1

Supplementary Figure 1 Supplementry Figure (nesthetized) (wke) Normlized mplitude.5 Pek width (ms).6.4.2 4 2 2 x 3 Wveform slope Normlized mplitude.5 Pek width (ms).6.4.2 x 3 3 2 Wveform slope c (nesthetized) d (wke) Normlized

More information

dsrna GFP 0 Ca 0 Ca 0 Ca TG Iono Time (s)

dsrna GFP 0 Ca 0 Ca 0 Ca TG Iono Time (s) Rtio (FL1/FL3) MFI dsrna GFP C dsrna dori C 1 2 1 2 Rtio (FL1/FL3) MFI C 1 2 Rtio (FL1/FL3) MFI C 1 2 C 1 2 C 1 2 Supplementry Figure 1. RNAi-medited depletion of dori hs no effet on the filling stte of

More information

Transient Stimulation of Distinct Subpopulations of Striatal Neurons Mimics Changes in the Value of Competing Actions

Transient Stimulation of Distinct Subpopulations of Striatal Neurons Mimics Changes in the Value of Competing Actions Supplementl mterils for: Trnsient Stimultion of Distinct Supopultions of Stritl Neurons Mimics Chnges in the Vlue of Competing Actions Lung-Ho Ti, A. Moses Lee,2, Nor Benvidez 3, Antonello Bonci 4,,6,

More information

Vertical uniformity of cells and nuclei in epithelial monolayers

Vertical uniformity of cells and nuclei in epithelial monolayers Supplementry informtion Verticl uniformity of cells nd nuclei in epithelil monolyers Srujn Neelm b, Peter Hyes, Qio Zhng, Richrd B. Dickinson nd Tnmy P. Lele, Figure S1. Histogrm plots compre the frequency

More information

supplementary information

supplementary information DOI: 1.138/nc8 Top-GFP!-ctenin GFP Intensity 3 1 1 3 5 6 7 8 Nucler Bet-Ctenin c MUC FABP KRT 8 5 3 6 15 1 5 LGR5 ASCL AXIN 15 5 15 5 Figure S1 TOP-GFP expression nd reltion with nucler β-ctenin, wnt trgets

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION DOI: 1.138/nc2975 GM13 / DNA F-ctin α shrna CLASP1 shrna shrna shrna CLASP1 shrna shrna e Tuulin CLASP1 CLASP1 shrna #32 shrna #33 #55 #58 Tuulin c Tuulin ppmlc E-Cdherin shrna CLASP1 shrna shrna f Golgi

More information

Supplementary Information

Supplementary Information Supplementry Informtion Coopertion of locl motions in the Hsp90 moleculr chperone ATPse mechnism Andre Schulze 1, Gerti Beliu 1, Dominic A. Helmerich 1, Jonthn Schubert 1, Lurence H. Perl 2, Chrisostomos

More information

a cacnb1 ts25/ts25 Supplemental Figure 1

a cacnb1 ts25/ts25 Supplemental Figure 1 ccn1 ts/ts α -ungrotoxin prlyzed 0.6 ΔF/F 0.0 2 ΔF/F 2 s stimulus α -ungrotoxin ccn1 ts/ts Supplementl Figure 1 CSF-cNs recorded from lrv prlyzed with α-ungrotoxin nd ccn1 mutnt lrv show no difference

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:.38/nture896 c Resting stte Resting stte Resting stte Supplementry Figure Illustrtion of pttern clssifiction nd its effects on neuronl representtions. Dynmic ctivity ptterns evoked y different stimuli

More information

Supplementary material

Supplementary material 10.1071/FP11237_AC CSIRO 2012 Accessory Puliction: Functionl Plnt Biology 2012, 39(5), 379 393. Supplementry mteril Tle S1. Effect of wter regime nd genotype on different growth prmeters: spike dry mtter

More information

polyimide Spray-coated ZrP/epoxy film Spray-coated ZrP/epoxy film glass

polyimide Spray-coated ZrP/epoxy film Spray-coated ZrP/epoxy film glass c d e polyimide Spry-coted ZrP/epoxy film glss Spry-coted ZrP/epoxy film f g Supplementry Figure 1. Opticl microscopy of smectic ( = 0.044) α-zrp/epoxy films., Trnsmission opticl microscopy (TOM) of smectic

More information

DOI:.8/nc5 Cpilities of MCAK Sidesliding, endctching on microtuules MCAKdecorted ed Functions in mitotic spindle Prometphse Slides on the microtuule surfce + Redily slides long the microtuule surfce Strongly

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:3/nture5 Δp y Pr ric ol rb in * e c mrna fold chnge reltive to wild type in NHCl medi < / >6 Supplementl Figure. Glol nd pyrimidine-relted gene expression in ΔpyrI crb* strin.. Fold chnges of RNA trnscripts

More information

SUPPLEMENTARY FIGURES

SUPPLEMENTARY FIGURES A m ultory distnce (cm ) % C enter distnce C e n te r tim e (s ) A m ultory distnce (cm ) % C enter distnce C e n te r tim e (s ) N o v e l c g e % h o m e c g e c o n s u m p tio n % M ic e fe e d in

More information

Supplementary Figures

Supplementary Figures Electronic Supplementry Mteril (ESI) for Integrtie Biology. This journl is The Royl Society of Chemistry 214 Supplementry Figures CWound Are µm2 A EGTA Low Clcium 8 1 min. fter wounding Wound + 1 min.

More information

3.94 ± 0.50 (95% CI) Correlative inhibition index (slope)

3.94 ± 0.50 (95% CI) Correlative inhibition index (slope) Supplementl Tle S. Selected rchitecturl prmeters of phy nd phyphy grown under. Vlues re mens ± SE, except for predicted primry rosette rnches where the vlues re the men with the ssocited 9% confidence

More information

SUPPLEMENTARY INFORMATION. For

SUPPLEMENTARY INFORMATION. For Eletroni Supplementry Mteril (ESI) for Journl of Mterils Chemistry B. This journl is The Royl Soiety of Chemistry 217 SUPPLEMETARY IFRMATI For Phyoynin-bsed nnorrier s new nnopltform for effiient overoming

More information

Tests for the Ratio of Two Poisson Rates

Tests for the Ratio of Two Poisson Rates Chpter 437 Tests for the Rtio of Two Poisson Rtes Introduction The Poisson probbility lw gives the probbility distribution of the number of events occurring in specified intervl of time or spce. The Poisson

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION SUPPLEMENTARY INFORMATION doi:1.138/nture261 1. Opticl chrcteriztions of 2D ilyer heterojunctions nd monolyer TMDs As shown in Figure S1, Rmn fingerprints of linking ilyer MoS2/WS2 heterostructure (leled

More information

Simple Harmonic Motion I Sem

Simple Harmonic Motion I Sem Simple Hrmonic Motion I Sem Sllus: Differentil eqution of liner SHM. Energ of prticle, potentil energ nd kinetic energ (derivtion), Composition of two rectngulr SHM s hving sme periods, Lissjous figures.

More information

supplementary information

supplementary information DOI: 1.138/n2131 Protein levels (% of ) e Full-length protein remining (%) 1 5 1 5 1 1 5 5 Hs7 Syt1 Syt2 β-atin CSP +tsyn Hs7 Syt1 Syt2 P4 rin.1.1.1 1 [Trypsin] (g/l) f +tsyn SNARE-omplexes remining (%)

More information

Control NaCl ABA * * Control 4ºC 37ºC

Control NaCl ABA * * Control 4ºC 37ºC Dul regultion of wter retention nd cell growth y stress-ssocited protein (SAP) gene in Prunus A. Lloret, A. Conejero, C. Leid, C. Petri, F. Gil-Muñoz, L. Burgos, M.L. Bdenes, nd G. Ríos.5 PpSAP Reltive

More information

350 cutoff ln(growth-ratio) Rescuer candidates that localize to the plasma membrane. 1

350 cutoff ln(growth-ratio) Rescuer candidates that localize to the plasma membrane.   1 DOI: 1.138/nc2444 Δdnf2 35 cutoff 3 25 # of strins 2 15 1 5-5 5 ln(growth-rtio) Rescuer cndidtes tht loclize to the plsm memrne. LEM3 THI73 PUN1 FUS1 ROD1 SSO1 SSO2 YPS1 PSR2 PMP3 YPS3 SNC2 LDB19 SUR7

More information

Supplementary Information

Supplementary Information Supplementry Informtion Lignd exchnge triggered controlled-relese trgeted drug delivery system sed on core shell superprmgnetic mesoporous microspheres cpped with nnoprticles Zhogng Teng, Xingng Zhu, Gengfeng

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:1.138/nture11813 NK cells NKp46 + RORγt - 5.4 RORγt + ILCs SSC-A FSC-H Linege 22.4 98.2 28.8 NKp46 1.2 15.4 NKp46 NKp46 + RORγt + ILCs NKp46 - RORγt + ILCs FSC-A FSC-A CD45 RORγt RORγt CCR6 + T-et

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION SUPPLEMENTARY INFORMATION Synthesis of metl oxide with roomtemperture photoreversile phse trnsition Shin-ichi Ohkoshi 1 *, Yoshihide Tsunouchi, 1 Tomoyuki Mtsud, 1 Kzuhito Hshimoto, 2 Asuk Nmi, 1 Fumiyoshi

More information

Colorimetric detection and separation of chiral tyrosine. based on N-acetyl-L-cysteine modified gold. nanoparticles

Colorimetric detection and separation of chiral tyrosine. based on N-acetyl-L-cysteine modified gold. nanoparticles Colorimetric detection nd seprtion of chirl tyrosine sed on N-cetyl-L-cysteine modified gold nnoprticles Hiyn Su, Qiuling Zheng nd Hiing Li* Key Lortory of Pesticide nd Chemicl Biology (CCNU), Ministry

More information

1,6. Tu18 1,2 0,8 0,4 0,0. Tu29. >10x down * 1,6. Tu43 1,2 0,8 0,4 0,0 8 0,0 1,6. Tu80 0,8 0,4 0,0

1,6. Tu18 1,2 0,8 0,4 0,0. Tu29. >10x down * 1,6. Tu43 1,2 0,8 0,4 0,0 8 0,0 1,6. Tu80 0,8 0,4 0,0 Reltive expression Tu14,9,6,3 2, Tu16 1,5 1,,5 Tu18,4 3 2 1 Tu19 >1x down * Reltive expression 3,2 Tu23 2,4 3 25 2 15 1 5 Tu28 >1x down * 4 Tu29 3 2 1 Tu31,9,6,3 Tu32 3,2 Tu33 Tu43 Tu57 Reltive expression

More information

Diverse modes of eco-evolutionary dynamics in communities of antibiotic-producing microorganisms

Diverse modes of eco-evolutionary dynamics in communities of antibiotic-producing microorganisms In the formt provided y the uthors nd unedited. ULEMENTAY INFOMATION VOLUME: 1 ATICLE NUMBE: 0189 iverse modes of eco-evolutionry dynmics in communities of ntiiotic-producing microorgnisms Klin Vetsigin

More information

6. Photoionization of acridine through singlet and triplet channels

6. Photoionization of acridine through singlet and triplet channels Chpter 6: Photoioniztion of cridine through singlet nd triplet chnnels 59 6. Photoioniztion of cridine through singlet nd triplet chnnels Photoioinztion of cridine (Ac) in queous micelles hs not yet een

More information

Muscle and serum acylcarnitine profiles in dairy cows during the periparturient period

Muscle and serum acylcarnitine profiles in dairy cows during the periparturient period Muscle nd serum cylcrnitine profiles in diry cows during the periprturient period Y. Yng, 1 C. Prehn, 2 J. Admski, 2 J. Rehge, 3 S. Dänicke, 4 H. Suerwein, 1 H. Sdri 1 1 Institute of Animl Science, Physiology

More information

Supplemental Information. Fv-clasp: An Artificially Designed Small Antibody. Fragment with Improved Production

Supplemental Information. Fv-clasp: An Artificially Designed Small Antibody. Fragment with Improved Production Structure, Volume Supplementl Informtion : An Artificilly Designed Smll Antibody Frgment with Improved Production Comptibility, Stbility, nd Crystllizbility Tko Arimori, Yu Kitgo, Mstk Umitsu, Yuki Fujii,

More information

332:221 Principles of Electrical Engineering I Fall Hourly Exam 2 November 6, 2006

332:221 Principles of Electrical Engineering I Fall Hourly Exam 2 November 6, 2006 2:221 Principles of Electricl Engineering I Fll 2006 Nme of the student nd ID numer: Hourly Exm 2 Novemer 6, 2006 This is closed-ook closed-notes exm. Do ll your work on these sheets. If more spce is required,

More information

Tremor-rich shallow dyke formation followed by silent magma flow at Bárðarbunga in Iceland

Tremor-rich shallow dyke formation followed by silent magma flow at Bárðarbunga in Iceland In the formt provided y the uthors nd unedited. SUPPLEMENTARY INFORMATION DOI: 1.138/NGEO9 Tremor-rich shllow dyke formtion followed y silent mgm flow t Bárðrung in Icelnd 1,, 1, 3 1, 1 1, NATURE GEOSCIENCE

More information

Modulation of High-Voltage Activated Ca 2+ Channels by Membrane Phosphatidylinositol 4,5-Bisphosphate

Modulation of High-Voltage Activated Ca 2+ Channels by Membrane Phosphatidylinositol 4,5-Bisphosphate Article Modultion of High-Voltge Activted 2+ hnnels y Memrne Phosphtidylinositol 4,5-isphosphte yung-hng Suh, 1, * Krin Lel, 2 nd ertil Hille 1 1 Deprtment of Physiology nd iophysics 2 Deprtment of Phrmcology

More information

Signal Flow Graphs. Consider a complex 3-port microwave network, constructed of 5 simpler microwave devices:

Signal Flow Graphs. Consider a complex 3-port microwave network, constructed of 5 simpler microwave devices: 3/3/009 ignl Flow Grphs / ignl Flow Grphs Consider comple 3-port microwve network, constructed of 5 simpler microwve devices: 3 4 5 where n is the scttering mtri of ech device, nd is the overll scttering

More information

0.1 THE REAL NUMBER LINE AND ORDER

0.1 THE REAL NUMBER LINE AND ORDER 6000_000.qd //0 :6 AM Pge 0-0- CHAPTER 0 A Preclculus Review 0. THE REAL NUMBER LINE AND ORDER Represent, clssify, nd order rel numers. Use inequlities to represent sets of rel numers. Solve inequlities.

More information

Supplementary Figure 1 Supplementary Figure 2

Supplementary Figure 1 Supplementary Figure 2 Supplementry Figure 1 Comprtive illustrtion of the steps required to decorte n oxide support AO with ctlyst prticles M through chemicl infiltrtion or in situ redox exsolution. () chemicl infiltrtion usully

More information

LAMEPS Limited area ensemble forecasting in Norway, using targeted EPS

LAMEPS Limited area ensemble forecasting in Norway, using targeted EPS Limited re ensemle forecsting in Norwy, using trgeted Mrit H. Jensen, Inger-Lise Frogner* nd Ole Vignes, Norwegin Meteorologicl Institute, (*held the presenttion) At the Norwegin Meteorologicl Institute

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION SUPPLEMENTARY INFORMATION doi: 1.138/nnno.29.451 Aove-ndgp voltges from ferroelectric photovoltic devices S. Y. Yng, 1 J. Seidel 2,3, S. J. Byrnes, 2,3 P. Shfer, 1 C.-H. Yng, 3 M. D. Rossell, 4 P. Yu,

More information

Title of file for HTML: Supplementary Information Description: Supplementary Figures. Title of file for HTML: Peer Review File Description:

Title of file for HTML: Supplementary Information Description: Supplementary Figures. Title of file for HTML: Peer Review File Description: Title of file for HTML: Supplementry Informtion Description: Supplementry Figures Title of file for HTML: Peer Review File Description: WTP SST IPO PDO WTP leds IPO PDO Supplementry Figure 1 IPO (or PDO)

More information

Direct indirect character of the band gap in methylammonium lead iodide perovskite

Direct indirect character of the band gap in methylammonium lead iodide perovskite Direct indirect chrcter of the nd gp in methylmmonium led iodide perovskite Eline M. Hutter 1, Mrí C. Gélvez-Rued 1, Ann Osherov 2, Vldimir Bulović 2, Ferdinnd C. Grozem 1, Smuel D. Strnks 2,3*, nd Tom

More information

15. Quantisation Noise and Nonuniform Quantisation

15. Quantisation Noise and Nonuniform Quantisation 5. Quntistion Noise nd Nonuniform Quntistion In PCM, n nlogue signl is smpled, quntised, nd coded into sequence of digits. Once we hve quntised the smpled signls, the exct vlues of the smpled signls cn

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:1.1/nture1 NF-κB/RE-GFP TNF-α pdna CA CA + DN d e NF-κB/RE-GFP GFP+DAPI NF-κB/RE-GFP GFP+DAPI NF-κB/RE-GFP GFP+DAPI V V DAPI DAPI NF-κB RE/GFP V V Mediosl hypothlmus Thlmus Cortex Suppl. Figure 1.

More information

Supplementary figure 1

Supplementary figure 1 Supplementry figure 1 Igf 1 mrna 5 15 1 5 Arg1 mrna 16 1 8 Col11 mrna 5 3 1 Mmp 13 mrna 15 1 5 Tslp mrna 3 1 Il5 mrna 3 1-1 Il33 mrna 6 Figure 1s. Kinetis of woun heling ftors n erly Th-type response ytokines

More information

Pharmacological evidence for a key role of voltage-gated K þ channels in the function of rat aortic smooth muscle cells

Pharmacological evidence for a key role of voltage-gated K þ channels in the function of rat aortic smooth muscle cells British Journl of Phrmcology (004) 4, 0 7 & 004 Nture Pulishing Group All rights reserved 0007 88/04 $0.00 www.nture.com/jp Phrmcologicl evidence for key role of voltge-gted K þ chnnels in the function

More information

#6A&B Magnetic Field Mapping

#6A&B Magnetic Field Mapping #6A& Mgnetic Field Mpping Gol y performing this lb experiment, you will: 1. use mgnetic field mesurement technique bsed on Frdy s Lw (see the previous experiment),. study the mgnetic fields generted by

More information

b a wt ccd8 dad2 Secondary branches 15 e cd normal low b 2

b a wt ccd8 dad2 Secondary branches 15 e cd normal low b 2 A 3 1 Shoot mss (g) B Root mss (g) C 8 Primry rnhes D 8 Seonry rnhes 1 e E 8 Shoot mss/rnhes norml low 1 F 8 8 Shoot mss/root mss 8 8 Supplementl Figure 1 Aitionl phenotypi t reore from the plnts esrie

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:10.1038/nture10735 KCNH ERG herg3 merg2 herg1 SpIH rhcn3 hhcn1 mhcn2 rhcn4 HCN zelk ELK helk1 helk2 melk3 hcngb3 CNGB1 meag1 meag2 EAG CNGA1 CNGA3 CNGA2 hcnga4 CNG Reltive Conductnce (G/Gmx) 1.0 0.8

More information

Silicon Nanowire Based Single-Molecule SERS Sensor

Silicon Nanowire Based Single-Molecule SERS Sensor Supporting informtion Silicon Nnowire Bsed Single-Molecule SERS Sensor Hui Wng, Xuemei Hn, Xuemei Ou, Chun-Sing Lee, Xiohong Zhng* nd Shuit-Tong Lee S1, A series of Si nnowires coted with compct ggregtes

More information

Supplementary Information. DNA interaction of non-chelating tinidazole-based coordination compounds. Structural, redox and cytotoxic properties.

Supplementary Information. DNA interaction of non-chelating tinidazole-based coordination compounds. Structural, redox and cytotoxic properties. Electronic Supplementry Mteril (ESI) for Dlton Trnsctions. This journl is The Royl Society of Chemistry 2018 Supplementry Informtion DNA interction of non-chelting tinidzole-bsed coordintion compounds.

More information

Scientific notation is a way of expressing really big numbers or really small numbers.

Scientific notation is a way of expressing really big numbers or really small numbers. Scientific Nottion (Stndrd form) Scientific nottion is wy of expressing relly big numbers or relly smll numbers. It is most often used in scientific clcultions where the nlysis must be very precise. Scientific

More information

Forces from Strings Under Tension A string under tension medites force: the mgnitude of the force from section of string is the tension T nd the direc

Forces from Strings Under Tension A string under tension medites force: the mgnitude of the force from section of string is the tension T nd the direc Physics 170 Summry of Results from Lecture Kinemticl Vribles The position vector ~r(t) cn be resolved into its Crtesin components: ~r(t) =x(t)^i + y(t)^j + z(t)^k. Rtes of Chnge Velocity ~v(t) = d~r(t)=

More information

AP Physics C: Electricity & Magnetism 1999 Free-Response Questions

AP Physics C: Electricity & Magnetism 1999 Free-Response Questions AP Physics C: Electricity & Mgnetism 1999 Free-esponse Questions The mterils included in these files re intended for non-commercil use by AP techers for course nd exm preprtion; permission for ny other

More information

7.1 Integral as Net Change and 7.2 Areas in the Plane Calculus

7.1 Integral as Net Change and 7.2 Areas in the Plane Calculus 7.1 Integrl s Net Chnge nd 7. Ares in the Plne Clculus 7.1 INTEGRAL AS NET CHANGE Notecrds from 7.1: Displcement vs Totl Distnce, Integrl s Net Chnge We hve lredy seen how the position of n oject cn e

More information

Supplementary Information

Supplementary Information Supplementry Informtion Spontneously mplified homochirl orgnic-inorgnic nno-helix complex vi self-prolifertion Hlei Zhi, Yn Qun, Li Li, Xing-Yng Liu, Xurong Xu c nd Ruikng Tng*,c Centre for Biomterils

More information

Understanding the relationship between floral fragrance, ethylene production and vase life of cut rose flowers

Understanding the relationship between floral fragrance, ethylene production and vase life of cut rose flowers Ethylene, Frgrnce nd Vse Life of Cut Rose Flowers 9/27/216 Progress Report Understnding the reltionship between florl frgrnce, ethylene production nd vse life of cut rose flowers An Mri Bord Dvid Clrk

More information

Reducing Nonpoint Source Pollution through Effective Ditch Management

Reducing Nonpoint Source Pollution through Effective Ditch Management Reducing Nonpoint Source Pollution through Effective Ditch Mngement Meliss Huert DNREC Division of Wtershed Stewrdship Dringe Progrm University of Delwre Artificil Dringe in Delwre Engineered system to

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION DOI: 1.138/NMAT3984 Supplementry Informtion for Improved performnce nd stility in quntum dot solr cells through nd lignment engineering Chi- Ho M. Chung 1, Ptrick R. Brown 2, Vldimir Bulović 3 & Moungi

More information

Network Analysis and Synthesis. Chapter 5 Two port networks

Network Analysis and Synthesis. Chapter 5 Two port networks Network Anlsis nd Snthesis hpter 5 Two port networks . ntroduction A one port network is completel specified when the voltge current reltionship t the terminls of the port is given. A generl two port on

More information

The Thermodynamics of Aqueous Electrolyte Solutions

The Thermodynamics of Aqueous Electrolyte Solutions 18 The Thermodynmics of Aqueous Electrolyte Solutions As discussed in Chpter 10, when slt is dissolved in wter or in other pproprite solvent, the molecules dissocite into ions. In queous solutions, strong

More information

3.2.2 Kinetics. Maxwell Boltzmann distribution. 128 minutes. 128 marks. Page 1 of 12

3.2.2 Kinetics. Maxwell Boltzmann distribution. 128 minutes. 128 marks. Page 1 of 12 3.. Kinetics Mxwell Boltzmnn distribution 8 minutes 8 mrks Pge of M. () M On the energy xis E mp t the mximum of the originl pek M The limits for the horizontl position of E mp re defined s bove the word

More information

Calpain Inhibitors and Modulation of Ischaemia Reperfusion Induced Apoptosis and Necrotic Myocardial Cell Injury

Calpain Inhibitors and Modulation of Ischaemia Reperfusion Induced Apoptosis and Necrotic Myocardial Cell Injury IOSR Journl of Phrmcy nd Biologicl Sciences (IOSR-JPBS) e-issn: 2278-38, p-issn:2319-7676. Volume 1, Issue 6 Ver. II (Nov - Dec. 215), PP 163-169 www.iosrjournls.org Clpin Inhiitors nd Modultion of Ischemi

More information

THE RELATIONSHIP BETWEEN PHOSPHATE ABSORPTION AND OXYGEN UPTAKE IN EXCISED BEECH MYCORRHIZAS

THE RELATIONSHIP BETWEEN PHOSPHATE ABSORPTION AND OXYGEN UPTAKE IN EXCISED BEECH MYCORRHIZAS New Phytol. (\98\)S8, 67-68\ 67 THE RELATIONSHIP BETWEEN PHOSPHATE ABSORPTION AND OXYGEN UPTAKE IN EXCISED BEECH MYCORRHIZAS BY J. L. HARLEY AND C. C. MCCREADY Deprtments of Forestry nd Botny, South Prks

More information

Physics 1402: Lecture 7 Today s Agenda

Physics 1402: Lecture 7 Today s Agenda 1 Physics 1402: Lecture 7 Tody s gend nnouncements: Lectures posted on: www.phys.uconn.edu/~rcote/ HW ssignments, solutions etc. Homework #2: On Msterphysics tody: due Fridy Go to msteringphysics.com Ls:

More information

u( t) + K 2 ( ) = 1 t > 0 Analyzing Damped Oscillations Problem (Meador, example 2-18, pp 44-48): Determine the equation of the following graph.

u( t) + K 2 ( ) = 1 t > 0 Analyzing Damped Oscillations Problem (Meador, example 2-18, pp 44-48): Determine the equation of the following graph. nlyzing Dmped Oscilltions Prolem (Medor, exmple 2-18, pp 44-48): Determine the eqution of the following grph. The eqution is ssumed to e of the following form f ( t) = K 1 u( t) + K 2 e!"t sin (#t + $

More information

Chapter 9: Inferences based on Two samples: Confidence intervals and tests of hypotheses

Chapter 9: Inferences based on Two samples: Confidence intervals and tests of hypotheses Chpter 9: Inferences bsed on Two smples: Confidence intervls nd tests of hypotheses 9.1 The trget prmeter : difference between two popultion mens : difference between two popultion proportions : rtio of

More information

Physics 202H - Introductory Quantum Physics I Homework #08 - Solutions Fall 2004 Due 5:01 PM, Monday 2004/11/15

Physics 202H - Introductory Quantum Physics I Homework #08 - Solutions Fall 2004 Due 5:01 PM, Monday 2004/11/15 Physics H - Introductory Quntum Physics I Homework #8 - Solutions Fll 4 Due 5:1 PM, Mondy 4/11/15 [55 points totl] Journl questions. Briefly shre your thoughts on the following questions: Of the mteril

More information

The role of ammonia in plant physiology

The role of ammonia in plant physiology The role of mmoni in plnt physiology Ineke Stulen, An Cstro, nd Luit J. De Kok Lortory of Plnt Physiology University of Groningen The Netherlnds N is essentil mino cids nd proteins N uptke nd ssimiltion

More information

Thermal Stability of Ti-C-Ni-Cr and Ti-C-Ni-Cr-Al-Si Nanocomposite Coatings

Thermal Stability of Ti-C-Ni-Cr and Ti-C-Ni-Cr-Al-Si Nanocomposite Coatings Journl of Physics: Conference Series PAPER OPEN ACCESS Therml Stility of Ti-C-Ni-Cr nd Ti-C-Ni-Cr-Al-Si Nnocomposite Cotings To cite this rticle: A V Andreev et l 2015 J. Phys.: Conf. Ser. 652 012057 View

More information

Supporting Information

Supporting Information Supporting Informtion Ultrfst nd Stble CO Cpture Using Alkli Metl Slt-Promoted MgO-CCO 3 Sorbents Hongjie Cui, Qiming Zhng, Yunwu Hu, Chong Peng, Xingchen Fng, Zhenmin Cheng, Vldimir V. Glvit nd Zhiming

More information

Derivations for maximum likelihood estimation of particle size distribution using in situ video imaging

Derivations for maximum likelihood estimation of particle size distribution using in situ video imaging 2 TWMCC Texs-Wisconsin Modeling nd Control Consortium 1 Technicl report numer 27-1 Derivtions for mximum likelihood estimtion of prticle size distriution using in situ video imging Pul A. Lrsen nd Jmes

More information

Temperature influence compensation in microbolometer detector for image quality enhancement

Temperature influence compensation in microbolometer detector for image quality enhancement .26/qirt.26.68 Temperture influence compenstion in microolometer detector for imge qulity enhncement More info out this rticle: http://www.ndt.net/?id=2647 Astrct y M. Krupiński*, T. Sosnowski*, H. Mdur*

More information

Electronic Supplementary Information

Electronic Supplementary Information Electronic Supplementry Informtion Assemling cron-coted hollow α-fe 2 nnohorns on the CNT ckone for superior lithium storge cpility Corresponding uthor: Xiong Wen (Dvid) Lou* School of Chemicl nd Biomedicl

More information

Fully Kinetic Simulations of Ion Beam Neutralization

Fully Kinetic Simulations of Ion Beam Neutralization Fully Kinetic Simultions of Ion Bem Neutrliztion Joseph Wng University of Southern Cliforni Hideyuki Usui Kyoto University E-mil: josephjw@usc.edu; usui@rish.kyoto-u.c.jp 1. Introduction Ion em emission/neutrliztion

More information

THE EFFECT OF GRADED DIETARY LEVELS OF VITAMIN A, GIVEN TO EARLY SEA BREAM (Sparus aurata) LARVAE ON SKELETAL DEFORMITIES AND GENOMIC EXPRESSION

THE EFFECT OF GRADED DIETARY LEVELS OF VITAMIN A, GIVEN TO EARLY SEA BREAM (Sparus aurata) LARVAE ON SKELETAL DEFORMITIES AND GENOMIC EXPRESSION THE EFFECT OF GRADED DIETARY LEVELS OF VITAMIN A, GIVEN TO EARLY SEA BREAM (Sprus urt) LARVAE ON SKELETAL DEFORMITIES AND GENOMIC EXPRESSION B. Ginzourg, W.M. Koven, S. Fontgne, A. Sgi, D. M. Power nd

More information

THE BREATHER STATISTICS IN CRYSTALS FAR AWAY FROM EQUILIBRIUM

THE BREATHER STATISTICS IN CRYSTALS FAR AWAY FROM EQUILIBRIUM TH RATHR STATISTICS IN CRYSTALS FAR AWAY FROM QUILIRIUM Vldimir Dubinko NSC Khrkov Institute of Physics nd Technology, Khrkov, Ukrine ASTRACT The sttistics of discrete brethes (Ds) formed by therml spikes

More information

SUPPLEMENTARY INFORMATION

SUPPLEMENTARY INFORMATION doi:10.1038/nture11097 Supplementl Text Supplementry Figure 8 shows the zonl nnul men ensemle men temperture trends for the CAM individul forcing experiments. Both lck cron (BC) nd tropospheric ozone (TO3)

More information

Lecture INF4350 October 12008

Lecture INF4350 October 12008 Biosttistics ti ti Lecture INF4350 October 12008 Anj Bråthen Kristoffersen Biomedicl Reserch Group Deprtment of informtics, UiO Gol Presenttion of dt descriptive tbles nd grphs Sensitivity, specificity,

More information

Fig. 1. Open-Loop and Closed-Loop Systems with Plant Variations

Fig. 1. Open-Loop and Closed-Loop Systems with Plant Variations ME 3600 Control ystems Chrcteristics of Open-Loop nd Closed-Loop ystems Importnt Control ystem Chrcteristics o ensitivity of system response to prmetric vritions cn be reduced o rnsient nd stedy-stte responses

More information

Minimum Energy State of Plasmas with an Internal Transport Barrier

Minimum Energy State of Plasmas with an Internal Transport Barrier Minimum Energy Stte of Plsms with n Internl Trnsport Brrier T. Tmno ), I. Ktnum ), Y. Skmoto ) ) Formerly, Plsm Reserch Center, University of Tsukub, Tsukub, Ibrki, Jpn ) Plsm Reserch Center, University

More information

Genetic Programming. Outline. Evolutionary Strategies. Evolutionary strategies Genetic programming Summary

Genetic Programming. Outline. Evolutionary Strategies. Evolutionary strategies Genetic programming Summary Outline Genetic Progrmming Evolutionry strtegies Genetic progrmming Summry Bsed on the mteril provided y Professor Michel Negnevitsky Evolutionry Strtegies An pproch simulting nturl evolution ws proposed

More information

Industrial Electrical Engineering and Automation

Industrial Electrical Engineering and Automation CODEN:LUTEDX/(TEIE-719)/1-7/(7) Industril Electricl Engineering nd Automtion Estimtion of the Zero Sequence oltge on the D- side of Dy Trnsformer y Using One oltge Trnsformer on the D-side Frncesco Sull

More information

200 points 5 Problems on 4 Pages and 20 Multiple Choice/Short Answer Questions on 5 pages 1 hour, 48 minutes

200 points 5 Problems on 4 Pages and 20 Multiple Choice/Short Answer Questions on 5 pages 1 hour, 48 minutes PHYSICS 132 Smple Finl 200 points 5 Problems on 4 Pges nd 20 Multiple Choice/Short Answer Questions on 5 pges 1 hour, 48 minutes Student Nme: Recittion Instructor (circle one): nme1 nme2 nme3 nme4 Write

More information

Homework Assignment 3 Solution Set

Homework Assignment 3 Solution Set Homework Assignment 3 Solution Set PHYCS 44 6 Ferury, 4 Prolem 1 (Griffiths.5(c The potentil due to ny continuous chrge distriution is the sum of the contriutions from ech infinitesiml chrge in the distriution.

More information

+ x 2 dω 2 = c 2 dt 2 +a(t) [ 2 dr 2 + S 1 κx 2 /R0

+ x 2 dω 2 = c 2 dt 2 +a(t) [ 2 dr 2 + S 1 κx 2 /R0 Notes for Cosmology course, fll 2005 Cosmic Dynmics Prelude [ ds 2 = c 2 dt 2 +(t) 2 dx 2 ] + x 2 dω 2 = c 2 dt 2 +(t) [ 2 dr 2 + S 1 κx 2 /R0 2 κ (r) 2 dω 2] nd x = S κ (r) = r, R 0 sin(r/r 0 ), R 0 sinh(r/r

More information

FORM FIVE ADDITIONAL MATHEMATIC NOTE. ar 3 = (1) ar 5 = = (2) (2) (1) a = T 8 = 81

FORM FIVE ADDITIONAL MATHEMATIC NOTE. ar 3 = (1) ar 5 = = (2) (2) (1) a = T 8 = 81 FORM FIVE ADDITIONAL MATHEMATIC NOTE CHAPTER : PROGRESSION Arithmetic Progression T n = + (n ) d S n = n [ + (n )d] = n [ + Tn ] S = T = T = S S Emple : The th term of n A.P. is 86 nd the sum of the first

More information

Fault Modeling. EE5375 ADD II Prof. MacDonald

Fault Modeling. EE5375 ADD II Prof. MacDonald Fult Modeling EE5375 ADD II Prof. McDonld Stuck At Fult Models l Modeling of physicl defects (fults) simplify to logicl fult l stuck high or low represents mny physicl defects esy to simulte technology

More information

Particle Lifetime. Subatomic Physics: Particle Physics Lecture 3. Measuring Decays, Scatterings and Collisions. N(t) = N 0 exp( t/τ) = N 0 exp( Γt/)

Particle Lifetime. Subatomic Physics: Particle Physics Lecture 3. Measuring Decays, Scatterings and Collisions. N(t) = N 0 exp( t/τ) = N 0 exp( Γt/) Sutomic Physics: Prticle Physics Lecture 3 Mesuring Decys, Sctterings n Collisions Prticle lifetime n with Prticle ecy moes Prticle ecy kinemtics Scttering cross sections Collision centre of mss energy

More information

Name Solutions to Test 3 November 8, 2017

Name Solutions to Test 3 November 8, 2017 Nme Solutions to Test 3 November 8, 07 This test consists of three prts. Plese note tht in prts II nd III, you cn skip one question of those offered. Some possibly useful formuls cn be found below. Brrier

More information

First compression (0-6.3 GPa) First decompression ( GPa) Second compression ( GPa) Second decompression (35.

First compression (0-6.3 GPa) First decompression ( GPa) Second compression ( GPa) Second decompression (35. 0.9 First ompression (0-6.3 GP) First deompression (6.3-2.7 GP) Seond ompression (2.7-35.5 GP) Seond deompression (35.5-0 GP) V/V 0 0.7 0.5 0 5 10 15 20 25 30 35 P (GP) Supplementry Figure 1 Compression

More information

Continuous Random Variables

Continuous Random Variables CPSC 53 Systems Modeling nd Simultion Continuous Rndom Vriles Dr. Anirn Mhnti Deprtment of Computer Science University of Clgry mhnti@cpsc.uclgry.c Definitions A rndom vrile is sid to e continuous if there

More information

: IPREM/LCABIE, UMR VNRS Université de Pau et des Pays de l Adour (UPPA), F Pau Cedex 09 b. : CEA, DAM, DIF, F Arpajon, Cedex.

: IPREM/LCABIE, UMR VNRS Université de Pau et des Pays de l Adour (UPPA), F Pau Cedex 09 b. : CEA, DAM, DIF, F Arpajon, Cedex. Are polytomic interferences, cross contmintion, mixing-effect, etc., ostcles for use of Lser ltion - ICP-MS coupling s n opertionl technique for urnium isotope rtio prticle nlysis? Arine DONARD,, Fien

More information

A5682: Introduction to Cosmology Course Notes. 4. Cosmic Dynamics: The Friedmann Equation. = GM s

A5682: Introduction to Cosmology Course Notes. 4. Cosmic Dynamics: The Friedmann Equation. = GM s 4. Cosmic Dynmics: The Friedmnn Eqution Reding: Chpter 4 Newtonin Derivtion of the Friedmnn Eqution Consider n isolted sphere of rdius R s nd mss M s, in uniform, isotropic expnsion (Hubble flow). The

More information

Deriving hydraulic conductivity function from soil column tests

Deriving hydraulic conductivity function from soil column tests Deriving hydrulic conductivity function from soil column tests Yvonne Lins, Mri Dtchev & Tom Schnz DFG Fo 444 - TP 4 Experimentelle und theoretische Untersuchungen teilgesättigter Reibungsmterilien Content

More information

Physics 137A - Quantum Mechanics - Spring 2018 Midterm 1. Mathematical Formulas

Physics 137A - Quantum Mechanics - Spring 2018 Midterm 1. Mathematical Formulas Copyright c 8 by Austin J. Hedemn Physics 7A - Quntum Mechnics - Spring 8 Midterm Mondy, Februry 6, 6:-8: PM You hve two hours, thirty minutes for the exm. All nswers should be written in blue book. You

More information

Stat3 controls lysosomal-mediated cell death in vivo

Stat3 controls lysosomal-mediated cell death in vivo L E T T E R S Stt3 controls lysosoml-medited cell deth in vivo Peter A. Kreuzler 1, Ann D. Stniszewsk 1, Wenjing Li 1, Nder Omidvr 2, Blndine Kedjour 1, Jmes Turkson 3, Vleri Poli 4, Richrd A. Flvell 5,

More information