Supplemental table S7.
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1 Supplemental table S7. GO terms significantly enriched in significantly up-regulated genes of the microarray. K: number of genes from the input cluster in the given category. F: number of total genes in the given category. Sorting Results by: the p- Biological Process GO Terms: Over Representation Value in an ascending order. Category GO Level p-value k f [GO: ] anatomical structure development E [GO: ] skeletal development E [GO: ] phosphate transport E [GO: ] organ development E [GO: ] cell adhesion E [GO: ] cell morphogenesis E [GO: ] development E [GO: ] morphogenesis E [GO: ] negative regulation of biological process E [GO: ] cell differentiation E [GO: ] regulation of biological process E [GO: ] cellular physiological process E [GO: ] inorganic anion transport E [GO: ] negative regulation of cellular process E [GO: ] biological_process E [GO: ] cellular process E [GO: ] system development E [GO: ] nervous system development E [GO: ] cell development E [GO: ] organ morphogenesis E [GO: ] physiological process E [GO: ] anion transport E [GO: ] establishment of localization E [GO: ] localization E [GO: ] cell proliferation E [GO: ] vasculature development E
2 [GO: ] enzyme linked receptor protein signaling pathway E [GO: ] blood vessel development E [GO: ] negative regulation of physiological process E [GO: ] tissue development E [GO: ] locomotion E [GO: ] cell growth E [GO: ] cell motility E [GO: ] localization of cell E [GO: ] angiogenesis E [GO: ] muscle development E [GO: ] regulation of cell size E [GO: ] regulation of organismal physiological process E [GO: ] regulation of physiological process E [GO: ] wound healing E [GO: ] response to wounding E [GO: ] neurogenesis E [GO: ] physiological response to wounding E [GO: ] generation of neurons E [GO: ] blood vessel morphogenesis E [GO: ] response to external stimulus E [GO: ] extracellular matrix organization and biogenesis E [GO: ] extracellular structure organization and biogenesis E [GO: ] regulation of cellular process E [GO: ] cell organization and biogenesis E [GO: ] tissue remodeling E [GO: ] regulation of development E [GO: ] myoblast differentiation E [GO: ] ion transport E [GO: ] cell-matrix adhesion E [GO: ] muscle cell differentiation E [GO: ] bone remodeling E [GO: ] cell-substrate adhesion E
3 [GO: ] collagen fibril organization E [GO: ] neuron differentiation E [GO: ] neurite development E [GO: ] cytoskeleton organization and biogenesis E [GO: ] actin filament organization E [GO: ] neuron development E [GO: ] growth E [GO: ] negative regulation of cellular physiological process E [GO: ] regulation of cell proliferation E [GO: ] positive regulation of biological process E [GO: ] axonogenesis E [GO: ] ossification E [GO: ] transmembrane receptor protein serine/threonine kinase signaling pathway E [GO: ] biomineral formation E [GO: ] cell migration E [GO: ] cell projection organization and biogenesis E [GO: ] neurite morphogenesis E [GO: ] cell projection morphogenesis E [GO: ] neuron morphogenesis during differentiation E [GO: ] cellular morphogenesis during differentiation E [GO: ] coagulation E [GO: ] regulation of coagulation E [GO: ] regulation of ossification E [GO: ] Wnt receptor signaling pathway E [GO: ] cell-cell signaling E [GO: ] striated muscle development E [GO: ] skeletal muscle fiber development E [GO: ] muscle fiber development E [GO: ] regulation of bone remodeling E [GO: ] negative regulation of development E [GO: ] transport E
4 [GO: ] skeletal muscle development E [GO: ] regulation of cell differentiation E [GO: ] blood coagulation E [GO: ] actin filament-based process E [GO: ] regulation of body fluids E [GO: ] hemostasis E [GO: ] axon target recognition E [GO: ] regulation of angiogenesis E [GO: ] negative regulation of Wnt receptor signaling pathway E [GO: ] transmembrane receptor protein tyrosine kinase signaling pathway E [GO: ] developmental maturation E [GO: ] cell maturation E [GO: ] negative regulation of cell differentiation E [GO: ] regulation of signal transduction E [GO: ] response to stress E [GO: ] negative regulation of angiogenesis E [GO: ] negative regulation of coagulation E [GO: ] regulation of cell growth E [GO: ] positive regulation of cell proliferation E [GO: ] integrin-mediated signaling pathway E [GO: ] regulation of progression through cell cycle E [GO: ] regulation of cell cycle E [GO: ] regulation of cellular physiological process E [GO: ] axon guidance [GO: ] positive regulation of fibroblast proliferation [GO: ] myofibril assembly [GO: ] muscle cell development [GO: ] striated muscle cell development [GO: ] regulation of Wnt receptor signaling pathway [GO: ] cell communication [GO: ] cartilage development [GO: ] fatty acid biosynthesis
5 [GO: ] negative regulation of bone remodeling [GO: ] cartilage condensation [GO: ] embryonic development (sensu Vertebrata) [GO: ] positive regulation of physiological process [GO: ] transforming growth factor beta receptor signaling pathway [GO: ] muscle contraction [GO: ] negative regulation of cell proliferation [GO: ] bone mineralization [GO: ] embryonic development [GO: ] organic acid biosynthesis [GO: ] carboxylic acid biosynthesis [GO: ] eye development [GO: ] tube development [GO: ] innate immune response [GO: ] parturition [GO: ] myelination [GO: ] negative regulation of organismal physiological process [GO: ] striated muscle cell differentiation [GO: ] regulation of bone mineralization [GO: ] behavior [GO: ] actin cytoskeleton organization and biogenesis [GO: ] embryonic development (sensu Metazoa) [GO: ] epidermis development [GO: ] acute inflammatory response [GO: ] ensheathment of neurons [GO: ] axon ensheathment [GO: ] positive regulation of development [GO: ] transmission of nerve impulse [GO: ] positive regulation of cellular process [GO: ] cell cycle [GO: ] positive regulation of organismal physiological process [GO: ] lung development
6 [GO: ] myoblast maturation [GO: ] negative regulation of signal transduction [GO: ] respiratory tube development [GO: ] myoblast development [GO: ] odontogenesis [GO: ] cell death [GO: ] death [GO: ] ectoderm development [GO: ] regulation of growth [GO: ] inflammatory response [GO: ] regulation of myoblast differentiation [GO: ] negative regulation of ossification [GO: ] regulation of apoptosis [GO: ] blood vessel maturation [GO: ] arachidonic acid metabolism [GO: ] regulation of programmed cell death [GO: ] regulation of fibroblast proliferation [GO: ] fibroblast proliferation [GO: ] substrate-bound cell migration [GO: ] regulation of catalytic activity [GO: ] circulation [GO: ] regulation of action potential [GO: ] fatty acid metabolism [GO: ] eye development (sensu Mammalia) [GO: ] regulation of neurogenesis [GO: ] T-helper 1 type immune response [GO: ] hair follicle maturation [GO: ] fatty acid desaturation [GO: ] phosphoinositide-mediated signaling [GO: ] peripheral nervous system development [GO: ] eye morphogenesis [GO: ] organismal physiological process
7 [GO: ] eye development (sensu Vertebrata) [GO: ] proteolysis [GO: ] embryonic organ morphogenesis [GO: ] positive regulation of cell migration [GO: ] prostaglandin metabolism [GO: ] prostanoid metabolism [GO: ] intracellular signaling cascade [GO: ] neuroblast proliferation (sensu Vertebrata) [GO: ] substrate-bound cell migration, cell extension [GO: ] nerve development [GO: ] negative regulation of myoblast differentiation [GO: ] positive regulation of smooth muscle cell proliferation [GO: ] long-chain fatty acid biosynthesis [GO: ] defense response to fungus [GO: ] complement activation [GO: ] activation of plasma proteins during acute inflammatory response [GO: ] positive regulation of immune response [GO: ] positive regulation of immune system process [GO: ] regulation of cell motility [GO: ] sensory organ development [GO: ] response to fungus [GO: ] somitogenesis [GO: ] complement activation, classical pathway [GO: ] apoptosis [GO: ] negative regulation of apoptosis [GO: ] anti-apoptosis [GO: ] cell-cell adhesion [GO: ] adaptive immune response (sensu Gnathostomata) [GO: ] adaptive immune response [GO: ] humoral immune response mediated by circulating immunoglobulin [GO: ] ureteric bud development [GO: ] positive regulation of enzyme activity
8 [GO: ] negative regulation of programmed cell death [GO: ] regulation of locomotion [GO: ] eye morphogenesis (sensu Mammalia) [GO: ] fibroblast growth factor receptor signaling pathway [GO: ] response to mechanical stimulus [GO: ] programmed cell death [GO: ] odontogenesis (sensu Vertebrata) [GO: ] cardioblast differentiation [GO: ] positive regulation of bone mineralization [GO: ] oogenesis (sensu Mammalia) [GO: ] platelet-derived growth factor receptor signaling pathway [GO: ] telencephalon development [GO: ] fibrinolysis [GO: ] regulation of transcription factor activity [GO: ] icosanoid metabolism [GO: ] eye morphogenesis (sensu Vertebrata) [GO: ] regulation of striated muscle development [GO: ] germ cell development [GO: ] tube morphogenesis [GO: ] kidney development [GO: ] positive regulation of neurogenesis [GO: ] positive regulation of locomotion [GO: ] neuroblast proliferation [GO: ] positive regulation of cell motility [GO: ] response to heat [GO: ] signal transduction [GO: ] mesoderm development [GO: ] mechanosensory behavior [GO: ] regulation of blood coagulation [GO: ] regulation of smooth muscle cell proliferation [GO: ] positive regulation of interleukin-6 biosynthesis [GO: ] positive regulation of small GTPase mediated signal transduction
9 [GO: ] negative regulation of blood coagulation [GO: ] positive regulation of cellular physiological process [GO: ] embryonic development (sensu Mammalia) [GO: ] embryonic eye morphogenesis [GO: ] nitric oxide biosynthesis [GO: ] nitric oxide metabolism [GO: ] synaptic transmission [GO: ] microtubule-based process [GO: ] negative regulation of cell adhesion [GO: ] regulation of protein kinase activity [GO: ] locomotory behavior [GO: ] embryonic organ development [GO: ] regulation of muscle contraction [GO: ] regulation of cell migration
1 GO: regulation of cell size E-04 2 GO: negative regulation of cell growth GO:
Table S2: The biological modulated by mir-5701 Sr. No Term Id 1 Term Name 2 Hit Gene Number 3 P-Value 4 1 GO:0008361 regulation of cell size 9 4.37E-04 2 GO:0030308 negative regulation of cell growth 8
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